Current Environment: Production

Warning

Recall Alert

There is an antibacterial antibiotic recall. Read more

American Board of Pediatrics (Rheumatology) | Education

Undergraduate School

Amherst College

1989, Amherst, MA

Medical School

Harvard Medical School

Boston, MA

Internship

Massachusetts General Hospital

1996, Boston, MA

Residency

Massachusetts General Hospital

1999, Boston, MA

Fellowship

Brigham & Women's Hospital

2004, Boston, MA

Fellowship

Boston Children's Hospital

2006, Boston, MA

American Board of Pediatrics (Rheumatology) | Publications

  1. Sex Differences in B Cells From the Joints of Children With Oligoarticular Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2025 Mar 17. View Sex Differences in B Cells From the Joints of Children With Oligoarticular Juvenile Idiopathic Arthritis. Abstract

  2. Utility of Cytokine Biomarkers for the Diagnosis of Pediatric Pyogenic Musculoskeletal Infections. Open Forum Infect Dis. 2025 Apr; 12(4):ofaf139. View Utility of Cytokine Biomarkers for the Diagnosis of Pediatric Pyogenic Musculoskeletal Infections. Abstract

  3. The joint accumulation model of arthritis. Semin Arthritis Rheum. 2025 Jun; 72S:152685. View The joint accumulation model of arthritis. Abstract

  4. Early transcriptional effects of inflammatory cytokines reveal highly redundant cytokine networks. J Exp Med. 2025 Apr 07; 222(4). View Early transcriptional effects of inflammatory cytokines reveal highly redundant cytokine networks. Abstract

  5. A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis. bioRxiv. 2025 Jan 24. View A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis. Abstract

  6. Macrophage Activation Syndrome. Arthritis Rheumatol. 2025 Apr; 77(4):367-379. View Macrophage Activation Syndrome. Abstract

  7. The 'Treg paradox' in inflammatory arthritis. Nat Rev Rheumatol. 2025 Jan; 21(1):9-21. View The 'Treg paradox' in inflammatory arthritis. Abstract

  8. Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. J Allergy Clin Immunol. 2025 Apr; 155(4):1346-1356.e9. View Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. Abstract

  9. Sex-specific NLRP3 activation in neutrophils promotes neutrophil recruitment and NETosis in the murine model of diffuse alveolar hemorrhage. Front Immunol. 2024; 15:1466234. View Sex-specific NLRP3 activation in neutrophils promotes neutrophil recruitment and NETosis in the murine model of diffuse alveolar hemorrhage. Abstract

  10. EULAR/PReS recommendations for the diagnosis and management of Still's disease, comprising systemic juvenile idiopathic arthritis and adult-onset Still's disease. Ann Rheum Dis. 2024 Nov 14; 83(12):1614-1627. View EULAR/PReS recommendations for the diagnosis and management of Still's disease, comprising systemic juvenile idiopathic arthritis and adult-onset Still's disease. Abstract

  11. Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis. HGG Adv. 2025 Jan 09; 6(1):100375. View Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis. Abstract

  12. Regional specialization within the mammalian respiratory immune system. Trends Immunol. 2024 Nov; 45(11):871-891. View Regional specialization within the mammalian respiratory immune system. Abstract

  13. Classification Criteria for Axial Disease in Youth With Juvenile Spondyloarthritis. Arthritis Rheumatol. 2024 Dec; 76(12):1797-1808. View Classification Criteria for Axial Disease in Youth With Juvenile Spondyloarthritis. Abstract

  14. High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus. Nat Commun. 2024 Aug 09; 15(1):6804. View High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus. Abstract

  15. Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus. Semin Arthritis Rheum. 2024 Oct; 68:152516. View Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus. Abstract

  16. Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework. Pediatr Rheumatol Online J. 2024 Jul 10; 22(1):64. View Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework. Abstract

  17. Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis. medRxiv. 2024 May 09. View Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis. Abstract

  18. High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus. bioRxiv. 2024 Apr 12. View High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus. Abstract

  19. Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis. Nat Rev Rheumatol. 2024 May; 20(5):258-271. View Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis. Abstract

  20. "Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024. Arthritis Rheumatol. 2024 Jun; 76(6):819-822. View "Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024. Abstract

  21. Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development. Nat Commun. 2024 Mar 09; 15(1):2150. View Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development. Abstract

  22. Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant. Cell Genom. 2024 Feb 14; 4(2):100502. View Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant. Abstract

  23. Recent advances and evolving concepts in Still's disease. Nat Rev Rheumatol. 2024 Feb; 20(2):116-132. View Recent advances and evolving concepts in Still's disease. Abstract

  24. The 4th NextGen Therapies for SJIA and MAS: part 1 the elephant in the room: diagnostic/classification criteria for systemic juvenile idiopathic arthritis and adult-onset still's disease. Pediatr Rheumatol Online J. 2024 Jan 05; 21(Suppl 1):114. View The 4th NextGen Therapies for SJIA and MAS: part 1 the elephant in the room: diagnostic/classification criteria for systemic juvenile idiopathic arthritis and adult-onset still's disease. Abstract

  25. Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework. Res Sq. 2023 Dec 12. View Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework. Abstract

  26. Human and mouse neutrophils share core transcriptional programs in both homeostatic and inflamed contexts. Nat Commun. 2023 12 08; 14(1):8133. View Human and mouse neutrophils share core transcriptional programs in both homeostatic and inflamed contexts. Abstract

