Physicians | Education
Undergraduate School
University of Toronto
Toronto, Ontario, Canada
Undergraduate School
McGill University
Montreal, Quebec, Canada
Medical School
McGill University
Montreal, Quebec, Canada
Residency
Pediatrics
Schneider Children's Hospita
New Hyde Park, NY
Fellowship
Pediatrics
Hospital for Sick Children
Toronto, Ontario, Canada
Physicians | Publications
PR1P, a VEGF-stabilizing peptide, reduces injury and inflammation in acute lung injury and ulcerative colitis animal models. Front Immunol. 2023; 14:1168676. View PR1P, a VEGF-stabilizing peptide, reduces injury and inflammation in acute lung injury and ulcerative colitis animal models. Abstract
The Prominin-1-Derived Peptide Improves Cardiac Function Following Ischemia. Int J Mol Sci. 2021 May 13; 22(10). View The Prominin-1-Derived Peptide Improves Cardiac Function Following Ischemia. Abstract
Molecular mapping of transmembrane mechanotransduction through the ß1 integrin-CD98hc-TRPV4 axis. J Cell Sci. 2020 11 02; 133(20). View Molecular mapping of transmembrane mechanotransduction through the ß1 integrin-CD98hc-TRPV4 axis. Abstract
PR1P Stabilizes VEGF and Upregulates Its Signaling to Reduce Elastase-induced Murine Emphysema. Am J Respir Cell Mol Biol. 2020 10; 63(4):452-463. View PR1P Stabilizes VEGF and Upregulates Its Signaling to Reduce Elastase-induced Murine Emphysema. Abstract
AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage. APL Bioeng. 2019 Dec; 3(4):046103. View AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage. Abstract
Pregnancy and parental leave among obstetrics and gynecology residents: results of a nationwide survey of program directors. Am J Obstet Gynecol. 2018 08; 219(2):199.e1-199.e8. View Pregnancy and parental leave among obstetrics and gynecology residents: results of a nationwide survey of program directors. Abstract
A novel strategy to enhance angiogenesis in vivo using the small VEGF-binding peptide PR1P. Angiogenesis. 2017 Aug; 20(3):399-408. View A novel strategy to enhance angiogenesis in vivo using the small VEGF-binding peptide PR1P. Abstract
Prevention of ventilator-induced lung edema by inhalation of nanoparticles releasing ruthenium red. Am J Respir Cell Mol Biol. 2014 Jun; 50(6):1107-17. View Prevention of ventilator-induced lung edema by inhalation of nanoparticles releasing ruthenium red. Abstract
Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin a6ß1-ADAM17/tumor necrosis factor-a-converting enzyme (TACE) signaling pathway. J Biol Chem. 2013 Aug 30; 288(35):25646-25657. View Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin a6ß1-ADAM17/tumor necrosis factor-a-converting enzyme (TACE) signaling pathway. Abstract
A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Sci Transl Med. 2012 Nov 07; 4(159):159ra147. View A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Abstract
Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science. 2012 Aug 10; 337(6095):738-42. View Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Abstract
Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma. J Invest Dermatol. 2011 Dec; 131(12):2467-76. View Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma. Abstract
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integr Biol (Camb). 2010 Sep; 2(9):435-42. View Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Abstract
Reconstituting organ-level lung functions on a chip. Science. 2010 Jun 25; 328(5986):1662-8. View Reconstituting organ-level lung functions on a chip. Abstract
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface β1 integrins. . Integrative Biology (In Review). 2010.
Inhaled prophylactic nanotherapy for lung protection from Ventilator induced Lung Injury and Acute Respiratory Distress Syndrome (ARDS). 2010.
High-throughput Screen Identifies Rapamycin as a Drug to Suppress Self-Renewal and Vasculogenesis in Infantile Hemangioma. Journal of Cell Investigation (In Review). 2010.
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res. 2009 May 08; 104(9):1123-30. View TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Abstract
Wheeze detection in the pediatric intensive care unit: comparison among physician, nurses, respiratory therapists, and a computerized respiratory sound monitor. Respir Care. 2008 Oct; 53(10):1304-9. View Wheeze detection in the pediatric intensive care unit: comparison among physician, nurses, respiratory therapists, and a computerized respiratory sound monitor. Abstract
Rheological behavior of living cells is timescale-dependent. Biophys J. 2007 Oct 15; 93(8):L39-41. View Rheological behavior of living cells is timescale-dependent. Abstract
Tools to study cell mechanics and mechanotransduction. Methods Cell Biol. 2007; 83:443-72. View Tools to study cell mechanics and mechanotransduction. Abstract
Integrin-dependent force transmission to mechanosensitive ion channels. In: Hammill O, editors. Mechanosensitive Ion Channels. 2007; 59-85.
Tools to study cell mechanotransduction. In: Wang Y, Discher D., editors. Methods in Cell Biology. 2007; 441-472.
Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem. 2007 Jan 05; 282(1):467-77. View Alpha-actinin-4 is required for normal podocyte adhesion. Abstract
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci. 2006 Feb 01; 119(Pt 3):508-18. View Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. Abstract
Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. J Cell Biol. 2005 Dec 19; 171(6):1073-84. View Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. Abstract
Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry. Acta Biomater. 2005 May; 1(3):295-303. View Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry. Abstract
Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Biochem Biophys Res Commun. 2004 Jan 16; 313(3):758-64. View Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Abstract
SGMD: the Soybean Genomics and Microarray Database. Nucleic Acids Res. 2004 Jan 01; 32(Database issue):D398-400. View SGMD: the Soybean Genomics and Microarray Database. Abstract
Electromagnetic needles with submicron pole tip radii for nanomanipulation of biomolecules and living cells. Applied Physics Letters. 2004; 85:2968-2970..
Management of oxygenation in pediatric acute hypoxemic respiratory failure. Pediatr Pulmonol. 2001 Dec; 32(6):459-70. View Management of oxygenation in pediatric acute hypoxemic respiratory failure. Abstract
Role of the actin cytoskeleton in insulin action. Microsc Res Tech. 1999 Oct 15; 47(2):79-92. View Role of the actin cytoskeleton in insulin action. Abstract
Nucleotide sequence of 10 kilobases of rat tyrosine aminotransferase gene 5' flanking region. Nucleic Acids Res. 1989 Nov 11; 17(21):8877-8. View Nucleotide sequence of 10 kilobases of rat tyrosine aminotransferase gene 5' flanking region. Abstract