Undergraduate Degree

  • Madison College , 1976 , Harrrisonburg , VA

Graduate Degree

  • Medical College of Virginia , 1981 , Richmond , VA

Medical School

  • Stanford Medical School , 1985 , Stanford , CA


  • University of Colorado , 1986 , Denver , CO


  • University of Colorado , 1989 , Denver , CO


Maternal Fetal Medicine
  • Maternal Fetal Medicine , 1992 , Boston , MA

Philosophy of Care

My job as a high-risk obstetrician and geneticist combines my passion for understanding complex conditions and translating that information into compassionate and patient centered care. While the individual circumstances of a specific complication and family are always unique, a team approach assures compassionate, broad reaching and patient specific support.


With early career training in human genetics, I saw the unfolding of our understanding of the deep connection between human genetics and pregnancy outcomes – both those pregnancies which proceed without complication and those with unexpected complications such as preterm delivery, preeclampsia or a fetal condition. In these settings, helping a woman and her family navigate the vast information available, prepare for her delivery and develop a support system to sustain her through this process is a challenge and a privilege. My participation with multispecialty care teams provides me daily re-enforcement of their value and the need for patients to be informed as they face a life-changing experience.

As a geneticist, we are only beginning to understand the vast range of genomic contributions to pregnancy outcomes. Continuing to explore how genetics influences a pregnancy is critical. And that what was once considered dogma should always be open for re-analysis. A highlight of my time working in the field of congenital anomalies has been with our fetal cardiac intervention program. Involving a range of specialists, our team showed that the accepted version of a birth defect as a static and predetermined event may not always be true. Some birth defects may result from progressive change through a pregnancy. For a subgroup of fetuses with hypoplastic left heart syndrome, we demonstrated that stenosis of the aortic valve can be the primary event. As the pregnancy continues progressive loss of fetal left ventricle function occurs and results in a newborn with classic HLHS. Most importantly, “in utero” valve dilation of the aortic valve stenosis can prevent further damage to the left ventricle. Over the past 15 years, this team has worked on perfecting and minimizing maternal risks of the procedure, identifying key imaging criteria, and explored at the biologic level how to differentiate the degree of fetal heart damage. As the primary fetal interventionist for this team since 2000, the progress made in both the technique and the outcomes for these children has been a gift.


  • American Board of Pediatrics, Pediatric Hematology and Oncology
  • American Board of Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology Maternal and Fetal Medicine


