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Dana-Farber/Boston Children's Cancer and Blood Disorders Center

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Medical School

Ludwig Maximilian University of Munich

2013, Bavaria, Germany

Graduate School

Ludwig Maximilian University of Munich

2014, Bavaria, Germany

Internship

Boston Combined Residency Program (BCRP)

2017, Boston, MA

Residency

Boston Combined Residency Program (BCRP)

2019, Boston, MA

Fellowship

Hematology and Oncology

Dana-Farber Cancer Institute/Boston Children's Hospital

2022, Boston, MA

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Publications

  1. ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance. Blood. 2025 May 07. View ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance. Abstract

  2. Umbilical Cord Blood Reduced Relapse but Increased Nonrelapse Mortality Compared to Matched Unrelated Donor Transplantation in Pediatric Acute Myeloid Leukemia With Active Disease: A CIBMTR 2008 to 2017 Analysis of Donor Source and Residual Disease. Transplant Cell Ther. 2025 Apr; 31(4):261.e1-261.e15. View Umbilical Cord Blood Reduced Relapse but Increased Nonrelapse Mortality Compared to Matched Unrelated Donor Transplantation in Pediatric Acute Myeloid Leukemia With Active Disease: A CIBMTR 2008 to 2017 Analysis of Donor Source and Residual Disease. Abstract

  3. Navigating Treatment Options and Communication in Relapsed Pediatric AML. Am Soc Clin Oncol Educ Book. 2024 Jun; 44(3):e438690. View Navigating Treatment Options and Communication in Relapsed Pediatric AML. Abstract

  4. Effects of Total Body Irradiation on Hematopoietic Cell Transplantation Outcomes in Pediatric Acute Myeloid Leukemia with Prior Central Nervous System Involvement. Transplant Cell Ther. 2024 Aug; 30(8):812.e1-812.e11. View Effects of Total Body Irradiation on Hematopoietic Cell Transplantation Outcomes in Pediatric Acute Myeloid Leukemia with Prior Central Nervous System Involvement. Abstract

  5. Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis. Mod Pathol. 2024 Jul; 37(7):100509. View Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis. Abstract

  6. Structural characterization of methylation-independent PP2A assembly guides alphafold2Multimer prediction of family-wide PP2A complexes. J Biol Chem. 2024 05; 300(5):107268. View Structural characterization of methylation-independent PP2A assembly guides alphafold2Multimer prediction of family-wide PP2A complexes. Abstract

  7. Pathophysiology of Acute Myeloid Leukemia. Acta Haematol. 2024; 147(2):229-246. View Pathophysiology of Acute Myeloid Leukemia. Abstract

  8. Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation. Clin Case Rep. 2023 Nov; 11(11):e8190. View Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation. Abstract

  9. Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry. J Am Chem Soc. 2023 Oct 11; 145(40):21937-21944. View Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry. Abstract

  10. Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders. Pediatr Blood Cancer. 2023 Jun 27; e30530. View Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders. Abstract

  11. The current landscape: Allogeneic hematopoietic stem cell transplant for acute lymphoblastic leukemia. Best Pract Res Clin Haematol. 2023 09; 36(3):101485. View The current landscape: Allogeneic hematopoietic stem cell transplant for acute lymphoblastic leukemia. Abstract

  12. Transient neonatal hemolytic anemia due to the novel gamma globin gene mutation HBG2:C.290T>C, p.Leu97Pro (hemoglobin Wareham). Pediatr Blood Cancer. 2023 01; 70(1):e30067. View Transient neonatal hemolytic anemia due to the novel gamma globin gene mutation HBG2:C.290T>C, p.Leu97Pro (hemoglobin Wareham). Abstract

  13. Comment on: Clinical, pathologic, and molecular features of inflammatory myofibroblastic tumors in children and adolescents: ROS1-fusion inflammatory myofibroblastic tumor: ROS1-fusion inflammatory myofibroblastic tumor. Pediatr Blood Cancer. 2023 02; 70(2):e29907. View Comment on: Clinical, pathologic, and molecular features of inflammatory myofibroblastic tumors in children and adolescents: ROS1-fusion inflammatory myofibroblastic tumor: ROS1-fusion inflammatory myofibroblastic tumor. Abstract

  14. Rapid next-generation sequencing aids in diagnosis of transient abnormal myelopoiesis in a phenotypically normal newborn. Blood Adv. 2022 05 10; 6(9):2893-2896. View Rapid next-generation sequencing aids in diagnosis of transient abnormal myelopoiesis in a phenotypically normal newborn. Abstract

  15. Molecular Characterization of Inflammatory Tumors Facilitates Initiation of Effective Therapy. Pediatrics. 2021 12 01; 148(6). View Molecular Characterization of Inflammatory Tumors Facilitates Initiation of Effective Therapy. Abstract

  16. Autoimmune hemolytic anemia complicated by parvovirus infection. Blood. 2021 02 25; 137(8):1130. View Autoimmune hemolytic anemia complicated by parvovirus infection. Abstract

  17. MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors. Cancer Res. 2019 05 01; 79(9):2404-2414. View MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors. Abstract

  18. Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. Neuron. 2017 Oct 11; 96(2):373-386.e6. View Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. Abstract

  19. Allosteric sensitization of proapoptotic BAX. Nat Chem Biol. 2017 Sep; 13(9):961-967. View Allosteric sensitization of proapoptotic BAX. Abstract