  27. Elevation of IL-17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders. Arthritis Rheumatol. 2024 02; 76(2):285-292. View Elevation of IL-17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders. Abstract

  28. Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. J Clin Invest. 2023 11 15; 133(22). View Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. Abstract

  29. Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant. Cell Genom. 2023 Nov 08; 3(11):100420. View Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant. Abstract

  30. Development of a Screening Algorithm for Lung Disease in Systemic Juvenile Idiopathic Arthritis. ACR Open Rheumatol. 2023 Oct; 5(10):556-562. View Development of a Screening Algorithm for Lung Disease in Systemic Juvenile Idiopathic Arthritis. Abstract

  31. NLRP3 is essential for neutrophil polarization and chemotaxis in response to leukotriene B4 gradient. Proc Natl Acad Sci U S A. 2023 08 29; 120(35):e2303814120. View NLRP3 is essential for neutrophil polarization and chemotaxis in response to leukotriene B4 gradient. Abstract

  32. Therapeutic Development in Polyarticular Course Juvenile Idiopathic Arthritis: Extrapolation, Dose Selection, and Clinical Trial Design. Arthritis Rheumatol. 2023 10; 75(10):1856-1866. View Therapeutic Development in Polyarticular Course Juvenile Idiopathic Arthritis: Extrapolation, Dose Selection, and Clinical Trial Design. Abstract

  33. Incidence and Risk Factors for Eosinophilia and Lung Disease in Biologic-Exposed Children With Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2023 10; 75(10):2063-2072. View Incidence and Risk Factors for Eosinophilia and Lung Disease in Biologic-Exposed Children With Systemic Juvenile Idiopathic Arthritis. Abstract

  34. Comparison of disease phenotypes and mechanistic insight on causal variants in patients with DADA2. J Allergy Clin Immunol. 2023 09; 152(3):771-782. View Comparison of disease phenotypes and mechanistic insight on causal variants in patients with DADA2. Abstract

  35. Biologics and JAK inhibitors for the treatment of monogenic systemic autoinflammatory diseases in children. J Allergy Clin Immunol. 2023 03; 151(3):607-618. View Biologics and JAK inhibitors for the treatment of monogenic systemic autoinflammatory diseases in children. Abstract

  36. Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. Front Immunol. 2022; 13:1068399. View Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. Abstract

  37. First-line options for systemic juvenile idiopathic arthritis treatment: an observational study of Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans. Pediatr Rheumatol Online J. 2022 Dec 08; 20(1):113. View First-line options for systemic juvenile idiopathic arthritis treatment: an observational study of Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans. Abstract

  38. mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. Nat Commun. 2022 11 28; 13(1):6915. View mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. Abstract

  39. Joint-Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis. Arthritis Rheumatol. 2022 11; 74(11):1851-1858. View Joint-Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis. Abstract

  40. VEXAS Syndrome and Disease Taxonomy in Rheumatology. Arthritis Rheumatol. 2022 11; 74(11):1733-1736. View VEXAS Syndrome and Disease Taxonomy in Rheumatology. Abstract

  41. TET2-mutant clonal hematopoiesis and risk of gout. Blood. 2022 09 08; 140(10):1094-1103. View TET2-mutant clonal hematopoiesis and risk of gout. Abstract

  42. Correction: Stoll et al. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children 2022, 9, 569. Children (Basel). 2022 Aug 02; 9(8). View Correction: Stoll et al. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children 2022, 9, 569. Abstract

  43. An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. J Rheumatol. 2022 Sep; 49(9):1042-1051. View An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. Abstract

  44. The Conundrum of Lung Disease and Drug Hypersensitivity-like Reactions in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2022 07; 74(7):1122-1131. View The Conundrum of Lung Disease and Drug Hypersensitivity-like Reactions in Systemic Juvenile Idiopathic Arthritis. Abstract

  45. Arthritis & Rheumatology: "Mid-Term" Report. Arthritis Rheumatol. 2022 07; 74(7):1099-1101. View Arthritis & Rheumatology: "Mid-Term" Report. Abstract

  46. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children (Basel). 2022 Apr 16; 9(4). View Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Abstract

  47. Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis. Blood Adv. 2022 04 12; 6(7):2081-2091. View Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis. Abstract

  48. Implications of Evolving Disease Classification for Drug Approval in Juvenile Idiopathic Arthritis. Paediatr Drugs. 2022 May; 24(3):185-191. View Implications of Evolving Disease Classification for Drug Approval in Juvenile Idiopathic Arthritis. Abstract

  49. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Arthritis Rheumatol. 2022 04; 74(4):570-585. View 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Abstract

  50. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2022 04; 74(4):521-537. View 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Abstract

  51. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Arthritis Care Res (Hoboken). 2022 04; 74(4):505-520. View 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Abstract

  52. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2022 04; 74(4):553-569. View 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Abstract

  53. Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint. Ann Rheum Dis. 2022 06; 81(6):805-814. View Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint. Abstract

  54. Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2022 Jan 15; 20(1):3. View Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis. Abstract

  55. Weekly Adalimumab, an Effective Alternative for Refractory Uveitis in Children. J Clin Rheumatol. 2022 Jan 01; 28(1):e301-e304. View Weekly Adalimumab, an Effective Alternative for Refractory Uveitis in Children. Abstract

  56. Arthritis flares mediated by tissue-resident memory T cells in the joint. Cell Rep. 2021 10 26; 37(4):109902. View Arthritis flares mediated by tissue-resident memory T cells in the joint. Abstract

