Current Environment: Production

Medical Services

Specialties

Programs & Services

Languages

  • English

Education

Undergraduate School

University of Pennsylvania

1997, Philadelphia, PA

Medical School

University of Massachusetts Medical School

2004, Worcester, MA

Internship

Pediatrics

Yale New Haven Children's Hospital

2004, New Haven, CT

Residency

Pediatrics

Yale New Haven Children's Hospital

2007, New Haven, CT

Fellowship

Respiratory Diseases

Boston Children's Hospital

2007, Boston, MA

Certifications

  • American Board of Pediatrics (Pulmonology)

Professional History

Dr. Gaffin serves as an expert for the Department of Medicine for Boston Children's Hospital Precision Medicine Service. For more information about the Precision Medicine Service please visit bostonchildrens.org/precisionmed.

Publications

  1. Evaluating the Impact of the COVID-19 Pandemic on Pediatric Asthma Incidence. J Allergy Clin Immunol Pract. 2025 May 14. View Abstract

  2. Cost-effectiveness of school integrated pest management and air filtration in students with asthma. Allergy Asthma Proc. 2025 May 01; 46(3):257-266. View Abstract

  3. The Frequency and Potential Implications of HFE Genetic Variants in Children With Cystic Fibrosis. Pediatr Pulmonol. 2025 Mar; 60(3):e71042. View Abstract

  4. Biomarkers of inflammation associated with radon exposure in the School Inner-City Asthma Study (SICAS). J Allergy Clin Immunol. 2025 Feb 07. View Abstract

  5. Health-related quality of life in children with bronchopulmonary dysplasia: examining agreement between child self-report and parent proxy. Eur J Pediatr. 2024 Nov 21; 184(1):36. View Abstract

  6. Impact of acid blocker therapy on growth, gut microbiome, and lung disease in young children with cystic fibrosis. J Pediatr Gastroenterol Nutr. 2024 Dec; 79(6):1124-1133. View Abstract

  7. Ambient smoke exposure and indoor air quality in eastern Massachusetts during the 2023 wildfire season. J Air Waste Manag Assoc. 2024 Nov; 74(11):820-827. View Abstract

  8. Research Priorities in Pediatric Asthma Morbidity: Addressing the Impacts of Systemic Racism on Children with Asthma in the United States. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2024 Oct; 21(10):1349-1364. View Abstract

  9. Urinary biomarkers of environmental exposures and asthma morbidity in a school inner city asthma study. Int J Hyg Environ Health. 2024 Sep; 262:114430. View Abstract

  10. Evaluation of dupilumab on the disease burden in children and adolescents with atopic dermatitis: A population-based cohort study. Allergy. 2024 Oct; 79(10):2748-2758. View Abstract

  11. Initiatives to improve lung and sleep health in children: Delphi consensus from the pediatrics, pulmonary, and sleep conference. Pediatr Pulmonol. 2024 Nov; 59(11):2800-2808. View Abstract

  12. Asthma and Sleep-disordered Breathing Overlap in School-aged Children. Ann Am Thorac Soc. 2024 Jun; 21(6):986-989. View Abstract

  13. Comparison of home-based spirometry and oscillometry measurements in school-age children with bronchopulmonary dysplasia. Pediatr Pulmonol. 2024 Oct; 59(10):2589-2596. View Abstract

  14. The effects of urban green space and road proximity to indoor traffic-related PM2.5, NO2, and BC exposure in inner-city schools. J Expo Sci Environ Epidemiol. 2024 Sep; 34(5):745-752. View Abstract

  15. Recent Insights into the Environmental Determinants of Childhood Asthma. Curr Allergy Asthma Rep. 2024 05; 24(5):253-260. View Abstract

  16. Solar and geomagnetic activity impacts children with asthma. J Allergy Clin Immunol Pract. 2024 04; 12(4):1077-1079.e1. View Abstract

  17. Improving Asthma Action Plan Completion Rates across Five Divisions in an Academic Children's Hospital. Pediatr Qual Saf. 2023 Nov-Dec; 8(6):e700. View Abstract

  18. Defining and Promoting Pediatric Pulmonary Health: Assessing Lung Function and Structure. Pediatrics. 2023 09 01; 152(Suppl 2). View Abstract

  19. Measuring adherence in paediatric asthma: Integrating pharmacy data into clinical care. J Eval Clin Pract. 2024 02; 30(1):137-139. View Abstract