  20. Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting. Oncogene. 2017 04; 36(15):2184-2190. View Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting. Abstract

  21. Cellular Uptake and Ultrastructural Localization Underlie the Pro-apoptotic Activity of a Hydrocarbon-stapled BIM BH3 Peptide. ACS Chem Biol. 2015 Sep 18; 10(9):2149-57. View Cellular Uptake and Ultrastructural Localization Underlie the Pro-apoptotic Activity of a Hydrocarbon-stapled BIM BH3 Peptide. Abstract

  22. Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism. Mol Cell. 2015 Mar 05; 57(5):873-886. View Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism. Abstract

  23. Activation of DNA damage response by antitumor therapy counteracts the activity of vinca alkaloids. Anticancer Res. 2013 Dec; 33(12):5273-87. View Activation of DNA damage response by antitumor therapy counteracts the activity of vinca alkaloids. Abstract

  24. Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis. Cell Death Dis. 2013 Jun 06; 4:e661. View Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis. Abstract

  25. Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling. Cell Commun Signal. 2013 Apr 17; 11(1):27. View Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling. Abstract

  26. Enhanced anti-tumour effects of Vinca alkaloids given separately from cytostatic therapies. Br J Pharmacol. 2013 Apr; 168(7):1558-69. View Enhanced anti-tumour effects of Vinca alkaloids given separately from cytostatic therapies. Abstract

  27. NOXA as critical mediator for drug combinations in polychemotherapy. Cell Death Dis. 2012 Jun 21; 3:e327. View NOXA as critical mediator for drug combinations in polychemotherapy. Abstract

  28. Important role of caspase-8 for chemosensitivity of ALL cells. Clin Cancer Res. 2011 Dec 15; 17(24):7605-13. View Important role of caspase-8 for chemosensitivity of ALL cells. Abstract

  29. Optimized anti-tumor effects of anthracyclines plus Vinca alkaloids using a novel, mechanism-based application schedule. Blood. 2011 Dec 01; 118(23):6123-31. View Optimized anti-tumor effects of anthracyclines plus Vinca alkaloids using a novel, mechanism-based application schedule. Abstract

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Medical School

Ben Gurion University

2010, Beer Sheva, Israel

Residency

2017

Tel Aviv Medical Center

Pediatrics, Tel Aviv, Israel

Fellowship

Pediatric Hematology/Oncology

Tel Aviv Medical Center

2020, Tel Aviv, Israel

Fellowship

Pediatric Neuro-Oncology

Dana-Farber/Boston Children's Cancer and Blood Disorders Center

2021, Boston, MA

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Publications

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Undergraduate School

Harvard College

2011, Cambridge, MA

Graduate School

University of Oxford

2014, Oxford, United Kington

Medical School

Harvard Medical School

2018, Boston, MA

Internship

Internal Medicine

University of California, San Diego

2019, San Diego, CA

Residency

Radiation Oncology

Harvard Radiation Oncology Program

2023, Boston, MA

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Publications

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Graduate School

University of Minnesota College of Pharmacy

Minneapolis, MN

Medical School

University of Yamanashi

Chuo, Yamanashi, Japan

Residency

General Pediatrics

SUNY Downstate Medical Center

2018, Brooklyn, NY

Fellowship

Pediatric Hematology/Oncology

University of Minnesota

2021, Minneapolis, MN

Fellowship

Pediatric Stem Cell Transplantation

Boston Children's Hospital/Dana-Farber Cancer Institute

2022, Boston, MA

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Publications

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Undergraduate School

Brown University

2009, Providence, RI

Medical School

Johns Hopkins University School of Medicine

2015, Baltimore, MD

Internship

Pediatrics

Boston Combined Residency Program (BCRP)

2016, Boston, MA

Residency

Pediatrics

Boston Combined Residency Program (BCRP)

2018, Boston, MA

Fellowship

Pediatric Hematology and Oncology

Dana-Farber Cancer Institute/ Boston Children's Hospital

2021, Boston, MA

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Publications

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Medical School

Ain Shams University, Faculty of Medicine

2011, Cairo, Egypt

Internship

Internal Medicine

Ain Shams University, Faculty of Medicine

2012, Cairo, Egypt

Residency

Clinical Oncology/Nuclear Medicine

Ain Shams University, Faculty of Medicine

2015, Cairo, Egypt

Fellowship

Radiation Oncology

University of Texas MD Anderson Cancer Center

2019, Houston, TX

Fellowship

Radiation Oncology

Cleveland Clinic Taussig Cancer Institute

2020, Cleveland, OH

Fellowship

CNS Radiation Oncology

Brigham and Women’s Hospital

2022, Boston, MA

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Publications

Contact Dana-Farber/Boston Children's Cancer and Blood Disorders Center

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Medical School

Mount Sinai School of Medicine

New York, NY

Residency

Seattle Children's Hospital

Seattle, WA

Fellowship

Pediatric Hematology/Oncology

Seattle Children's Hospital

Seattle, WA

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Education

Medical School

Columbia College of Physicians & Surgeons

1993, New York, NY

Residency

Pediatrics

Babies and Children's Hospital, College of Physicians & Surgeons, Columbia University Medical Center

1997, New York, NY

Fellowship

Pediatric Hematology/Oncology

Memorial Sloan Kettering Cancer Center

2003, New York, NY

Dana-Farber/Boston Children's Cancer and Blood Disorders Center | Publications

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