Current Environment: Production

Medical Services

Programs & Services

Languages

  • Chinese
  • English

Education

Graduate School

University of Oklahoma

2009, Norman, OK

Professional History

Dr. Da Zhang earned his PhD in Electrical and Computer Engineering from the University of Oklahoma. He received clinical training in diagnostic medical physics at Massachusetts General Hospital for five years and became a board-certified medical physicist there. Dr. Zhang spent the next six years of his career at the Beth Israel Deaconess Medical Center and was promoted to Assistant Professor of Radiology at Harvard Medical School. Dr Zhang joined Boston Children’s Hospital Radiology in 2020, his duty includes overseeing the operations of the diagnostic medical physics team in the Radiology department, as well as directing the joint diagnostic and nuclear medicine medical physics residency program. His clinical duties include medical imaging physics coverage for the radiology clinics, as well as training and consultation for physicians and clinical staff. His team is responsible for optimizing equipment performance, organizing quality control, control of radiation hazards, as well as the research and development in imaging physics and radiology informatics.

Publications

  1. Advancing quantitative PCR with color cycle multiplex amplification. Nucleic Acids Res. 2024 Sep 23; 52(17):e81. View Abstract

  2. Microsatellite Instability Detection in Cancer: A Multiplex qPCR Approach that Obviates the Need for Matching Normal Samples. Clin Chem. 2024 Jun 03; 70(6):830-840. View Abstract

  3. Two-dimensional molybdenum ditelluride waveguide-integrated near-infrared photodetector. Nanotechnology. 2024 Mar 11; 35(22). View Abstract

  4. Age-specific Dose Catalog for Diagnostic Fluoroscopy and Fluoroscopically Guided Interventional Procedures from a Pediatric Hospital. Radiology. 2024 01; 310(1):e232128. View Abstract

  5. A Call for Action on Patient Communication Efforts in Pediatric Radiology. J Am Coll Radiol. 2024 01; 21(1):44-45. View Abstract

  6. Reconsidering pregnancy screening policies for minors: patient-specific estimate of fetus and effective dose for potentially pregnant minors undergoing optimized dose CT of the pelvis. Pediatr Radiol. 2023 09; 53(10):2054-2059. View Abstract

  7. The added value of skeletal surveys in the initial evaluation of children diagnosed with Langerhans cell histiocytosis in the era of staging 18 F-FDG PET/CT: A retrospective study. Pediatr Blood Cancer. 2023 01; 70(1):e30057. View Abstract

  8. Hip Imaging in Children With Cerebral Palsy: Estimation and Intrapatient Comparison of Patient-Specific Radiation Doses of Low-Dose CT and Radiography. Invest Radiol. 2023 03 01; 58(3):190-198. View Abstract

  9. Development of a novel framework to evaluate the localization accuracy of tomosynthesis-guided breast biopsy units. Med Phys. 2021 Mar; 48(3):1299-1306. View Abstract

  10. Minimizing Radiation Dose Outliers Through Systematic Analysis, Computed Tomography Technologist Education, and Standardized System Solutions. J Comput Assist Tomogr. 2021 Jan-Feb 01; 45(1):78-83. View Abstract

  11. Long-term outcome of endovascular therapy for acute basilar artery occlusion. J Cereb Blood Flow Metab. 2021 06; 41(6):1210-1218. View Abstract

  12. Single-Energy Retrospective Metal Artifact Reduction Using Adaptive Thresholding for Metal Implants in the Abdomen and Pelvis. J Comput Assist Tomogr. 2020 May/Jun; 44(3):443-449. View Abstract

  13. Estimating patient water equivalent diameter from CT localizer images - A longitudinal and multi-institutional study of the stability of calibration parameters. Med Phys. 2020 Jun; 47(5):2139-2149. View Abstract

  14. Protein expression profiles and clinicopathologic characteristics associate with gastric cancer survival. Biol Res. 2019 Aug 09; 52(1):42. View Abstract

