Boston Children's Research

Research faculty

Research at Boston Children's Hospital

The research enterprise at Boston Children’s Hospital, comprising more than 3,000 researchers, is the world’s largest at a pediatric center. Our work is fueled by a deep understanding of disease biology coupled with world-class discovery platforms, including genetics and genomics, gene editing, bioinformatics, proteomics, bioengineering, image analysis, biobanks, disease-specific stem cell lines, and a range of animal models. We have special expertise in rare disease discovery, a robust Translational Research Program and large, diverse patient populations for clinical research and trials.

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Can deep learning algorithms translate personalized patient instructions into Spanish at a quality comparable to that of professional human translators? A new study published in JAMA Pediatrics found that while human review is still essential, these large language models could reduce the translation workload for Spanish, potentially freeing resources to s...

Boston Children's Research bch-research

Congratulations to Ellen Jopling for receiving a Banting Postdoctoral Fellowship from the Canadian government. 👏 Originally from Canada, Ellen is now a postdoc in the lab of Dr. Charles Nelson where she studies how severe early life adversity influences long-term neurobiological development. Learn more about the Nelson Lab: http://ms.spr.ly/6040sBnGe

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Published today in Cell: Researchers have discovered that the environment inside our bodies, specifically, the pH level within cells, has a powerful influence on the immune system. These findings open up a new way of thinking about how our internal environment shapes immune function, and could lead to innovative strategies for disease ...

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Autosomal dominant optic atrophy ADOA causes progressive childhood blindness — but what if we could stop it? Boston Children’s researchers Drs. Thomas Schwarz and Chen Ding have identified a key molecular target that may do just that. Learn about the breakthrough that could change treatment ⤵️

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Gene therapy that restores dopamine at the source — it’s a breakthrough for AADC deficiency, and Boston Children’s helped pioneer the approach, from surgical delivery to clinical trials to FDA approval in 2024.

This isn’t symptom management — it’s real treatment at the root of the disease. It’s a milestone for p...

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Drs. Fulton, Gonzales and Elhusseiny from Boston Children’s Hospital and their Ophthalmology colleagues published an article regarding the future of treatment for pediatric macular disorders. Pediatric macular disorders, like Stargardt disease and Best vitelliform macular dystrophy, can cause progressive central vision loss, affecting kids during childh...

Boston Children's Research bch-research

Can deep learning algorithms translate personalized patient instructions into Spanish at a quality comparable to that of professional human translators? A new study published in JAMA Pediatrics found that while human review is still essential, these large language models could reduce the translation workload for Spanish, potentially freeing resources to s...

Boston Children's Research bch-research

An exciting step forward for Autism research ⬇️. Learn more from Dr. Matthew Siegel, our Chief of Clinical Enterprise and principal investigator of the Autism Inpatient Collection in Neuroscience News.

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