  57. Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. JCI Insight. 2021 09 22; 6(18). View Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. Abstract

  58. IL-1ß-driven osteoclastogenic Tregs accelerate bone erosion in arthritis. J Clin Invest. 2021 09 15; 131(18). View IL-1ß-driven osteoclastogenic Tregs accelerate bone erosion in arthritis. Abstract

  59. Serologic Response to Borrelia Antigens Varies with Clinical Phenotype in Children and Young Adults with Lyme Disease. J Clin Microbiol. 2021 10 19; 59(11):e0134421. View Serologic Response to Borrelia Antigens Varies with Clinical Phenotype in Children and Young Adults with Lyme Disease. Abstract

  60. Genome editing to define the function of risk loci and variants in rheumatic disease. Nat Rev Rheumatol. 2021 08; 17(8):462-474. View Genome editing to define the function of risk loci and variants in rheumatic disease. Abstract

  61. A multidisciplinary assessment of pain in juvenile idiopathic arthritis. Semin Arthritis Rheum. 2021 08; 51(4):700-711. View A multidisciplinary assessment of pain in juvenile idiopathic arthritis. Abstract

  62. Effects of Estradiol on Immunoglobulin G Glycosylation: Mapping of the Downstream Signaling Mechanism. Front Immunol. 2021; 12:680227. View Effects of Estradiol on Immunoglobulin G Glycosylation: Mapping of the Downstream Signaling Mechanism. Abstract

  63. Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. Nat Immunol. 2021 06; 22(6):711-722. View Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. Abstract

  64. The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments. Nat Commun. 2021 05 17; 12(1):2856. View The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments. Abstract

  65. Comprehensive analysis of ADA2 genetic variants and estimation of carrier frequency driven by a function-based approach. J Allergy Clin Immunol. 2022 01; 149(1):379-387. View Comprehensive analysis of ADA2 genetic variants and estimation of carrier frequency driven by a function-based approach. Abstract

  66. Publisher Correction: Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nat Rev Rheumatol. 2021 May; 17(5):306. View Publisher Correction: Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Abstract

  67. A Picture Is Worth a Thousand Words, But Only If It Is a Good Picture. Arthritis Rheumatol. 2021 06; 73(6):912-913. View A Picture Is Worth a Thousand Words, But Only If It Is a Good Picture. Abstract

  68. Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nat Rev Rheumatol. 2021 05; 17(5):257-269. View Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Abstract

  69. Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity. PLoS One. 2021; 16(1):e0244187. View Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity. Abstract

  70. Estrogen-Driven Changes in Immunoglobulin G Fc Glycosylation. Exp Suppl. 2021; 112:341-361. View Estrogen-Driven Changes in Immunoglobulin G Fc Glycosylation. Abstract

  71. Intraperitoneal corticosteroids for recurrent ascites in patients with Fontan circulation: Initial clinical experience. J Card Surg. 2021 Feb; 36(2):735-738. View Intraperitoneal corticosteroids for recurrent ascites in patients with Fontan circulation: Initial clinical experience. Abstract

  72. COVID-19 cytokine storm: what is in a name? Ann Rheum Dis. 2021 01; 80(1):3-5. View COVID-19 cytokine storm: what is in a name? Abstract

  73. Reply. Arthritis Rheumatol. 2021 01; 73(1):176-178. View Reply. Abstract

  74. Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. J Clin Invest. 2020 11 02; 130(11):5942-5950. View Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. Abstract

  75. Monogenic autoinflammatory disorders: Conceptual overview, phenotype, and clinical approach. J Allergy Clin Immunol. 2020 11; 146(5):925-937. View Monogenic autoinflammatory disorders: Conceptual overview, phenotype, and clinical approach. Abstract

  76. Effects of estradiol on biological age measured using the glycan age index. Aging (Albany NY). 2020 Oct 13; 12(19):19756-19765. View Effects of estradiol on biological age measured using the glycan age index. Abstract

  77. The "Infodemic" of COVID-19. Arthritis Rheumatol. 2020 11; 72(11):1806-1808. View The "Infodemic" of COVID-19. Abstract

  78. NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus. Arthritis Rheumatol. 2020 10; 72(10):1707-1720. View NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus. Abstract

  79. Arthritis & Rheumatology: Evolving to Meet the Challenges of Rheumatology. Arthritis Rheumatol. 2020 08; 72(8):1254-1255. View Arthritis & Rheumatology: Evolving to Meet the Challenges of Rheumatology. Abstract

  80. The Fyn-Stat5 cascade is required for Fc? receptor-mediated mast cell function. Cell Immunol. 2020 10; 356:104134. View The Fyn-Stat5 cascade is required for Fc? receptor-mediated mast cell function. Abstract

  81. Identification of Prevotella Oralis as a possible target antigen in children with Enthesitis related arthritis. Clin Immunol. 2020 07; 216:108463. View Identification of Prevotella Oralis as a possible target antigen in children with Enthesitis related arthritis. Abstract

  82. On the Alert for Cytokine Storm: Immunopathology in COVID-19. Arthritis Rheumatol. 2020 07; 72(7):1059-1063. View On the Alert for Cytokine Storm: Immunopathology in COVID-19. Abstract

  83. Polyarteritis nodosa and deficiency of adenosine deaminase 2 - Shared genealogy, generations apart. Clin Immunol. 2020 06; 215:108411. View Polyarteritis nodosa and deficiency of adenosine deaminase 2 - Shared genealogy, generations apart. Abstract

