Steven Siegel | Education
Graduate School
University of Pennsylvania
2014, Philadelphia, PA
Medical School
University of Pennsylvania
2016, Philadelphia, PA
Residency
Pediatrics, Accelerated Research Pathway
Boston Children's Hospital
2018, Boston, MA
Fellowship
Pediatric Infectious Diseases
Boston Children's Hospital
2022, Boston, MA
Steven Siegel | Certifications
- American Board of Pediatrics (General)
Steven Siegel | Professional History
After completing combined MD and PhD training at the University of Pennsylvania, Dr. Siegel moved to Boston for pediatric residency at Boston Children's Hospital and Boston Medical Center in the accelerated research pathway. He then remained at Boston Children's Hospital for pediatric infectious diseases fellowship training, and joined the division faculty in 2022. He has a clinical interest in immunocompromised patients, particularly those who have undergone hematopoietic stem cell transplant (HCT). He conducts research in the laboratories of Drs. Seth Rakoff-Nahoum and Leslie Kean on the impact of the gut microbiome on outcomes in HCT patients.
Steven Siegel | Publications
Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking. PLoS Pathog. 2015 Jun; 11(6):e1005004. View Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking. Abstract
Mechanisms of Bacterial Colonization of the Respiratory Tract. Annu Rev Microbiol. 2015; 69:425-44. View Mechanisms of Bacterial Colonization of the Respiratory Tract. Abstract
TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model. PLoS Pathog. 2014 Aug; 10(8):e1004339. View TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model. Abstract
Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source. Cell Host Microbe. 2014 Jul 09; 16(1):55-67. View Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source. Abstract
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol. 2013 Jan; 87(1):257-72. View TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. Abstract
Activation of the mitogen-activated protein kinase, Slt2p, at bud tips blocks a late stage of endoplasmic reticulum inheritance in Saccharomyces cerevisiae. Mol Biol Cell. 2010 May 15; 21(10):1772-82. View Activation of the mitogen-activated protein kinase, Slt2p, at bud tips blocks a late stage of endoplasmic reticulum inheritance in Saccharomyces cerevisiae. Abstract
RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster. Mamm Genome. 2009 Nov-Dec; 20(11-12):749-57. View RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster. Abstract
Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow. J Immunol. 2008 Sep 15; 181(6):4004-9. View Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow. Abstract
Eosinophils from lineage-ablated Delta dblGATA bone marrow progenitors: the dblGATA enhancer in the promoter of GATA-1 is not essential for differentiation ex vivo. J Immunol. 2007 Aug 01; 179(3):1693-9. View Eosinophils from lineage-ablated Delta dblGATA bone marrow progenitors: the dblGATA enhancer in the promoter of GATA-1 is not essential for differentiation ex vivo. Abstract