Publications powered by Harvard Catalyst Profiles

  1. Gray KJ, Wilkins-Haug L. Special issue on "Feto-Maternal Genomic Medicine": a decade of incredible advances. Hum Genet. 2020 Sep; 139(9):1119-1120. View abstract
  2. O'Connell AE, Guseh S, Lapteva L, Cummings CL, Wilkins-Haug L, Chan J, Peranteau WH, Almeida-Porada G, Kourembanas S. Gene and Stem Cell Therapies for Fetal Care: A Review. JAMA Pediatr. 2020 Jun 29. View abstract
  3. Wilkins-Haug L. Genetic innovations and our understanding of stillbirth. Hum Genet. 2020 Sep; 139(9):1161-1172. View abstract
  4. Pickard SS, Wong JB, Bucholz EM, Newburger JW, Tworetzky W, Lafranchi T, Benson CB, Wilkins-Haug LE, Porras D, Callahan R, Friedman KG. Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome: A Decision Analysis. Circ Cardiovasc Qual Outcomes. 2020 Apr; 13(4):e006127. View abstract
  5. Guseh SH, Friedman KG, Wilkins-Haug LE. Fetal cardiac intervention-Perspectives from a single center. Prenat Diagn. 2020 03; 40(4):415-423. View abstract
  6. Celi AC, Seely EW, Wang P, Thomas AM, Wilkins-Haug LE. Caring for Women After Hypertensive Pregnancies and Beyond: Implementation and Integration of a Postpartum Transition Clinic. Matern Child Health J. 2019 Nov; 23(11):1459-1466. View abstract
  7. Gray KJ, Wilkins-Haug LE, Herrig NJ, Vora NL. Fetal phenotypes emerge as genetic technologies become robust. Prenat Diagn. 2019 08; 39(9):811-817. View abstract
  8. Petracchi F, Sisterna S, Igarzabal L, Wilkins-Haug L. Fetal cardiac abnormalities: Genetic etiologies to be considered. Prenat Diagn. 2019 08; 39(9):758-780. View abstract
  9. Rich-Edwards JW, Stuart JJ, Skurnik G, Roche AT, Tsigas E, Fitzmaurice GM, Wilkins-Haug LE, Levkoff SE, Seely EW. Randomized Trial to Reduce Cardiovascular Risk in Women with Recent Preeclampsia. J Womens Health (Larchmt). 2019 11; 28(11):1493-1504. View abstract
  10. Jelin AC, Sagaser KG, Wilkins-Haug L. Prenatal Genetic Testing Options. Pediatr Clin North Am. 2019 04; 66(2):281-293. View abstract
  11. Friedman KG, Sleeper LA, Freud LR, Marshall AC, Godfrey ME, Drogosz M, Lafranchi T, Benson CB, Wilkins-Haug LE, Tworetzky W. Improved technical success, postnatal outcome and refined predictors of outcome for fetal aortic valvuloplasty. Ultrasound Obstet Gynecol. 2018 08; 52(2):212-220. View abstract
  12. Wilkins-Haug L, Zhang C, Cerveira E, Ryan M, Mil-Homens A, Zhu Q, Reddi H, Lee C, Bianchi DW. Biological explanations for discordant noninvasive prenatal test results: Preliminary data and lessons learned. Prenat Diagn. 2018 05; 38(6):445-458. View abstract
  13. Gray KJ, Wilkins-Haug LE. Have we done our last amniocentesis? Updates on cell-free DNA for Down syndrome screening. Pediatr Radiol. 2018 04; 48(4):461-470. View abstract
  14. Prosnitz AR, Drogosz M, Marshall AC, Wilkins-Haug LE, Benson CB, Sleeper LA, Tworetzky W, Friedman KG. Early hemodynamic changes after fetal aortic stenosis valvuloplasty predict biventricular circulation at birth. Prenat Diagn. 2018 03; 38(4):286-292. View abstract
  15. Reimers RM, Mason-Suares H, Little SE, Bromley B, Reiff ES, Dobson LJ, Wilkins-Haug L. When ultrasound anomalies are present: An estimation of the frequency of chromosome abnormalities not detected by cell-free DNA aneuploidy screens. Prenat Diagn. 2018 03; 38(4):250-257. View abstract
  16. Friedman KG, Sleeper LA, Fichorova RN, Weilnau T, Tworetzky W, Wilkins-Haug LE. Myocardial injury in fetal aortic stenosis: Insights from amniotic fluid analysis. Prenat Diagn. 2018 02; 38(3):190-195. View abstract
  17. Bunnell ME, Wilkins-Haug L, Reiss R. Should embryos with autosomal monosomy by preimplantation genetic testing for aneuploidy be transferred?: Implications for embryo selection from a systematic literature review of autosomal monosomy survivors. Prenat Diagn. 2017 12; 37(13):1273-1280. View abstract
  18. Robinson JN, Wilkins-Haug LE. Communicating risk with aneuploidy screening: things are never as simple as they appear to be. BJOG. 2018 02; 125(3):277. View abstract
  19. Lassey SC, Reiff ES, Dobson L, Bromley B, Wilkins-Haug L, Bartz D, Little SE. The influence of noninvasive prenatal testing on gestational age at time of abortion for aneuploidy. Prenat Diagn. 2017 Jul; 37(7):635-639. View abstract
  20. Guseh SH, Little SE, Bennett K, Silva V, Wilkins-Haug LE. Antepartum management and obstetric outcomes among pregnancies with Down syndrome from diagnosis to delivery. Prenat Diagn. 2017 Jul; 37(7):640-646. View abstract
