EDUCATION

Medical School

  • Istanbul University, Cerrahpasa Medical School , 2005 , Istanbul , Turkey

Internship

  • Boston Children's Hospital , 2011 , Boston , MA

Residency

  • Boston Children's Hospital , 2013 , Boston , MA

Fellowship

  • Boston Children's Hospital , 2016 , Boston , MA

CERTIFICATIONS

  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Pediatric Rheumatology

PUBLICATIONS

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  1. Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. JCI Insight. 2021 Sep 22; 6(18). View abstract
  2. Differences in rituximab use between pediatric rheumatologists and nephrologists for the treatment of refractory lupus nephritis and renal flare in childhood-onset SLE. Pediatr Rheumatol Online J. 2021 Aug 30; 19(1):137. View abstract
  3. Coronary artery aneurysms in children is not always Kawasaki disease: a case report on Takayasu arteritis. BMC Rheumatol. 2021 Aug 12; 5(1):27. View abstract
  4. A multidisciplinary assessment of pain in juvenile idiopathic arthritis. Semin Arthritis Rheum. 2021 08; 51(4):700-711. View abstract
  5. Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. J Clin Invest. 2020 11 02; 130(11):5942-5950. View abstract
  6. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. JCI Insight. 2020 03 26; 5(6). View abstract
  7. Serine/threonine phosphatase PP2A is essential for optimal B cell function. JCI Insight. 2020 03 12; 5(5). View abstract
  8. Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Ann Rheum Dis. 2020 02; 79(2):225-231. View abstract
  9. PP2A enables IL-2 signaling by preserving IL-2Rß chain expression during Treg development. JCI Insight. 2019 03 26; 5. View abstract
  10. Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective. Trends Mol Med. 2017 07; 23(7):615-635. View abstract
  11. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016 May; 17(5):556-64. View abstract
  12. TRIF signaling is essential for TLR4-driven IgE class switching. J Immunol. 2014 Mar 15; 192(6):2651-8. View abstract
  13. Toll-like receptor 9, transmembrane activator and calcium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B-cell activation. J Allergy Clin Immunol. 2011 Sep; 128(3):601-9.e1-4. View abstract
  14. Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16252-6. View abstract
  15. The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function. Blood. 2009 Sep 10; 114(11):2254-62. View abstract
  16. Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells. J Allergy Clin Immunol. 2009 Jun; 123(6):1277-86.e5. View abstract
  17. Primary immune deficiencies with aberrant IgE production. J Allergy Clin Immunol. 2008 Dec; 122(6):1054-62; quiz 1063-4. View abstract
  18. Transmembrane activator and calcium-modulator and cyclophilin ligand interactor mutations in common variable immunodeficiency. Curr Opin Allergy Clin Immunol. 2008 Dec; 8(6):520-6. View abstract
  19. Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation. J Allergy Clin Immunol. 2007 Oct; 120(4):885-91. View abstract