EDUCATION

Medical School

MB BCh
  • University of Witwatersrand Medical School , 1984 , Johannesburg , South Africa

Internship

General Surgery/Internal Medicine
  • Johannesburg Hospital (now The Charlotte Maxeke Johannesburg Academic Hospital) , 1985 , Johannesburg , South Africa

Residency

Anesthesiology
  • Johannesburg Hospital (now The Charlotte Maxeke Johannesburg Academic Hospital) , 1989 , Johannesburg , South Africa

Residency

Anesthesiology
  • Groote Schuur Hospital , 1993 , Cape Town , South Africa

Fellowship

Pediatric Anesthesia
  • Boston Children’s Hospital , 1995 , Boston , MA

Fellowship

Cardiac Anesthesia
  • Boston Children’s Hospital/Beth Israel Deaconess Medical Center , 1996 , Boston , MA

CERTIFICATIONS

  • American Board of Anesthesiology
  • American Board of Anesthesiology, Pediatric Anesthesiology

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. NIRS measures in pain and analgesia: Fundamentals, features, and function. Neurosci Biobehav Rev. 2021 Jan; 120:335-353. View abstract
  2. Sensitivity of a Next-Generation NIRS Device to Detect Low Mixed Venous Oxyhemoglobin Saturations in the Single Ventricle Population. Anesth Analg. 2020 09; 131(3):e138-e141. View abstract
  3. Near-Infrared Spectroscopy in Pediatric Congenital Heart Disease. J Cardiothorac Vasc Anesth. 2020 Feb; 34(2):489-500. View abstract
  4. A Time-Frequency Approach for Cerebral Embolic Load Monitoring. IEEE Trans Biomed Eng. 2020 04; 67(4):1007-1018. View abstract
  5. Validation of a Second-Generation Near-Infrared Spectroscopy Monitor in Children With Congenital Heart Disease. Anesth Analg. 2019 04; 128(4):661-668. View abstract
  6. Selected 2017 Highlights in Congenital Cardiac Anesthesia. J Cardiothorac Vasc Anesth. 2018 08; 32(4):1546-1555. View abstract
  7. Cerebral Oxygen Saturation in Children With Congenital Heart Disease and Chronic Hypoxemia. Anesth Analg. 2017 07; 125(1):234-240. View abstract
  8. Cerebral near-infrared spectroscopy insensitively detects low cerebral venous oxygen saturations after stage 1 palliation. J Thorac Cardiovasc Surg. 2017 09; 154(3):1056-1062. View abstract
  9. Non-invasive Assessment of Cerebral Blood Flow and Oxygen Metabolism in Neonates during Hypothermic Cardiopulmonary Bypass: Feasibility and Clinical Implications. Sci Rep. 2017 03 09; 7:44117. View abstract
  10. Anesthesia, brain changes, and behavior: Insights from neural systems biology. Prog Neurobiol. 2017 06; 153:121-160. View abstract
  11. Cerebral High-Intensity Transient Signals during Pediatric Cardiac Catheterization: A Pilot Study Using Transcranial Doppler Ultrasonography. J Neuroimaging. 2017 07; 27(4):381-387. View abstract
  12. White Matter Volume Predicts Language Development in Congenital Heart Disease. J Pediatr. 2017 02; 181:42-48.e2. View abstract
  13. Noninvasive Cardiac Output Estimation by Inert Gas Rebreathing in Mechanically Ventilated Pediatric Patients. J Pediatr. 2016 10; 177:184-190.e3. View abstract
  14. Capturing Pain in the Cortex during General Anesthesia: Near Infrared Spectroscopy Measures in Patients Undergoing Catheter Ablation of Arrhythmias. PLoS One. 2016; 11(7):e0158975. View abstract
  15. Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy. Pain. 2016 Apr; 157(4):840-848. View abstract
  16. Reply to Letter: "Surgically Induced Neuropathic Pain: Understanding the Perioperative Process". Ann Surg. 2015 Jun; 261(6):e162-3. View abstract
  17. Evaluation of cerebral oxygenation and perfusion with conversion from an arterial-to-systemic shunt circulation to the bidirectional Glenn circulation in patients with univentricular cardiac abnormalities. J Cardiothorac Vasc Anesth. 2015 Feb; 29(1):95-100. View abstract
  18. Advances in the Care of Adults With Congenital Heart Disease. Semin Cardiothorac Vasc Anesth. 2015 Sep; 19(3):175-86. View abstract
  19. Cerebral blood flow velocity and neurodevelopmental outcome in infants undergoing surgery for congenital heart disease. Ann Thorac Surg. 2014 Jul; 98(1):125-32. View abstract
  20. Case 6-2013: Perioperative management of an adult patient with tetralogy of fallot and pheochromocytoma. J Cardiothorac Vasc Anesth. 2013 Dec; 27(6):1399-406. View abstract
  21. Surgically induced neuropathic pain: understanding the perioperative process. Ann Surg. 2013 Mar; 257(3):403-12. View abstract
