Current Environment: Production

Medical Services

Specialties

Programs & Services

Languages

  • English

Education

Medical School

St. Luke's College of Medicine

2007, Manila, Philippines

Residency

Donald & Barbara Zucker School of Medicine at Hofstra University

2015, Hempstead, NY

Fellowship

Children's Hospital of Philadelphia

2017, Philadelphia, PA

Fellowship

Boston Children's Hospital

2018, Boston, MA

Certifications

  • American Board of Pathology (Anatomic Clinical Pathology)
  • American Board of Pathology (Pediatric)

Publications

  1. Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy. Nat Commun. 2025 Apr 16; 16(1):3604. View Abstract

  2. Anomalous Origin of the Right Coronary Artery From Pulmonary Trunk in a Hypoplastic Left Heart Syndrome With 15q11.2 BP1-BP2 Microdeletion: A Novel Association. Pediatr Dev Pathol. 2025 Mar-Apr; 28(2):133-136. View Abstract

  3. Cross-modal contrastive learning for unified placenta analysis using photographs. Patterns (N Y). 2024 Dec 13; 5(12):101097. View Abstract

  4. Placental-Heart Axis: An Evolutionary Perspective. Int J Mol Sci. 2024 Oct 18; 25(20). View Abstract

  5. Maternal Vascular Malperfusion and Anatomic Cord Abnormalities Are Prevalent in Pregnancies With Fetal Congenital Heart Disease. Prenat Diagn. 2024 Aug 30. View Abstract

  6. High-resolution three-dimensional atlas of congenital heart defects based on micro-CT images of human postmortem wax-infiltrated heart specimens. Cardiovasc Pathol. 2025 Jan-Feb; 74:107690. View Abstract

  7. STK11 (LKB1) immunohistochemistry is a sensitive and specific marker for STK11 adnexal tumours. Histopathology. 2024 Nov; 85(5):769-782. View Abstract

  8. Antisense Oligonucleotide Therapy for Calmodulinopathy. Circulation. 2024 Oct 08; 150(15):1199-1210. View Abstract

  9. Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy. Res Sq. 2024 Jul 19. View Abstract

  10. Survey Data and Experience from a Pediatric Pathology Workshop in Indonesia: Understanding Practice Needs and Utility of Outreach Teachings. Fetal Pediatr Pathol. 2024 Jul-Aug; 43(4):330-340. View Abstract

  11. Pathology of explanted pediatric hearts: An 11-year study. Population characteristics and implications for outcomes. Pediatr Transplant. 2024 Jun; 28(4):e14742. View Abstract

  12. The Connection Between Anatomical Substrate and Clinical Severity in Fetal Ebstein Anomaly. Pediatr Dev Pathol. 2024 Nov-Dec; 27(6):587-591. View Abstract

  13. A modifiable valve-sparing pediatric cardiac dissection technique promotes specimen longevity and optimizes advanced image analysis postpathological examination. Pathol Int. 2024 Jul; 74(7):379-386. View Abstract

  14. Rare cardiac inflammatory pseudotumor in a toddler: Complementary roles of cardiac magnetic resonance and positron emission tomography. Cardiovasc Pathol. 2024 Jul-Aug; 71:107639. View Abstract

  15. Growth of the Neo-Aortic Root and Prognosis of Transposition of the Great Arteries. J Am Coll Cardiol. 2024 01 30; 83(4):516-527. View Abstract

  16. Outcome-Based Risk Stratification Model for the Diagnosis of Placental Maternal Vascular Malperfusion. Mod Pathol. 2024 Jan; 37(1):100370. View Abstract

  17. Death after High-Dose rAAV9 Gene Therapy in a Patient with Duchenne's Muscular Dystrophy. N Engl J Med. 2023 09 28; 389(13):1203-1210. View Abstract

  18. A novel syndrome associated with prenatal fentanyl exposure. Genet Med Open. 2023; 1(1):100834. View Abstract

  19. Gross and Histologic Placental Abnormalities Associated With Neonatal Hypoxic-Ischemic Encephalopathy. Pediatr Dev Pathol. 2024 Mar-Apr; 27(2):123-131. View Abstract

  20. Ventricular Arrhythmias in Adults With Congenital Heart Disease, Part I: JACC State-of-the-Art Review. J Am Coll Cardiol. 2023 09 12; 82(11):1108-1120. View Abstract

  21. Ventricular Arrhythmias in Adults With Congenital Heart Disease, Part II: JACC State-of-the-Art Review. J Am Coll Cardiol. 2023 09 12; 82(11):1121-1130. View Abstract

