Metopic Synostosis (Trigonocephaly) Pediatric Research and Clinical Trials

Research & Innovation

At Boston Children’s Hospital, our care is informed by our research, and our discoveries in the laboratory strengthen the care we provide at each child's bedside. In fact, Boston Children’s scientific research program is one of the largest and most active of any pediatric hospital in the world.

Among our research efforts with promise for treating metopic synostosis and other types of craniosynostosis are:

  • Mark Proctor, MD, Boston Children’s neurosurgeon, has authored several key papers about endoscopic approaches to the treatment of craniosynostosis. In addition, he was the lead neurosurgeon involved in developing formal parameters of care for the condition.
  • John Meara, MD, DMD, MBA, Boston Children's plastic surgeon-in-chief, is analyzing the genetic, phenotypic, cognitive and behavioral aspects of craniosynostosis.
  • Bonnie Padwa, MD, PhD, Boston Children's oral surgeon-in-chief, is assessing facial growth patterns in children with several craniofacial anomaly types. 

Clinical trials

Boston Children’s is known for pioneering some of the most effective diagnostic tools, therapies and preventive approaches in pediatric medicine. A significant part of our success comes from our commitment to research—and to advancing the frontiers of mental health care by conducting clinical trials.

Boston Children’s coordinates hundreds of clinical trials at any given time. Clinical trials are studies that may involve:

  • evaluating the effectiveness of a new drug therapy
  • testing a new diagnostic procedure or device
  • examining a new treatment method for a particular condition
  • taking a closer look at the causes and progression of specific diseases

While children must meet strict criteria in order to be eligible for a clinical trial, your child may be eligible to take part in a study. Before considering this option, you should be sure to:

  • consult with your child’s treating physician and treatment team
  • gather as much information as possible about the specific course of action outlined in the trial
  • do your own research about the latest breakthroughs relating to your child’s condition

If your physician recommends that your child participate in a clinical trial, you can feel confident that the plan detailed for that study represents the best and most innovative care available. Taking part in a clinical trial at Boston Children’s is entirely voluntary. Our team will be sure to fully address any questions you may have, and you may remove your child from the medical study at any time.