Raynaud Phenomenon Pediatric Research and Clinical Trials

Research & Innovation

Though there is still no “cure” for Raynaud’s phenomenon, we’ve actually come a long way since Maurice Raynaud first described the condition in 1862. Today, physicians can call on a broad spectrum of drugs to treat Raynaud’s symptoms, while researchers continue to fill in the blanks for this baffling, if largely benign, condition.

Studies on pediatric Raynaud’s are rare, with Children’s Hospital Boston rheumatologists being among the handful of investigators. Peter Nigrovic, MD, and Robert Sundel, MD, recently coauthored a study of more than 100 Raynaud’s patients, ranging from infants to age 19, published in the journal Pediatrics. Among the study's findings:

  • Primary and secondary Raynaud’s tended to begin around the same age, roughly 12 or 13.
  • As with adult patients, the majority of the children referred to rheumatologists (about 70 percent) had the relatively harmless form of the condition, called primary Raynaud’s.
  • As with adult patients, antinuclear antibody (ANA) and nailfold capillary tests offered strong indicators of whether a child had secondary Raynaud’s.

Clinical trials

There are many ways in which your child might benefit from Children’s medical research program. Our doctors and scientists have made many breakthrough discoveries about diseases like polio and leukemia, and our ongoing innovative research continues to push the boundaries of the way pediatric medicine is practiced.

It’s possible that your child will be eligible to participate in one of Children’s current clinical trials. These studies are useful for a multitude of reasons: Some are designed to evaluate the effectiveness of a particular drug, treatment or therapy on a specific disease; others help doctors to better understand how and why certain conditions occur. At any given time, Children’s has hundreds of clinical trials under way.

And participation in any clinical trial is completely voluntary: We will take care to fully explain all elements of the treatment plan prior to the start of the trial, and you may remove your child from the medical study at any time.        

Search ongoing clinical trials at Children's.                      

Search the National Institutes of Health's list of clinical trials taking place around the world.

Clinical Trials

Find out more about the innovative clinical trials available at Children's. 

Children speak: What's it like to be a medical research subject?

 Watch this video on a day in the life of Children’s Clinical and Translational Study Unit.