  20. Comparison of Pneumotachometer and Portable Digital Turbine Spirometry for Field-Based Assessment: An Air Quality, Environment, and Respiratory Outcomes in Bronchopulmonary Dysplasia Study. Pediatr Allergy Immunol Pulmonol. 2023 09; 36(3):115-118. View Abstract

  21. Is chronotype linked with adherence to the Mediterranean diet among adolescents? The EHDLA study. Pediatr Res. 2023 Dec; 94(6):2070-2076. View Abstract

  22. Health-Related Qualities of Life in School-Aged Children with Bronchopulmonary Dysplasia. J Pediatr. 2023 10; 261:113548. View Abstract

  23. Effect of radon exposure on asthma morbidity in the School Inner-City Asthma study. Pediatr Pulmonol. 2023 Jul; 58(7):2042-2049. View Abstract

  24. Socioeconomic determinants of asthma health. Curr Opin Pediatr. 2023 06 01; 35(3):337-343. View Abstract

  25. Environment and the development of severe asthma in inner city population. Curr Opin Allergy Clin Immunol. 2023 04 01; 23(2):179-184. View Abstract

  26. Air pollution and childhood asthma. Curr Opin Allergy Clin Immunol. 2023 04 01; 23(2):100-110. View Abstract

  27. Environmental radon and childhood asthma. Pediatr Pulmonol. 2022 12; 57(12):3165-3168. View Abstract

  28. Determinants of lung function across childhood in the Severe Asthma Research Program (SARP) 3. J Allergy Clin Immunol. 2023 01; 151(1):138-146.e9. View Abstract

  29. Mouse allergen levels in schools over the decade. J Allergy Clin Immunol Pract. 2022 11; 10(11):3024-3025. View Abstract

  30. Pediatric EVALI in the Age of COVID-19/MIS-C: Diagnostic Considerations. Hosp Pediatr. 2022 07 01; 12(7):e249-e254. View Abstract

  31. Defining and identifying early-onset lung disease in cystic fibrosis with cumulative clinical characteristics. Pediatr Pulmonol. 2022 10; 57(10):2363-2373. View Abstract

  32. Factors Influencing Classroom Exposures to Fine Particles, Black Carbon, and Nitrogen Dioxide in Inner-City Schools and Their Implications for Indoor Air Quality. Environ Health Perspect. 2022 04; 130(4):47005. View Abstract

  33. HEPA filtration intervention in classrooms may improve some students' asthma. J Asthma. 2023 03; 60(3):479-486. View Abstract

  34. CENTER-IT: a novel methodology for adapting multi-level interventions using the Consolidated Framework for Implementation Research-a case example of a school-supervised asthma intervention. Implement Sci Commun. 2022 Mar 26; 3(1):33. View Abstract

  35. The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children. J Allergy Clin Immunol Pract. 2022 02; 10(2):397-408. View Abstract

  36. The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions. J Allergy Clin Immunol. 2022 02; 149(2):488-516.e9. View Abstract

  37. Issues affecting young people with asthma through the transition period to adult care. Paediatr Respir Rev. 2022 Mar; 41:30-39. View Abstract

  38. Effect of School Integrated Pest Management or Classroom Air Filter Purifiers on Asthma Symptoms in Students With Active Asthma: A Randomized Clinical Trial. JAMA. 2021 09 07; 326(9):839-850. View Abstract

  39. Thoracic Multidetector Computed Tomography Findings of Dedicator of Cytokinesis 8 Deficiency in Children. J Thorac Imaging. 2021 Sep 01; 36(5):304-309. View Abstract

  40. Reconstructing Phenotypes in Recurrent Severe Wheeze in Young Children. Am J Respir Crit Care Med. 2021 09 01; 204(5):495-496. View Abstract

  41. Predictors of successful mouse allergen reduction in inner-city homes of children with asthma. J Allergy Clin Immunol Pract. 2021 11; 9(11):4159-4161.e2. View Abstract

  42. Development and Validation of the Asthma Exacerbation Risk Score Using Claims Data. Acad Pediatr. 2022 Jan-Feb; 22(1):47-54. View Abstract

  43. Associations of Snoring and Asthma Morbidity in the School Inner-City Asthma Study. J Allergy Clin Immunol Pract. 2021 10; 9(10):3679-3685.e1. View Abstract

  44. Air quality, Environment and Respiratory Outcomes in Bronchopulmonary Dysplasia, the AERO-BPD cohort study: design and adaptation during the SARS-CoV-2 pandemic. BMJ Open Respir Res. 2021 06; 8(1). View Abstract

