Current Environment:

Selected Publications

  1. Tianxi Wang, Pingzhu Zhou, Xuemei Xie, Yohei Tomita, Steve Cho, Demetrios I. Tsirukis, Enton Lam, Hongbo R. Luo, Ye Sun. Myeloid lineage contributes to pathological choroidal neovascularization formation via SOCS3, EBioMedicine, 2021, 73, 103632. PMID: 34688035.  
  2. Tianxi Wang, Demetrios I. Tsirukis, Ye Sun. Targeting neuroinflammation in neurovascular retinal diseases. Frontiers in Pharmacology, 2020, 11, 234. PMID: 32210818. 
  3. Ye Sun, Chi-Hsiu Liu, Zhongxiao Wang, Steven S. Meng, Samuel B. Burnim, John Paul SanGiovanni, Theodore M. Kamenecka, Laura A. Solt, Jing Chen. RORa modulates Semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis. FASEB J., 2017,31 (10), 4492-4502. PMID: 28646017 
  4. Ye Sun, Zhiqiang Lin, Chi-Hsiu Liu, Yan Gong, Raffael Liegl, Thomas W. Fredrick, Steven S. Meng, Samuel B. Burnim, Zhongxiao Wang, James D. Akula, William T. Pu, Jing Chen, Lois E.H. Smith. Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos. Journal of Experimental Medicine, 2017, 214 (6), 1753-1767, PMID: 28465464 
  5. Ye Sun, Raffael Liegl, Yan Gong, Anima Bühler, Bertan Cakir, Steven S. Meng, Samuel B. Burnim, Chi-Hsiu Liu, Tristan Reuer, Peipei Zhang, JohannaM.Walz, Franziska Ludwig, Clemens Lange, Hansjürgen Agostini, Daniel Böhringer, Günther Schlunck, Lois E.H. Smith, Andreas Stahl. Sema3f Protects Against Subretinal Neovascularization In Vivo. EBioMedicine, 2017, 18, 281–287, PMID: 28373097 
  6. Jean-Sébastien Joyal, Ye Sun, Marin L. Gantner, Zhuo Shao, Lucy P. Evans, Nicholas Saba, Thomas Fredrick, Samuel Burnim, Jin Sung Kim, Gauri Patel, Aimee M. Juan, Christian G. Hurst, Colman J. Hatton, Zhenghao Cui, Kerry A. Pierce, Patrick Bherer, Edith Aguilar, Michael Powner, Kristis Vevis, Michel Boisvert, Zhongjie Fu, Émile Levy, Marcus Fruttiger, Alan Packard, Flavio A. Rezende, Bruno Maranda, Przemyslaw Sapieha, Jing Chen, Martin Friedlander, Clary B. Clish, Lois E.H. Smith. Retinal lipid and glucose metabolism dictate angiogenesis through lipid sensor Ffar1. Nature Medicine, 2016, 22(4), 439-45. PMID: 26974308 
  7. Ye Sun, Meihua Ju, Zhiqiang Lin, Thomas Fredrick, Lucy Evans, Katherine Tian, Nicholas Saba, Peyton Morss, William T Pu, Jing Chen, Andreas Stahl, Jean-Sébastien Joyal, Lois E.H. Smith. SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth. Sci. Signal, 2015, 8(395), ra94. PMID: 26396267 (Cover article) 
  8. Ye Sun, Chi-Hsiu Liu, John Paul SanGiovanni, Lucy Evans, Katherine Tian, Bing Zhang, Andreas Stahl, William T Pu, TM Kamenecka, Laura Solt, Jing Chen. Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation. Proc. Natl. Acad. Sci., 2015, 112(33), 10401-6. PMID: 26243880