  21. Reiss RE, Discenza M, Foster J, Dobson L, Wilkins-Haug L. Sex chromosome aneuploidy detection by noninvasive prenatal testing: helpful or hazardous? Prenat Diagn. 2017 May; 37(5):515-520. View abstract
  22. Bunnell M, Zhang C, Lee C, Bianchi DW, Wilkins-Haug L. Confined placental mosaicism for 22q11.2 deletion as the etiology for discordant positive NIPT results. Prenat Diagn. 2017 Apr; 37(4):416-419. View abstract
  23. Mackesy MM, Kalish BT, Tworetzky W, Sanders S, Al-Ibraheemi A, Wilkins-Haug L, Lock J, Marshall A, Benson CB. Sonographic Pulmonary Abnormalities in Fetuses With Hypoplastic Left Heart Syndrome and Intact Atrial Septum Undergoing Attempted Atrial Septostomy In Utero. Ultrasound Q. 2017 Mar; 33(1):82-85. View abstract
  24. Laraja K, Sadhwani A, Tworetzky W, Marshall AC, Gauvreau K, Freud L, Hass C, Dunbar-Masterson C, Ware J, Lafranchi T, Wilkins-Haug L, Newburger JW. Neurodevelopmental Outcome in Children after Fetal Cardiac Intervention for Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome. J Pediatr. 2017 05; 184:130-136.e4. View abstract
  25. Ordulu Z, Kammin T, Brand H, Pillalamarri V, Redin CE, Collins RL, Blumenthal I, Hanscom C, Pereira S, Bradley I, Crandall BF, Gerrol P, Hayden MA, Hussain N, Kanengisser-Pines B, Kantarci S, Levy B, Macera MJ, Quintero-Rivera F, Spiegel E, Stevens B, Ulm JE, Warburton D, Wilkins-Haug LE, Yachelevich N, Gusella JF, Talkowski ME, Morton CC. Structural Chromosomal Rearrangements Require Nucleotide-Level Resolution: Lessons from Next-Generation Sequencing in Prenatal Diagnosis. Am J Hum Genet. 2016 Nov 03; 99(5):1015-1033. View abstract
  26. Dobson LJ, Reiff ES, Little SE, Wilkins-Haug L, Bromley B. Patient choice and clinical outcomes following positive noninvasive prenatal screening for aneuploidy with cell-free DNA (cfDNA). Prenat Diagn. 2016 May; 36(5):456-62. View abstract
  27. Little S, Clapp M, Wilkins-Haug L, Zera C, Robinson J. In Reply. Obstet Gynecol. 2016 Apr; 127(4):804. View abstract
  28. Bigelow CA, Cinelli CM, Little SE, Benson CB, Frates MC, Wilkins-Haug LE. Percutaneous umbilical blood sampling: current trends and outcomes. Eur J Obstet Gynecol Reprod Biol. 2016 May; 200:98-101. View abstract
  29. Reiff ES, Little SE, Dobson L, Wilkins-Haug L, Bromley B. What is the role of the 11- to 14-week ultrasound in women with negative cell-free DNA screening for aneuploidy? Prenat Diagn. 2016 Mar; 36(3):260-5. View abstract
  30. Little SE, Zera CA, Clapp MA, Wilkins-Haug L, Robinson JN. A Multi-State Analysis of Early-Term Delivery Trends and the Association With Term Stillbirth. Obstet Gynecol. 2015 Dec; 126(6):1138-45. View abstract
  31. Jelin AC, Anderson B, Wilkins-Haug L, Schulkin J. Obstetrician and gynecologists' population-based screening practices. J Matern Fetal Neonatal Med. 2016 Mar; 29(6):875-9. View abstract
  32. Moon-Grady AJ, Morris SA, Belfort M, Chmait R, Dangel J, Devlieger R, Emery S, Frommelt M, Galindo A, Gelehrter S, Gembruch U, Grinenco S, Habli M, Herberg U, Jaeggi E, Kilby M, Kontopoulos E, Marantz P, Miller O, Otaño L, Pedra C, Pedra S, Pruetz J, Quintero R, Ryan G, Sharland G, Simpson J, Vlastos E, Tworetzky W, Wilkins-Haug L, Oepkes D. International Fetal Cardiac Intervention Registry: A Worldwide Collaborative Description and Preliminary Outcomes. J Am Coll Cardiol. 2015 Jul 28; 66(4):388-99. View abstract
  33. Bianchi DW, Chudova D, Sehnert AJ, Bhatt S, Murray K, Prosen TL, Garber JE, Wilkins-Haug L, Vora NL, Warsof S, Goldberg J, Ziainia T, Halks-Miller M. Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies. JAMA. 2015 Jul 14; 314(2):162-9. View abstract
  34. Machtinger R, Zera C, Racowsky C, Missmer S, Gargiulo A, Schiff E, Wilkins-Haug L. The effect of mode of conception on obstetrical outcomes differs by body mass index. Reprod Biomed Online. 2015 Oct; 31(4):531-7. View abstract
  35. Wilkins-Haug L, Celi A, Thomas A, Frolkis J, Seely EW. Recognition by Women's Health Care Providers of Long-Term Cardiovascular Disease Risk After Preeclampsia. Obstet Gynecol. 2015 Jun; 125(6):1287-92. View abstract
  36. Emery SP, Bahtiyar MO, Dashe JS, Wilkins-Haug LE, Johnson A, Paek BW, Moon-Grady AJ, Skupski DW, O'Brien BM, Harman CR, Simpson LL. The North American Fetal Therapy Network Consensus Statement: prenatal management of uncomplicated monochorionic gestations. Obstet Gynecol. 2015 May; 125(5):1236-43. View abstract