  15. Machine Learning for Medical Imaging. J Healthc Eng. 2019; 2019:9874591. View Abstract

  16. Comparative Dose of Contrast-Enhanced Spectral Mammography (CESM), Digital Mammography, and Digital Breast Tomosynthesis. AJR Am J Roentgenol. 2018 10; 211(4):839-846. View Abstract

  17. A new method for CT dose estimation by determining patient water equivalent diameter from localizer radiographs: Geometric transformation and calibration methods using readily available phantoms. Med Phys. 2018 Jul; 45(7):3371-3378. View Abstract

  18. Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells. Int J Mol Med. 2018 May; 41(5):2473-2484. View Abstract

  19. Point Organ Radiation Dose in Abdominal CT: Effect of Patient Off-Centering in an Experimental Human Cadaver Study. Radiat Prot Dosimetry. 2017 Aug 01; 175(4):440-449. View Abstract

  20. Metal implants on CT: comparison of iterative reconstruction algorithms for reduction of metal artifacts with single energy and spectral CT scanning in a phantom model. Abdom Radiol (NY). 2017 03; 42(3):742-748. View Abstract

  21. Serum biomarker panels for diagnosis of gastric cancer. Onco Targets Ther. 2016; 9:2455-63. View Abstract

  22. Comparison of Measured and Estimated CT Organ Doses for Modulated and Fixed Tube Current:: A Human Cadaver Study. Acad Radiol. 2016 May; 23(5):634-42. View Abstract

  23. A new technique to characterize CT scanner bow-tie filter attenuation and applications in human cadaver dosimetry simulations. Med Phys. 2015 Nov; 42(11):6274-82. View Abstract

  24. CT dose equilibration and energy absorption in polyethylene cylinders with diameters from 6 to 55 cm. Med Phys. 2015 Jun; 42(6):2882-91. View Abstract

  25. Signaling proteins and pathways affected by flavonoids in leukemia cells. Nutr Cancer. 2015; 67(2):238-49. View Abstract

  26. Data-driven CT protocol review and management—experience from a large academic hospital. J Am Coll Radiol. 2015 Mar; 12(3):267-72. View Abstract

  27. Protein profiling of preeclampsia placental tissues. PLoS One. 2014; 9(11):e112890. View Abstract

  28. Electronic cleansing in fecal-tagging dual-energy CT colonography based on material decomposition and virtual colon tagging. IEEE Trans Biomed Eng. 2015 Feb; 62(2):754-65. View Abstract

  29. Longitudinal dose distribution and energy absorption in PMMA and water cylinders undergoing CT scans. Med Phys. 2014 Oct; 41(10):101912. View Abstract

  30. Improved photoelectrical properties of n-ZnO/p-Si heterojunction by inserting an optimized thin Al2O3 buffer layer. Opt Express. 2014 Sep 08; 22(18):22184-9. View Abstract

  31. A study of the short- to long-phantom dose ratios for CT scanning without table translation. Med Phys. 2014 Sep; 41(9):091912. View Abstract

  32. In vitro dose measurements in a human cadaver with abdomen/pelvis CT scans. Med Phys. 2014 Sep; 41(9):091911. View Abstract

  33. Novel lead-free drape applied to the X-ray detector protects against scatter radiation in the angiography suite. J Vasc Interv Radiol. 2014 Aug; 25(8):1200-8. View Abstract

  34. Protein profiling of Helicobacter pylori-associated gastric cancer. Am J Pathol. 2014 May; 184(5):1343-54. View Abstract

  35. Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells. Mol Cell Biochem. 2014 Jan; 386(1-2):143-52. View Abstract

  36. A parameterization method and application in breast tomosynthesis dosimetry. Med Phys. 2013 Sep; 40(9):092105. View Abstract

  37. A method to acquire CT organ dose map using OSL dosimeters and ATOM anthropomorphic phantoms. Med Phys. 2013 Aug; 40(8):081918. View Abstract

  38. Calculations of two new dose metrics proposed by AAPM Task Group 111 using the measurements with standard CT dosimetry phantoms. Med Phys. 2013 Aug; 40(8):081914. View Abstract

  39. Workload and transmission data for the installation of a digital breast tomosynthesis system. Med Phys. 2013 Jun; 40(6):063901. View Abstract

