Hypospadias Pediatric Research and Clinical Trials

Research & Innovation

Beyond using the most-up-to-date technology to treat children with hypospadias, the Department of Urology at Boston Children’s Hospital is also looking to the future. Our physicians and researchers are leading a number of studies and trials that hold great promise in the detection and treatment of this condition. Their projects include:

  • conducting ongoing research into the genetics of hypospadias, to understand what causes it and help identify it at the earliest possible stage
  • developing techniques that allow surgeons to do more kinds of hypospadias operations in a single repair session, rather than two
  • working to reduce the incidence of fistulas, a complication sometimes seen after hypospadias surgery in which a small hole opens up in the newly formed urethra
  • developing expertise in using buccal mucosa—tissue from the inside of the cheek—for surgical grafts when no local tissue (that is, foreskin) is available

Clinical trials

There are many ways in which your child might benefit from Children’s medical research program. Our doctors and scientists have made many breakthrough discoveries about diseases like polio and leukemia; our ongoing innovative research continues to push the boundaries of the way pediatric medicine is practiced.

It’s possible that your child will be eligible to participate in one of Children’s current clinical trials. These studies are useful for a multitude of reasons: Some trials are designed to evaluate the effectiveness of a particular drug, treatment or therapy on a specific disease; others help doctors to better understand how and why certain conditions occur. At any given time, Children’s has hundreds of clinical trials under way.

And participation in any clinical trial is completely voluntary: We will take care to fully explain all elements of the treatment plan prior to the start of the trial, and you may remove your child from the medical study at any time.

Search current and upcoming clinical trials at Children’s.

Search the NIH’s list of clinical trials taking place around the world.