Elena Crestani

RELMß sets the threshold for microbiome-dependent oral tolerance. Nature. 2025 Feb; 638(8051):760-768. View RELMß sets the threshold for microbiome-dependent oral tolerance. Abstract

Notch4 regulatory T cells and SARS-CoV-2 viremia shape COVID19 survival outcome. Allergy. 2025 Feb; 80(2):557-569. View Notch4 regulatory T cells and SARS-CoV-2 viremia shape COVID19 survival outcome. Abstract

An Atypical Case of Parotid Swelling. Pediatr Rev. 2024 Sep 01; 45(9):535-539. View An Atypical Case of Parotid Swelling. Abstract

Age-specific Metabolomic profiles in children with food allergy. Clin Immunol. 2024 04; 261:109928. View Age-specific Metabolomic profiles in children with food allergy. Abstract

Piloting a multidisciplinary group education session to support caregivers of children with food protein-induced enterocolitis syndrome (FPIES). J Allergy Clin Immunol Pract. 2023 Oct; 11(10):3260-3262.e1. View Piloting a multidisciplinary group education session to support caregivers of children with food protein-induced enterocolitis syndrome (FPIES). Abstract

The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. J Clin Invest. 2023 01 03; 133(1). View The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. Abstract

SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children. Clin Immunol. 2022 Oct; 243:109106. View SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children. Abstract

A common IL-4 receptor variant promotes asthma severity via a Treg cell GRB2-IL-6-Notch4 circuit. Allergy. 2022 11; 77(11):3377-3387. View A common IL-4 receptor variant promotes asthma severity via a Treg cell GRB2-IL-6-Notch4 circuit. Abstract

Atopic Dermatitis Mediates the Association Between an IL4RA Variant and Food Allergy in School-Aged Children. J Allergy Clin Immunol Pract. 2022 08; 10(8):2117-2124.e4. View Atopic Dermatitis Mediates the Association Between an IL4RA Variant and Food Allergy in School-Aged Children. Abstract

Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. Res Sq. 2022 Apr 11. View Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. Abstract

A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune-epithelial interface. Proc Natl Acad Sci U S A. 2022 01 04; 119(1). View A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune-epithelial interface. Abstract

Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nat Immunol. 2021 Jun; 22(6):794-795. View Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Abstract

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021 06 08; 54(6):1186-1199.e7. View Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Abstract

Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nat Immunol. 2021 Jan; 22(1):100. View Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Abstract

Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Immunity. 2020 Dec 15; 53(6):1331-1332. View Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Abstract

Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Immunity. 2020 12 15; 53(6):1202-1214.e6. View Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Abstract

Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. J Allergy Clin Immunol Pract. 2020 10; 8(9S):S16-S116. View Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. Abstract

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nat Immunol. 2020 11; 21(11):1359-1370. View A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Abstract

Dietary and Microbial Determinants in Food Allergy. Immunity. 2020 08 18; 53(2):277-289. View Dietary and Microbial Determinants in Food Allergy. Abstract

Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma. J Allergy Clin Immunol. 2020 03; 145(3):897-906. View Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma. Abstract

Author Correction: Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. Nat Med. 2019 Sep; 25(9):1458. View Author Correction: Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. Abstract

Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. Am J Hum Genet. 2019 09 05; 105(3):549-561. View Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. Abstract

Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. Nat Med. 2019 07; 25(7):1164-1174. View Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. Abstract

Systemic Reactions in Pediatric Patients Receiving Standardized Allergen Subcutaneous Immunotherapy with and without Seasonal Dose Adjustment. J Allergy Clin Immunol Pract. 2018 Sep - Oct; 6(5):1711-1716.e4. View Systemic Reactions in Pediatric Patients Receiving Standardized Allergen Subcutaneous Immunotherapy with and without Seasonal Dose Adjustment. Abstract

Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):476-485.e3. View Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial. Abstract

Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016 10 17; 213(11):2413-2435. View Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. Abstract

Autoimmune lymphoproliferative syndrome caused by a homozygous FasL mutation that disrupts FasL assembly. J Allergy Clin Immunol. 2016 Jan; 137(1):324-327.e2. View Autoimmune lymphoproliferative syndrome caused by a homozygous FasL mutation that disrupts FasL assembly. Abstract

Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia. J Allergy Clin Immunol. 2015 Nov; 136(5):1401-4.e1-3. View Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia. Abstract

RAG1 deficiency may present clinically as selective IgA deficiency. J Clin Immunol. 2015 Apr; 35(3):280-8. View RAG1 deficiency may present clinically as selective IgA deficiency. Abstract

IgE-mediated hypersensitivity reaction and desensitization to glatiramer acetate in a pediatric patient. Pediatr Allergy Immunol. 2014 Dec; 25(8):821-3. View IgE-mediated hypersensitivity reaction and desensitization to glatiramer acetate in a pediatric patient. Abstract

RAG1 reversion mosaicism in a patient with Omenn syndrome. J Clin Immunol. 2014 Jul; 34(5):551-4. View RAG1 reversion mosaicism in a patient with Omenn syndrome. Abstract

Association of IL-5 cytokine production and in vivo IgE levels in infants and parents. J Allergy Clin Immunol. 2007 Oct; 120(4):820-6. View Association of IL-5 cytokine production and in vivo IgE levels in infants and parents. Abstract

Exhaled air temperature in asthma: methods and relationship with markers of disease. Clin Exp Allergy. 2007 Mar; 37(3):415-9. View Exhaled air temperature in asthma: methods and relationship with markers of disease. Abstract

Parental asthma as a risk factor for the development of early skin test sensitization in children. J Allergy Clin Immunol. 2004 Feb; 113(2):284-90. View Parental asthma as a risk factor for the development of early skin test sensitization in children. Abstract

Fractionated total body irradiation in bone marrow transplantation--an emphasis on lung dosimetry. Australas Radiol. 1983 Jul; 27(2):186-94. View Fractionated total body irradiation in bone marrow transplantation--an emphasis on lung dosimetry. Abstract