Current Environment: Production

Medical Services

Specialties

Programs & Services

Languages

  • English
  • Hebrew

Education

Medical School

New York University

1996, New York, NY

Graduate School

New York University

1997, New York, NY

Internship

Pediatrics

Boston Children's Hospital

1998, Boston, MA

Residency

Pediatrics

Boston Children's Hospital

2000, Boston, MA

Fellowship

Pediatric Infectious Disease

Boston Children's Hospital

2003, Boston, MA

Certifications

  • American Board of Pediatrics (Infectious Diseases)

Media

On Answers

A new vaccine formulation could finally protect babies against RSV

Publications

  1. High affinity CD16 polymorphism associated with reduced risk of severe COVID-19. JCI Insight. 2025 May 22. View Abstract

  2. Vaccinology: Getting our modernization act together. J Exp Med. 2025 May 05; 222(5). View Abstract

  3. Safety and implementation of phase 1 randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns. J Clin Invest. 2025 Apr 03. View Abstract

  4. Correction: Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways. Clin Epigenetics. 2025 Mar 28; 17(1):53. View Abstract

  5. Network analysis reveals protein modules associated with childhood respiratory diseases. J Allergy Clin Immunol. 2025 Mar 06. View Abstract

  6. Product and trial design considerations on the path towards a vaccine to combat opioid overdose. NPJ Vaccines. 2025 Feb 19; 10(1):35. View Abstract

  7. Identification of a multi-omics factor predictive of long COVID in the IMPACC study. bioRxiv. 2025 Feb 14. View Abstract

  8. BECC-engineered live-attenuated Shigella vaccine candidates display reduced endotoxicity with robust immunogenicity in mice. Vaccine. 2025 Mar 19; 50:126779. View Abstract

  9. Pre-vaccination immune markers predict response to BNT162b2 mRNA vaccine in vulnerable groups - The CONVERS project, report from a pediatric tertiary hospital. Vaccine. 2025 Mar 07; 49:126778. View Abstract

  10. Fostering Collaboration Across Nations: Report of the 6th International Neonatal and Maternal Immunization Symposium (INMIS), Costa Rica, 2024. Pediatr Infect Dis J. 2025 Feb 01; 44(2S):S2-S8. View Abstract

  11. Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients. Nat Commun. 2025 Jan 10; 16(1):586. View Abstract

  12. Protocol for measuring anti-fentanyl antibodies in mouse serum by enzyme-linked immunosorbent assay. STAR Protoc. 2024 Dec 20; 5(4):103402. View Abstract

  13. Biomarkers of vaccine safety and efficacy in vulnerable populations: Lessons from the fourth international precision vaccines conference. Vaccine. 2025 Jan 01; 43(Pt 2):126477. View Abstract

  14. Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping. bioRxiv. 2024 Nov 25. View Abstract

  15. Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19. bioRxiv. 2024 Nov 16. View Abstract

  16. Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation. EBioMedicine. 2024 Dec; 110:105411. View Abstract

  17. Safety and implementation of a phase 1 randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns. medRxiv. 2024 Oct 17. View Abstract

  18. The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo. iScience. 2024 Nov 15; 27(11):111055. View Abstract

  19. Plasma adenosine deaminase-1 and -2 activities are lower at birth in Papua New Guinea than in The Gambia but converge over the first weeks of life. Front Immunol. 2024; 15:1425349. View Abstract

  20. Social complexity of a fentanyl vaccine to prevent opioid overdose conference proceedings: Radcliffe Institute for Advanced Study conference proceedings. Vaccine. 2025 Jan 12; 44:126324. View Abstract

  21. DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life. Nat Commun. 2024 Sep 17; 15(1):8167. View Abstract

  22. Precision adjuvants for pediatric vaccines. Sci Transl Med. 2024 09 04; 16(763):eabq7378. View Abstract

  23. Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70. Sci Transl Med. 2024 Jul 24; 16(757):eadm8451. View Abstract

  24. Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life. J Immunol Res. 2024; 2024:1117796. View Abstract

  25. Need for strategic communications and stakeholder engagement to advance acceptability of an overdose preventing vaccine targeting fentanyl. Vaccine. 2024 Oct 24; 42(24):126082. View Abstract

  26. From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation. Sci Adv. 2024 Jul 05; 10(27):eadg3747. View Abstract

  27. Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways. Clin Epigenetics. 2024 Jul 03; 16(1):85. View Abstract

  28. Network Analysis Reveals Protein Modules Associated with Childhood Respiratory Diseases. bioRxiv. 2024 Jun 17. View Abstract

