Clinical Research

Shaping the future of pediatric medicine

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For 150 years, Boston Children’s has embodied a culture of scientific investigation that has shaped pediatric medicine and changed children’s lives. This legacy continues today as we lead the world in pediatric research, empowering clinicians and scientists to challenge the status quo and seek better answers for our patients.

Our research enterprise is the world's largest and most highly-funded pediatric hospital. In FY2018, we received more funding from the National Institutes of Health than any other children’s hospital in the nation. We perform research in a vast range of specialties, revolutionizing treatments for children with common conditions, such as asthma, diabetes and obesity, to children with rare and complex disorders.

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Find a clinical research study

Boston Children's leads or participates in hundreds of clinical trials. Use this database to find out which trials are recruiting, who can enroll and more.


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Resources for the research community

A central hub of resources to support the Boston Children’s research community through guidance on planning, designing, implementing and reporting.


Recent Highlights

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Risdiplam improves motor function in infants with spinal muscular atrophy

Many babies with Type 1 spinal muscular atrophy cannot hold their head up, sit, or walk. But a recent clinical trial showed improved motor function with the oral medication risdiplam — adding to a series of advancements in SMA care.
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Lead exposure remains a problem for some children

Boston Children’s has documented the effects of lead poisoning on children since the 1940s, helping to pass environmental laws in the 1970s. Yet even today, half of young children have detectable lead levels, a national study finds.
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Trial for severe asthma targets a mutation common in children of color

Building on a half-decade of science at Boston Children’s Hospital, this study will test an existing drug that reduces inflammation by blocking a receptor that is commonly mutated in Black and Latinx people.
The commitment and compassion with which we care for all children and families is matched only by the pioneering spirit of discovery and innovation that drives us to think differently, to find answers, and to build a better tomorrow for children everywhere.

Kevin B. Churchwell, President and CEO