Clinical Research

Shaping the future of pediatric medicine

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For 150 years, Boston Children’s has embodied a culture of scientific investigation that has shaped pediatric medicine and changed children’s lives. This legacy continues today as we lead the world in pediatric research, empowering clinicians and scientists to challenge the status quo and seek better answers for our patients.

Our research enterprise is the world's largest and most highly-funded pediatric hospital. In FY2018, we received more funding from the National Institutes of Health than any other children’s hospital in the nation. We perform research in a vast range of specialties, revolutionizing treatments for children with common conditions, such as asthma, diabetes and obesity, to children with rare and complex disorders.

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Find a clinical research study

Boston Children's leads or participates in hundreds of clinical trials. Use this database to find out which trials are recruiting, who can enroll and more.

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Resources for the research community

A central hub of resources to support the Boston Children’s research community through guidance on planning, designing, implementing and reporting.

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Recent Breakthroughs

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How does the placenta protect unborn babies from COVID-19?

Only about 5 percent of babies born to COVID-19-positive mothers become infected themselves. Elizabeth Taglauer, MD, PhD, a placental immunologist in the Division of Newborn Medicine at Boston Children’s Hospital, wants to know why these babies are so resilient.
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Examining immune responses in people hospitalized with COVID-19

Called IMPACC (IMmunoPhenotyping Assessment in a COVID-19 Cohort), the study will include up to 2,000 patients from 10 to 12 medical centers across the country. The information collected could guide new strategies for diagnosing and treating COVID-19 and possibly identify new targets for drug treatment.
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Boston Children’s Hospital leads national study on pediatric COVID-19 and MIS-C

Why are children largely spared from COVID-19 — and why do a few become extremely sick? To find out, Boston Children’s Hospital launched a national study in April to perform real-time surveillance at more than 35 U.S. children’s hospitals.
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Building on our extraordinary leadership in pediatric science at Boston Children’s, we translate our findings — and those of others — to fundamentally change how disease is treated and cured.

David A. Williams, MD
Senior Vice President and Chief Scientific Officer