Current Environment: Production

Medical Services

Specialties

Programs & Services

Languages

  • English
  • Dutch

Education

Medical School

Faculty of Medicine, Catholic University of Leuven

2002, Leuven, Belgium

Residency

Adult Neurology

VU University Medical Center Amsterdam

2003, Amsterdam, Netherlands

Residency

Adult Neurology

Haga Teaching Hospital

2006, Houten, Netherlands

Fellowship

Epilepsy & Clinical Neurophysiology

Boston Children's Hospital

2007, Boston, MA

Residency

Child Neurology

Boston Children's Hospital

2010, Boston, MA

Internship

Pediatrics

Boston Combined Residency Program (BCRP)

2011, Boston, MA

Fellowship

Neuroimaging at Neurology (ABPN Neuroscience Track)

Boston Children's Hospital

2012, Boston, MA

Certifications

  • American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
  • American Board of Psychiatry and Neurology (Epilepsy)

Professional History

Jurriaan M. Peters MD, PhD, is an Associate Professor of Neurology at Harvard Medical School, and is a pediatric epileptologist with additional expertise in clinical neurophysiology and neuroimaging. He earned his MD at the Catholic University of Leuven, Belgium, and his PhD at the University of Utrecht. He did his Child Neurology training and Clinical Neurophysiology fellowship training at Boston Children’s Hospital.

Throughout his career he has operated on the boundary between clinical care and cutting edge novel technologies. He is the principal epileptologist at the Multidisciplinary Tuberous Sclerosis Clinic at Boston Children’s Hospital. His research in the Laboratory of Translational Neuroimaging and in the Computational Radiology Laboratory focuses on novel MRI and EEG modeling techniques in the localization of the seizure onset zone in children with medically refractory epilepsy, on how focal lesions give rise to a generalized epileptic encephalopathy; and on early medical and surgical treatment of epilepsy to mitigate detrimental effects on neurodevelopment.

Publications

  1. Exploring proposed recommendations for immediate-use seizure medication: Treating both cluster and prolonged seizures with diazepam nasal spray. Epilepsia Open. 2025 May 10. View Abstract

  2. Prevalence, Characteristics, and Management of Pancreatic Tumors Among Children With Tuberous Sclerosis Complex. J Pediatr Surg. 2025 Apr 24; 60(7):162339. View Abstract

  3. Accumulated seizure burden predicts neurodevelopmental outcome at 36?months of age in patients with tuberous sclerosis complex. Epilepsia. 2025 Jan; 66(1):117-133. View Abstract

  4. Association of earlier surgery with improved postoperative language development in children with tuberous sclerosis complex. J Neurosurg Pediatr. 2024 Oct 01; 34(4):384-392. View Abstract

  5. Drug-Resistant Epilepsy in Tuberous Sclerosis Complex Is Associated With TSC2 Genotype: More Findings From the Preventing Epilepsy Using Vigatrin (PREVeNT) Trial. Pediatr Neurol. 2024 Oct; 159:62-71. View Abstract

  6. Short-Term Impact of Seizures and Mitigation Opportunities. Curr Neurol Neurosci Rep. 2024 Aug; 24(8):303-314. View Abstract

  7. Publisher Correction to: Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex. J Autism Dev Disord. 2024 Mar; 54(3):1232. View Abstract

  8. Taking a Newer, Faster, Intranasal Route: A Narrative Review of Transitioning to a Less-Invasive Rescue Treatment for Seizure Clusters. Patient Prefer Adherence. 2024; 18:383-389. View Abstract

  9. Analyses of patients who self-administered diazepam nasal spray for acute treatment of seizure clusters. Epilepsy Behav Rep. 2024; 25:100644. View Abstract

  10. Comment on: Failure to use new breakthrough treatments for epilepsy. Epilepsia. 2023 11; 64(11):3109-3110. View Abstract

  11. Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurol. 2023 09 01; 80(9):891-902. View Abstract