  45. Lung function trajectories in children with post-prematurity respiratory disease: identifying risk factors for abnormal growth. Respir Res. 2021 May 10; 22(1):143. View Abstract

  46. Impact of the COVID-19 Pandemic on Pediatric Emergency Department Use for Asthma. Ann Am Thorac Soc. 2021 04; 18(4):717-719. View Abstract

  47. Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma. Am J Respir Crit Care Med. 2021 04 01; 203(7):841-852. View Abstract

  48. Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma. J Asthma. 2022 06; 59(6):1148-1156. View Abstract

  49. Geography, generalisability, and susceptibility in clinical trials. Lancet Respir Med. 2021 04; 9(4):330-332. View Abstract

  50. Validation of the Hospital Asthma Severity Score (HASS) in children ages 2-18 years old. J Asthma. 2022 Feb; 59(2):315-324. View Abstract

  51. The Respiratory Risks of Ambient/Outdoor Air Pollution. Clin Chest Med. 2020 12; 41(4):809-824. View Abstract

  52. Preventing asthma in high risk kids (PARK) with omalizumab: Design, rationale, methods, lessons learned and adaptation. Contemp Clin Trials. 2021 01; 100:106228. View Abstract

  53. Asthma control and psychological health in pediatric severe asthma. Pediatr Pulmonol. 2021 01; 56(1):42-48. View Abstract

  54. Asthma Prevalence and Mold Levels in US Northeastern Schools. J Allergy Clin Immunol Pract. 2021 03; 9(3):1312-1318. View Abstract

  55. Differential Effect of School-Based Pollution Exposure in Children With Asthma Born Prematurely. Chest. 2020 10; 158(4):1361-1363. View Abstract

  56. Supernumerary intrathoracic rib, a rare congenital anomaly: Case report and review of the literature. Pediatr Pulmonol. 2020 06; 55(6):1487-1489. View Abstract

  57. Obesity may enhance the adverse effects of NO2 exposure in urban schools on asthma symptoms in children. J Allergy Clin Immunol. 2020 10; 146(4):813-820.e2. View Abstract

  58. Proximity to major roadways and asthma symptoms in the School Inner-City Asthma Study. J Allergy Clin Immunol. 2020 01; 145(1):119-126.e4. View Abstract

  59. Classroom indoor PM2.5 sources and exposures in inner-city schools. Environ Int. 2019 10; 131:104968. View Abstract

  60. Screening and Counseling for Alcohol Use in Adolescents With Chronic Medical Conditions in the Ambulatory Setting. J Adolesc Health. 2019 06; 64(6):804-806. View Abstract

  61. Pediatrician Attitudes toward Digital Voice Assistant Technology Use in Clinical Practice. Appl Clin Inform. 2019 03; 10(2):286-294. View Abstract

  62. Association between fungal spore exposure in inner-city schools and asthma morbidity. Ann Allergy Asthma Immunol. 2019 06; 122(6):610-615.e1. View Abstract

  63. Asthma and Corticosteroid Responses in Childhood and Adult Asthma. Clin Chest Med. 2019 03; 40(1):163-177. View Abstract

  64. Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019 05; 143(5):1934-1937.e4. View Abstract

  65. Question 3: Can we diagnose asthma in children under the age of 5?years? Paediatr Respir Rev. 2019 Feb; 29:25-30. View Abstract

  66. Bronchodilator Use for Acute Chest Syndrome Among Large Pediatric Hospitals in North America. Clin Pediatr (Phila). 2018 12; 57(14):1630-1637. View Abstract

  67. Transcutaneous CO-oximetry differentiates asthma exacerbation and convalescence in children. J Allergy Clin Immunol. 2018 08; 142(2):676-678.e5. View Abstract

  68. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med. 2018 Apr 10; 18(1):58. View Abstract

  69. A Practical Approach to Severe Asthma in Children. Ann Am Thorac Soc. 2018 04; 15(4):399-408. View Abstract

  70. The classroom microbiome and asthma morbidity in children attending 3 inner-city schools. J Allergy Clin Immunol. 2018 06; 141(6):2311-2313. View Abstract

  71. Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations. N Engl J Med. 2018 Mar 08; 378(10):891-901. View Abstract

  72. Advances in environmental and occupational disorders in 2016. J Allergy Clin Immunol. 2017 Dec; 140(6):1683-1692. View Abstract

  73. Nitrogen dioxide exposure in school classrooms of inner-city children with asthma. J Allergy Clin Immunol. 2018 06; 141(6):2249-2255.e2. View Abstract

