Current Environment: Production

Publications

  1. Gazing into a Crystal Ball. N Engl J Med. 2025 May 01; 392(17):1733-1738. View Abstract

  2. Leveraging Preexisting Cardiovascular Data to Improve the Detection and Treatment of Hypertension: The NOTIFY-LVH Randomized Clinical Trial. JAMA Cardiol. 2025 Mar 31. View Abstract

  3. Traveling Companions. N Engl J Med. 2025 Feb 06; 392(6):600-606. View Abstract

  4. Botulinum neurotoxin serotype A inhibited ocular angiogenesis through modulating glial activation via SOCS3. Angiogenesis. 2024 Nov; 27(4):753-764. View Abstract

  5. SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages. Mol Ther. 2024 May 01; 32(5):1425-1444. View Abstract

  6. Photoreceptors inhibit pathological retinal angiogenesis through transcriptional regulation of Adam17 via c-Fos. Angiogenesis. 2024 Aug; 27(3):379-395. View Abstract

  7. FAM222A, Part of the BET-Regulated Basal Endothelial Transcriptome, Is a Novel Determinant of Endothelial Biology and Angiogenesis-Brief Report. Arterioscler Thromb Vasc Biol. 2024 01; 44(1):143-155. View Abstract

  8. Ocular Vascular Diseases: From Retinal Immune Privilege to Inflammation. Int J Mol Sci. 2023 Jul 28; 24(15). View Abstract

  9. Genetic deficiency and pharmacological modulation of RORa regulate laser-induced choroidal neovascularization. Aging (Albany NY). 2023 01 10; 15(1):37-52. View Abstract

  10. Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation. JCI Insight. 2022 03 22; 7(6). View Abstract

  11. Myeloid lineage contributes to pathological choroidal neovascularization formation via SOCS3. EBioMedicine. 2021 Nov; 73:103632. View Abstract

  12. Quantification of retinal blood leakage in fundus fluorescein angiography in a retinal angiogenesis model. Sci Rep. 2021 10 06; 11(1):19903. View Abstract

  13. Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier. Sci Adv. 2020 08; 6(35):eaba7457. View Abstract

  14. Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche. Sci Transl Med. 2020 08 05; 12(555). View Abstract

  15. Targeting Neuroinflammation in Neovascular Retinal Diseases. Front Pharmacol. 2020; 11:234. View Abstract

  16. Free fatty acid receptor 4 activation protects against choroidal neovascularization in mice. Angiogenesis. 2020 08; 23(3):385-394. View Abstract

  17. Targeting Neurovascular Interaction in Retinal Disorders. Int J Mol Sci. 2020 Feb 22; 21(4). View Abstract

  18. Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models. Int J Mol Sci. 2020 Feb 11; 21(4). View Abstract

  19. Dyslipidemia in retinal metabolic disorders. EMBO Mol Med. 2019 10; 11(10):e10473. View Abstract

  20. MicroRNA-145 Regulates Pathological Retinal Angiogenesis by Suppression of TMOD3. Mol Ther Nucleic Acids. 2019 Jun 07; 16:335-347. View Abstract

  21. Thrombocytopenia is associated with severe retinopathy of prematurity. JCI Insight. 2018 10 04; 3(19). View Abstract

  22. Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice. Diabetes. 2018 05; 67(5):974-985. View Abstract

  23. Photoreceptor glucose metabolism determines normal retinal vascular growth. EMBO Mol Med. 2018 01; 10(1):76-90. View Abstract

  24. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis. Nat Commun. 2017 09 19; 8(1):584. View Abstract

  25. VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis. Nat Commun. 2017 08 29; 8(1):383. View Abstract

  26. Adiponectin Mediates Dietary Omega-3 Long-Chain Polyunsaturated Fatty Acid Protection Against Choroidal Neovascularization in Mice. Invest Ophthalmol Vis Sci. 2017 08 01; 58(10):3862-3870. View Abstract

  27. Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos. J Exp Med. 2017 06 05; 214(6):1753-1767. View Abstract

  28. Sema3f Protects Against Subretinal Neovascularization In Vivo. EBioMedicine. 2017 Apr; 18:281-287. View Abstract

  29. Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis. EBioMedicine. 2016 Nov; 13:201-211. View Abstract

  30. Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nat Med. 2016 06 07; 22(6):692. View Abstract

  31. Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nat Med. 2016 Apr; 22(4):439-45. View Abstract

  32. Selective Targeting of a Novel Epsin-VEGFR2 Interaction Promotes VEGF-Mediated Angiogenesis. Circ Res. 2016 Mar 18; 118(6):957-969. View Abstract

  33. SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth. Sci Signal. 2015 Sep 22; 8(395):ra94. View Abstract

  34. Nuclear receptor RORa regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10401-6. View Abstract

  35. Optimization of an Image-Guided Laser-Induced Choroidal Neovascularization Model in Mice. PLoS One. 2015; 10(7):e0132643. View Abstract

  36. Dietary ?-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin. Am J Clin Nutr. 2015 Apr; 101(4):879-88. View Abstract

  37. A mouse model of urofacial syndrome with dysfunctional urination. Hum Mol Genet. 2015 Apr 01; 24(7):1991-9. View Abstract

  38. Endothelial TWIST1 promotes pathological ocular angiogenesis. Invest Ophthalmol Vis Sci. 2014 Nov 20; 55(12):8267-77. View Abstract

  39. The PI3K/Akt signal hyperactivates Eya1 via the SUMOylation pathway. Oncogene. 2015 May 07; 34(19):2527-37. View Abstract

  40. The canonical wnt signal restricts the glycogen synthase kinase 3/fbw7-dependent ubiquitination and degradation of eya1 phosphatase. Mol Cell Biol. 2014 Jul; 34(13):2409-17. View Abstract

  41. Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts. Dev Biol. 2014 Jan 01; 385(1):41-51. View Abstract

  42. EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1. Cancer Res. 2013 Jul 15; 73(14):4488-99. View Abstract

  43. Asymmetric requirement of surface epithelial ß-catenin during the upper and lower jaw development. Dev Dyn. 2012 Apr; 241(4):663-74. View Abstract

  44. Six1 and Eya1 are critical regulators of peri-cloacal mesenchymal progenitors during genitourinary tract development. Dev Biol. 2011 Dec 01; 360(1):186-94. View Abstract

  45. A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis. J Clin Invest. 2011 Apr; 121(4):1585-95. View Abstract

  46. A novel selenium-containing glutathione transferase zeta1-1, the activity of which surpasses the level of some native glutathione peroxidases. Int J Biochem Cell Biol. 2008; 40(10):2090-7. View Abstract

  47. Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol. 2007 Aug; 27(15):5393-402. View Abstract

  48. The molecular mechanism of protecting cells against oxidative stress by 2-selenium-bridged beta-cyclodextrin with glutathione peroxidase activity. Biochim Biophys Acta. 2005 Apr 15; 1743(3):199-204. View Abstract

  49. Selenium-containing 15-mer peptides with high glutathione peroxidase-like activity. J Biol Chem. 2004 Sep 03; 279(36):37235-40. View Abstract

  50. Protection of epidermal cells against UVB injury by the antioxidant selenium-containing single-chain Fv catalytic antibody. Arch Biochem Biophys. 2003 Apr 01; 412(1):90-4. View Abstract