  12. Early Treatment with Vigabatrin Does Not Decrease Focal Seizures or Improve Cognition in Tuberous Sclerosis Complex: The PREVeNT Trial. Ann Neurol. 2023 Aug 28. View Abstract

  13. Acute seizure therapies in people with epilepsy: Fact or fiction? A U.S. Perspective. Epilepsy Behav Rep. 2023; 23:100612. View Abstract

  14. Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex. J Autism Dev Disord. 2024 Aug; 54(8):3155-3175. View Abstract

  15. Concomitant cannabidiol does not impact safety and effectiveness of diazepam nasal spray for seizure clusters: Post hoc analysis of a phase 3 safety study. Epilepsy Behav. 2023 Jul; 144:109248. View Abstract

  16. Focal epilepsies: Update on diagnosis and classification. Epileptic Disord. 2023 Feb; 25(1):1-17. View Abstract

  17. Treatment-Resistant Epilepsy and Tuberous Sclerosis Complex: Treatment, Maintenance, and Future Directions. Neuropsychiatr Dis Treat. 2023; 19:733-748. View Abstract

  18. Aluminum Thin Film Nanostructure Traces in Pediatric EEG Net for MRI and CT Artifact Reduction. Sensors (Basel). 2023 Mar 31; 23(7). View Abstract

  19. Epilepsy Severity Is Associated With Head Circumference and Growth Rate in Infants With Tuberous Sclerosis Complex. Pediatr Neurol. 2023 07; 144:26-32. View Abstract

  20. The nose has it: Opportunities and challenges for intranasal drug administration for neurologic conditions including seizure clusters. Epilepsy Behav Rep. 2023; 21:100581. View Abstract

  21. Tubers Affecting the Fusiform Face Area Are Associated with Autism Diagnosis. Ann Neurol. 2023 03; 93(3):577-590. View Abstract

  22. Significant improvements in SEIzure interVAL (time between seizure clusters) across time in patients treated with diazepam nasal spray as intermittent rescue therapy for seizure clusters. Epilepsia. 2022 10; 63(10):2684-2693. View Abstract

  23. Limited utility of structural MRI to identify the epileptogenic zone in young children with tuberous sclerosis. J Neuroimaging. 2022 09; 32(5):991-1000. View Abstract

  24. Reply to "Added value of high-resolution electrical source imaging of ictal activity in children with structural focal epilepsy". Clin Neurophysiol. 2022 08; 140:254-255. View Abstract

  25. Virtual implantation using conventional scalp EEG delineates seizure onset and predicts surgical outcome in children with epilepsy. Clin Neurophysiol. 2022 07; 139:49-57. View Abstract

  26. Comment on "Intranasal midazolam versus intravenous/rectal benzodiazepines for acute seizure control in children: A systematic review and meta-analysis". Epilepsy Behav. 2022 03; 128:108550. View Abstract

  27. Infantile Hemiconvulsion-Hemiplegia and Epilepsy (IHHE) in a boy with tuberous sclerosis complex. Epilepsy Behav Rep. 2021; 16:100473. View Abstract

  28. Startle Epilepsy Triggered By Maternal Cough. Neuropediatrics. 2021 08; 52(4):341-342. View Abstract

  29. Convolutional neural networks to identify malformations of cortical development: A feasibility study. Seizure. 2021 Oct; 91:81-90. View Abstract

  30. Source imaging of seizure onset predicts surgical outcome in pediatric epilepsy. Clin Neurophysiol. 2021 07; 132(7):1622-1635. View Abstract

  31. High-Density EEG in Current Clinical Practice and Opportunities for the Future. J Clin Neurophysiol. 2021 Mar 01; 38(2):112-123. View Abstract

  32. Tuber Locations Associated with Infantile Spasms Map to a Common Brain Network. Ann Neurol. 2021 04; 89(4):726-739. View Abstract

