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Summary

The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to noxious stimulation.

Conditions

Anesthesia, Pain

Recruitment Status

UNKNOWN

Eligibility Criteria

Inclusion Criteria:

* 12-30 years of age
* Structurally normal heart
* Right-handed
* English-speaking

Exclusion Criteria:

* Unable to cooperate or understand the study
* Neurologic disease
* Diabetes mellitus
* Syndrome of greater than minor severity.
* Smoker
* Scalp or hair does not permit sufficient optical light detection
* Unable to keep his/her head still for a period of 200 consecutive seconds

Intervention

Intervention Type

Intervention Name

DRUG

Remifentanil

DRUG

Normal saline

Phase

NA

Gender

ALL

Min Age

12 Years

Max Age

30 Years

Download Date

2021-01-07

Principal Investigator

N/A

Primary Contact Information

Rachel S Bernier, MPH

857-218-5348

rachel.bernier@childrens.harvard.edu

For more information on this trial, visit clinicaltrials.gov.

Contact

For more information and to contact the study team:

Assessing the Cortical Response to Noxious and Auditory Stimuli Using Near Infrared Spectroscopy in Subjects Under General Anesthesia NCT02703090 Rachel S Bernier, MPH 857-218-5348 rachel.bernier@childrens.harvard.edu

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