  29. BECC-engineered live-attenuated Shigella vaccine candidates display reduced endotoxicity with robust immunogenicity in mice. Res Sq. 2024 Jun 11. View Abstract

  30. Heterologous SARS-CoV-2 booster vaccine for individuals with hematological malignancies after a primary SARS-CoV-2 mRNA vaccine series. Vaccine. 2024 Sep 17; 42(22):126054. View Abstract

  31. Immune profiling of age and adjuvant-specific activation of human blood mononuclear cells in vitro. Commun Biol. 2024 06 08; 7(1):709. View Abstract

  32. Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes. Sci Adv. 2024 May 24; 10(21):eadl5762. View Abstract

  33. Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality. J Clin Invest. 2024 May 01; 134(9). View Abstract

  34. Editorial: Precision vaccinology for infectious diseases. Front Immunol. 2024; 15:1400443. View Abstract

  35. Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Sci Transl Med. 2024 04 17; 16(743):eadj5154. View Abstract

  36. Respiratory Infection- and Asthma-prone, Low Vaccine Responder Children Demonstrate Distinct Mononuclear Cell DNA Methylation Pathways. Res Sq. 2024 Apr 03. View Abstract

  37. Human In vitro Modeling Identifies Adjuvant Combinations that Unlock Antigen Cross-presentation and Promote T-helper 1 Development in Newborns, Adults and Elders. J Mol Biol. 2024 02 15; 436(4):168446. View Abstract

  38. Author Correction: Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells. NPJ Vaccines. 2024 Jan 11; 9(1):13. View Abstract

  39. Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nat Commun. 2024 01 03; 15(1):216. View Abstract

  40. Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells. NPJ Vaccines. 2023 Dec 22; 8(1):189. View Abstract

  41. Modeling human immune responses to vaccination in vitro. Trends Immunol. 2024 01; 45(1):32-47. View Abstract

  42. Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. Res Sq. 2023 Dec 20. View Abstract

  43. Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants. bioRxiv. 2023 Nov 06. View Abstract

  44. Early cellular and molecular signatures correlate with severity of West Nile virus infection. iScience. 2023 Dec 15; 26(12):108387. View Abstract

  45. Corrigendum to "Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study" [eBioMedicine 83 (2022) 104208]. EBioMedicine. 2023 Dec; 98:104860. View Abstract

  46. Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen. NPJ Vaccines. 2023 Oct 26; 8(1):163. View Abstract

  47. Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance. J Allergy Clin Immunol. 2023 11; 152(5):1107-1120.e6. View Abstract

  48. Severe congenital neutropenia due to jagunal homolog 1 (JAGN1) mutation: a case report and literature review. Front Pediatr. 2023; 11:1223191. View Abstract

  49. A protocol for high-throughput screening for immunomodulatory compounds using human primary cells. STAR Protoc. 2023 09 15; 4(3):102405. View Abstract

  50. Elevated third trimester corticosteroid levels are associated with fewer offspring infections. Sci Rep. 2023 06 28; 13(1):10461. View Abstract

  51. Precision Vaccinology Approaches for the Development of Adjuvanted Vaccines Targeted to Distinct Vulnerable Populations. Pharmaceutics. 2023 Jun 19; 15(6). View Abstract

  52. Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile. Pediatr Res. 2023 11; 94(5):1667-1674. View Abstract

  53. Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients. Cell Rep Med. 2023 06 20; 4(6):101079. View Abstract

  54. Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika virus microcephaly. iScience. 2023 Jul 21; 26(7):106909. View Abstract

  55. A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics. Sci Adv. 2023 03 29; 9(13):eadf9717. View Abstract

  56. Publisher Correction: Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ Vaccines. 2023 Mar 03; 8(1):30. View Abstract

  57. Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ Vaccines. 2023 Feb 14; 8(1):18. View Abstract

  58. The mRNA vaccine BNT162b2 demonstrates impaired TH1 immunogenicity in human elders in vitro and aged mice in vivo. Res Sq. 2022 Dec 21. View Abstract

  59. Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection. Front Immunol. 2022; 13:1012824. View Abstract

  60. Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance. bioRxiv. 2022 Dec 07. View Abstract

  61. Reduced Steroid Metabolites Identify Infection-Prone Children in Two Independent Pre-Birth Cohorts. Metabolites. 2022 Nov 13; 12(11). View Abstract

  62. A single birth dose of Hepatitis B vaccine induces polyfunctional CD4+ T helper cells. Front Immunol. 2022; 13:1043375. View Abstract