  22. Histopathology of resected tissue from repair of anomalous aortic origin of a coronary artery: Potential mechanism of coronary artery compression. JTCVS Open. 2023 Sep; 15:412-423. View Abstract

  23. Pacemaker lead insertion sites contribute to abnormalities of myocardial function and histopathology. Heart Rhythm. 2023 12; 20(12):1739-1749. View Abstract

  24. STK11 Adnexal Tumor in an Adolescent Female: Diagnostic Pitfalls of a Recently Described Entity. Pediatr Dev Pathol. 2023 Sep-Oct; 26(5):486-493. View Abstract

  25. Placental lesions attributed to shallow implantation, excess extravillous trophoblast and decidual hypoxia: Correlation with maternal vascular malperfusion and related obstetric conditions. Placenta. 2023 08; 139:61-67. View Abstract

  26. Releasing Placentas to Families: A Unified Recommendation From the Perinatal Committee of the Society for Pediatric Pathology. Arch Pathol Lab Med. 2023 05 01; 147(5):515-517. View Abstract

  27. Age-related enhanced degeneration of bioprosthetic valves due to leaflet calcification, tissue crosslinking, and structural changes. Cardiovasc Res. 2023 03 17; 119(1):302-315. View Abstract

  28. An effective rehydrating formula for reconditioning dried, irreplaceable heart specimens for teaching. Cardiovasc Pathol. 2023 Jul-Aug; 65:107528. View Abstract

  29. Gordon F. Vawter Pathologist-in-Training Award: The Outcome of Winning Abstracts in the Last 30?Years. Pediatr Dev Pathol. 2023 Mar-Apr; 26(2):172-173. View Abstract

  30. Gordon F. Vawter Pathologist-in-Training Award: The Outcome of Winning Abstracts in the Last 30?Years. Pediatr Dev Pathol. 2023 Mar-Apr; 26(2):172-173. View Abstract

  31. Neonatologist responsibility to ensure placentas are received for pathologic examination-response to comment on criteria for placental examination for obstetric and neonatal providers. Am J Obstet Gynecol. 2023 06; 228(6):762-763. View Abstract

  32. Criteria for placental examination for obstetrical and neonatal providers. Am J Obstet Gynecol. 2023 05; 228(5):497-508.e4. View Abstract

  33. 2 Cases of Spontaneous Coronary Artery Dissection in Neonates. JACC Case Rep. 2023 Jan 18; 6:101704. View Abstract

  34. Case report: Active clinical manifestation of endocardial fibroelastosis in adolescence in a patient with mitral and aortic obstruction-histologic presence of endothelial-to-mesenchymal transformation. Front Cardiovasc Med. 2022; 9:1041039. View Abstract

  35. Recurrent Second Trimester Fetal Demise Caused by Hypercoiled Umbilical Cords. Fetal Pediatr Pathol. 2023 Jun; 42(3):492-497. View Abstract

  36. Tricuspid Valve Blood Cysts Mimicking Thrombus or Vegetation on Echocardiogram in a Neonate. Pediatr Cardiol. 2023 Jan; 44(1):245-248. View Abstract

  37. Heterotopic Hepatic Tissue in the Placenta: A Case Report. Int J Surg Pathol. 2023 Aug; 31(5):634-637. View Abstract

  38. Pathologic Assessment of the Placenta: Evidence Compared With Tradition. Obstet Gynecol. 2022 08 01; 140(2):341-342. View Abstract

  39. Building Perinatal Pathology Research Capacity in Sub-Saharan Africa. Front Med (Lausanne). 2022; 9:958840. View Abstract

  40. Unrepairable Infant Mitral Valve: An Unexpected Case of Decompensated Heart Failure. Circulation. 2022 04 12; 145(15):1175-1178. View Abstract

  41. Placental Findings in Pregnancies Complicated by Maternal Cardiovascular Disease. JACC Adv. 2022 Mar; 1(1):100008. View Abstract

  42. Clinical, pathologic, and molecular analyses of superficial low-grade fibromyxoid sarcoma in two young patients: A rare and deceptive mimic of benignancy. J Cutan Pathol. 2022 Jul; 49(7):638-644. View Abstract

  43. The fetal lamb model of congenital diaphragmatic hernia shows altered cerebral perfusion using contrast enhanced ultrasound. J Pediatr Surg. 2022 Jun; 57(6):991-998. View Abstract