  84. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. JCI Insight. 2020 03 26; 5(6). View Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. Abstract

  85. Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils. J Biol Chem. 2020 04 24; 295(17):5761-5770. View Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils. Abstract

  86. Response to: 'Total adenosine deaminase highly correlated with adenosine deaminase 2 activity in serum' by Gao et al. Ann Rheum Dis. 2022 02; 81(2):e31. View Response to: 'Total adenosine deaminase highly correlated with adenosine deaminase 2 activity in serum' by Gao et al. Abstract

  87. Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). J Allergy Clin Immunol. 2020 06; 145(6):1664-1672.e10. View Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). Abstract

  88. Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon. Arthritis Rheumatol. 2020 01; 72(1):100-113. View Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon. Abstract

  89. Megakaryocyte emperipolesis: a new frontier in cell-in-cell interaction. Platelets. 2020 Aug 17; 31(6):700-706. View Megakaryocyte emperipolesis: a new frontier in cell-in-cell interaction. Abstract

  90. Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Ann Rheum Dis. 2020 02; 79(2):225-231. View Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Abstract

  91. IgG Fc glycosylation as an axis of humoral immunity in childhood. J Allergy Clin Immunol. 2020 02; 145(2):710-713.e9. View IgG Fc glycosylation as an axis of humoral immunity in childhood. Abstract

  92. PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. JCI Insight. 2019 10 17; 4(20). View PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. Abstract

  93. SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20635-20643. View SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Abstract

  94. Storm Warning: Lung Disease in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2019 11; 71(11):1773-1775. View Storm Warning: Lung Disease in Systemic Juvenile Idiopathic Arthritis. Abstract

  95. Implications of juvenile idiopathic arthritis genetic risk variants for disease pathogenesis and classification. Curr Opin Rheumatol. 2019 09; 31(5):401-410. View Implications of juvenile idiopathic arthritis genetic risk variants for disease pathogenesis and classification. Abstract

  96. Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians. Nat Commun. 2019 08 21; 10(1):3765. View Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians. Abstract

  97. High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage. JCI Insight. 2019 08 08; 4(15). View High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage. Abstract

  98. Increased ILC3s associated with higher levels of IL-1ß aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase. Eur J Immunol. 2019 11; 49(11):2063-2073. View Increased ILC3s associated with higher levels of IL-1ß aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase. Abstract

  99. A role for G protein-coupled receptor 137b in bone remodeling in mouse and zebrafish. Bone. 2019 10; 127:104-113. View A role for G protein-coupled receptor 137b in bone remodeling in mouse and zebrafish. Abstract

  100. ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-?B via phosphoinosotide remodeling of endosomes. Nat Commun. 2019 05 21; 10(1):2247. View ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-?B via phosphoinosotide remodeling of endosomes. Abstract

  101. Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. Elife. 2019 05 01; 8. View Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. Abstract

  102. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Arthritis Rheumatol. 2019 06; 71(6):864-877. View 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Abstract

  103. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Arthritis Care Res (Hoboken). 2019 06; 71(6):717-734. View 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Abstract

  104. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Arthritis Rheumatol. 2019 06; 71(6):846-863. View 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Abstract

  105. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Arthritis Care Res (Hoboken). 2019 06; 71(6):703-716. View 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Abstract

  106. Antibody-dependent and -independent mechanisms of inflammatory arthritis. JCI Insight. 2019 03 07; 4(5). View Antibody-dependent and -independent mechanisms of inflammatory arthritis. Abstract

  107. Neutrophil Heterogeneity as Therapeutic Opportunity in Immune-Mediated Disease. Front Immunol. 2019; 10:346. View Neutrophil Heterogeneity as Therapeutic Opportunity in Immune-Mediated Disease. Abstract

  108. Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome. Pediatr Rheumatol Online J. 2019 Feb 14; 17(1):7. View Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome. Abstract

  109. Differential attenuation of ß2 integrin-dependent and -independent neutrophil migration by Ly6G ligation. Blood Adv. 2019 02 12; 3(3):256-267. View Differential attenuation of ß2 integrin-dependent and -independent neutrophil migration by Ly6G ligation. Abstract

  110. The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses. PLoS One. 2019; 14(2):e0211943. View The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses. Abstract

  111. Juvenile Idiopathic Arthritis: An Idea Whose Time Has Gone? J Rheumatol. 2019 02; 46(2):124-126. View Juvenile Idiopathic Arthritis: An Idea Whose Time Has Gone? Abstract

  112. Megakaryocytes as immune cells. J Leukoc Biol. 2019 06; 105(6):1111-1121. View Megakaryocytes as immune cells. Abstract

  113. Maestro endothelium conducts the neutrophils. Blood. 2018 10 25; 132(17):1734-1735. View Maestro endothelium conducts the neutrophils. Abstract

  114. Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Nat Genet. 2018 10; 50(10):1366-1374. View Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Abstract

  115. High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. Nat Genet. 2018 08; 50(8):1180-1188. View High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. Abstract

  116. Editorial: Toward Personalized Treatment for Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2018 08; 70(8):1172-1174. View Editorial: Toward Personalized Treatment for Systemic Juvenile Idiopathic Arthritis. Abstract

  117. Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2. J Allergy Clin Immunol. 2018 10; 142(4):1363-1365.e8. View Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2. Abstract

