Peroral Endoscopic Myotomy (POEM)

Peroral endoscopic myotomy (POEM) is a type of endoscopic procedure used to treat esophageal achalasia — a disorder of the esophagus that makes swallowing difficult — in some older children and teens. Developed in 2008, it is the first widely adopted natural orifice endoscopic surgery. That means that it allows clinicians to access areas in the abdomen or chest through a naturally occurring orifice (opening), in this case, the mouth.

Esophageal achalasia is typically treated with a procedure called a thoracoscopic myotomy, a surgical procedure that cuts the lower esophageal sphincter, allowing food and liquids to pass to the stomach. POEM is a less-invasive way to perform the same repair with similar outcomes, shorter hospital stays and recovery times, and without skin incisions or surgical access points through the chest wall. For some types of esophageal achalasia, POEM has improved clinical results because it allows for treatment of a longer length of esophageal muscle above the sphincter.

Who is eligible for peroral endoscopic myotomy (POEM)?

Although POEM was originally developed for adult patients, it has since been used to treat esophageal achalasia in older children and teenagers, typically those over age 10. POEM isn’t currently suitable for younger children because the available equipment isn’t small enough for them. Your child’s clinician can help determine whether POEM is right for them.

What happens during peroral endoscopic myotomy (POEM)?

Your child will need to fast (no eating or drinking) for 12 hours prior to the POEM procedure. POEM is performed while your child is under anesthesia.

The doctor will pass an endoscope — a thin, flexible tube — through your child’s mouth and into their esophagus. The endoscope has a tiny camera that allows the doctor to see images from the esophagus on a video monitor.

Once inside the esophagus, the doctor will make a small incision in its lining. The endoscope is then advanced through the incision and a tunnel is created in the wall of the esophagus to the lower esophageal sphincter (the band of muscle that does not relax and open in patients with achalasia). This lower sphincter is then cut, which is called a myotomy.

At Boston Children’s Hospital, we perform an additional measurement of the pressures of the lower esophageal sphincter (called an Endoflip) before and after the sphincter is cut to ensure that the esophageal sphincter has been appropriately opened to improve swallowing.

After the sphincter is cut, the doctor will close the small incision at the opening of the tunnel with small clips, which come off on their own over the next couple weeks and pass through the GI tract.

Following POEM, your child will need to stay in the hospital overnight to recover. Their doctor will prescribe antibiotics to help prevent infection. The next day, your child will undergo a barium swallow test to confirm that the procedure was successful prior to resuming eating and returning home.

Peroral endoscopic myotomy (POEM) at Boston Children’s Hospital

Although POEM is increasingly used to treat esophageal achalasia in adults, Boston Children’s Hospital is one of just a few pediatric hospitals to offer POEM to teens and older children, and our pediatric gastroenterologist, Peter Ngo, MD, is the first specialist of his kind to successfully perform this procedure in the United States. He works closely with clinicians from the Motility and Functional Gastrointestinal Disorders Center and the Esophageal and Airway Treatment Center to provide exceptional care to patients eligible for POEM.