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Siobhan Case | Certifications

  • American Board of Internal Medicine (General)
  • American Board of Pediatrics (General)

Siobhan Case | Professional History

I am an attending physician in pediatric and adult rheumatology working at Boston Children’s Hospital and Brigham and Women’s Hospital. I am especially interested in helping patients with childhood-onset rheumatic disease learn self-management skills and smoothly transition into adult care.
I went to college at Stanford University, where I graduated with University Distinction and Honors in Human Biology. I then went to Yale School of Medicine where I completed both an MD and a Masters in Health Science as part of a Doris Duke Clinical Research fellowship.

For medical training, I came to Boston Children’s Hospital and Brigham and Women’s Hospital for a combined residency in Internal Medicine and Pediatrics (Med-Peds), followed by a combined fellowship in Pediatric and Adult Rheumatology. Throughout fellowship I worked at the Center for Adults with Pediatric-onset Rheumatic Illness (CAPRI), a clinic specifically designed to help transition young adults to adult rheumatology, and I have continued my work in the CAPRI Clinic as an attending. My research has focused on disparities in care, especially for patients with systemic lupus

Siobhan Case | Publications

  1. Sex Differences in B Cells From the Joints of Children With Oligoarticular Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2025 Mar 17. View Sex Differences in B Cells From the Joints of Children With Oligoarticular Juvenile Idiopathic Arthritis. Abstract

  2. Earlier vs. later time period of COVID-19 infection and emergent autoimmune signs, symptoms, and serologies. J Autoimmun. 2024 09; 148:103299. View Earlier vs. later time period of COVID-19 infection and emergent autoimmune signs, symptoms, and serologies. Abstract

  3. Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus. Semin Arthritis Rheum. 2024 Oct; 68:152516. View Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus. Abstract

  4. Barriers, Facilitators, and Preferences for Mental Health Services Among Patients With Systemic Lupus Erythematosus: A Qualitative Study. Arthritis Care Res (Hoboken). 2024 07; 76(7):914-925. View Barriers, Facilitators, and Preferences for Mental Health Services Among Patients With Systemic Lupus Erythematosus: A Qualitative Study. Abstract

  5. Incidence and Risk Factors for Eosinophilia and Lung Disease in Biologic-Exposed Children With Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2023 10; 75(10):2063-2072. View Incidence and Risk Factors for Eosinophilia and Lung Disease in Biologic-Exposed Children With Systemic Juvenile Idiopathic Arthritis. Abstract

  6. Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. Front Immunol. 2022; 13:1068399. View Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. Abstract

  7. The link between post-traumatic stress disorder and systemic lupus erythematosus. Brain Behav Immun. 2023 Feb; 108:292-301. View The link between post-traumatic stress disorder and systemic lupus erythematosus. Abstract

  8. Joint-Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis. Arthritis Rheumatol. 2022 11; 74(11):1851-1858. View Joint-Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis. Abstract

  9. Posttraumatic Stress Disorder and Risk of Systemic Lupus Erythematosus Among Medicaid Recipients. Arthritis Care Res (Hoboken). 2023 01; 75(1):174-179. View Posttraumatic Stress Disorder and Risk of Systemic Lupus Erythematosus Among Medicaid Recipients. Abstract

  10. Recognizing Racial Bias and Promoting Diversity in the Rheumatology Workforce. Arthritis Rheumatol. 2022 09; 74(9):1459-1463. View Recognizing Racial Bias and Promoting Diversity in the Rheumatology Workforce. Abstract

  11. An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. J Rheumatol. 2022 Sep; 49(9):1042-1051. View An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. Abstract

  12. Implications of Evolving Disease Classification for Drug Approval in Juvenile Idiopathic Arthritis. Paediatr Drugs. 2022 May; 24(3):185-191. View Implications of Evolving Disease Classification for Drug Approval in Juvenile Idiopathic Arthritis. Abstract

  13. Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. JCI Insight. 2021 09 22; 6(18). View Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. Abstract

  14. COVID-19 in Pediatrics. Rheum Dis Clin North Am. 2021 11; 47(4):797-811. View COVID-19 in Pediatrics. Abstract

  15. Patient experiences and strategies for coping with SLE: A qualitative study. Lupus. 2021 Aug; 30(9):1405-1414. View Patient experiences and strategies for coping with SLE: A qualitative study. Abstract

  16. Interleukin-6 Blockade With Tocilizumab in Anakinra-Refractory Febrile Infection-Related Epilepsy Syndrome (FIRES). Child Neurol Open. 2020 Jan-Dec; 7:2329048X20979253. View Interleukin-6 Blockade With Tocilizumab in Anakinra-Refractory Febrile Infection-Related Epilepsy Syndrome (FIRES). Abstract

  17. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. JCI Insight. 2020 03 26; 5(6). View Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. Abstract

  18. Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Ann Rheum Dis. 2020 02; 79(2):225-231. View Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Abstract

  19. Predictors of disability in a childhood-onset systemic lupus erythematosus cohort: results from the CARRA Legacy Registry. Lupus. 2018 Mar; 27(3):494-500. View Predictors of disability in a childhood-onset systemic lupus erythematosus cohort: results from the CARRA Legacy Registry. Abstract

  20. Older Adults' Recognition of Trade-Offs in Healthcare Decision-Making. J Am Geriatr Soc. 2015 Aug; 63(8):1658-62. View Older Adults' Recognition of Trade-Offs in Healthcare Decision-Making. Abstract

  21. Relationship between universal health outcome priorities and willingness to take medication for primary prevention of myocardial infarction. J Am Geriatr Soc. 2014 Sep; 62(9):1753-8. View Relationship between universal health outcome priorities and willingness to take medication for primary prevention of myocardial infarction. Abstract

  22. Considering the balance: development of a scale to assess patient views on trade-offs in competing health outcomes. J Am Geriatr Soc. 2013 Aug; 61(8):1331-6. View Considering the balance: development of a scale to assess patient views on trade-offs in competing health outcomes. Abstract

  23. How to ask: older adults' preferred tools in health outcome prioritization. Patient Educ Couns. 2013 Apr; 91(1):29-36. View How to ask: older adults' preferred tools in health outcome prioritization. Abstract

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