Current Environment: Production

Medical Services

Specialties

Programs & Services

Languages

  • English

Education

Undergraduate School

Ithaca College

2005, Ithaca, NY

Graduate School

University of Connecticut

2013, Farmington, CT

Medical School

University of Connecticut

2013, Farmington, CT

Internship

Mt. Auburn Hospital

2014, Cambridge, MA

Residency

Massachusetts Eye and Ear Infirmary

2017, Boston, MA

Fellowship

Massachusetts Eye and Ear Infirmary

2018, Boston, MA

Fellowship

Boston Children's Hospital

2019, Boston, MA

Certifications

  • American Board of Ophthalmology (General)

Media

Caregiver Profile

Meet Dr. Eric Gaier

Publications

  1. Retinal findings in pediatric idiopathic intracranial hypertension. J AAPOS. 2025 Apr; 29(2):104179. View Abstract

  2. More than double. J AAPOS. 2025 Apr; 29(2):104161. View Abstract

  3. Decreased scene-selective activity within the posterior intraparietal cortex in amblyopic adults. Front Neurosci. 2025; 19:1527148. View Abstract

  4. Sociodemographic Disparities in Uncorrectable Visual Impairment Among US Adolescents. Am J Ophthalmol. 2025 May; 273:248-254. View Abstract

  5. Differential Impacts of Strabismic and Anisometropic Amblyopia on the Mesoscale Functional Organization of the Human Visual Cortex. J Neurosci. 2025 Feb 05; 45(6). View Abstract

  6. Cortical responses to conflicting binocular stimuli in mouse primary visual cortex. bioRxiv. 2025 Jan 01. View Abstract

  7. Ocular neuromyotonia after peribulbar block. J AAPOS. 2025 Feb; 29(1):104096. View Abstract

  8. Acquired torticollis due to an ocular surface foreign body. J AAPOS. 2025 Apr; 29(2):104097. View Abstract

  9. Using the visual cliff and pole descent assays to detect binocular disruption in mice. bioRxiv. 2024 Sep 25. View Abstract

  10. Case 25-2024: A 12-Year-Old Boy with Autism and Decreased Vision. N Engl J Med. 2024 Aug 15; 391(7):641-650. View Abstract

  11. Spontaneous recovery from amblyopia following fellow eye vision loss: a systematic review and narrative synthesis. J AAPOS. 2024 08; 28(4):103971. View Abstract

  12. Optic Nerve T2 Signal Intensity and Caliber Reflect Clinical Severity in Genetic Optic Atrophy. J Neuroophthalmol. 2025 Jun 01; 45(2):145-152. View Abstract

  13. Long-term visual outcomes in spasmus nutans. BMC Ophthalmol. 2024 Jun 12; 24(1):253. View Abstract

  14. Decreased scene-selective activity within the posterior intraparietal cortex in amblyopic adults. bioRxiv. 2024 Jun 08. View Abstract

  15. Vision Loss and Difficulty Walking in a Pediatric Sexual Assault Victim. J Neuroophthalmol. 2024 Sep 01; 44(3):e498-e499. View Abstract

  16. Ocular lichen planus as a cause of recurrent restrictive strabismus. J AAPOS. 2024 06; 28(3):103920. View Abstract

  17. Aberrant regeneration of accommodation in pediatric inferior division oculomotor palsy. J AAPOS. 2024 06; 28(3):103917. View Abstract

  18. Reply: Isolated Sixth Nerve Palsy and COVID-19. J Neuroophthalmol. 2024 Dec 01; 44(4):e536. View Abstract

  19. Reply: SARS-CoV-2-Related Cranial Nerve-6 Palsy Should Not Be Confused With Orbital Myositis Affecting the Lateral Rectus Muscle. J Neuroophthalmol. 2024 Dec 01; 44(4):e534-e535. View Abstract

  20. Artificial Intelligence to Differentiate Pediatric Pseudopapilledema and True Papilledema on Fundus Photographs. Ophthalmol Sci. 2024 Jul-Aug; 4(4):100496. View Abstract

  21. Using high-resolution functional MRI to differentiate impacts of strabismic and anisometropic amblyopia on evoked ocular dominance activity in humans. bioRxiv. 2024 Feb 13. View Abstract