  118. Hip Synovial Fluid Cell Counts in Children From a Lyme Disease Endemic Area. Pediatrics. 2018 05; 141(5). View Hip Synovial Fluid Cell Counts in Children From a Lyme Disease Endemic Area. Abstract

  119. The Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans: Toward Comparative Effectiveness in the Pediatric Rheumatic Diseases. Arthritis Rheumatol. 2018 05; 70(5):669-678. View The Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans: Toward Comparative Effectiveness in the Pediatric Rheumatic Diseases. Abstract

  120. Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST). Clin Trials. 2018 06; 15(3):268-277. View Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST). Abstract

  121. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nat Commun. 2018 02 23; 9(1):789. View Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Abstract

  122. Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program. Arthritis Care Res (Hoboken). 2018 03; 70(3):445-453. View Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program. Abstract

  123. Age and fecal microbial strain-specific differences in patients with spondyloarthritis. Arthritis Res Ther. 2018 01 30; 20(1):14. View Age and fecal microbial strain-specific differences in patients with spondyloarthritis. Abstract

  124. Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2018 03; 70(3):409-419. View Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis. Abstract

  125. Mycobacterial infection induces higher interleukin-1ß and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase. PLoS One. 2017; 12(12):e0189453. View Mycobacterial infection induces higher interleukin-1ß and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase. Abstract

  126. High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis. Glycobiology. 2017 12 01; 27(12):1099-1108. View High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis. Abstract

  127. Review: Genetics and the Classification of Arthritis in Adults and Children. Arthritis Rheumatol. 2018 01; 70(1):7-17. View Review: Genetics and the Classification of Arthritis in Adults and Children. Abstract

  128. Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci. Arthritis Rheumatol. 2017 11; 69(11):2222-2232. View Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci. Abstract

  129. Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate. Rheumatology (Oxford). 2017 09 01; 56(9):1542-1551. View Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate. Abstract

  130. CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation. Blood. 2017 11 09; 130(19):2092-2100. View CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation. Abstract

  131. The metabolic regulator mTORC1 controls terminal myeloid differentiation. Sci Immunol. 2017 May 26; 2(11). View The metabolic regulator mTORC1 controls terminal myeloid differentiation. Abstract

  132. Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans. Pediatr Rheumatol Online J. 2017 Apr 11; 15(1):23. View Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans. Abstract

  133. Megakaryocytes compensate for Kit insufficiency in murine arthritis. J Clin Invest. 2017 May 01; 127(5):1714-1724. View Megakaryocytes compensate for Kit insufficiency in murine arthritis. Abstract

  134. Building an ARC to Grant Success: The Aims Review Committee. Arthritis Care Res (Hoboken). 2017 04; 69(4):459-461. View Building an ARC to Grant Success: The Aims Review Committee. Abstract

  135. Estrogens regulate glycosylation of IgG in women and men. JCI Insight. 2017 02 23; 2(4):e89703. View Estrogens regulate glycosylation of IgG in women and men. Abstract

  136. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017 02 01; 542(7639):110-114. View Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Abstract

  137. Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases. Ann Rheum Dis. 2017 04; 76(4):765-772. View Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases. Abstract

  138. Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis. Sci Transl Med. 2016 12 14; 8(369):369ra176. View Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis. Abstract

  139. Frequency and Morbidity of Temporomandibular Joint Involvement in Adult Patients With a History of Juvenile Idiopathic Arthritis. J Oral Maxillofac Surg. 2017 Jun; 75(6):1191-1200. View Frequency and Morbidity of Temporomandibular Joint Involvement in Adult Patients With a History of Juvenile Idiopathic Arthritis. Abstract

  140. Quantifying Temporomandibular Joint Synovitis in Children With Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2016 12; 68(12):1795-1802. View Quantifying Temporomandibular Joint Synovitis in Children With Juvenile Idiopathic Arthritis. Abstract

  141. Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses. Sci Rep. 2016 10 27; 6:35928. View Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses. Abstract

  142. The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1. PLoS Genet. 2016 09; 12(9):e1006292. View The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1. Abstract

  143. Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2016 07; 68(7):1758-68. View Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. Abstract

  144. Efficacy of an Interinstitutional Mentoring Program Within Pediatric Rheumatology. Arthritis Care Res (Hoboken). 2016 05; 68(5):645-51. View Efficacy of an Interinstitutional Mentoring Program Within Pediatric Rheumatology. Abstract

  145. Editorial: 21st Century Storm Chasers: Defining Macrophage Activation Syndrome. Arthritis Rheumatol. 2016 Mar; 68(3):557-60. View Editorial: 21st Century Storm Chasers: Defining Macrophage Activation Syndrome. Abstract

  146. Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis. Ann Rheum Dis. 2016 Nov; 75(11):2022-2028. View Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis. Abstract

  147. Autoinflammation and autoimmunity in systemic juvenile idiopathic arthritis. Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52):15785-6. View Autoinflammation and autoimmunity in systemic juvenile idiopathic arthritis. Abstract

  148. Increased pretreatment serum IFN-ß/a ratio predicts non-response to tumour necrosis factor a inhibition in rheumatoid arthritis. Ann Rheum Dis. 2016 10; 75(10):1757-62. View Increased pretreatment serum IFN-ß/a ratio predicts non-response to tumour necrosis factor a inhibition in rheumatoid arthritis. Abstract