  63. Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Nat Immunol. 2022 12; 23(12):1788-1798. View Abstract

  64. Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination. Nat Immunol. 2022 12; 23(12):1777-1787. View Abstract

  65. The Immune Signatures data resource, a compendium of systems vaccinology datasets. Sci Data. 2022 10 20; 9(1):635. View Abstract

  66. Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination. Sci Rep. 2022 10 18; 12(1):16860. View Abstract

  67. A Parallelization Strategy for the Time Efficient Analysis of Thousands of LC/MS Runs in High-Performance Computing Environment. J Proteome Res. 2022 11 04; 21(11):2810-2814. View Abstract

  68. Ruxolitinib for Refractory Macrophage Activation Syndrome Complicating Adult-Onset Still's Disease. Eur J Rheumatol. 2022 Oct; 9(4):217-220. View Abstract

  69. Shaping Neonatal Immunization by Tuning the Delivery of Synergistic Adjuvants via Nanocarriers. ACS Chem Biol. 2022 09 16; 17(9):2559-2571. View Abstract

  70. Immunogenicity of a Three-Dose Primary Series of mRNA COVID-19 Vaccines in Patients With Lymphoid Malignancies. Open Forum Infect Dis. 2022 Aug; 9(8):ofac417. View Abstract

  71. Advancing the Science of Vaccine Safety During the Coronavirus Disease 2019 (COVID-19) Pandemic and Beyond: Launching an International Network of Special Immunization Services. Clin Infect Dis. 2022 08 15; 75(Suppl 1):S11-S17. View Abstract

  72. Perinatally Human Immunodeficiency Virus-Infected Adolescents and Young Adults Demonstrate Distinct BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccine Immunogenicity. Clin Infect Dis. 2022 08 15; 75(Suppl 1):S51-S60. View Abstract

  73. Precision Vaccine Adjuvants for Older Adults: A Scoping Review. Clin Infect Dis. 2022 08 15; 75(Suppl 1):S72-S80. View Abstract

  74. A Precision Adjuvant Approach to Enhance Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines Optimized for Immunologically Distinct Vulnerable Populations. Clin Infect Dis. 2022 08 15; 75(Suppl 1):S30-S36. View Abstract

  75. Precision Vaccines: Lessons Learned From the Coronavirus Pandemic. Clin Infect Dis. 2022 08 15; 75(Suppl 1):S1. View Abstract

  76. Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines: Perceptions and Attitudes From the Food and Drug Administration Public Commentary. Clin Infect Dis. 2022 08 15; 75(Suppl 1):S46-S50. View Abstract

  77. Acceptability of a Fentanyl Vaccine to Prevent Opioid Overdose and Need for Personalized Decision-Making. Clin Infect Dis. 2022 08 15; 75(Suppl 1):S98-S109. View Abstract

  78. Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study. EBioMedicine. 2022 Sep; 83:104208. View Abstract

  79. mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant. Commun Biol. 2022 08 06; 5(1):790. View Abstract

  80. CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns. Nat Commun. 2022 08 02; 13(1):4234. View Abstract

  81. Adjuvant Discovery via a High Throughput Screen using Human Primary Mononuclear Cells. bioRxiv. 2022 Jul 11. View Abstract

  82. Bacille Calmette-Guérin vaccine reprograms human neonatal lipid metabolism in vivo and in vitro. Cell Rep. 2022 05 03; 39(5):110772. View Abstract

  83. Determinants of B-Cell Compartment Hyperactivation in European Adolescents Living With Perinatally Acquired HIV-1 After Over 10 Years of Suppressive Therapy. Front Immunol. 2022; 13:860418. View Abstract

  84. Waning effectiveness of SARS-CoV-2 mRNA vaccines in older adults: a rapid review. Hum Vaccin Immunother. 2022 11 30; 18(5):2045857. View Abstract

  85. An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity. Cell. 2022 02 17; 185(4):614-629.e21. View Abstract

  86. An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice. Sci Transl Med. 2022 Jan 26; 14(629):eabj5305. View Abstract

  87. BCG vaccine's off-target effects on allergic, inflammatory, and autoimmune diseases: Worth another shot? J Allergy Clin Immunol. 2022 01; 149(1):51-54. View Abstract

  88. Ontogeny of plasma cytokine and chemokine concentrations across the first week of human life. Cytokine. 2021 12; 148:155704. View Abstract

  89. SARS-CoV-2 mRNA Vaccine Attitudes as Expressed in U.S. FDA Public Commentary: Need for a Public-Private Partnership in a Learning Immunization System. Front Public Health. 2021; 9:695807. View Abstract