  22. Reply. J AAPOS. 2024 02; 28(1):103825. View Abstract

  23. Cauterization-mediated restriction from penetrating orbital trauma. J AAPOS. 2024 02; 28(1):103805. View Abstract

  24. Comments on: Partial Recovery of Amblyopia After Fellow Eye Ischemic Optic Neuropathy: Response. J Neuroophthalmol. 2024 Mar 01; 44(1):e210-e211. View Abstract

  25. Reply. Ophthalmology. 2024 Jan; 131(1):e5. View Abstract

  26. Amblyopia treatment outcomes in patients with neurodevelopmental disorders. J AAPOS. 2023 10; 27(5):276.e1-276.e8. View Abstract

  27. Isolated Sixth Nerve Palsy and COVID-19: A Recurrent Case in a 7-Month-Old Child and Analysis of Reported Cases. J Neuroophthalmol. 2023 Aug 30. View Abstract

  28. Isolated Sixth Nerve Palsy and COVID-19: A Recurrent Case in a 7-Month-Old Child and Analysis of Reported Cases. J Neuroophthalmol. 2024 09 01; 44(3):301-307. View Abstract

  29. Factors associated with visual acuity improvement with a binocular digital therapeutic for amblyopia. J AAPOS. 2023 10; 27(5):300-303. View Abstract

  30. Durable recovery from amblyopia with donepezil. Sci Rep. 2023 06 22; 13(1):10161. View Abstract

  31. Neuro-ophthalmic Complications in Pediatric Leukemia. J Neuroophthalmol. 2023 12 01; 43(4):520-524. View Abstract

  32. Recovery from Amblyopia in Adulthood: A Meta-Analysis. medRxiv. 2023 May 28. View Abstract

  33. Eye Swelling and Decreased Vision in a Patient With Autism. J Neuroophthalmol. 2023 06 01; 43(2):e63. View Abstract

  34. Outcomes of Zone 3 Open Globe Injuries by Wound Extent: Subcategorization of Zone 3 Injuries Segregates Visual and Anatomic Outcomes. Ophthalmology. 2023 04; 130(4):379-386. View Abstract

  35. Membrane Frizzled-Related Protein-Related Disease Mimicking Idiopathic Intracranial Hypertension. J Neuroophthalmol. 2024 Mar 01; 44(1):e26-e28. View Abstract

  36. Periodic Trends in Internet Searches for Ocular Symptoms in the US. Ophthalmic Epidemiol. 2023 08; 30(4):352-357. View Abstract

  37. Metaplasticity: a key to visual recovery from amblyopia in adulthood? Curr Opin Ophthalmol. 2022 Nov 01; 33(6):512-518. View Abstract

  38. Reply. Ophthalmology. 2022 Oct; 129(10):e152-e153. View Abstract

  39. Prevalence and Characteristics of Cytomegalovirus Ocular Disease in Children: A Multi-Center Study. Clin Ophthalmol. 2022; 16:2209-2217. View Abstract

  40. Partial Recovery of Amblyopia After Fellow Eye Ischemic Optic Neuropathy. J Neuroophthalmol. 2023 03 01; 43(1):76-81. View Abstract

  41. Optic Perineuritis Associated With Cryptococcal Meningitis Presenting With a "Hot Orbit" in a Patient With Chronic Lymphocytic Leukemia. J Neuroophthalmol. 2022 06 01; 42(2):272-277. View Abstract

  42. Peripapillary Choroidal Vascularity and Visual Correlates in Non-Arteritic Anterior Ischemic Optic Neuropathy Using Swept-Source Optical Coherence Tomography. Front Ophthalmol (Lausanne). 2022; 2. View Abstract

  43. Detection of Choroidal Hypoperfusion in Giant Cell Arteritis Using Swept-Source Optical Coherence Tomographic Angiography. J Neuroophthalmol. 2023 12 01; 43(4):e117-e119. View Abstract

  44. Reversal of Visual Loss From Skull Base Osteomyelitis in a Pediatric Patient. J Neuroophthalmol. 2021 Dec 01; 41(4):e728-e730. View Abstract

  45. Anterior Ischemic Optic Neuropathy Secondary to Carotid Artery Dissection. J Neuroophthalmol. 2021 Dec 01; 41(4):e731-e733. View Abstract