  149. MICL controls inflammation in rheumatoid arthritis. Ann Rheum Dis. 2016 07; 75(7):1386-91. View MICL controls inflammation in rheumatoid arthritis. Abstract

  150. Redox Regulation of Pro-IL-1ß Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice. Antioxid Redox Signal. 2015 Oct 20; 23(12):973-84. View Redox Regulation of Pro-IL-1ß Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice. Abstract

  151. Inhibition of inflammatory arthritis using fullerene nanomaterials. PLoS One. 2015; 10(4):e0126290. View Inhibition of inflammatory arthritis using fullerene nanomaterials. Abstract

  152. Enthesitis as a component of dactylitis in psoriatic juvenile idiopathic arthritis: histology of an established clinical entity. Pediatr Rheumatol Online J. 2015; 13:7. View Enthesitis as a component of dactylitis in psoriatic juvenile idiopathic arthritis: histology of an established clinical entity. Abstract

  153. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment. PLoS One. 2015; 10(1):e0116812. View Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment. Abstract

  154. Evaluation of synovial mast cell functions in autoimmune arthritis. Methods Mol Biol. 2015; 1220:423-42. View Evaluation of synovial mast cell functions in autoimmune arthritis. Abstract

  155. Reply: To PMID 24623686. Arthritis Rheumatol. 2014 Sep; 66(9):2645-6. View Reply: To PMID 24623686. Abstract

  156. Adding canakinumab to the Childhood Arthritis and Rheumatology Research Alliance consensus treatment plans for systemic juvenile idiopathic arthritis: Comment on the article by DeWitt et al. Arthritis Care Res (Hoboken). 2014 Sep; 66(9):1430-1. View Adding canakinumab to the Childhood Arthritis and Rheumatology Research Alliance consensus treatment plans for systemic juvenile idiopathic arthritis: Comment on the article by DeWitt et al. Abstract

  157. Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Blood. 2014 Oct 02; 124(14):2173-83. View Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Abstract

  158. Highly parallel characterization of IgG Fc binding interactions. MAbs. 2014 Jul-Aug; 6(4):915-27. View Highly parallel characterization of IgG Fc binding interactions. Abstract

  159. IL-33/ST2 axis promotes mast cell survival via BCLXL. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10281-6. View IL-33/ST2 axis promotes mast cell survival via BCLXL. Abstract

  160. Review: is there a window of opportunity for treatment of systemic juvenile idiopathic arthritis? Arthritis Rheumatol. 2014 Jun; 66(6):1405-13. View Review: is there a window of opportunity for treatment of systemic juvenile idiopathic arthritis? Abstract

  161. Choosing Wisely: the American College of Rheumatology's Top 5 for pediatric rheumatology. Arthritis Care Res (Hoboken). 2014 May; 66(5):649-57. View Choosing Wisely: the American College of Rheumatology's Top 5 for pediatric rheumatology. Abstract

  162. A119: deep sequencing analysis of the T regulatory and T effector repertoire in juvenile idiopathic arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S156. View A119: deep sequencing analysis of the T regulatory and T effector repertoire in juvenile idiopathic arthritis. Abstract

  163. A161: Novel 3-Dimensional Explant Method Facilitates the Study of Lymphocyte Populations in the Synovium and Reveals a Large Population of Resident Memory T cells in Rheumatoid Arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S209. View A161: Novel 3-Dimensional Explant Method Facilitates the Study of Lymphocyte Populations in the Synovium and Reveals a Large Population of Resident Memory T cells in Rheumatoid Arthritis. Abstract

  164. A177: Program Evaluation of the ACR/CARRA Inter-Institutional Mentoring Program (AMIGO) in Pediatric Rheumatology. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S231. View A177: Program Evaluation of the ACR/CARRA Inter-Institutional Mentoring Program (AMIGO) in Pediatric Rheumatology. Abstract

  165. AMIGO: a novel approach to the mentorship gap in pediatric rheumatology. J Pediatr. 2014 Feb; 164(2):226-7.e1-3. View AMIGO: a novel approach to the mentorship gap in pediatric rheumatology. Abstract

  166. Congenital disorder of fucosylation type 2c (LADII) presenting with short stature and developmental delay with minimal adhesion defect. Hum Mol Genet. 2014 Jun 01; 23(11):2880-7. View Congenital disorder of fucosylation type 2c (LADII) presenting with short stature and developmental delay with minimal adhesion defect. Abstract

  167. Synovial fluid findings in children with knee monoarthritis in lyme disease endemic areas. Pediatr Emerg Care. 2014 Jan; 30(1):16-9. View Synovial fluid findings in children with knee monoarthritis in lyme disease endemic areas. Abstract

  168. Transition and transfer of adolescents and young adults with pediatric onset chronic disease: the patient and parent perspective. J Pediatr Rehabil Med. 2014; 7(1):43-51. View Transition and transfer of adolescents and young adults with pediatric onset chronic disease: the patient and parent perspective. Abstract

  169. Dr. Henderson, et al reply. J Rheumatol. 2013 Nov; 40(11):1926. View Dr. Henderson, et al reply. Abstract

  170. Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Sci Transl Med. 2013 Oct 30; 5(209):209ra150. View Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Abstract

  171. Sweets are good for you: fine tuning antibodies via glycosylation. Arthritis Rheum. 2013 Oct; 65(10):2541-4. View Sweets are good for you: fine tuning antibodies via glycosylation. Abstract

