Seth Rakoff-Nahoum

Enteric glia regulate Paneth cell secretion and intestinal microbial ecology. Elife. 2025 Apr 14; 13. View Enteric glia regulate Paneth cell secretion and intestinal microbial ecology. Abstract

Functional diversification of dietary plant small molecules by the gut microbiome. Cell. 2025 Apr 03; 188(7):1967-1983.e22. View Functional diversification of dietary plant small molecules by the gut microbiome. Abstract

RELMß sets the threshold for microbiome-dependent oral tolerance. Nature. 2025 Feb; 638(8051):760-768. View RELMß sets the threshold for microbiome-dependent oral tolerance. Abstract

Enteric glia regulate Paneth cell secretion and intestinal microbial ecology. bioRxiv. 2024 Dec 23. View Enteric glia regulate Paneth cell secretion and intestinal microbial ecology. Abstract

ABO blood groups and galectins: Implications in transfusion medicine and innate immunity. Semin Immunol. 2024 Jul-Sep; 74-75:101892. View ABO blood groups and galectins: Implications in transfusion medicine and innate immunity. Abstract

Galectin-4 Antimicrobial Activity Primarily Occurs Through its C-Terminal Domain. Mol Cell Proteomics. 2024 May; 23(5):100747. View Galectin-4 Antimicrobial Activity Primarily Occurs Through its C-Terminal Domain. Abstract

Stress Ulcer Prophylaxis Versus Placebo-A Blinded Pilot Randomized Controlled Trial to Evaluate the Safety of Two Strategies in Critically Ill Infants With Congenital Heart Disease. Pediatr Crit Care Med. 2024 Feb 01; 25(2):118-127. View Stress Ulcer Prophylaxis Versus Placebo-A Blinded Pilot Randomized Controlled Trial to Evaluate the Safety of Two Strategies in Critically Ill Infants With Congenital Heart Disease. Abstract

C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation. Nature. 2023 Oct; 622(7983):611-618. View C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation. Abstract

Blood group A enhances SARS-CoV-2 infection. Blood. 2023 08 24; 142(8):742-747. View Blood group A enhances SARS-CoV-2 infection. Abstract

Bacterial amylases enable glycogen degradation by the vaginal microbiome. Nat Microbiol. 2023 09; 8(9):1641-1652. View Bacterial amylases enable glycogen degradation by the vaginal microbiome. Abstract

Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip. Microbiome. 2022 11 26; 10(1):201. View Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip. Abstract

Innate immune Galectin-7 specifically targets microbes that decorate themselves in blood group-like antigens. iScience. 2022 Jul 15; 25(7):104482. View Innate immune Galectin-7 specifically targets microbes that decorate themselves in blood group-like antigens. Abstract

The gut microbiome. Curr Biol. 2022 03 28; 32(6):R257-R264. View The gut microbiome. Abstract

Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite. Cell. 2022 02 03; 185(3):513-529.e21. View Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite. Abstract

Multi-kingdom ecological drivers of microbiota assembly in preterm infants. Nature. 2021 03; 591(7851):633-638. View Multi-kingdom ecological drivers of microbiota assembly in preterm infants. Abstract

Ecological rules for the assembly of microbiome communities. PLoS Biol. 2021 02; 19(2):e3001116. View Ecological rules for the assembly of microbiome communities. Abstract

Combined immunodeficiency due to a mutation in the ?1 subunit of the coat protein I complex. J Clin Invest. 2021 02 01; 131(3). View Combined immunodeficiency due to a mutation in the ?1 subunit of the coat protein I complex. Abstract

Stress ulcer prophylaxis versus placebo-a blinded randomized control trial to evaluate the safety of two strategies in critically ill infants with congenital heart disease (SUPPRESS-CHD). Trials. 2020 Jun 29; 21(1):590. View Stress ulcer prophylaxis versus placebo-a blinded randomized control trial to evaluate the safety of two strategies in critically ill infants with congenital heart disease (SUPPRESS-CHD). Abstract

Distribution and storage of inflammatory memory in barrier tissues. Nat Rev Immunol. 2020 05; 20(5):308-320. View Distribution and storage of inflammatory memory in barrier tissues. Abstract