  46. Comment on "Fatal GNAQ-mutated CNS melanoma in an adolescent with nevus of Ota". Pediatr Dermatol. 2021 11; 38(6):1608-1609. View Abstract

  47. Evaluation of the Relationship Between Preferential Looking Testing and Visual Evoked Potentials as a Biomarker of Cerebral Visual Impairment. Front Hum Neurosci. 2021; 15:769259. View Abstract

  48. Sectoral Sparing Associated With a Cilioretinal Artery in Arteritic Anterior Ischemic Optic Neuropathy. J Neuroophthalmol. 2022 06 01; 42(2):e514-e516. View Abstract

  49. Adverse Ocular Events following COVID-19 Vaccination. Inflamm Res. 2021 Dec; 70(10-12):1005-1009. View Abstract

  50. Randomized Controlled Trial of a Dichoptic Digital Therapeutic for Amblyopia. Ophthalmology. 2022 01; 129(1):77-85. View Abstract

  51. Ptosis as Clinical Presentation in a Patient With Emery-Dreifuss Muscular Dystrophy Type 5. J Neuroophthalmol. 2021 09 01; 41(3):e333-e334. View Abstract

  52. Absent Foveal Avascular Zone in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. J Neuroophthalmol. 2021 06 01; 41(2):e166-e168. View Abstract

  53. Digital therapeutic improves visual acuity and encourages high adherence in amblyopic children in open-label pilot study. J AAPOS. 2021 04; 25(2):87.e1-87.e6. View Abstract

  54. Microvasculopathy in Lyme-Associated Papillitis Revealed by Optical Coherence Tomographic Angiography. J Neuroophthalmol. 2022 03 01; 42(1):e338-e340. View Abstract

  55. Serum Biomarkers in Neuro-Ophthalmology: When to Test. Semin Ophthalmol. 2021 May 19; 36(4):322-328. View Abstract

  56. Emerging therapies for amblyopia. Semin Ophthalmol. 2021 May 19; 36(4):282-288. View Abstract

  57. Pseudo-Duane retraction syndrome after orbital myositis. J AAPOS. 2021 04; 25(2):121-123. View Abstract

  58. Persistent vasa hyaloidea propria/retinae in familial exudative vitreoretinopathy. J AAPOS. 2021 04; 25(2):114-116. View Abstract

  59. Improved adherence and treatment outcomes with an engaging, personalized digital therapeutic in amblyopia. Sci Rep. 2020 05 20; 10(1):8328. View Abstract

  60. Virtual Visits in Ophthalmology: Timely Advice for Implementation During the COVID-19 Public Health Crisis. Telemed J E Health. 2020 09; 26(9):1113-1117. View Abstract

  61. Novel homozygous OPA3 mutation in an Afghani family with 3-methylglutaconic aciduria type III and optic atrophy. Ophthalmic Genet. 2019 12; 40(6):570-573. View Abstract

  62. Pediatric Idiopathic Intracranial Hypertension. Semin Neurol. 2019 12; 39(6):704-710. View Abstract

  63. Poor prognoses of open globe injuries with concomitant orbital fractures. Orbit. 2020 Aug; 39(4):241-250. View Abstract

  64. Diagnosis and Imaging of Optic Nerve Head Drusen. Semin Ophthalmol. 2019; 34(4):256-263. View Abstract

  65. Imaging Amblyopia: Insights from Optical Coherence Tomography (OCT). Semin Ophthalmol. 2019; 34(4):303-311. View Abstract

  66. Quantitative analysis of optical coherence tomographic angiography (OCT-A) in patients with non-arteritic anterior ischemic optic neuropathy (NAION) corresponds to visual function. PLoS One. 2018; 13(6):e0199793. View Abstract

  67. Pseudohemangioma in Nonarteritic Anterior Ischemic Optic Neuropathy. Ophthalmology. 2018 06; 125(6):903. View Abstract

  68. Bilateral uveal effusions in a 23-year-old man. Digit J Ophthalmol. 2018; 24(3):13-15. View Abstract

  69. Double Optic Disc Pit With Glial Plugs Imaged by Wide-Field Optical Coherence Tomography. Ophthalmic Surg Lasers Imaging Retina. 2018 01 01; 49(1):52-54. View Abstract