  33. Hippocampal Involvement With Vigabatrin-Related MRI Signal Abnormalities in Patients With Infantile Spasms: A Novel Finding. J Child Neurol. 2021 06; 36(7):575-582. View Abstract

  34. Patient-Specific Sensor Registration for Electrical Source Imaging Using a Deformable Head Model. IEEE Trans Biomed Eng. 2021 01; 68(1):267-275. View Abstract

  35. LEARNING TO DETECT BRAIN LESIONS FROM NOISY ANNOTATIONS. Proc IEEE Int Symp Biomed Imaging. 2020 Apr; 2020:1910-1914. View Abstract

  36. A structural brain network of genetic vulnerability to psychiatric illness. Mol Psychiatry. 2021 06; 26(6):2089-2100. View Abstract

  37. Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex. PLoS One. 2020; 15(4):e0232376. View Abstract

  38. The Connectivity Fingerprint of the Fusiform Gyrus Captures the Risk of Developing Autism in Infants with Tuberous Sclerosis Complex. Cereb Cortex. 2020 04 14; 30(4):2199-2214. View Abstract

  39. Pilot Study of Neurodevelopmental Impact of Early Epilepsy Surgery in Tuberous Sclerosis Complex. Pediatr Neurol. 2020 08; 109:39-46. View Abstract

  40. EEG Spectral Features in Sleep of Autism Spectrum Disorders in Children with Tuberous Sclerosis Complex. J Autism Dev Disord. 2020 Mar; 50(3):916-923. View Abstract

  41. Update on Drug Management of Refractory Epilepsy in Tuberous Sclerosis Complex. Paediatr Drugs. 2020 Feb; 22(1):73-84. View Abstract

  42. Clinical Reasoning: A 6-week-old infant with migrating focal seizures. Neurology. 2020 01 28; 94(4):178-183. View Abstract

  43. Lesion-Constrained Electrical Source Imaging: A Novel Approach in Epilepsy Surgery for Tuberous Sclerosis Complex. J Clin Neurophysiol. 2020 Jan; 37(1):79-86. View Abstract

  44. Early white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder. J Neurodev Disord. 2019 12 16; 11(1):36. View Abstract

  45. Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational study. Epilepsia. 2019 12; 60(12):2428-2436. View Abstract

  46. Reproducibility of Structural and Diffusion Tensor Imaging in the TACERN Multi-Center Study. Front Integr Neurosci. 2019; 13:24. View Abstract

  47. Resting-State fMRI Networks in Children with Tuberous Sclerosis Complex. J Neuroimaging. 2019 11; 29(6):750-759. View Abstract

  48. Increased electroencephalography connectivity precedes epileptic spasm onset in infants with tuberous sclerosis complex. Epilepsia. 2019 08; 60(8):1721-1732. View Abstract

  49. The Evolution of Subclinical Seizures in Children With Tuberous Sclerosis Complex. J Child Neurol. 2019 10; 34(12):770-777. View Abstract

  50. White matter mean diffusivity correlates with myelination in tuberous sclerosis complex. Ann Clin Transl Neurol. 2019 07; 6(7):1178-1190. View Abstract

  51. Seizure Prediction Models in the Neonatal Intensive Care Unit. J Clin Neurophysiol. 2019 May; 36(3):186-194. View Abstract

  52. Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism. Ann Neurol. 2019 06; 85(6):921-926. View Abstract

  53. Multi-Resolution Graph Based Volumetric Cortical Basis Functions From Local Anatomic Features. IEEE Trans Biomed Eng. 2019 12; 66(12):3381-3392. View Abstract

  54. Assessing the localization accuracy and clinical utility of electric and magnetic source imaging in children with epilepsy. Clin Neurophysiol. 2019 04; 130(4):491-504. View Abstract

  55. Longitudinal Effects of Everolimus on White Matter Diffusion in Tuberous Sclerosis Complex. Pediatr Neurol. 2019 01; 90:24-30. View Abstract

