Research

Research at Boston Children's Hospital

The research enterprise at Boston Children’s Hospital, comprising more than 3,000 researchers, is the world’s largest at a pediatric center. Our work is fueled by a deep understanding of disease biology coupled with world-class discovery platforms, including genetics and genomics, gene editing, bioinformatics, proteomics, bioengineering, image analysis, biobanks, disease-specific stem cell lines, and a range of animal models. We have special expertise in rare disease discovery, a robust Translational Research Program and large, diverse patient populations for clinical research and trials.
researchers

More than 3,000 researchers and scientific staff

research space

1 million square feet of research space — and growing

Boston Children's research funding

$423 million in research funding in FY2020 — #1 in NIH funding for pediatric research

Boston Children's Journal articles

3,400 articles/year in peer reviewed journals — the most of any pediatric hospital

Boston Children's inventions

149 new inventions in FY2020 alone

iPSC derived airway infected with SARS-CoV-2. Image: Ruobing Wang, Boston Children’s Hospital

COVID-19 Research

As of March 2021, Boston Children’s Hospital had produced 1,127 COVID-19-related research publications, according to Erudera. These range from molecular investigations of SARS-CoV-2 and the immune response to large-scale clinical studies of the effects of COVID-19 in children.

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Research Highlights

From our labs and clinics: 10 research advances in 2021

Science can be a long process, so when lab discoveries advance on the road to clinical application, it’s cause to celebrate. A recap of 10 successes poised to change medicine.

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New research NETs a fresh angle for treating severe inflammation

Serious infections can trigger a runaway inflammatory reaction that can do more harm than the infection itself. New research suggests a novel way to block this response with an existing drug.

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Finding new targets for acute myeloid leukemia in children

The state of care for acute myeloid leukemia has changed little in decades. But that could change: a search for genes AML needs for basic survival turned up two strong therapeutic leads.

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An image worth 1,000 words?

The 2021 Science Media Exhibition solicited more than 40 science image submissions from research laboratories and programs throughout Boston Children’s Hospital. The images here were presented live during a virtual event held in June in conjunction with Dr. M. Judah Folkman Research Day.

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BCH Innovation News @BCH_Innovation 1/20/2022 4:30:01 PM
Urine #biomarkers — proteins that distinguish people with & without #concussion — could revolutionize concussion di… https://t.co/AWVKMalOmL
BCH Innovation News @BCH_Innovation 1/15/2022 10:00:01 PM
Benefits outweigh the risks of #COVID19 vaccination in teens and young adults. Learn more from three major research… https://t.co/WBr582EMer
BCH Innovation News @BCH_Innovation 1/14/2022 10:00:01 PM
Three major studies—in @CircAHA , @CDCMMWR and @NEJM – strongly support #COVID19 vaccination:… https://t.co/QynZO8Vgo6
BCH Innovation News @BCH_Innovation 1/10/2022 4:39:25 PM
RT @DFBC_PedCare: New research from @Bando_Lab shows that challenges remain in using liquid biopsies to genetically characterize pediatric…
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Are #sepsis and #thrombosis two sides of the same coin? Valentina Poli, @Lo_Zanzi & colleagues unpack the dual hemo… https://t.co/3iW9X6M5jk
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Through a grant from NHGRI @genome_gov, @BostonChildrens is providing remote genomics services to neonatologists in… https://t.co/CENCvD9QXv
The commitment and compassion with which we care for all children and families is matched only by the pioneering spirit of discovery and innovation that drives us to think differently, to find answers, and to build a better tomorrow for children everywhere.

Kevin B. Churchwell, President and CEO