  37. Lee MS, Cantonwine D, Little SE, McElrath TF, Parry SI, Lim KH, Wilkins-Haug LE. Angiogenic markers in pregnancies conceived through in vitro fertilization. Am J Obstet Gynecol. 2015 Aug; 213(2):212.e1-8. View abstract
  38. Reiss R, Ahern D, Sandstrom M, Wilkins-Haug L. Recurrent enlarged nuchal translucency: first trimester presentation of a familial 15q26?qter deletion. Am J Med Genet A. 2015 Mar; 167A(3):612-6. View abstract
  39. Melamed N, Choufani S, Wilkins-Haug LE, Koren G, Weksberg R. Comparison of genome-wide and gene-specific DNA methylation between ART and naturally conceived pregnancies. Epigenetics. 2015; 10(6):474-83. View abstract
  40. Bahtiyar MO, Emery SP, Dashe JS, Wilkins-Haug LE, Johnson A, Paek BW, Moon-Grady AJ, Skupski DW, O'Brien BM, Harman CR, Simpson LL. The North American Fetal Therapy Network consensus statement: prenatal surveillance of uncomplicated monochorionic gestations. Obstet Gynecol. 2015 Jan; 125(1):118-23. View abstract
  41. Langlois S, Benn P, Wilkins-Haug L. Current controversies in prenatal diagnosis 4: pre-conception expanded carrier screening should replace all current prenatal screening for specific single gene disorders. Prenat Diagn. 2015 Jan; 35(1):23-8. View abstract
  42. Curnow KJ, Wilkins-Haug L, Ryan A, Kirkizlar E, Stosic M, Hall MP, Sigurjonsson S, Demko Z, Rabinowitz M, Gross SJ. Detection of triploid, molar, and vanishing twin pregnancies by a single-nucleotide polymorphism-based noninvasive prenatal test. Am J Obstet Gynecol. 2015 Jan; 212(1):79.e1-9. View abstract
  43. Freud LR, McElhinney DB, Marshall AC, Marx GR, Friedman KG, del Nido PJ, Emani SM, Lafranchi T, Silva V, Wilkins-Haug LE, Benson CB, Lock JE, Tworetzky W. Fetal aortic valvuloplasty for evolving hypoplastic left heart syndrome: postnatal outcomes of the first 100 patients. Circulation. 2014 Aug 19; 130(8):638-45. View abstract
  44. Guay-Woodford LM, Bissler JJ, Braun MC, Bockenhauer D, Cadnapaphornchai MA, Dell KM, Kerecuk L, Liebau MC, Alonso-Peclet MH, Shneider B, Emre S, Heller T, Kamath BM, Murray KF, Moise K, Eichenwald EE, Evans J, Keller RL, Wilkins-Haug L, Bergmann C, Gunay-Aygun M, Hooper SR, Hardy KK, Hartung EA, Streisand R, Perrone R, Moxey-Mims M. Consensus expert recommendations for the diagnosis and management of autosomal recessive polycystic kidney disease: report of an international conference. J Pediatr. 2014 Sep; 165(3):611-7. View abstract
  45. Schidlow DN, Tworetzky W, Wilkins-Haug LE. Percutaneous fetal cardiac interventions for structural heart disease. Am J Perinatol. 2014 Aug; 31(7):629-36. View abstract
  46. Bibbo C, Celi A, Thomas AM, Blake-Lamb TL, Wilkins-Haug L. Does the addition of a specialized postpartum clinic improve the care of women with preeclampsia? Obstet Gynecol. 2014 May; 123 Suppl 1:39S. View abstract
  47. Kalish BT, Tworetzky W, Benson CB, Wilkins-Haug L, Mizrahi-Arnaud A, McElhinney DB, Lock JE, Marshall AC. Technical challenges of atrial septal stent placement in fetuses with hypoplastic left heart syndrome and intact atrial septum. Catheter Cardiovasc Interv. 2014 Jul 01; 84(1):77-85. View abstract
  48. Zera CA, Seely EW, Wilkins-Haug LE, Lim KH, Parry SI, McElrath TF. The association of body mass index with serum angiogenic markers in normal and abnormal pregnancies. Am J Obstet Gynecol. 2014 Sep; 211(3):247.e1-7. View abstract
  49. Wessel AE, Mogensen KM, Rohr F, Erick M, Neilan EG, Chopra S, Levy HL, Gray KJ, Wilkins-Haug L, Berry GT. Management of a Woman With Maple Syrup Urine Disease During Pregnancy, Delivery, and Lactation. JPEN J Parenter Enteral Nutr. 2015 Sep; 39(7):875-9. View abstract
  50. Dukhovny S, Zera C, Little SE, McElrath T, Wilkins-Haug L. Eliminating first trimester markers: will replacing PAPP-A and ßhCG miss women at risk for small for gestational age? J Matern Fetal Neonatal Med. 2014 Nov; 27(17):1761-4. View abstract
  51. Little SE, Robinson JN, Puopolo KM, Mukhopadhyay S, Wilkins-Haug LE, Acker DA, Zera CA. The effect of obstetric practice change to reduce early term delivery on perinatal outcome. J Perinatol. 2014 Mar; 34(3):176-80. View abstract
  52. Benn P, Chapman AR, Erickson K, Defrancesco MS, Wilkins-Haug L, Egan JF, Schulkin J. Obstetricians and gynecologists' practice and opinions of expanded carrier testing and noninvasive prenatal testing. Prenat Diagn. 2014 Feb; 34(2):145-52. View abstract
  53. Dukhovny S, Wilkins-Haug L, Shipp TD, Benson CB, Kaimal AJ, Reiss R. Absent fetal nasal bone: what does it mean for the euploid fetus? J Ultrasound Med. 2013 Dec; 32(12):2131-4. View abstract