  56. High vigabatrin dosage is associated with lower risk of infantile spasms relapse among children with tuberous sclerosis complex. Epilepsy Res. 2018 12; 148:1-7. View Abstract

  57. Corpus Callosum White Matter Diffusivity Reflects Cumulative Neurological Comorbidity in Tuberous Sclerosis Complex. Cereb Cortex. 2018 10 01; 28(10):3665-3672. View Abstract

  58. Surgical resection of ripple onset predicts outcome in pediatric epilepsy. Ann Neurol. 2018 09; 84(3):331-346. View Abstract

  59. A Comparison of Point and Complete Electrode Models in a Finite Difference Model of Invasive Electrode Measurements. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:4677-4680. View Abstract

  60. Presurgical language fMRI: Technical practices in epilepsy surgical planning. Hum Brain Mapp. 2018 10; 39(10):4032-4042. View Abstract

  61. Somatic SLC35A2 variants in the brain are associated with intractable neocortical epilepsy. Ann Neurol. 2018 06; 83(6):1133-1146. View Abstract

  62. Vigabatrin for Epileptic Spasms and Tonic Seizures in Tuberous Sclerosis Complex. J Child Neurol. 2018 07; 33(8):519-524. View Abstract

  63. Detailed Magnetic Resonance Imaging (MRI) Analysis in Infantile Spasms. J Child Neurol. 2018 05; 33(6):405-412. View Abstract

  64. Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning. Hum Brain Mapp. 2018 07; 39(7):2777-2785. View Abstract

  65. Response to clobazam in continuous spike-wave during sleep. Dev Med Child Neurol. 2018 03; 60(3):283-289. View Abstract

  66. Presentation and Diagnosis of Tuberous Sclerosis Complex in Infants. Pediatrics. 2017 Dec; 140(6). View Abstract

  67. Localization of stereo-electroencephalography signals using a finite difference complete electrode model. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:3600-3603. View Abstract

  68. Systemic Manifestations in Pyridox(am)ine 5'-Phosphate Oxidase Deficiency. Pediatr Neurol. 2017 Nov; 76:47-53. View Abstract

  69. Reduced thalamic volume in patients with Electrical Status Epilepticus in Sleep. Epilepsy Res. 2017 02; 130:74-80. View Abstract

  70. Dynamic Electrical Source Imaging (DESI) of Seizures and Interictal Epileptic Discharges Without Ensemble Averaging. IEEE Trans Med Imaging. 2017 01; 36(1):98-110. View Abstract

  71. Extensions to a manifold learning framework for time-series analysis on dynamic manifolds in bioelectric signals. Phys Rev E. 2016 04; 93(4):042218. View Abstract

  72. A pediatric epilepsy diagnostic tool for use in resource-limited settings: A pilot study. Epilepsy Behav. 2016 06; 59:57-61. View Abstract

  73. SCN2A-Related Early-Onset Epileptic Encephalopathy Responsive to Phenobarbital. J Pediatr Epilepsy. 2016 Mar; 5(1):42-46. View Abstract

  74. Improved fidelity of brain microstructure mapping from single-shell diffusion MRI. Med Image Anal. 2015 Dec; 26(1):268-86. View Abstract

  75. Tubers are neither static nor discrete: Evidence from serial diffusion tensor imaging. Neurology. 2015 Nov 03; 85(18):1536-45. View Abstract

  76. Clinical Electroencephalographic Biomarker for Impending Epilepsy in Asymptomatic Tuberous Sclerosis Complex Infants. Pediatr Neurol. 2016 Jan; 54:29-34. View Abstract

  77. Tuberous Sclerosis: A New Frontier in Targeted Treatment of Autism. Neurotherapeutics. 2015 Jul; 12(3):572-83. View Abstract

