Current Environment: Production

Warning

Recall Alert

There is an antibacterial antibiotic recall. Read more

English | Education

Undergraduate School

Georgetown University

2020, Washington, DC

Graduate School

Boston College School of Social Work

2023, Boston, MA

English | Education

Undergraduate School

University of Pennsylvania

Philadelphia, PA

Graduate School

Yale University School of Nursing

Orange, CT

English | Education

Undergraduate School

University of Massachusetts at Amherst

Amherst, MA

Graduate School

Regis College

Weston, MA

English | Education

Graduate School

University of Minnesota College of Pharmacy

Minneapolis, MN

Medical School

University of Yamanashi

Chuo, Yamanashi, Japan

Residency

General Pediatrics

SUNY Downstate Medical Center

2018, Brooklyn, NY

Fellowship

Pediatric Hematology/Oncology

University of Minnesota

2021, Minneapolis, MN

Fellowship

Pediatric Stem Cell Transplantation

Boston Children's Hospital/Dana-Farber Cancer Institute

2022, Boston, MA

English | Publications

  1. Umbilical Cord Blood Reduced Relapse but Increased Nonrelapse Mortality Compared to Matched Unrelated Donor Transplantation in Pediatric Acute Myeloid Leukemia With Active Disease: A CIBMTR 2008 to 2017 Analysis of Donor Source and Residual Disease. Transplant Cell Ther. 2025 Apr; 31(4):261.e1-261.e15. View Umbilical Cord Blood Reduced Relapse but Increased Nonrelapse Mortality Compared to Matched Unrelated Donor Transplantation in Pediatric Acute Myeloid Leukemia With Active Disease: A CIBMTR 2008 to 2017 Analysis of Donor Source and Residual Disease. Abstract

  2. Effects of Total Body Irradiation on Hematopoietic Cell Transplantation Outcomes in Pediatric Acute Myeloid Leukemia with Prior Central Nervous System Involvement. Transplant Cell Ther. 2024 Aug; 30(8):812.e1-812.e11. View Effects of Total Body Irradiation on Hematopoietic Cell Transplantation Outcomes in Pediatric Acute Myeloid Leukemia with Prior Central Nervous System Involvement. Abstract

  3. Individualized rabbit anti-thymocyte globulin dosing in adult haploidentical hematopoietic cell transplantation with high-risk hematologic malignancy: Exposure-response analysis and population pharmacokinetics simulations. Am J Hematol. 2024 03; 99(3):387-395. View Individualized rabbit anti-thymocyte globulin dosing in adult haploidentical hematopoietic cell transplantation with high-risk hematologic malignancy: Exposure-response analysis and population pharmacokinetics simulations. Abstract

  4. Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events. Blood. 2023 08 24; 142(8):700-710. View Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events. Abstract

  5. Population Pharmacokinetic Model of Intravenous Busulfan in Hematopoietic Cell Transplantation: Systematic Review and Comparative Simulations. Clin Pharmacokinet. 2023 07; 62(7):955-968. View Population Pharmacokinetic Model of Intravenous Busulfan in Hematopoietic Cell Transplantation: Systematic Review and Comparative Simulations. Abstract

  6. Population Pharmacokinetics of Total Rabbit Anti-thymocyte Globulin in Non-obese Adult Patients Undergoing Hematopoietic Cell Transplantation for Hematologic Malignancy. Clin Pharmacokinet. 2023 08; 62(8):1081-1091. View Population Pharmacokinetics of Total Rabbit Anti-thymocyte Globulin in Non-obese Adult Patients Undergoing Hematopoietic Cell Transplantation for Hematologic Malignancy. Abstract

  7. T-cell depleted haploidentical hematopoietic cell transplantation for pediatric malignancy. Front Pediatr. 2022; 10:987220. View T-cell depleted haploidentical hematopoietic cell transplantation for pediatric malignancy. Abstract

  8. Influence of Renal Function on Phosphoramide Mustard Exposure: A Nonlinear Mixed-Effects Analysis. J Clin Pharmacol. 2023 01; 63(1):135-142. View Influence of Renal Function on Phosphoramide Mustard Exposure: A Nonlinear Mixed-Effects Analysis. Abstract