  44. 2q37.3 Deletion with Complex Heart Defects Suggesting Interruption of Early Ventricular Looping. Congenital Heart Disease. 2022; 17(2):141-146. View Abstract

  45. Biventricular non-compaction cardiomyopathy and tricuspid hypoplasia in a novel non-POU domain-containing octamer-binding gene variant. Cardiol Young. 2022 Aug; 32(8):1333-1337. View Abstract

  46. Perfusion-distention fixation of heart specimens: a key step in immortalizing heart specimens for wax infiltration and generating 3D imaging data sets for reconstruction and printed 3D models. Cardiovasc Pathol. 2022 May-Jun; 58:107404. View Abstract

  47. Giant Cell Myocarditis and Left Ventricular Apical Aneurysm in a Child With Severe Combined Immunodeficiency. Circ Cardiovasc Imaging. 2021 12; 14(12):1157-1158. View Abstract

  48. Giant Cell Myocarditis in Children: Elusive Giant Cells Might Not Be the Only Clue. Pediatr Dev Pathol. 2022 Mar-Apr; 25(2):197-202. View Abstract

  49. Histopathologic Changes After Pulmonary Artery Banding for Retraining of Subpulmonary Left Ventricle. Ann Thorac Surg. 2022 09; 114(3):858-865. View Abstract

  50. Heterotopic Liver Nodule Compressing a Two-Vessel Umbilical Cord: An Unusual Cause of Intrauterine Fetal Demise. Pediatr Dev Pathol. 2021 May-Jun; 24(3):241-245. View Abstract

  51. Discovery of inverted discordant p57 expression in random clusters of dysmorphic chorionic villi of third trimester placentas suggests a more common occurrence of such phenomenon than initially described. Placenta. 2021 01 15; 104:295-302. View Abstract

  52. Thrombosis of the Renal Vein and Inferior Vena Cava Associated With Placental Fetal Vascular Malperfusion in a Neonate Exposed to Methadone Maintenance Therapy In Utero. Pediatr Dev Pathol. 2021 Jan-Feb; 24(1):56-61. View Abstract

  53. TLE-1 immunoreactivity in angiomatoid fibrous histiocytoma: a potential diagnostic pitfall. Pathology. 2020 Oct; 52(6):722-725. View Abstract

  54. Chondroid and Osseous Metaplasia of the Central Fibrous Body in Adolescent Hearts with Mutations in TNNI3 and TNNT2 genes. Pediatr Dev Pathol. 2020 Nov-Dec; 23(6):453-460. View Abstract

  55. Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy. Sci Adv. 2019 09; 5(9):eaax2066. View Abstract

  56. Cystic Crypt Changes in Midgestational Human Vermiform Appendix: An Unrecognized Transient Histologic Feature. Pediatr Dev Pathol. 2019 Nov-Dec; 22(6):507-512. View Abstract

  57. Distinct Histopathological Features at Diagnosis of Very Early Onset Inflammatory Bowel Disease. J Crohns Colitis. 2019 Apr 26; 13(5):615-625. View Abstract

  58. Interdigitating Myocardial Tongues in Pediatric Cardiac Fibromas: Plausible Substrate for Ventricular Tachycardia and Cardiac Arrest. JACC Clin Electrophysiol. 2019 05; 5(5):563-575. View Abstract

  59. CD5-Positive Intravascular Large B-Cell Lymphoma in a Patient with Wilson's Disease: Case Report and Review of the Literature. Case Rep Pathol. 2018; 2018:5140586. View Abstract

  60. Pathology of valved venous homografts used as right ventricle-to-pulmonary artery conduits in congenital heart disease surgery. J Thorac Cardiovasc Surg. 2019 01; 157(1):342-350.e3. View Abstract

  61. Proton-Pump Inhibitor Treatment in Eosinophilic Esophagitis is Associated with Decreased Eosinophil Degranulation. Journal of Gastrointestinal & Digestive System. 2015; 259(5):5:259. doi:10.4172/2161-069X.1. View Abstract

  62. Ossifying fibromyxoid tumor of the breast mimicking fibroadenoma: a case report and differential diagnoses. Arch Pathol Lab Med. 2014 Aug; 138(8):1098-100. View Abstract

  63. Eosinophilic coronary monoarteritis. Arch Pathol Lab Med. 2014 Jul; 138(7):979-81. View Abstract

  64. Placental mesenchymal dysplasia with hepatic mesenchymal hamartoma: a case report and literature review. Fetal Pediatr Pathol. 2013 Dec; 32(6):448-53. View Abstract