Current Environment: Production

Medical Services

Specialties

Programs & Services

Languages

  • English
  • Spanish

Education

Undergraduate School

Duke University

2008, Durham, NC

Medical School

University of Rochester School of Medicine and Dentistry

2012, Rochester, NY

Residency

University of Rochester Medical Center

2017, Rochester, NY

Fellowship

Boston Children's Hospital

2018, Boston, MA

Fellowship

Nicklaus Children's Hospital

2019, Miami, FL

Certifications

  • American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
  • American Board of Psychiatry and Neurology (Epilepsy)

Professional History

Dr. Tsuboyama completed her residency in child neurology at the University of Rochester Medical Center in Rochester, NY. She then completed a fellowship in Epilepsy/Clinical Neurophysiology at Boston Children's Hospital where she developed a particular interest in epilepsy surgery. To further her training in this area of interest, she spent one year at Nicklaus Children's Hospital in Miami, FL focusing on pediatric epilepsy surgery. She joined the department as a staff physician in August 2019 seeing patients with epilepsy in both the inpatient and outpatient settings.

In addition to her clinical work in pediatric epilepsy, Dr. Tsuboyama's research work is in part geared towards identifying the methods and factors that contribute to better epilepsy surgery outcomes. She also has a burgeoning interest in optimizing the use of medical devices such as those used for seizure detection and seizure treatments for people with various types of seizures.

Publications

  1. Analysis of DNA from brain tissue on stereo-EEG electrodes reveals mosaic epilepsy-related variants. Brain Commun. 2025; 7(2):fcaf113. View Abstract

  2. The neuropsychological profile of SSADH deficiency, a neurotransmitter disorder of GABA metabolism. Mol Genet Metab. 2025 Mar; 144(3):109051. View Abstract

  3. RORA-neurodevelopmental disorder: A unique triad of developmental disabilities, cerebellar anomalies, and myoclonic seizures. Genet Med. 2025 Apr; 27(4):101347. View Abstract

  4. Intralesional epileptiform activity in a fourth ventricular hamartoma associated with epileptic hemifacial spasm in a toddler: illustrative case. J Neurosurg Case Lessons. 2024 Jul 29; 8(5). View Abstract

  5. Analysis of DNA from brain tissue on stereo-EEG electrodes reveals mosaic epilepsy-related variants. medRxiv. 2024 Jul 22. View Abstract

  6. Predictive factors for seizure freedom after epilepsy surgery for pediatric low-grade tumors and focal cortical dysplasia. Epilepsy Behav Rep. 2024; 27:100680. View Abstract

  7. Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder. J Neurodev Disord. 2024 Apr 24; 16(1):21. View Abstract

  8. Clinical recommendations for conducting pediatric functional language and memory mapping during the phase I epilepsy presurgical workup. Clin Neuropsychol. 2024 Jul; 38(5):1060-1084. View Abstract

  9. Influence of extent and age at corpus callosotomy on seizure outcomes. A single center experience. Epilepsia Open. 2023 Dec; 8(4):1596-1601. View Abstract

  10. Shortened Motor Evoked Potential Latency in the Epileptic Hemisphere of Children With Focal Epilepsy. J Clin Neurophysiol. 2024 Sep 01; 41(6):530-536. View Abstract

  11. Focal drug-resistant temporal lobe epilepsy associated with an ipsilateral anterior choroidal artery aneurysm: illustrative case. J Neurosurg Case Lessons. 2023 Jun 26; 5(26). View Abstract

  12. Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency. Dev Med Child Neurol. 2023 12; 65(12):1596-1606. View Abstract

  13. The presence and severity of epilepsy coincide with reduced ?-aminobutyrate and cortical excitatory markers in succinic semialdehyde dehydrogenase deficiency. Epilepsia. 2023 06; 64(6):1516-1526. View Abstract

  14. Stereoelectroencephalography followed by combined electrode removal and MRI-guided laser interstitial thermal therapy or open resection: a single-center series in pediatric patients with medically refractory epilepsy. J Neurosurg Pediatr. 2023 03 01; 31(3):206-211. View Abstract

  15. Interictal Connectivity Revealed by Granger Analysis of Stereoelectroencephalography: Association With Ictal Onset Zone, Resection, and Outcome. Neurosurgery. 2022 10 01; 91(4):583-589. View Abstract

  16. Discrepant expressive language lateralization in children and adolescents with epilepsy. Ann Clin Transl Neurol. 2022 09; 9(9):1459-1464. View Abstract

  17. Clinical characteristics and outcomes after new-onset seizure among Zambian children with HIV during the antiretroviral therapy era. Epilepsia Open. 2022 06; 7(2):315-324. View Abstract

  18. Biomarkers Obtained by Transcranial Magnetic Stimulation in Neurodevelopmental Disorders. J Clin Neurophysiol. 2022 Feb 01; 39(2):135-148. View Abstract

  19. Transcranial Magnetic Stimulation in Succinic Semialdehyde Dehydrogenase Deficiency: A Measure of Maturational Trajectory of Cortical Excitability. J Child Neurol. 2021 11; 36(13-14):1169-1176. View Abstract

  20. CHL1 deletion is associated with cognitive and language disabilities - Case report and review of literature. Mol Genet Genomic Med. 2021 07; 9(7):e1725. View Abstract

  21. Subclinical seizures detected on intracranial EEG: Patient characteristics and impact on surgical outcome in a single pediatric epilepsy surgery center. Epilepsy Behav. 2021 08; 121(Pt A):108040. View Abstract

  22. Photoplethysmography: A measure for the function of the autonomic nervous system in focal impaired awareness seizures. Epilepsia. 2020 08; 61(8):1617-1626. View Abstract

  23. Review of Transcranial Magnetic Stimulation in Epilepsy. Clin Ther. 2020 07; 42(7):1155-1168. View Abstract

  24. Safety of rTMS in patients with intracranial metallic objects. Brain Stimul. 2020 May - Jun; 13(3):928-929. View Abstract

  25. Biomarkers Obtained by Transcranial Magnetic Stimulation of the Motor Cortex in Epilepsy. Front Integr Neurosci. 2019; 13:57. View Abstract

  26. Assessing the localization accuracy and clinical utility of electric and magnetic source imaging in children with epilepsy. Clin Neurophysiol. 2019 04; 130(4):491-504. View Abstract

  27. Neurologic Complications of Acute Posterior Multifocal Placoid Pigment Epitheliopathy: A Case Series of 4 Patients. Neurohospitalist. 2018 Jul; 8(3):146-151. View Abstract

  28. Devices for Ambulatory Monitoring of Sleep-Associated Disorders in Children with Neurological Diseases. Children (Basel). 2017 Dec 25; 5(1). View Abstract

  29. Using patient characteristics to predict usefulness of abdominal computed tomography in children. Hosp Pediatr. 2013 Jul; 3(3):226-32. View Abstract

One of the many reasons I was drawn to child neurology was because of the relationships I get to build with both the patients and their families. Their strength and resilience inspire and motivate me to do my best to help them any way that I can, and to work towards finding better and more comprehensive therapies for all children with epilepsy.

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