  40. Aberrant expression of signaling proteins in essential thrombocythemia. Ann Hematol. 2013 Sep; 92(9):1229-38. View Abstract

  41. Monte Carlo assessment of CT dose equilibration in PMMA and water cylinders with diameters from 6 to 55 cm. Med Phys. 2013 Mar; 40(3):031903. View Abstract

  42. Dual-energy index value of luminal air in fecal-tagging computed tomography colonography: findings and impact on electronic cleansing. J Comput Assist Tomogr. 2013 Mar-Apr; 37(2):183-94. View Abstract

  43. Image performance evaluation of a cone beam O-arm imaging system. J Xray Sci Technol. 2013; 21(3):373-80. View Abstract

  44. Protein predictive signatures for lymph node metastasis of gastric cancer. Int J Cancer. 2013 Apr 15; 132(8):1851-9. View Abstract

  45. Virtual monochromatic reconstruction of dual-energy unenhanced head CT at 65-75 keV maximizes image quality compared with conventional polychromatic CT. Radiology. 2013 Jan; 266(1):318-25. View Abstract

  46. Equations for CT dose calculations on axial lines based on the principle of symmetry. Med Phys. 2012 Sep; 39(9):5347-52. View Abstract

  47. Transmission of broad W/Rh and W/Al (target/filter) x-ray beams operated at 25-49 kVp through common shielding materials. Med Phys. 2012 Jul; 39(7):4132-8. View Abstract

  48. X-ray spectral measurements for tungsten-anode from 20 to 49 kVp on a digital breast tomosynthesis system. Med Phys. 2012 Jun; 39(6):3493-500. View Abstract

  49. Estimation of the weighted CTDI(8) for multislice CT examinations. Med Phys. 2012 Feb; 39(2):901-5. View Abstract

  50. Cranial CT with adaptive statistical iterative reconstruction: improved image quality with concomitant radiation dose reduction. AJNR Am J Neuroradiol. 2012 Apr; 33(4):609-15. View Abstract

  51. Protein signatures for classification and prognosis of gastric cancer a signaling pathway-based approach. Am J Pathol. 2011 Oct; 179(4):1657-66. View Abstract

  52. A practical approach to estimate the weighted CT dose index over an infinite integration length. Phys Med Biol. 2011 Sep 21; 56(18):5789-803. View Abstract

  53. Automated extraction of radiation dose information from CT dose report images. AJR Am J Roentgenol. 2011 Jun; 196(6):W781-3. View Abstract

  54. Objective characterization of GE discovery CT750 HD scanner: gemstone spectral imaging mode. Med Phys. 2011 Mar; 38(3):1178-88. View Abstract

  55. Sensitivity analysis of a geometric calibration method using projection matrices for digital tomosynthesis systems. Med Phys. 2011 Jan; 38(1):202-9. View Abstract

  56. A generic geometric calibration method for tomographic imaging systems with flat-panel detectors--a detailed implementation guide. Med Phys. 2010 Jul; 37(7):3844-54. View Abstract

  57. A comparison of iterative algorithms and a mixed approach for in-line x-ray phase retrieval. Opt Commun. 2009 Aug 15; 282(16):3392-3396. View Abstract

  58. Step by step analysis toward optimal MTF algorithm using an edge test device. J Xray Sci Technol. 2009; 17(1):1-15. View Abstract

  59. A convenient alignment approach for x-ray imaging experiments based on laser positioning devices. Med Phys. 2008 Nov; 35(11):4907-10. View Abstract

  60. Preliminary feasibility study of an in-line phase contrast X-ray imaging prototype. IEEE Trans Biomed Eng. 2008 Sep; 55(9):2249-57. View Abstract

  61. DQE analysis on a dual detector phase x-ray imaging system. Phys Med Biol. 2008 Sep 21; 53(18):5165-76. View Abstract

  62. Impact of additive noise on system performance of a digital X-ray imaging system. IEEE Trans Biomed Eng. 2007 Jan; 54(1):69-73. View Abstract
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