  54. Taglauer ES, Wilkins-Haug L, Bianchi DW. Review: cell-free fetal DNA in the maternal circulation as an indication of placental health and disease. Placenta. 2014 Feb; 35 Suppl:S64-8. View abstract
  55. Bianchi DW, Wilkins-Haug L. Integration of noninvasive DNA testing for aneuploidy into prenatal care: what has happened since the rubber met the road? Clin Chem. 2014 Jan; 60(1):78-87. View abstract
  56. Lambert-Messerlian G, Kloza EM, Williams J, Loucky J, O'Brien B, Wilkins-Haug L, Mahoney MJ, De Biasio P, Borrell A, Ehrich M, van den Boom D, Bombard AT, Deciu C, Palomaki GE. Maternal plasma DNA testing for aneuploidy in pregnancies achieved by assisted reproductive technologies. Genet Med. 2014 May; 16(5):419-22. View abstract
  57. Lynn KN, Steinkeler JA, Wilkins-Haug LE, Benson CB. Hyperreactio luteinalis (enlarged ovaries) during the second and third trimesters of pregnancy: common clinical associations. J Ultrasound Med. 2013 Jul; 32(7):1285-9. View abstract
  58. Saxena AR, Seely EW, Rich-Edwards JW, Wilkins-Haug LE, Karumanchi SA, McElrath TF. First trimester PAPP-A levels correlate with sFlt-1 levels longitudinally in pregnant women with and without preeclampsia. BMC Pregnancy Childbirth. 2013 Apr 04; 13:85. View abstract
  59. Talkowski ME, Ordulu Z, Pillalamarri V, Benson CB, Blumenthal I, Connolly S, Hanscom C, Hussain N, Pereira S, Picker J, Rosenfeld JA, Shaffer LG, Wilkins-Haug LE, Gusella JF, Morton CC. Clinical diagnosis by whole-genome sequencing of a prenatal sample. N Engl J Med. 2012 Dec 06; 367(23):2226-32. View abstract
  60. Stoffan AP, Wilson JM, Jennings RW, Wilkins-Haug LE, Buchmiller TL. Does the ex utero intrapartum treatment to extracorporeal membrane oxygenation procedure change outcomes for high-risk patients with congenital diaphragmatic hernia? J Pediatr Surg. 2012 Jun; 47(6):1053-7. View abstract
  61. Chang G, Orav EJ, Jones JA, Buynitsky T, Gonzalez S, Wilkins-Haug L. Self-reported alcohol and drug use in pregnant young women: a pilot study of associated factors and identification. J Addict Med. 2011 Sep; 5(3):221-6. View abstract
  62. Friedman KG, Margossian R, Graham DA, Harrild DM, Emani SM, Wilkins-Haug LE, McElhinney DB, Tworetzky W. Postnatal left ventricular diastolic function after fetal aortic valvuloplasty. Am J Cardiol. 2011 Aug 15; 108(4):556-60. View abstract
  63. Oepkes D, Moon-Grady AJ, Wilkins-Haug L, Tworetzky W, Arzt W, Devlieger R. 2010 Report from the ISPD Special Interest Group fetal therapy: fetal cardiac interventions. Prenat Diagn. 2011 Mar; 31(3):249-51. View abstract
  64. Vogel M, McElhinney DB, Wilkins-Haug LE, Marshall AC, Benson CB, Juraszek AL, Silva V, Lock JE, Marx GR, Tworetzky W. Aortic stenosis and severe mitral regurgitation in the fetus resulting in giant left atrium and hydrops: pathophysiology, outcomes, and preliminary experience with pre-natal cardiac intervention. J Am Coll Cardiol. 2011 Jan 18; 57(3):348-55. View abstract
  65. Edlow AG, Reiss R, Benson CB, Gerrol P, Wilkins-Haug L. Monochorionic diamniotic twin gestations discordant for markedly enlarged nuchal translucency. Prenat Diagn. 2011 Mar; 31(3):299-306. View abstract
  66. McElhinney DB, Vogel M, Benson CB, Marshall AC, Wilkins-Haug LE, Silva V, Tworetzky W. Assessment of left ventricular endocardial fibroelastosis in fetuses with aortic stenosis and evolving hypoplastic left heart syndrome. Am J Cardiol. 2010 Dec 15; 106(12):1792-7. View abstract
  67. Smith NA, Wilkins-Haug L, Santolaya-Forgas J, Acker D, Economy KE, Benson CB, Robinson JN. Contemporary management of monochorionic diamniotic twins: outcomes and delivery recommendations revisited. Am J Obstet Gynecol. 2010 Aug; 203(2):133.e1-6. View abstract
  68. McElhinney DB, Benson CB, Brown DW, Wilkins-Haug LE, Marshall AC, Zaccagnini L, Tworetzky W. Cerebral blood flow characteristics and biometry in fetuses undergoing prenatal intervention for aortic stenosis with evolving hypoplastic left heart syndrome. Ultrasound Med Biol. 2010 Jan; 36(1):29-37. View abstract
  69. Vogel M, Wilkins-Haug LE, McElhinney DB, Marshall AC, Benson CB, Silva V, Tworetzky W. Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. Fetal Diagn Ther. 2010; 27(1):40-5. View abstract
  70. Kleeman L, Bianchi DW, Shaffer LG, Rorem E, Cowan J, Craigo SD, Tighiouart H, Wilkins-Haug LE. Use of array comparative genomic hybridization for prenatal diagnosis of fetuses with sonographic anomalies and normal metaphase karyotype. Prenat Diagn. 2009 Dec; 29(13):1213-7. View abstract