  74. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):545-554.e4. View Abstract

  75. Adherence and stress in a population of inner-city children with asthma. Pediatr Allergy Immunol. 2017 09; 28(6):610-612. View Abstract

  76. ATS Core Curriculum 2017: Part II. Pediatric Pulmonary Medicine. Ann Am Thorac Soc. 2017 08; 14(Suppl_2):S165-S181. View Abstract

  77. The School Inner-City Asthma Intervention Study: Design, rationale, methods, and lessons learned. Contemp Clin Trials. 2017 09; 60:14-23. View Abstract

  78. Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. Am J Respir Crit Care Med. 2017 06 01; 195(11):1439-1448. View Abstract

  79. Utilization of a patient-centered asthma passport tool in a subspecialty clinic. J Asthma. 2018 02; 55(2):180-187. View Abstract

  80. Caregiver stress among inner-city school children with asthma. J Allergy Clin Immunol Pract. 2017 Jul - Aug; 5(4):1132-1134.e3. View Abstract

  81. Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2017 02 01; 195(3):302-313. View Abstract

  82. Association Between Allergen Exposure in Inner-City Schools and Asthma Morbidity Among Students. JAMA Pediatr. 2017 01 01; 171(1):31-38. View Abstract

  83. The Calculated Risk of Childhood Asthma From Severe Bronchiolitis. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):97-98. View Abstract

  84. Comparison of treatment modalities for inpatient asthma exacerbations among US pediatric hospitals. J Allergy Clin Immunol Pract. 2017 May - Jun; 5(3):855-857.e1. View Abstract

  85. Individualized therapy for persistent asthma in young children. J Allergy Clin Immunol. 2016 12; 138(6):1608-1618.e12. View Abstract

  86. School Environmental Intervention to Reduce Particulate Pollutant Exposures for Children with Asthma. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):154-159.e3. View Abstract

  87. Modeling indoor particulate exposures in inner-city school classrooms. J Expo Sci Environ Epidemiol. 2017 09; 27(5):451-457. View Abstract

  88. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18; 375(7):619-30. View Abstract

  89. Utility of a portable hand-held forced expiratory volume in 1 second meter for monitoring asthma in an inner-city school setting. Ann Allergy Asthma Immunol. 2016 09; 117(3):323-4. View Abstract

  90. Pediatric Rhinosinusitis. Curr Treat Options Allergy. 2016 Sep; 3(3):268-281. View Abstract

  91. A Screening Tool for Assessing Alcohol Use Risk among Medically Vulnerable Youth. PLoS One. 2016; 11(5):e0156240. View Abstract

  92. Association of FEF25%-75% and bronchodilator reversibility with asthma control and asthma morbidity in inner-city children with asthma. Ann Allergy Asthma Immunol. 2016 07; 117(1):97-9. View Abstract

  93. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA. 2015 Nov 17; 314(19):2034-2044. View Abstract

  94. School Endotoxin Exposure and Asthma Morbidity in Inner-city Children. Chest. 2015 Nov; 148(5):1251-1258. View Abstract

  95. Postnatal environmental tobacco smoke exposure is associated with objective markers of atopy in preschool-aged children. Evid Based Med. 2015 Dec; 20(6):219. View Abstract

  96. Black and Hispanic perceptions of asthma medication in the School Inner-City Asthma Study. Ann Allergy Asthma Immunol. 2015 Jun; 114(6):533-4. View Abstract

  97. Association between allergic sensitization and exhaled nitric oxide in children in the School Inner-City Asthma Study. Ann Allergy Asthma Immunol. 2015 Mar; 114(3):256-257.e1. View Abstract

  98. Child with atopic dermatitis. Ann Allergy Asthma Immunol. 2015 Jan; 114(1):6-11. View Abstract

  99. Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine. Environ Health Perspect. 2015 Jan; 123(1):6-20. View Abstract

  100. Reprint of: Perinatal and early childhood environmental factors influencing allergic asthma immunopathogenesis. Int Immunopharmacol. 2014 Nov; 23(1):337-46. View Abstract

  101. Perinatal and early childhood environmental factors influencing allergic asthma immunopathogenesis. Int Immunopharmacol. 2014 Sep; 22(1):21-30. View Abstract

  102. The indoor environment and inner-city childhood asthma. Asian Pac J Allergy Immunol. 2014 Jun; 32(2):103-10. View Abstract