  22. Massive air embolism in a Fontan patient. J Extra Corpor Technol. 2011 Jun; 43(2):79-83. View abstract
  23. 2010 meeting of the Congenital Cardiac Anesthesia Society (CCAS) and the Society for Pediatric Anesthesia (SPA). Anesth Analg. 2010 Nov; 111(5):1331-3. View abstract
  24. Pediatric heart transplantation: demographics, outcomes, and anesthetic implications. Paediatr Anaesth. 2011 May; 21(5):594-603. View abstract
  25. Anesthesia and perioperative stress: consequences on neural networks and postoperative behaviors. Prog Neurobiol. 2010 Dec; 92(4):601-12. View abstract
  26. Relationship of intraoperative cerebral oxygen saturation to neurodevelopmental outcome and brain magnetic resonance imaging at 1 year of age in infants undergoing biventricular repair. Circulation. 2010 Jul 20; 122(3):245-54. View abstract
  27. Subtle hemorrhagic brain injury is associated with neurodevelopmental impairment in infants with repaired congenital heart disease. J Thorac Cardiovasc Surg. 2009 Aug; 138(2):374-81. View abstract
  28. Cerebral oximetry during infant cardiac surgery: evaluation and relationship to early postoperative outcome. Anesth Analg. 2009 Apr; 108(4):1122-31. View abstract
  29. Congenital supravalvular aortic stenosis and sudden death associated with anesthesia: what's the mystery? Anesth Analg. 2008 Dec; 107(6):1848-54. View abstract
  30. Matrix-array 3-dimensional echocardiographic assessment of volumes, mass, and ejection fraction in young pediatric patients with a functional single ventricle: a comparison study with cardiac magnetic resonance. Circulation. 2008 Apr 08; 117(14):1842-8. View abstract
  31. Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery. J Thorac Cardiovasc Surg. 2008 Feb; 135(2):347-54, 354.e1-4. View abstract
  32. The frequency of anesthesia-related cardiac arrests in patients with congenital heart disease undergoing cardiac surgery. Anesth Analg. 2007 Aug; 105(2):335-43. View abstract
  33. Cerebral perfusion and oxygenation after the Norwood procedure: comparison of right ventricle-pulmonary artery conduit with modified Blalock-Taussig shunt. J Thorac Cardiovasc Surg. 2007 Mar; 133(3):648-55. View abstract
  34. Anesthetic management of pial synangiosis and intracranial hemorrhage with a Fontan circulation. Paediatr Anaesth. 2006 Jan; 16(1):72-6. View abstract
  35. Anesthetic management of the neonate with congenital complete heart block: a 16-year review. Paediatr Anaesth. 2005 Dec; 15(12):1059-66. View abstract
  36. An evaluation of bilateral monitoring of cerebral oxygen saturation during pediatric cardiac surgery. Anesth Analg. 2005 Nov; 101(5):1294-300. View abstract
  37. Hemodynamic responses to etomidate on induction of anesthesia in pediatric patients. Anesth Analg. 2005 Sep; 101(3):645-50, table of contents. View abstract
  38. Evaluation of plasma fentanyl concentrations in infants during cardiopulmonary bypass with low-volume circuits. J Cardiothorac Vasc Anesth. 2005 Jun; 19(3):316-21. View abstract
  39. Iatrogenic hyperthermia during cardiac magnetic resonance imaging. Anesth Analg. 2004 Oct; 99(4):1053-5, table of contents. View abstract
  40. Cardiovascular causes of airway compression. Paediatr Anaesth. 2004 Jan; 14(1):60-74. View abstract
  41. Anesthetic implications of primary cardiac tumors in infants and children. J Cardiothorac Vasc Anesth. 2002 Oct; 16(5):582-6. View abstract
  42. Bispectral index monitoring during infant cardiac surgery: relationship of BIS to the stress response and plasma fentanyl levels. Paediatr Anaesth. 2001 Nov; 11(6):663-9. View abstract
  43. Severe hypercarbia during cardiopulmonary bypass: a complication of CO2 flooding of the surgical field. Anesth Analg. 1998 Feb; 86(2):264-6. View abstract
  44. Pethidine-associated seizure in a healthy adolescent receiving pethidine for postoperative pain control. Paediatr Anaesth. 1998; 8(4):349-52. View abstract
  45. Administration of magnesium sulphate before rocuronium: effects on speed of onset and duration of neuromuscular block. Br J Anaesth. 1997 Jul; 79(1):122-4. View abstract
  46. Chylous ascites following abdominal aortic surgery. S Afr J Surg. 1995 Mar; 33(1):26-8. View abstract
  47. Acetazolamide in the treatment of metabolic alkalosis in critically ill patients. Heart Lung. 1991 Sep; 20(5 Pt 1):455-9. View abstract