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Research & Innovation | Overview

Research in anesthesiology includes more than developing and improving the drugs and equipment that provide sedation, anesthesia, or pain control. Our research encompasses the entire range of basic, translational, and clinical biological and bioengineering sciences, including:

  • developmental biology
  • organ pathophysiology
  • design of life function monitoring equipment
  • outcomes research
  • quality and safety improvement

Our team is involved in many efforts to improve the outcome and long-term well-being of children and adults with congenital heart disease.

Recent research areas include:

  • understanding changes in the function of blood clotting systems in patients with congenital heart disease and during cardiac surgery, and improving therapies to reduce blood loss and the need for blood transfusion
  • clarifying the role of the body’s inflammatory mechanisms on the effects of the heart-lung machine and heart surgery in infants and older patients
  • exploring ways to preserve heart function in patients with congenital heart disease, both after cardiac surgery and long-term, to improve their outcomes
  • developing advanced monitoring techniques, such as near-infrared spectroscopy, to improve brain and other organ functions after cardiac surgery
  • understanding the effects of surgery and anesthetic agents on the body’s defense and repair mechanisms
  • defining risk factors in patients with congenital heart disease who require cardiac or non-cardiac surgery interventions to reduce adverse events
  • using tissue engineering approaches to repair defective cardiac conduction systems and heart function in patients with congenital heart disease
  • designing methods for administering oxygen and other gases intravenously as an adjunct to life support and organ preservation
  • understanding the pharmacokinetics of sedatives and analgesics on extracorporeal support including cardiopulmonary bypass

A list of recent publications by the cardiac anesthesia division is available at this link.