  71. Steigman SA, Kunisaki SM, Wilkins-Haug L, Takoudes TC, Fauza DO. Optical properties of human amniotic fluid: implications for videofetoscopic surgery. Fetal Diagn Ther. 2010; 27(2):87-90. View abstract
  72. McElhinney DB, Marshall AC, Wilkins-Haug LE, Brown DW, Benson CB, Silva V, Marx GR, Mizrahi-Arnaud A, Lock JE, Tworetzky W. Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndrome. Circulation. 2009 Oct 13; 120(15):1482-90. View abstract
  73. Tworetzky W, McElhinney DB, Marx GR, Benson CB, Brusseau R, Morash D, Wilkins-Haug LE, Lock JE, Marshall AC. In utero valvuloplasty for pulmonary atresia with hypoplastic right ventricle: techniques and outcomes. Pediatrics. 2009 Sep; 124(3):e510-8. View abstract
  74. Porter A, Benson CB, Hawley P, Wilkins-Haug L. Outcome of fetuses with a prenatal ultrasound diagnosis of isolated omphalocele. Prenat Diagn. 2009 Jul; 29(7):668-73. View abstract
  75. Wilkins-Haug L. Epigenetics and assisted reproduction. Curr Opin Obstet Gynecol. 2009 Jun; 21(3):201-6. View abstract
  76. Turner CG, Tworetzky W, Wilkins-Haug LE, Jennings RW. Cardiac anomalies in the fetus. Clin Perinatol. 2009 Jun; 36(2):439-49, xi. View abstract
  77. Wilkins-Haug L, Porter A, Hawley P, Benson CB. Isolated fetal omphalocele, Beckwith-Wiedemann syndrome, and assisted reproductive technologies. Birth Defects Res A Clin Mol Teratol. 2009 Jan; 85(1):58-62. View abstract
  78. Marshall AC, Levine J, Morash D, Silva V, Lock JE, Benson CB, Wilkins-Haug LE, McElhinney DB, Tworetzky W. Results of in utero atrial septoplasty in fetuses with hypoplastic left heart syndrome. Prenat Diagn. 2008 Nov; 28(11):1023-8. View abstract
  79. Wilkins-Haug L. Assisted reproductive technology, congenital malformations, and epigenetic disease. Clin Obstet Gynecol. 2008 Mar; 51(1):96-105. View abstract
  80. Selamet Tierney ES, Wald RM, McElhinney DB, Marshall AC, Benson CB, Colan SD, Marcus EN, Marx GR, Levine JC, Wilkins-Haug L, Lock JE, Tworetzky W. Changes in left heart hemodynamics after technically successful in-utero aortic valvuloplasty. Ultrasound Obstet Gynecol. 2007 Oct; 30(5):715-20. View abstract
  81. Mizrahi-Arnaud A, Tworetzky W, Bulich LA, Wilkins-Haug LE, Marshall AC, Benson CB, Lock JE, McElhinney DB. Pathophysiology, management, and outcomes of fetal hemodynamic instability during prenatal cardiac intervention. Pediatr Res. 2007 Sep; 62(3):325-30. View abstract
  82. Weksberg R, Shuman C, Wilkins-Haug L, Mann M, Croughan M, Stewart D, Rakowsky C, Leader A, Hall J, Friedman JM, Simpson JL, Holmes L, Infante-Rivard C. Workshop report: evaluation of genetic and epigenetic risks associated with assisted reproductive technologies and infertility. Fertil Steril. 2007 Jul; 88(1):27-31. View abstract
  83. Kunisaki SM, Fauza DO, Barnewolt CE, Estroff JA, Myers LB, Bulich LA, Wong G, Levine D, Wilkins-Haug LE, Benson CB, Jennings RW. Ex utero intrapartum treatment with placement on extracorporeal membrane oxygenation for fetal thoracic masses. J Pediatr Surg. 2007 Feb; 42(2):420-5. View abstract
  84. Kunisaki SM, Barnewolt CE, Estroff JA, Myers LB, Fauza DO, Wilkins-Haug LE, Grable IA, Ringer SA, Benson CB, Nemes LP, Morash D, Buchmiller TL, Wilson JM, Jennings RW. Ex utero intrapartum treatment with extracorporeal membrane oxygenation for severe congenital diaphragmatic hernia. J Pediatr Surg. 2007 Jan; 42(1):98-104; discussion 104-6. View abstract
  85. Chang G, McNamara TK, Wilkins-Haug L, Orav EJ. Estimates of prenatal abstinence from alcohol: a matter of perspective. Addict Behav. 2007 Aug; 32(8):1593-601. View abstract
  86. Chang G, McNamara T, Wilkins-Haug L, Orav EJ. Stages of change and prenatal alcohol use. J Subst Abuse Treat. 2007 Jan; 32(1):105-9. View abstract
  87. Chang G, McNamara TK, Orav EJ, Wilkins-Haug L. Brief intervention for prenatal alcohol use: the role of drinking goal selection. J Subst Abuse Treat. 2006 Dec; 31(4):419-24. View abstract
  88. Wilkins-Haug LE, Tworetzky W, Benson CB, Marshall AC, Jennings RW, Lock JE. Factors affecting technical success of fetal aortic valve dilation. Ultrasound Obstet Gynecol. 2006 Jul; 28(1):47-52. View abstract
  89. Chang G, McNamara T, Orav EJ, Wilkins-Haug L. Identifying risk drinking in expectant fathers. Birth. 2006 Jun; 33(2):110-6. View abstract