  172. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Arthritis Care Res (Hoboken). 2013 Oct; 65(10):1551-63. View 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Abstract

  173. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Arthritis Rheum. 2013 Oct; 65(10):2499-512. View 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Abstract

  174. Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet. 2013 Jun; 45(6):664-9. View Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Abstract

  175. Race, ethnicity, and disease outcomes in juvenile idiopathic arthritis: a cross-sectional analysis of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. J Rheumatol. 2013 Jun; 40(6):936-42. View Race, ethnicity, and disease outcomes in juvenile idiopathic arthritis: a cross-sectional analysis of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. Abstract

  176. Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. J Clin Invest. 2013 May; 123(5):2183-92. View Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. Abstract

  177. Ly6 family proteins in neutrophil biology. J Leukoc Biol. 2013 Oct; 94(4):585-94. View Ly6 family proteins in neutrophil biology. Abstract

  178. PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. J Autoimmun. 2013 Jun; 43:1-9. View PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. Abstract

  179. Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies. J Rheumatol. 2013 Mar; 40(3):273-81. View Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies. Abstract

  180. Ly6G: a work in progress--author's reply to Yipp. Blood. 2013 Jan 03; 121(1):242-3. View Ly6G: a work in progress--author's reply to Yipp. Abstract

  181. The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes. EMBO Mol Med. 2013 Feb; 5(2):235-49. View The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes. Abstract

  182. Characterization of fibrinogen glycosylation and its importance for serum/plasma N-glycome analysis. J Proteome Res. 2013 Jan 04; 12(1):444-54. View Characterization of fibrinogen glycosylation and its importance for serum/plasma N-glycome analysis. Abstract

  183. Interleukin-33 primes mast cells for activation by IgG immune complexes. PLoS One. 2012; 7(10):e47252. View Interleukin-33 primes mast cells for activation by IgG immune complexes. Abstract

  184. Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Arthritis Rheum. 2012 Sep; 64(9):3025-33. View Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Abstract

  185. Platelets: active players in the pathogenesis of arthritis and SLE. Nat Rev Rheumatol. 2012 Sep; 8(9):534-42. View Platelets: active players in the pathogenesis of arthritis and SLE. Abstract

  186. Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Arthritis Care Res (Hoboken). 2012 Jul; 64(7):1001-10. View Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Abstract

  187. Ly6G ligation blocks recruitment of neutrophils via a ß2-integrin-dependent mechanism. Blood. 2012 Aug 16; 120(7):1489-98. View Ly6G ligation blocks recruitment of neutrophils via a ß2-integrin-dependent mechanism. Abstract

  188. Platelets can enhance vascular permeability. Blood. 2012 Aug 09; 120(6):1334-43. View Platelets can enhance vascular permeability. Abstract

  189. Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis. J Biol Chem. 2012 Jun 08; 287(24):20047-55. View Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis. Abstract

  190. Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis. Arthritis Res Ther. 2012 Mar 05; 14(2):R43. View Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis. Abstract

  191. Clinical comparison of early-onset psoriatic and non-psoriatic oligoarticular juvenile idiopathic arthritis. Clin Exp Rheumatol. 2011 May-Jun; 29(3):582-8. View Clinical comparison of early-onset psoriatic and non-psoriatic oligoarticular juvenile idiopathic arthritis. Abstract

  192. Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Arthritis Rheum. 2011 Feb; 63(2):545-55. View Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Abstract

  193. C5a receptor enables participation of mast cells in immune complex arthritis independently of Fc? receptor modulation. Arthritis Rheum. 2010 Nov; 62(11):3322-33. View C5a receptor enables participation of mast cells in immune complex arthritis independently of Fc? receptor modulation. Abstract

  194. Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1). J Biol Chem. 2010 Jul 09; 285(28):21478-86. View Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1). Abstract

  195. Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1. Arthritis Rheum. 2010 Mar; 62(3):753-64. View Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1. Abstract

  196. Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science. 2010 Jan 29; 327(5965):580-3. View Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Abstract

  197. Juvenile psoriatic arthritis: bathwater or baby? J Rheumatol. 2009 Sep; 36(9):1861-3. View Juvenile psoriatic arthritis: bathwater or baby? Abstract

  198. Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes. J Immunol. 2009 Jan 01; 182(1):647-56. View Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes. Abstract

  199. Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy. Am J Pathol. 2008 Dec; 173(6):1693-701. View Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy. Abstract

  200. Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Arthritis Rheum. 2008 May; 58(5):1354-65. View Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Abstract

  201. Comparison of Vancouver and International League of Associations for rheumatology classification criteria for juvenile psoriatic arthritis. Arthritis Rheum. 2008 Jan 15; 59(1):51-8. View Comparison of Vancouver and International League of Associations for rheumatology classification criteria for juvenile psoriatic arthritis. Abstract

  202. Overview of hip pain in childhood. 2008.

  203. Tumor necrosis factor receptor-1 associated periodic syndrome (TRAPS). 2008.

  204. Evaluation of the child with back pain. 2008.

  205. Overview of the causes of back pain in children and adolescents. 2008.

  206. Mast cells. Rheumatoid Arthritis. Hochberg MC, Silman AJ, Smolen JS, Weisman MH, Weinblatt ME (in press). 2008.

  207. Periodic fever syndromes and other autoinflammatory diseases: An overview. 2008.

  208. Hemarthrosis. 2008.

  209. Mast cells. Kelley's Textbook of Rheumatology. Firestein GS, Budd RC, Harris ED, McInnes IB, Ruddy S, Sergent JS (in press). 2008; in press.