  9. Comparison of Dose Adjustment Strategies for Obesity in High-dose Cyclophosphamide Among Adult Hematopoietic Cell Transplantation Recipients: Pharmacokinetic Analysis. Transplant Cell Ther. 2022 12; 28(12):845.e1-845.e8. View Comparison of Dose Adjustment Strategies for Obesity in High-dose Cyclophosphamide Among Adult Hematopoietic Cell Transplantation Recipients: Pharmacokinetic Analysis. Abstract

  10. Therapeutic Leukapheresis in Pediatric Leukemia: Utilization Trend and Early Outcomes in a US Nationwide Cohort. J Pediatr Hematol Oncol. 2022 03 01; 44(2):47-53. View Therapeutic Leukapheresis in Pediatric Leukemia: Utilization Trend and Early Outcomes in a US Nationwide Cohort. Abstract

  11. Predictive Value of C-Reactive Protein and Albumin for Temporal Within-Individual Pharmacokinetic Variability of Voriconazole in Pediatric Patients Undergoing Hematopoietic Cell Transplantation. J Clin Pharmacol. 2022 07; 62(7):855-862. View Predictive Value of C-Reactive Protein and Albumin for Temporal Within-Individual Pharmacokinetic Variability of Voriconazole in Pediatric Patients Undergoing Hematopoietic Cell Transplantation. Abstract

  12. Effects of cyclophosphamide related genetic variants on clinical outcomes of adult hematopoietic cell transplant patients. Cancer Chemother Pharmacol. 2022 04; 89(4):543-549. View Effects of cyclophosphamide related genetic variants on clinical outcomes of adult hematopoietic cell transplant patients. Abstract

  13. Busulfan dose Recommendation in Inherited Metabolic Disorders: Population Pharmacokinetic Analysis. Transplant Cell Ther. 2022 02; 28(2):104.e1-104.e7. View Busulfan dose Recommendation in Inherited Metabolic Disorders: Population Pharmacokinetic Analysis. Abstract

  14. CYP2C19 Phenotype and Body Weight-Guided Voriconazole Initial Dose in Infants and Children after Hematopoietic Cell Transplantation. Antimicrob Agents Chemother. 2021 08 17; 65(9):e0062321. View CYP2C19 Phenotype and Body Weight-Guided Voriconazole Initial Dose in Infants and Children after Hematopoietic Cell Transplantation. Abstract

  15. CYP51A1 polymorphism and voriconazole-associated hepatotoxicity in children undergoing hematopoietic cell transplant. Int J Clin Pharmacol Ther. 2021 Jun; 59(6):442-446. View CYP51A1 polymorphism and voriconazole-associated hepatotoxicity in children undergoing hematopoietic cell transplant. Abstract

  16. Late-Onset Acute and Chronic Graft-versus-Host Disease in Children: Clinical Features and Response to Therapy. Transplant Cell Ther. 2021 08; 27(8):667.e1-667.e5. View Late-Onset Acute and Chronic Graft-versus-Host Disease in Children: Clinical Features and Response to Therapy. Abstract

  17. Higher Fludarabine and Cyclophosphamide Exposures Lead to Worse Outcomes in Reduced-Intensity Conditioning Hematopoietic Cell Transplantation for Adult Hematologic Malignancy. Transplant Cell Ther. 2021 09; 27(9):773.e1-773.e8. View Higher Fludarabine and Cyclophosphamide Exposures Lead to Worse Outcomes in Reduced-Intensity Conditioning Hematopoietic Cell Transplantation for Adult Hematologic Malignancy. Abstract

  18. Successful Rituximab Monotherapy in Advanced-stage, Epstein-Barr Virus-positive Diffuse Large B-Cell Lymphoma in an Adolescent With Systemic Juvenile Idiopathic Arthritis. J Pediatr Hematol Oncol. 2021 05 01; 43(4):e498-e500. View Successful Rituximab Monotherapy in Advanced-stage, Epstein-Barr Virus-positive Diffuse Large B-Cell Lymphoma in an Adolescent With Systemic Juvenile Idiopathic Arthritis. Abstract