  90. Wilkins-Haug L, Quade B, Morton CC. Confined placental mosaicism as a risk factor among newborns with fetal growth restriction. Prenat Diagn. 2006 May; 26(5):428-32. View abstract
  91. Chang G, McNamara TK, Orav EJ, Wilkins-Haug L. Alcohol use by pregnant women: partners, knowledge, and other predictors. J Stud Alcohol. 2006 Mar; 67(2):245-51. View abstract
  92. Browning MF, Levy HL, Wilkins-Haug LE, Larson C, Shih VE. Fetal fatty acid oxidation defects and maternal liver disease in pregnancy. Obstet Gynecol. 2006 Jan; 107(1):115-20. View abstract
  93. McNamara TK, Orav EJ, Wilkins-Haug L, Chang G. Social support and prenatal alcohol use. J Womens Health (Larchmt). 2006 Jan-Feb; 15(1):70-6. View abstract
  94. McNamara TK, Orav EJ, Wilkins-Haug L, Chang G. Risk during pregnancy--self-report versus medical record. Am J Obstet Gynecol. 2005 Dec; 193(6):1981-5. View abstract
  95. Marshall AC, Tworetzky W, Bergersen L, McElhinney DB, Benson CB, Jennings RW, Wilkins-Haug LE, Marx GR, Lock JE. Aortic valvuloplasty in the fetus: technical characteristics of successful balloon dilation. J Pediatr. 2005 Oct; 147(4):535-9. View abstract
  96. Wilkins-Haug LE, Benson CB, Tworetzky W, Marshall AC, Jennings RW, Lock JE. In-utero intervention for hypoplastic left heart syndrome--a perinatologist's perspective. Ultrasound Obstet Gynecol. 2005 Oct; 26(5):481-6. View abstract
  97. Chang G, McNamara TK, Orav EJ, Koby D, Lavigne A, Ludman B, Vincitorio NA, Wilkins-Haug L. Brief intervention for prenatal alcohol use: a randomized trial. Obstet Gynecol. 2005 May; 105(5 Pt 1):991-8. View abstract
  98. Rahbar R, Vogel A, Myers LB, Bulich LA, Wilkins-Haug L, Benson CB, Grable IA, Levine D, Fishman SJ, Jennings RW, Estroff JA, Barnewolt CE. Fetal surgery in otolaryngology: a new era in the diagnosis and management of fetal airway obstruction because of advances in prenatal imaging. Arch Otolaryngol Head Neck Surg. 2005 May; 131(5):393-8. View abstract
  99. Tworetzky W, Wilkins-Haug L, Jennings RW, van der Velde ME, Marshall AC, Marx GR, Colan SD, Benson CB, Lock JE, Perry SB. Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of successful intervention. Circulation. 2004 Oct 12; 110(15):2125-31. View abstract
  100. Falk SJ, Campbell LJ, Lee-Parritz A, Cohen AP, Ecker J, Wilkins-Haug L, Lieberman E. Expectant management in spontaneous preterm premature rupture of membranes between 14 and 24 weeks' gestation. J Perinatol. 2004 Oct; 24(10):611-6. View abstract
  101. Marshall AC, van der Velde ME, Tworetzky W, Gomez CA, Wilkins-Haug L, Benson CB, Jennings RW, Lock JE. Creation of an atrial septal defect in utero for fetuses with hypoplastic left heart syndrome and intact or highly restrictive atrial septum. Circulation. 2004 Jul 20; 110(3):253-8. View abstract
  102. Doubilet PM, Benson CB, Wilkins-Haug L, Ringer S. Fetuses subsequently born premature are smaller than gestational age-matched fetuses not born premature. J Ultrasound Med. 2003 Apr; 22(4):359-63. View abstract
  103. Li M, Shuman C, Fei YL, Cutiongco E, Bender HA, Stevens C, Wilkins-Haug L, Day-Salvatore D, Yong SL, Geraghty MT, Squire J, Weksberg R. GPC3 mutation analysis in a spectrum of patients with overgrowth expands the phenotype of Simpson-Golabi-Behmel syndrome. Am J Med Genet. 2001 Aug 01; 102(2):161-8. View abstract
  104. Lee C, Murray MF, Miron PM, Marsden D, Irons M, Wilkins-Haug LE, Morton CC. Clinical picture: Multicolour karyotyping. Lancet. 2001 Apr 21; 357(9264):1240. View abstract
  105. Jänne PA, Rodriguez-Thompson D, Metcalf DR, Swanson SJ, Greisman HA, Wilkins-Haug L, Johnson BE. Chemotherapy for a patient with advanced non-small-cell lung cancer during pregnancy: a case report and a review of chemotherapy treatment during pregnancy. Oncology. 2001; 61(3):175-83. View abstract
  106. Wilkins-Haug L, Erickson K, Hill L, Power M, Holzman GB, Schulkin J. Obstetrician-gynecologists' opinions and attitudes on the role of genetics in women's health. J Womens Health Gend Based Med. 2000 Oct; 9(8):873-9. View abstract
  107. Norwitz ER, Hoyte LP, Jenkins KJ, van der Velde ME, Ratiu P, Rodriguez-Thompson D, Wilkins-Haug L, Tempany CM, Fishman SJ. Separation of conjoined twins with the twin reversed-arterial-perfusion sequence after prenatal planning with three-dimensional modeling. N Engl J Med. 2000 Aug 10; 343(6):399-402. View abstract
  108. Chang G, Goetz MA, Wilkins-Haug L, Berman S. A brief intervention for prenatal alcohol use: an in-depth look. J Subst Abuse Treat. 2000 Jun; 18(4):365-9. View abstract