  78. Teaching video neuroimages: nonepileptic myoclonus in a neonate following severe hypoxic-ischemic injury. Neurology. 2015 Mar 24; 84(12):e90. View Abstract

  79. Altered Structural Brain Networks in Tuberous Sclerosis Complex. Cereb Cortex. 2016 May; 26(5):2046-58. View Abstract

  80. Localization of sleep spindles, k-complexes, and vertex waves with subdural electrodes in children. J Clin Neurophysiol. 2014 Aug; 31(4):367-74. View Abstract

  81. Safety and retention rate of rufinamide in 300 patients: a single pediatric epilepsy center experience. Epilepsia. 2014 Aug; 55(8):1235-44. View Abstract

  82. Treatment for continuous spikes and waves during sleep (CSWS): survey on treatment choices in North America. Epilepsia. 2014 Jul; 55(7):1099-108. View Abstract

  83. Clobazam: effect on frequency of seizures and safety profile in different subgroups of children with epilepsy. Pediatr Neurol. 2014 Jul; 51(1):60-6. View Abstract

  84. A fully Bayesian inference framework for population studies of the brain microstructure. Med Image Comput Comput Assist Interv. 2014; 17(Pt 1):25-32. View Abstract

  85. Insult to injury: transient encephalopathy in a brain-injured adolescent. J Paediatr Child Health. 2014 May; 50(5):411-4. View Abstract

  86. Clinical value of magnetoencephalographic spike propagation represented by spatiotemporal source analysis: correlation with surgical outcome. Epilepsy Res. 2014 Feb; 108(2):280-8. View Abstract

  87. A mathematical framework for the registration and analysis of multi-fascicle models for population studies of the brain microstructure. IEEE Trans Med Imaging. 2014 Feb; 33(2):504-17. View Abstract

  88. Long-term response to high-dose diazepam treatment in continuous spikes and waves during sleep. Pediatr Neurol. 2013 Sep; 49(3):163-170.e4. View Abstract

  89. Diffusion tensor imaging and related techniques in tuberous sclerosis complex: review and future directions. Future Neurol. 2013 Sep; 8(5):583-597. View Abstract

  90. Continuous Spikes and Waves during Sleep: Electroclinical Presentation and Suggestions for Management. Epilepsy Res Treat. 2013; 2013:583531. View Abstract

  91. [The brain functional network of children with autism: redundancy and disconnection]. Med Sci (Paris). 2013 Jun-Jul; 29(6-7):567-9. View Abstract

  92. Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. Int J Comput Assist Radiol Surg. 2014 Jan; 9(1):91-105. View Abstract

  93. Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity. BMC Med. 2013 Feb 27; 11:54. View Abstract

  94. A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex. Pediatr Neurol. 2013 Feb; 48(2):105-10. View Abstract

  95. Automated quantification of spikes. Epilepsy Behav. 2013 Feb; 26(2):143-52. View Abstract

  96. Whole Brain Group Network Analysis Using Network Bias and Variance Parameters. 2012; (in press):Proc IEEE Int Conf Biom Imag.

  97. Electrical status epilepticus in sleep: clinical presentation and pathophysiology. Pediatr Neurol. 2012 Dec; 47(6):390-410. View Abstract

  98. The tower of Babel: survey on concepts and terminology in electrical status epilepticus in sleep and continuous spikes and waves during sleep in North America. Epilepsia. 2013 Apr; 54(4):741-50. View Abstract

  99. Impaired language pathways in tuberous sclerosis complex patients with autism spectrum disorders. Cereb Cortex. 2013 Jul; 23(7):1526-32. View Abstract

  100. Clinical staging and electroencephalographic evolution of continuous spikes and waves during sleep. Epilepsia. 2012 Jul; 53(7):1185-95. View Abstract

  101. Short-term response of sleep-potentiated spiking to high-dose diazepam in electric status epilepticus during sleep. Pediatr Neurol. 2012 May; 46(5):312-8. View Abstract