  103. Social disadvantage and asthma control in children. Paediatr Respir Rev. 2014 Sep; 15(3):256-62; quiz 262-3. View Abstract

  104. Allergens on desktop surfaces in preschools and elementary schools of urban children with asthma. Allergy. 2014 Jul; 69(7):960-963. View Abstract

  105. Perceived neighborhood safety and asthma morbidity in the school inner-city asthma study. Pediatr Pulmonol. 2015 Jan; 50(1):17-24. View Abstract

  106. ß-2 adrenergic receptor gene methylation is associated with decreased asthma severity in inner-city schoolchildren: asthma and rhinitis. Clin Exp Allergy. 2014; 44(5):681-9. View Abstract

  107. Beta-2-Adrenergic Receptor Methylation Influences Asthma Phenotype in The School Inner City Asthma Study. Receptors Clin Investig. 2014; 1(1). View Abstract

  108. Exposures to molds in school classrooms of children with asthma. Pediatr Allergy Immunol. 2013 Nov; 24(7):697-703. View Abstract

  109. Rethinking the prevalence of exercise-induced bronchoconstriction in patients with asthma. Ann Allergy Asthma Immunol. 2013 Dec; 111(6):567-8. View Abstract

  110. Food allergy and increased asthma morbidity in a School-based Inner-City Asthma Study. J Allergy Clin Immunol Pract. 2013 Sep-Oct; 1(5):479-84. View Abstract

  111. Predictors of indoor exposure to mouse allergen in inner-city elementary schools. Ann Allergy Asthma Immunol. 2013 Oct; 111(4):299-301.e1. View Abstract

  112. The utility of forced expiratory flow between 25% and 75% of vital capacity in predicting childhood asthma morbidity and severity. J Asthma. 2012 Aug; 49(6):586-92. View Abstract

  113. Allergens in urban schools and homes of children with asthma. Pediatr Allergy Immunol. 2012 Sep; 23(6):543-9. View Abstract

  114. Role of specific IgE and skin-prick testing in predicting food challenge results to baked egg. Allergy Asthma Proc. 2012 May-Jun; 33(3):275-81. View Abstract

  115. Effect of cat and daycare exposures on the risk of asthma in children with atopic dermatitis. Allergy Asthma Proc. 2012 May-Jun; 33(3):282-8. View Abstract

  116. Endotoxin exposure in inner-city schools and homes of children with asthma. Ann Allergy Asthma Immunol. 2012 Jun; 108(6):418-22. View Abstract

  117. Parental response to written eczema action plans in children with eczema. Arch Dermatol. 2012 Mar; 148(3):391-2. View Abstract

  118. The school inner-city asthma study: design, methods, and lessons learned. J Asthma. 2011 Dec; 48(10):1007-14. View Abstract

  119. Agreement between parent and student responses to an asthma and allergy questionnaire in a diverse, inner-city elementary school population. Ann Allergy Asthma Immunol. 2011 Oct; 107(4):371-3. View Abstract

  120. Research abstracts presented at the Fall Meeting of the New England Society of Allergy, October 23-24, 2010, Woodstock, Vermont. Allergy Asthma Proc. 2011 Jan 01; 32(1):80-81. View Abstract

  121. Tree nut allergy, egg allergy, and asthma in children. Clin Pediatr (Phila). 2011 Feb; 50(2):133-9. View Abstract

  122. The effect of prophylactic palivizumab on recurrent wheezing in children with an atopic family history. J Allergy Clin Immunol. 2011 Jan; 127(1):292-3; author reply 293. View Abstract

  123. Clinically useful spirometry in preschool-aged children: evaluation of the 2007 American Thoracic Society Guidelines. J Asthma. 2010 Sep; 47(7):762-7. View Abstract

  124. The role of indoor allergens in the development of asthma. Curr Opin Allergy Clin Immunol. 2009 Apr; 9(2):128-35. View Abstract

  125. Peanut Allergy is Associated with Increased Asthma Prevalence in Food Allergic Children. AAAAI. 2009.

  126. Montelukast as Monotherapy for Pediatric Asthma. MP Med Prakt Pediatr. 2009; 3(63):20-23. View Abstract

  127. Picture of the month. Blueberry muffin baby (extramedullary hematopoiesis) due to congenital cytomegalovirus infection. Arch Pediatr Adolesc Med. 2007 Nov; 161(11):1102-3. View Abstract

  128. Sleep. Yale Curriculum in Primary Care. 2007.

  129. Sleep. Yale Curriculum in Primary Care. 2006.
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