  109. Wilkins-Haug L, Hill LD, Power ML, Holzman GB, Schulkin J. Gynecologists' training, knowledge, and experiences in genetics: a survey. Obstet Gynecol. 2000 Mar; 95(3):421-4. View abstract
  110. Chang G, Wilkins-Haug L, Berman S, Goetz MA. Brief intervention for alcohol use in pregnancy: a randomized trial. Addiction. 1999 Oct; 94(10):1499-508. View abstract
  111. Chang G, Goetz MA, Wilkins-Haug L, Berman S. Prenatal alcohol consumption. Self versus collateral report. J Subst Abuse Treat. 1999 Jul-Sep; 17(1-2):85-9. View abstract
  112. Wilkins-Haug L. Considerations for delivery of infants with congenital abnormalities. Obstet Gynecol Clin North Am. 1999 Jun; 26(2):399-412, vii. View abstract
  113. Wilkins-Haug L, Hill L, Schmidt L, Holzman GB, Schulkin J. Genetics in obstetricians' offices: a survey study. Obstet Gynecol. 1999 May; 93(5 Pt 1):642-7. View abstract
  114. Chang G, Wilkins-Haug L, Berman S, Goetz MA. The TWEAK: application in a prenatal setting. J Stud Alcohol. 1999 May; 60(3):306-9. View abstract
  115. Chang G, Goetz MA, Wilkins-Haug L, Berman S. Identifying prenatal alcohol use: screening instruments versus clinical predictors. Am J Addict. 1999; 8(2):87-93. View abstract
  116. Wilkins-Haug L. Unexplained elevated maternal serum alpha-fetoprotein: what is the appropriate follow-up? Curr Opin Obstet Gynecol. 1998 Dec; 10(6):469-74. View abstract
  117. Chang G, Wilkins-Haug L, Berman S, Goetz MA, Behr H, Hiley A. Alcohol use and pregnancy: improving identification. Obstet Gynecol. 1998 Jun; 91(6):892-8. View abstract
  118. Chang G, Wilkins-Haug L, Berman S, Goetz MA. Pregnant women with negative alcohol screens do drink less. A prospective study. Am J Addict. 1998; 7(4):299-304. View abstract
  119. Nadel AS, Norton ME, Wilkins-Haug L. Cost-effectiveness of strategies used in the evaluation of pregnancies complicated by elevated maternal serum alpha-fetoprotein levels. Obstet Gynecol. 1997 May; 89(5 Pt 1):660-5. View abstract
  120. Wilkins-Haug LE, Rein MS, Hornstein MD. Oligospermic men: the role of karyotype analysis prior to intracytoplasmic sperm injection. Fertil Steril. 1997 Apr; 67(4):612-4. View abstract
  121. Shipp TD, Wilkins-Haug L. The association of early-onset fetal growth restriction, elevated maternal serum alpha-fetoprotein, and the development of severe pre-eclampsia. Prenat Diagn. 1997 Apr; 17(4):305-9. View abstract
  122. Wilkins-Haug LE, Doubilet P. Successful thoracoamniotic shunting and review of the literature in unilateral pleural effusion with hydrops. J Ultrasound Med. 1997 Feb; 16(2):153-60. View abstract
  123. Wilkins-Haug L. Teratogen update: toluene. Teratology. 1997 Feb; 55(2):145-51. View abstract
  124. Wilkins-Haug L, Horton JA, Cruess DF, Frigoletto FD. Antepartum screening in the office-based practice: findings from the collaborative Ambulatory Research Network. Obstet Gynecol. 1996 Oct; 88(4 Pt 1):483-9. View abstract
  125. Wilkins-Haug LE, Sandstrom MM, Weremowicz S. Fluorescence in situ hybridization for the detection of aneuploidy from archived fetal cells. Obstet Gynecol. 1996 Oct; 88(4 Pt 2):684-7. View abstract
  126. Hillstrom MM, Brown DL, Wilkins-Haug L, Genest DR. Sonographic appearance of placental villous hydrops associated with Beckwith-Wiedemann syndrome. J Ultrasound Med. 1995 Jan; 14(1):61-4. View abstract
  127. Wilkins-Haug L, Roberts DJ, Morton CC. Confined placental mosaicism and intrauterine growth retardation: a case-control analysis of placentas at delivery. Am J Obstet Gynecol. 1995 Jan; 172(1 Pt 1):44-50. View abstract
  128. Arnold GL, Kirby RS, Langendoerfer S, Wilkins-Haug L. Toluene embryopathy: clinical delineation and developmental follow-up. Pediatrics. 1994 Feb; 93(2):216-20. View abstract
  129. Bianchi DW, Wilkins-Haug LE, Enders AC, Hay ED. Origin of extraembryonic mesoderm in experimental animals: relevance to chorionic mosaicism in humans. Am J Med Genet. 1993 Jun 15; 46(5):542-50. View abstract
  130. Wilkins-Haug L. The emerging genetic theories of unstable DNA, uniparental disomy, and imprinting. Curr Opin Obstet Gynecol. 1993 Apr; 5(2):179-85. View abstract
  131. Wilkins-Haug L, Freedman W. Progression of exencephaly to anencephaly in the human fetus--an ultrasound perspective. Prenat Diagn. 1991 Apr; 11(4):227-33. View abstract
  132. Wilkins-Haug L, Gabow PA. Toluene abuse during pregnancy: obstetric complications and perinatal outcomes. Obstet Gynecol. 1991 Apr; 77(4):504-9. View abstract