  70. Focal Capillary Dropout Associated With Optic Disc Drusen Using Optical Coherence Tomographic Angiography. J Neuroophthalmol. 2017 12; 37(4):405-410. View Abstract

  71. Optical coherence tomographic angiography identifies peripapillary microvascular dilation and focal non-perfusion in giant cell arteritis. Br J Ophthalmol. 2018 08; 102(8):1141-1146. View Abstract

  72. Congenital anomalies of the optic disc: insights from optical coherence tomography imaging. Curr Opin Ophthalmol. 2017 Nov; 28(6):579-586. View Abstract

  73. Diagnostic genetic testing for patients with bilateral optic neuropathy and comparison of clinical features according to OPA1 mutation status. Mol Vis. 2017; 23:548-560. View Abstract

  74. Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography. Ophthalmology. 2017 08; 124(8):1174. View Abstract

  75. PV16-Positive Invasive Conjunctival Squamous Cell Carcinoma in an Anophthalmic Socket. Ophthalmic Plast Reconstr Surg. 2017 May/Jun; 33(3S Suppl 1):S2-S4. View Abstract

  76. Combined Central Retinal Vein Occlusion and Central Retinal Arterial Obstruction with Cilioretinal Artery Sparing. Ophthalmology. 2017 04; 124(4):576. View Abstract

  77. Advances in Amblyopia Treatment: Paradigm Shifts and Future Directions. Int Ophthalmol Clin. 2017; 57(4):117-128. View Abstract

  78. The enigma of nonarteritic anterior ischemic optic neuropathy: an update for the comprehensive ophthalmologist. Curr Opin Ophthalmol. 2016 Nov; 27(6):498-504. View Abstract

  79. Peripapillary Capillary Dilation in Leber Hereditary Optic Neuropathy Revealed by Optical Coherence Tomographic Angiography. JAMA Ophthalmol. 2016 11 01; 134(11):1332-1334. View Abstract

  80. Demographic, Systemic, and Ocular Factors Associated with Nonarteritic Anterior Ischemic Optic Neuropathy. Ophthalmology. 2016 12; 123(12):2446-2455. View Abstract

  81. Atypical Optic Neuritis. Curr Neurol Neurosci Rep. 2015 Dec; 15(12):76. View Abstract

  82. Genetics of Primary Inherited Disorders of the Optic Nerve: Clinical Applications. Cold Spring Harb Perspect Med. 2015 Jul 01; 5(7):a017277. View Abstract

  83. Genetic determinants of amidating enzyme activity and its relationship with metal cofactors in human serum. BMC Endocr Disord. 2014 Jul 15; 14:58. View Abstract

  84. Pam heterozygous mice reveal essential role for Cu in amygdalar behavioral and synaptic function. Ann N Y Acad Sci. 2014 May; 1314:15-23. View Abstract

  85. In vivo and in vitro analyses of amygdalar function reveal a role for copper. J Neurophysiol. 2014 May; 111(10):1927-39. View Abstract

  86. Peptidylglycine a-amidating monooxygenase heterozygosity alters brain copper handling with region specificity. J Neurochem. 2013 Dec; 127(5):605-19. View Abstract

  87. Copper signaling in the mammalian nervous system: synaptic effects. J Neurosci Res. 2013 Jan; 91(1):2-19. View Abstract

  88. High serum Cu and Cu/Zn ratios correlate with impairments in bone density, physical performance and overall health in a population of elderly men with frailty characteristics. Exp Gerontol. 2012 Jul; 47(7):491-6. View Abstract

  89. Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses. J Neurosci. 2010 Oct 13; 30(41):13656-69. View Abstract

  90. Kalirin-7 is required for synaptic structure and function. J Neurosci. 2008 Nov 19; 28(47):12368-82. View Abstract

  91. Amine modulation of Ih in a small neural network. J Neurophysiol. 2006 Dec; 96(6):2931-40. View Abstract

  92. Low conductance gap junctions mediate specific electrical coupling in body-wall muscle cells of Caenorhabditis elegans. J Biol Chem. 2006 Mar 24; 281(12):7881-9. View Abstract

As a physician-scientist and pediatric neuro-ophthalmologist, I focus on treating children with vision and/or eye movement disorders rooted in the nervous system, with the goal of optimizing their visual function and experience over their lifetimes.