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Endometriosis | Overview

What is endometriosis?

A teen girl or woman has endometriosis when the endometrium, the tissue that normally lines her uterus, grows in other places, such as the fallopian tubes, ovaries, or pelvic tissue. This misplaced tissue can cause serious pelvic pain or painful menstrual periods (dysmenorrhea).

When endometrium grows in other places, it functions like it does in the uterus by thickening, breaking down, and bleeding away each month. Since there is nowhere for this blood to go, it stays trapped in the body, and this can cause painful cysts and scar tissue. Endometriosis affects an estimated 5.5 million teen girls and women in North America.

Without treatment, endometriosis can lead to infertility. Thirty to 40 percent of women with endometriosis are infertile. However, there are successful fertility treatments for women with newly discovered endometriosis, and early treatment during adolescence can prevent infertility.

What are the symptoms of endometriosis?

Endometriosis can be mild, moderate, or severe. Some teen girls or women experience no symptoms at all, but it tends to get worse over time. If you or your daughter has endometriosis, you could be experiencing:

Painful periods (dysmenorrhea)

  • Pelvic pain may include lower back and abdominal pain.
  • The level of pain may not match the severity of the endometriosis.
  • Some teen girls or women have mild endometriosis and severe pain, while others have more severe endometriosis and little pain.

Chronic pelvic pain

  • Pain may be accompanied by frequent urination, diarrhea, or constipation.
  • excessive bleeding or bleeding between periods

Infertility

Endometriosis can cause scar tissue that can make it hard for a woman to get pregnant or cause infertility. Sometimes endometriosis is only diagnosed when a woman is seeking infertility treatment.

What causes endometriosis?

The exact cause of endometriosis is unknown, although we do know that it runs in families. The three most accepted theories of endometriosis are:

  • Sampson's Theory: Menstrual blood filled with endometrial cells flows backward through the fallopian tubes and attaches to other surfaces outside the uterus.
  • Meyer's Theory: Cells with the potential to become endometrial cells are present in the abdomen at birth, but don't change into endometrial cells until later in a woman's life.
  • Vascular Theory: The endometrial tissue travels through the blood vessels to other tissues. It implants and grows, just as metastasizing cancer cells do. (Endometrial cells have no more chance of becoming cancerous than any other cell.)

How we care for endometriosis

The Division of Gynecology at Boston Children's Hospital provides expert medical care, special health education programs, and a wealth of information to young women who are living with endometriosis. Pelvic pain and painful menstruation can be distressing for teens. We provide age-appropriate treatment, counseling, and special health education programs, including supervised online chats.

Endometriosis | Overview

What is endometriosis?

A woman has endometriosis when the tissue that normally lines her uterus, the endometrium, grows in other places, such as the fallopian tubes, ovaries or pelvic tissue. This misplaced tissue can cause serious pelvic pain or painful menstrual periods.

When endometrium, the normal lining of the uterus, grows in other places, it continues its normal menstrual duties of thickening, breaking down and bleeding away each month. Since there is nowhere for this blood to go, it stays trapped in the body, and this can cause painful cysts and scar tissue. Endometriosis affects an estimated 5.5 million women in North America. 

Without treatment, endometriosis can lead to infertility. Thirty to 40 percent of women with endometriosis are infertile. Adolescents can be treated so they so don't develop infertility.

How we care for endometriosis

The Center for Young Women's Health, part of the Gynecology Program at Boston Children's Hospital, provides expert medical care, special health education programs and a wealth of information to young women who may be dealing with endometriosis. Pelvic pain and painful menstruation can be distressing for teens, and the Center provides counseling and special health education programs, including supervised online chats.

Endometriosis | Symptoms and Causes

What are the symptoms of endometriosis?

Endometriosis can be mild, moderate or severe. Some women experience no symptoms at all, but it tends to get worse over time. If your daughter has endometriosis, she could be experiencing:

Painful periods (dysmennorhea)

  • Pelvic pain may include lower back and abdominal pain.
  • The level of pain may not match the severity of the endometriosis.
  • Some women have mild endometriosis and severe pain, while others have a lot of endometriosis and little pain.

Chronic pelvic pain

  • Pain may be accompanied by frequent urination, diarrhea or constipation.
  • excessive bleeding or bleeding between periods

Infertility

Sometimes endometriosis is only diagnosed when a women is seeking infertility treatment.

What causes endometriosis?

The exact cause of endometriosis is unknown, although we do know that it runs in families. The three most accepted theories of endometriosis are:

  • Sampson's Theory: Menstrual blood filled with endometrial cells flows backward through the fallopian tubes and attaches to other surfaces outside the uterus.
  • Meyer's Theory: Cells with the potential to become endometrial cells are present in the abdomen at birth, but don't change into endometrial cells until later in a woman's life.
  • Vascular Theory: The endometrial tissue travels through the blood vessels to other tissues. It implants and grows, just as metastasizing cancer cells do. (Endometrial cells have no more chance of becoming cancerous than any other cell.)

Endometriosis can lead to infertility, and 30 to 40 percent of women with endometriosis are infertile. However, there are successful fertility treatments for women with newly discovered endometriosis, and early treatment during adolescence can prevent infertility.

Endometriosis | Diagnosis and Treatment

How is endometriosis diagnosed?

There are no x-rays or blood tests to diagnose endometriosis. The only way to diagnose the condition is to have a procedure called a laparoscopy. This surgical procedure allows a doctor to look at the pelvic organs with a tiny camera. Other tests that your physician may order before the laparoscopy include:

  • blood tests or vaginal cultures (to check for infection)
  • a pelvic ultrasound or MRI (to rule out other conditions)

What is the treatment for endometriosis?

Hormonal treatments

Hormonal treatment such as birth control pills taken continuously can relieve symptoms in many patients. A gonadotropin-releasing hormone agonist (Gn-RHa), such as Lupron-Depot®, works by shutting off hormones made by the ovaries and temporarily stopping your period. It lowers the body's estrogen level and causes the endometriosis to shrink. This medicine has been approved by the U.S. Food and Drug Administration to be used for six months at a time. If used for over six months, studies have found it can cause changes in bone density. When GnR-Ha therapy is needed for longer than six months, it is used with another therapy to protect your bones.

Danazol is a drug that blocks the production of ovarian-stimulating hormones, preventing menstruation and the symptoms of endometriosis. However, danazol can cause unwanted side effects, such as acne and facial hair. Medroxyprogesterone (Depo-Provera) is an injectable drug that stops menstruation and the growth of endometrial implants. It stops the pain of endometriosis, but it may also lead to weight gain, decreased bone production, and depressed mood.

Aromatase inhibitors are agents used to treat breast cancer and endometriosis. They work by blocking the production of estrogen, which deprives the endometrial cells the estrogen they need to grow.

Surgery

During a laparoscopy, a physician destroys the visible endometriosis. Many teens find relief from the symptoms after this procedure, but some find the pain returns over time. Pain treatment services, such as biofeedback or physical therapy, may be used. Hysterectomy is not a recommended option in adolescents and is a last resort for women who no longer desire children and have failed treatments.

Endometriosis | Programs & Services