Sara Trowbridge | Medical Services
Programs & Services
Languages
- English
Sara Trowbridge | Certifications
- American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
Sara Trowbridge | Professional History
Dr. Trowbridge is a neurologist and epileptologist at Boston Children's Hospital with board certification in neurology and special qualification in child neurology. She has additional fellowship training in epilepsy, clinical neurophysiology, and neurogenetics. Dr. Trowbridge obtained her Bachelor of Arts in Neurobiology from Harvard University and completed her MD degree through the Harvard-MIT Program in Health Sciences and Technology (HST) at Harvard Medical School. She conducted her residency training in child neurology and fellowship training at Boston Children's Hospital.
Her current research focuses on the molecular mechanisms underpinning neurodevelopmental disorders caused by variants in genes involved in chromatin regulation and gene transcription ("chromatinopathies").
Sara Trowbridge | Publications
FOS binding sites are a hub for the evolution of activity-dependent gene regulatory programs in human neurons. bioRxiv. 2025 Mar 31. View FOS binding sites are a hub for the evolution of activity-dependent gene regulatory programs in human neurons. Abstract
Sequence variants in HECTD1 result in a variable neurodevelopmental disorder. Am J Hum Genet. 2025 Mar 06; 112(3):537-553. View Sequence variants in HECTD1 result in a variable neurodevelopmental disorder. Abstract
Activity-induced MeCP2 phosphorylation regulates retinogeniculate synapse refinement. Proc Natl Acad Sci U S A. 2023 Oct 31; 120(44):e2310344120. View Activity-induced MeCP2 phosphorylation regulates retinogeniculate synapse refinement. Abstract
Effect of neonatal seizure burden and etiology on the long-term outcome: data from a randomized, controlled trial. Ann Child Neurol Soc. 2023 Mar; 1(1):53-65. View Effect of neonatal seizure burden and etiology on the long-term outcome: data from a randomized, controlled trial. Abstract
Early diagnosis and experimental treatment with fenfluramine via the Investigational New Drug mechanism in a boy with Dravet syndrome and recurrent status epilepticus. Epileptic Disord. 2021 Dec 01; 23(6):954-956. View Early diagnosis and experimental treatment with fenfluramine via the Investigational New Drug mechanism in a boy with Dravet syndrome and recurrent status epilepticus. Abstract
Increased electroencephalography connectivity precedes epileptic spasm onset in infants with tuberous sclerosis complex. Epilepsia. 2019 08; 60(8):1721-1732. View Increased electroencephalography connectivity precedes epileptic spasm onset in infants with tuberous sclerosis complex. Abstract
Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression. Cold Spring Harb Mol Case Stud. 2019 02; 5(1). View Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression. Abstract
Brain MRI abnormalities in patients with infantile spasms and Down syndrome. Epilepsy Behav. 2019 03; 92:57-60. View Brain MRI abnormalities in patients with infantile spasms and Down syndrome. Abstract
Aberrant development and plasticity of excitatory visual cortical networks in the absence of cpg15. J Neurosci. 2014 Mar 05; 34(10):3517-22. View Aberrant development and plasticity of excitatory visual cortical networks in the absence of cpg15. Abstract
Expression profiling of the RPE in zebrafish smarca4 mutant revealed altered signals that potentially affect RPE and retinal differentiation. Mol Vis. 2014; 20:56-72. View Expression profiling of the RPE in zebrafish smarca4 mutant revealed altered signals that potentially affect RPE and retinal differentiation. Abstract
Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. Eur J Neurosci. 2013 Sep; 38(5):2650-8. View Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. Abstract
Genetic models of serotonin (5-HT) depletion: what do they tell us about the developmental role of 5-HT? Anat Rec (Hoboken). 2011 Oct; 294(10):1615-23. View Genetic models of serotonin (5-HT) depletion: what do they tell us about the developmental role of 5-HT? Abstract