  210. Mast cells contribute to autoimmune inflammatory arthritis via tryptase•heparin complexes . (submitted). 2008.

  211. Laboratory and imaging studies in rheumatology. Rudolph's Pediatrics. (in press). 2008.

  212. Synovial mast cells: role in acute and chronic arthritis. Immunol Rev. 2007 Jun; 217:19-37. View Synovial mast cells: role in acute and chronic arthritis. Abstract

  213. Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2325-30. View Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1. Abstract

  214. Mast cells in acute and chronic inflammatory arthritis. Immunol Rev. 2007; 217:19-37.

  215. Patients with juvenile psoriatic arthritis comprise two distinct populations. Arthritis Rheum. 2006 Nov; 54(11):3564-72. View Patients with juvenile psoriatic arthritis comprise two distinct populations. Abstract

  216. Subpopulations within juvenile psoriatic arthritis: a review of the literature. Clin Dev Immunol. 2006 Jun-Dec; 13(2-4):377-80. View Subpopulations within juvenile psoriatic arthritis: a review of the literature. Abstract

  217. Extreme thrombocytosis predicts Kawasaki disease in infants. Clin Pediatr (Phila). 2006 Jun; 45(5):446-52. View Extreme thrombocytosis predicts Kawasaki disease in infants. Abstract

  218. Care of the adult with juvenile rheumatoid arthritis. Arthritis Rheum. 2006 Apr 15; 55(2):208-16. View Care of the adult with juvenile rheumatoid arthritis. Abstract

  219. Neutrophil-derived leukotriene B4 is required for inflammatory arthritis. J Exp Med. 2006 Apr 17; 203(4):837-42. View Neutrophil-derived leukotriene B4 is required for inflammatory arthritis. Abstract

  220. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006 Mar; 7(3):284-92. View Particularities of the vasculature can promote the organ specificity of autoimmune attack. Abstract

  221. Innate immunity and immune complexes in rheumatoid arthritis. Rheumatoid Arthritis: New Frontiers in Pathogenesis and Treatment, G.S. Firestein, G.S. Panayi, F.A. Wollheim (eds.). 2006.

  222. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Pediatrics. 2005 Jul; 116(1):e89-93. View Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Abstract

  223. Mast cells in autoantibody responses and arthritis. Novartis Found Symp. 2005; 271:200-9; discussion 210-4. View Mast cells in autoantibody responses and arthritis. Abstract

  224. Anti-inflammatory and immunomodulatory therapy. Comprehensive Pediatrics, Osborn LM, DeWitt TG, First LR, Zenel JA (eds). 2005.

  225. Mast cells in inflammatory arthritis. Arthritis Res Ther. 2005; 7(1):1-11. View Mast cells in inflammatory arthritis. Abstract

  226. Raynaud's phenomenon in children: a retrospective review of 123 patients. Pediatrics. 2003 Apr; 111(4 Pt 1):715-21. View Raynaud's phenomenon in children: a retrospective review of 123 patients. Abstract

  227. Spanish for Pediatric Medicine. 2003.

  228. Kawasaki syndrome and acquired heart disease. J Musculoskel Med. 2002; 19:65-75.

  229. Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency. Mayo Clin Proc. 2002 Jan; 77(1):92-6. View Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency. Abstract

  230. Treatment of TRAPS with etanercept: use in pediatrics. Clin Exp Rheumatol. 2001 Jul-Aug; 19(4):484-5. View Treatment of TRAPS with etanercept: use in pediatrics. Abstract

  231. Treatment of allergic asthma with monoclonal anti-IgE antibody. Pediatrics. 2001; 108:S566-567.

  232. Tuberculosis in Los Lomas Zaragoza, Chimaltenango. 1994.

American Board of Pediatrics (Rheumatology) | Education

Medical School

Harvard Medical School

2011, Boston, MA

Residency

Massachusetts General Hospital

2014, Boston, MA

Fellowship

Boston Children's Hospital

2017, Boston, MA

American Board of Pediatrics (Rheumatology) | Publications

American Board of Pediatrics (Rheumatology) | Education

Medical School

Istanbul School of Medicine

1986, Istanbul, Turkey

Residency

Monmouth Medical Center

1999, Long Branch, NJ

Fellowship

Boston Children's Hospital

2003, Boston, MA

American Board of Pediatrics (Rheumatology) | Publications

American Board of Pediatrics (Rheumatology) | Education

Undergraduate School

Harvard University

2008, Cambridge, MA

Medical School

University of Pennsylvania

2012, Philadelphia, PA

Internship

Children's Hospital of Philadelphia

2013, Philadelphia, PA

Residency

Children's Hospital of Philadelphia

2015, Philadelphia, PA

Fellowship

Children's Hospital of Philadelphia

2018, Philadelphia, PA

American Board of Pediatrics (Rheumatology) | Publications

Talk to Lesley

If this is a medical emergency, please dial 9-1-1. This application should not be used in an emergency. This chat is being transmitted via a secure connection.

Hi! My name is Lesley. I am a virtual agent programmed to help you. If you would like to speak to a live agent, please call 617-355-6000.

I am unable to answer specific questions regarding your child's case, including appointments and conditions/diagnosis. Please contact your physician's office.

Quick links:

- MyChildrens Portal
- Global Services
- Find a Doctor
- Find a Location
- Programs and Services