Understanding Competition and Cooperation within the Mammalian Gut Microbiome. Curr Biol. 2019 06 03; 29(11):R538-R544. View Understanding Competition and Cooperation within the Mammalian Gut Microbiome. Abstract

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. BMC Biol. 2018 06 05; 16(1):62. View Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. Abstract

The evolution of the host microbiome as an ecosystem on a leash. Nature. 2017 08 02; 548(7665):43-51. View The evolution of the host microbiome as an ecosystem on a leash. Abstract

Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota. Nat Microbiol. 2016 07 25; 1(10):16125. View Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota. Abstract

The evolution of cooperation within the gut microbiota. Nature. 2016 05 12; 533(7602):255-9. View The evolution of cooperation within the gut microbiota. Abstract

Another Reason to Thank Mom: Gestational Effects of Microbiota Metabolites. Cell Host Microbe. 2016 Apr 13; 19(4):425-7. View Another Reason to Thank Mom: Gestational Effects of Microbiota Metabolites. Abstract

Host Selection of Microbiota via Differential Adhesion. Cell Host Microbe. 2016 Apr 13; 19(4):550-9. View Host Selection of Microbiota via Differential Adhesion. Abstract

The Regulation of Immunological Processes by Peripheral Neurons in Homeostasis and Disease. Trends Immunol. 2015 Oct; 36(10):578-604. View The Regulation of Immunological Processes by Peripheral Neurons in Homeostasis and Disease. Abstract

Analysis of gene-environment interactions in postnatal development of the mammalian intestine. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):1929-36. View Analysis of gene-environment interactions in postnatal development of the mammalian intestine. Abstract

Immunology: Starve a fever, feed the microbiota. Nature. 2014 Oct 30; 514(7524):576-7. View Immunology: Starve a fever, feed the microbiota. Abstract

An ecological network of polysaccharide utilization among human intestinal symbionts. Curr Biol. 2014 Jan 06; 24(1):40-49. View An ecological network of polysaccharide utilization among human intestinal symbionts. Abstract

Innate and adaptive immune connections in inflammatory bowel diseases. Curr Opin Gastroenterol. 2010 Nov; 26(6):572-7. View Innate and adaptive immune connections in inflammatory bowel diseases. Abstract

Toll-like receptors and cancer. Nat Rev Cancer. 2009 Jan; 9(1):57-63. View Toll-like receptors and cancer. Abstract

Innate immune recognition of the indigenous microbial flora. Mucosal Immunol. 2008 Nov; 1 Suppl 1:S10-4. View Innate immune recognition of the indigenous microbial flora. Abstract

Role of toll-like receptors in tissue repair and tumorigenesis. Biochemistry (Mosc). 2008 May; 73(5):555-61. View Role of toll-like receptors in tissue repair and tumorigenesis. Abstract

T cell responses to human endogenous retroviruses in HIV-1 infection. PLoS Pathog. 2007 Nov; 3(11):e165. View T cell responses to human endogenous retroviruses in HIV-1 infection. Abstract

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science. 2007 Jul 06; 317(5834):124-7. View Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Abstract

Prostaglandin-secreting cells: a portable first aid kit for tissue repair. J Clin Invest. 2007 Jan; 117(1):83-6. View Prostaglandin-secreting cells: a portable first aid kit for tissue repair. Abstract

Why cancer and inflammation? Yale J Biol Med. 2006 Dec; 79(3-4):123-30. View Why cancer and inflammation? Abstract

Retraction: Regulation of class II expression in monocytic cells after HIV-1 infection. J Immunol. 2006 Nov 01; 177(9):6561. View Retraction: Regulation of class II expression in monocytic cells after HIV-1 infection. Abstract

Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity. 2006 Aug; 25(2):319-29. View Role of toll-like receptors in spontaneous commensal-dependent colitis. Abstract

Role of the innate immune system and host-commensal mutualism. Curr Top Microbiol Immunol. 2006; 308:1-18. View Role of the innate immune system and host-commensal mutualism. Abstract

Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma. AIDS Res Hum Retroviruses. 2006 Jan; 22(1):52-6. View Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma. Abstract

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell. 2004 Jul 23; 118(2):229-41. View Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Abstract

Regulation of class II expression in monocytic cells after HIV-1 infection. J Immunol. 2001 Aug 15; 167(4):2331-42. View Regulation of class II expression in monocytic cells after HIV-1 infection. Abstract