Neurogenic Bladder Pediatric Research and Clinical Trials

Boston Children's Hospital is continually working toward faster, more accurate diagnoses and more effective treatments for children with urologic disorders. Recent areas of research that our Department of Urology has conducted that hold promise for improving the lives of children with neurogenic bladder include: 

  • Tissue engineering: Typically, surgeons use a patient’s intestinal tissue to enlarge the bladder. However, the incompatibility of intestinal tissue and bladder tissue can lead to complications. At Children’s, we’ve pioneered innovations in engineering tissue (growing tissue in the laboratory using the patients’ own cells).
    • Using special techniques, our doctors can grow enough of the patient’s own bladder tissue to enlarge or replace the bladder. 
    • The world’s first recipients of tissue augments to enlarge the bladder were at Children’s. 
  • Stem cell research: In conjunction with the Harvard Stem Cell Institute, we are testing the use of embryonic stem cells and induced pluripotent stem (iPS) cells to augment bladder tissue, as well as the use of novel materials, like silk.

Read more about our Department of Urology.