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Researcher | Research Overview

Research in the Koehler Lab focuses on using human organoid systems as a platform to model congenital diseases and develop novel therapies for the inner ear and various craniofacial tissues, including the skin and facial bones.


Researcher | Research Background

Dr. Koehler received his doctorate in medical neuroscience and postdoctoral training from the Indiana University School of Medicine in the lab of Dr. Eri Hashino. His early work focused on neurodevelopment and generating inner ear organs from stem cells. Dr. Koehler became an Assistant Professor in 2015 and was named the Philip F. Holton Scholar in Otology in 2018 by the Department of Otolaryngology-Head and Neck Surgery at Indiana University School of Medicine. His lab pioneered methods for inducing human inner ear and skin tissue from pluripotent stem cells. He joined Boston Children's Hospital and the faculty in the Department of Otolaryngology-Head and Neck Surgery at Harvard Medical School in 2019. He is a principal investigator in the F.M. Kirby Neurobiology Center and an affiliated PI of the BCH Stem Cell Program and the Harvard Stem Cell Institute. His work is funded primarily by the National Institute of Health and the Department of Defense.


Researcher | Publications