Manuela Cernadas | Medical Services
Specialties
Programs & Services
Languages
- English
- Spanish
Manuela Cernadas | Certifications
- American Board of Internal Medicine (Adult Pulmonary Critical Care)
Manuela Cernadas | Publications
SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency. Sci Transl Med. 2024 01 24; 16(731):eadk1599. View SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency. Abstract
SARS-CoV-2 Viral Clearance and Evolution Varies by Extent of Immunodeficiency. medRxiv. 2023 Aug 07. View SARS-CoV-2 Viral Clearance and Evolution Varies by Extent of Immunodeficiency. Abstract
Diagnostic Aspirations. N Engl J Med. 2022 08 04; 387(5):452-458. View Diagnostic Aspirations. Abstract
Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut. Crit Care Explor. 2022 May; 4(5):e0699. View Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut. Abstract
The effect of elexacaftor/tezacaftor/ivacaftor (ETI) on glycemia in adults with cystic fibrosis. J Cyst Fibros. 2022 03; 21(2):258-263. View The effect of elexacaftor/tezacaftor/ivacaftor (ETI) on glycemia in adults with cystic fibrosis. Abstract
Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host. N Engl J Med. 2020 12 03; 383(23):2291-2293. View Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host. Abstract
CFTR regulates B cell activation and lymphoid follicle development. Respir Res. 2019 Jul 01; 20(1):133. View CFTR regulates B cell activation and lymphoid follicle development. Abstract
Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia. FASEB J. 2019 03; 33(3):3562-3574. View Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia. Abstract
Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma. Sci Immunol. 2018 08 03; 3(26). View Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma. Abstract
ALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2018 03 22; 3(6). View ALX receptor ligands define a biochemical endotype for severe asthma. Abstract
ALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2017 Jul 20; 2(14). View ALX receptor ligands define a biochemical endotype for severe asthma. Abstract
Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Sci Immunol. 2017 Mar 10; 2(9). View Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Abstract
Alternative Macrophage Activation Is Increased in Asthma. Am J Respir Cell Mol Biol. 2016 Oct; 55(4):467-475. View Alternative Macrophage Activation Is Increased in Asthma. Abstract
Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function. J Allergy Clin Immunol. 2016 07; 138(1):286-289.e9. View Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function. Abstract
Circadian rhythm reprogramming during lung inflammation. Nat Commun. 2014 Sep 11; 5:4753. View Circadian rhythm reprogramming during lung inflammation. Abstract
Adam8 limits the development of allergic airway inflammation in mice. J Immunol. 2013 Jun 15; 190(12):6434-49. View Adam8 limits the development of allergic airway inflammation in mice. Abstract
Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin. PLoS One. 2013; 8(5):e62910. View Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin. Abstract
Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Sci Transl Med. 2013 Feb 27; 5(174):174ra26. View Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Abstract
Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway. Angiogenesis. 2012 Sep; 15(3):457-68. View Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway. Abstract
Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):209-17. View Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion. Abstract
PTPN22.6, a dominant negative isoform of PTPN22 and potential biomarker of rheumatoid arthritis. PLoS One. 2012; 7(3):e33067. View PTPN22.6, a dominant negative isoform of PTPN22 and potential biomarker of rheumatoid arthritis. Abstract
Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis. J Immunol. 2011 Nov 15; 187(10):5255-67. View Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis. Abstract
It takes a microbiome: commensals, immune regulation, and allergy. Am J Respir Crit Care Med. 2011 Jul 15; 184(2):149-50. View It takes a microbiome: commensals, immune regulation, and allergy. Abstract
NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. J Immunol. 2011 Jun 01; 186(11):6129-35. View NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. Abstract
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol. 2011 Mar; 12(3):222-30. View Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Abstract
Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture. Arthritis Rheum. 2010 Mar; 62(3):742-52. View Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture. Abstract
Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3052-7. View Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]. Abstract
Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. J Immunol. 2010 Feb 01; 184(3):1235-41. View Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. Abstract
CD1a expression defines an interleukin-12 producing population of human dendritic cells. Clin Exp Immunol. 2009 Mar; 155(3):523-33. View CD1a expression defines an interleukin-12 producing population of human dendritic cells. Abstract
Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. Nat Immunol. 2008 Aug; 9(8):873-9. View Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. Abstract
Cigarette smoke exposure impairs dendritic cell maturation and T cell proliferation in thoracic lymph nodes of mice. J Immunol. 2008 May 15; 180(10):6623-8. View Cigarette smoke exposure impairs dendritic cell maturation and T cell proliferation in thoracic lymph nodes of mice. Abstract
PU.1 regulates cathepsin S expression in professional APCs. J Immunol. 2006 Jan 01; 176(1):275-83. View PU.1 regulates cathepsin S expression in professional APCs. Abstract
New insights into pathways for CD1-mediated antigen presentation. Curr Opin Immunol. 2004 Feb; 16(1):90-5. View New insights into pathways for CD1-mediated antigen presentation. Abstract
Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. J Immunol. 2003 Oct 15; 171(8):4149-55. View Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. Abstract
IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. J Immunol. 2003 May 01; 170(9):4457-64. View IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. Abstract
Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction. J Immunol. 2001 Mar 01; 166(5):3506-14. View Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction. Abstract
The role of alpha and beta chains in ligand recognition by beta 7 integrins. J Biol Chem. 2000 Aug 18; 275(33):25652-64. View The role of alpha and beta chains in ligand recognition by beta 7 integrins. Abstract
B7-1 (CD80) and B7-2 (CD86) have complementary roles in mediating allergic pulmonary inflammation and airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2000 Mar; 22(3):265-71. View B7-1 (CD80) and B7-2 (CD86) have complementary roles in mediating allergic pulmonary inflammation and airway hyperresponsiveness. Abstract
CD23 and allergic pulmonary inflammation: potential role as an inhibitor. Am J Respir Cell Mol Biol. 1999 Jan; 20(1):1-8. View CD23 and allergic pulmonary inflammation: potential role as an inhibitor. Abstract
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats. Circ Res. 1998 Aug 10; 83(3):279-86. View Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats. Abstract
Role of nitric oxide-related mechanisms in renal function in ageing rats. Nephrol Dial Transplant. 1998 Mar; 13(3):594-601. View Role of nitric oxide-related mechanisms in renal function in ageing rats. Abstract
Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model. J Clin Invest. 1996 Dec 15; 98(12):2693-9. View Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model. Abstract
Role of endothelium-related mechanisms in the pathophysiology of renal ischemia/reperfusion in normal rabbits. Circ Res. 1996 Nov; 79(5):1031-8. View Role of endothelium-related mechanisms in the pathophysiology of renal ischemia/reperfusion in normal rabbits. Abstract
T cell activation in a murine model of asthma. Am J Physiol. 1996 Sep; 271(3 Pt 1):L476-83. View T cell activation in a murine model of asthma. Abstract
Role of endothelin in the pathophysiology of renal ischemia-reperfusion in normal rabbits. Kidney Int. 1996 Sep; 50(3):776-82. View Role of endothelin in the pathophysiology of renal ischemia-reperfusion in normal rabbits. Abstract
Aspirin-stimulated nitric oxide production by neutrophils after acute myocardial ischemia in rabbits. Circulation. 1996 Jul 01; 94(1):83-7. View Aspirin-stimulated nitric oxide production by neutrophils after acute myocardial ischemia in rabbits. Abstract
Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart. Circulation. 1993 Sep; 88(3):1166-71. View Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart. Abstract
Renal and systemic effects of aminoacids administered separately: comparison between L-arginine and non-nitric oxide donor aminoacids. J Pharmacol Exp Ther. 1992 Dec; 263(3):1023-9. View Renal and systemic effects of aminoacids administered separately: comparison between L-arginine and non-nitric oxide donor aminoacids. Abstract