  102. WHOLE BRAIN GROUP NETWORK ANALYSIS USING NETWORK BIAS AND VARIANCE PARAMETERS. Proc IEEE Int Symp Biomed Imaging. 2012 May; 2012:1511-1514. View Abstract

  103. Early thalamic lesions in patients with sleep-potentiated epileptiform activity. Neurology. 2012 May 29; 78(22):1721-7. View Abstract

  104. Patients with electrical status epilepticus in sleep share similar clinical features regardless of their focal or generalized sleep potentiation of epileptiform activity. J Child Neurol. 2013 Jan; 28(1):83-9. View Abstract

  105. Behavioral measures and EEG monitoring using the Brain Symmetry Index during the Wada test in children. Epilepsy Behav. 2012 Mar; 23(3):247-53. View Abstract

  106. Good outcome with early empiric treatment of neural larva migrans due to Baylisascaris procyonis. Pediatrics. 2012 Mar; 129(3):e806-11. View Abstract

  107. Loss of white matter microstructural integrity is associated with adverse neurological outcome in tuberous sclerosis complex. Acad Radiol. 2012 Jan; 19(1):17-25. View Abstract

  108. Registration and analysis of white matter group differences with a multi-fiber model. Med Image Comput Comput Assist Interv. 2012; 15(Pt 3):313-20. View Abstract

  109. Spinal cord involvement in a child with raccoon roundworm (Baylisascaris procyonis) meningoencephalitis. Pediatr Radiol. 2012 Mar; 42(3):369-73. View Abstract

  110. Continuous spike and waves during sleep and electrical status epilepticus in sleep. J Clin Neurophysiol. 2011 Apr; 28(2):154-64. View Abstract

  111. Guillain-Barré syndrome in a child with pain: lessons learned from a late diagnosis. Acta Paediatr. 2010 Oct; 99(10):1589-91. View Abstract

  112. High-dose intravenous levetiracetam for acute seizure exacerbation in children with intractable epilepsy. Epilepsia. 2010 Jul; 51(7):1319-22. View Abstract

  113. Rapid resolution of diffusion weighted MRI abnormality in a patient with a stuttering stroke. BMJ Case Rep. 2010; 2010. View Abstract

  114. Picture of the month--quiz case. Moyamoya disease. Arch Pediatr Adolesc Med. 2009 Feb; 163(2):179-80. View Abstract

  115. Intracranial penetration of a halo pin causing an epileptic seizure. J Bone Joint Surg Br. 2006 Dec; 88(12):1654-5. View Abstract

  116. Tijdschr Neurol Neurochir. Neuromonitoring met on-line qEEG tijdens carotisendarteriectomie: ervaringen met de Brain Symmetry Index. 2005; 106(4):143-150.

  117. A brain symmetry index (BSI) for online EEG monitoring in carotid endarterectomy. Clin Neurophysiol. 2004 May; 115(5):1189-94. View Abstract

  118. Event-related correlations in learning impaired children during A hybrid go/no-go choice reaction visual-motor task. Clin Electroencephalogr. 2003 Jul; 34(3):99-109. View Abstract

  119. Tijdschr Neurol Neurochir. Continue EEG-monitoring op de intensive care. 2003; 104(5):276-282.

  120. Population study of benign rolandic epilepsy: is treatment needed? Neurology. 2001 Aug 14; 57(3):537-9. View Abstract

It is amazing that science can be applied to humans, so it is less abstract than mathematics or physics. But it is exactly the clinical application of novel technologies and innovations that can drive patient care forward and change the field.

Clinically, I am amazed by how hard work and a sustained effort in care can make a difference, not on a group level, but for individual patients. I believe strongly in “putting up a good fight”, as it often pays off. In that, I find that forming a diagnostic and therapeutic alliance with parents, and if needed with colleagues, can really positively impact the lives of patients and their families.

BESbswy
BESbswy