  19. Outcomes of chronic graft-versus-host disease following matched sibling donor versus umbilical cord blood transplant. Bone Marrow Transplant. 2021 06; 56(6):1373-1380. View Outcomes of chronic graft-versus-host disease following matched sibling donor versus umbilical cord blood transplant. Abstract

  20. Impact of Obesity on Voriconazole Pharmacokinetics among Pediatric Hematopoietic Cell Transplant Recipients. Antimicrob Agents Chemother. 2020 11 17; 64(12). View Impact of Obesity on Voriconazole Pharmacokinetics among Pediatric Hematopoietic Cell Transplant Recipients. Abstract

  21. Pharmacogenomics of COVID-19 therapies. NPJ Genom Med. 2020; 5:35. View Pharmacogenomics of COVID-19 therapies. Abstract

  22. Safety and efficacy of gamma-secretase inhibitor nirogacestat (PF-03084014) in desmoid tumor: Report of four pediatric/young adult cases. Pediatr Blood Cancer. 2020 10; 67(10):e28636. View Safety and efficacy of gamma-secretase inhibitor nirogacestat (PF-03084014) in desmoid tumor: Report of four pediatric/young adult cases. Abstract

  23. In-hospital mortality of hematopoietic stem cell transplantation among children with nonmalignancies: A nationwide study in the United States from 2000 to 2012. Pediatr Blood Cancer. 2019 06; 66(6):e27626. View In-hospital mortality of hematopoietic stem cell transplantation among children with nonmalignancies: A nationwide study in the United States from 2000 to 2012. Abstract

  24. Factors Associated With Mechanical Ventilation Use in Children With Sickle Cell Disease and Acute Chest Syndrome. Pediatr Crit Care Med. 2018 09; 19(9):801-809. View Factors Associated With Mechanical Ventilation Use in Children With Sickle Cell Disease and Acute Chest Syndrome. Abstract

  25. Childhood leptospirosis in an industrialized country: Population-based study in Okinawa, Japan. PLoS Negl Trop Dis. 2018 03; 12(3):e0006294. View Childhood leptospirosis in an industrialized country: Population-based study in Okinawa, Japan. Abstract

  26. Acute chest syndrome among children hospitalized with vaso-occlusive crisis: A nationwide study in the United States. Pediatr Blood Cancer. 2018 03; 65(3). View Acute chest syndrome among children hospitalized with vaso-occlusive crisis: A nationwide study in the United States. Abstract

  27. 'Down-triage' for children with abnormal vital signs: evaluation of a new triage practice at a paediatric emergency department in Japan. Emerg Med J. 2016 Aug; 33(8):533-7. View 'Down-triage' for children with abnormal vital signs: evaluation of a new triage practice at a paediatric emergency department in Japan. Abstract

  28. Development of coronary artery lesions in indolent Kawasaki disease following initial spontaneous defervescence: a retrospective cohort study. Pediatr Rheumatol Online J. 2015 Nov 04; 13(1):44. View Development of coronary artery lesions in indolent Kawasaki disease following initial spontaneous defervescence: a retrospective cohort study. Abstract

English | Education

Undergraduate School

Indiana University

2004, Bloomington, IN

Graduate School

Harvard School of Public Health

2008, Boston, MA

Medical School

Yale School of Medicine

2009, New Haven, CT

Internship

General Surgery

Harvard Medical School/Beth Israel Deaconess Medical Center

2010, Boston, MA

Residency

Otolaryngology

Harvard Combined Program in Otolaryngology/Mass Eye and Ear

2014, Boston, MA

Fellowship

Neurotology

Harvard Combined Program in Otolaryngology/Mass Eye and Ear

2016, Boston, MA

English | Publications

English | Education

Undergraduate School

Boston College

2018, Chestnut Hill, MA

Graduate School

Simmons University

2023, Boston, MA

Talk to Lesley

If this is a medical emergency, please dial 9-1-1. This application should not be used in an emergency. This chat is being transmitted via a secure connection.

Hi! My name is Lesley. I am a virtual agent programmed to help you. If you would like to speak to a live agent, please call 617-355-6000.

I am unable to answer specific questions regarding your child's case, including appointments and conditions/diagnosis. Please contact your physician's office.

Quick links:

- MyChildrens Portal
- Global Services
- Find a Doctor
- Find a Location
- Programs and Services