Current Environment:

Research Overview

Dr. Sung Chun studies computational and statistical genetics of rare and complex pulmonary disorders. His focus is in developing polygenic risk prediction algorithms and genetic colocalization tests to study the genetic architecture of pulmonary genetic disorders.

 

Research Background

Dr. Sung Chun received PhD in Computational and Systems Biology at Washington University in St. Louis in 2012. He did postdoctoral training in Genetics in Dr. Shamil Sunyaev's laboratory, Brigham and Women's Hospital/Harvard Medical School. He has been an Instructor at Harvard Medical School since 2015. In 2019 he joined the Division of Pulmonary Medicine at BCH.

Selected Publications

  1. Chun and Imakaev et al. (2018) Non-parametric polygenic risk prediction using partitioned GWAS summary statistics. (preprint).
  2. Chun et al. (2017) Limited statistical evidence for shared genetic effects of eQTLs and autoimmune disease-associated loci in three major immune cell types. Nat Genet. 2017 Apr; 49(4): 600–605.
  3. Savova, Chun and Sohail et al. (2016) Genes with monoallelic expression contribute disproportionately to genetic diversity in humans. Nat Genet. 2016 Mar; 48(3): 231–237.
  4. Chun and Fay. (2011) Evidence for Hitchhiking of Deleterious Mutations within the Human Genome. PLoS Genet. 2011 Aug; 7(8): e1002240.
  5. Chun and Fay. (2009) Identification of deleterious mutations within three human genomes. Genome Res. 2009 Sep; 19(9): 1553–1561.

Publications