  90. Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation In Vitro. Front Immunol. 2021; 12:674334. View Abstract

  91. Bell's palsy and SARS-CoV-2 vaccines-an unfolding story - Authors' reply. Lancet Infect Dis. 2021 09; 21(9):1211-1212. View Abstract

  92. Plasma Adenosine Deaminase (ADA)-1 and -2 Demonstrate Robust Ontogeny Across the First Four Months of Human Life. Front Immunol. 2021; 12:578700. View Abstract

  93. Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity. bioRxiv. 2021 May 21. View Abstract

  94. Human Blood Plasma Shapes Distinct Neonatal TLR-Mediated Dendritic Cell Activation via Expression of the MicroRNA Let-7g. Immunohorizons. 2021 04 30; 5(4):246-256. View Abstract

  95. Considering Mandatory Vaccination of Children for COVID-19. Pediatrics. 2021 06; 147(6). View Abstract

  96. Bell's palsy and SARS-CoV-2 vaccines. Lancet Infect Dis. 2021 04; 21(4):450-452. View Abstract

  97. The Fifth International Neonatal and Maternal Immunization Symposium (INMIS 2019): Securing Protection for the Next Generation. mSphere. 2021 01 27; 6(1). View Abstract

  98. Vaccination of Term and Preterm Infants. Neoreviews. 2020 12; 21(12):e817-e827. View Abstract

  99. Integrative Metabolomics to Identify Molecular Signatures of Responses to Vaccines and Infections. Metabolites. 2020 Nov 30; 10(12). View Abstract

  100. Corrigendum: Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea. Front Pediatr. 2020; 8:610461. View Abstract

  101. Ensuring vaccine safety. Science. 2020 12 11; 370(6522):1274-1275. View Abstract

  102. Neonatal monocytes demonstrate impaired homeostatic extravasation into a microphysiological human vascular model. Sci Rep. 2020 10 20; 10(1):17836. View Abstract

  103. Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human Life. Front Immunol. 2020; 11:578505. View Abstract

  104. Towards Precision Vaccines: Lessons From the Second International Precision Vaccines Conference. Front Immunol. 2020; 11:590373. View Abstract

  105. A Neonatal Murine Escherichia coli Sepsis Model Demonstrates That Adjunctive Pentoxifylline Enhances the Ratio of Anti- vs. Pro-inflammatory Cytokines in Blood and Organ Tissues. Front Immunol. 2020; 11:577878. View Abstract

  106. A cloud-based bioinformatic analytic infrastructure and Data Management Core for the Expanded Program on Immunization Consortium. J Clin Transl Sci. 2020 Sep 22; 5(1):e52. View Abstract

  107. Posterior shoulder fracture-dislocation: A systematic review of the literature and current aspects of management. Chin J Traumatol. 2021 Feb; 24(1):18-24. View Abstract

  108. Electromyographic analysis of selected shoulder muscles during a series of exercises commonly used in patients with symptomatic degenerative rotator cuff tears. J Shoulder Elbow Surg. 2020 Oct; 29(10):e361-e373. View Abstract

  109. BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis. Sci Transl Med. 2020 05 06; 12(542). View Abstract

  110. Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea. Front Pediatr. 2020; 8:197. View Abstract

  111. Staphylococcus epidermidis Sensitizes Perinatal Hypoxic-Ischemic Brain Injury in Male but Not Female Mice. Front Immunol. 2020; 11:516. View Abstract

  112. Early antiretroviral therapy-treated perinatally HIV-infected seronegative children demonstrate distinct long-term persistence of HIV-specific T-cell and B-cell memory. AIDS. 2020 04 01; 34(5):669-680. View Abstract

  113. Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance. mBio. 2020 03 17; 11(2). View Abstract

  114. BCG as a Case Study for Precision Vaccine Development: Lessons From Vaccine Heterogeneity, Trained Immunity, and Immune Ontogeny. Front Microbiol. 2020; 11:332. View Abstract

  115. Vancomycin Is Protective in a Neonatal Mouse Model of Staphylococcus epidermidis-Potentiated Hypoxic-Ischemic Brain Injury. Antimicrob Agents Chemother. 2020 02 21; 64(3). View Abstract

  116. The TLR5 Agonist Flagellin Shapes Phenotypical and Functional Activation of Lung Mucosal Antigen Presenting Cells in Neonatal Mice. Front Immunol. 2020; 11:171. View Abstract

  117. Toward precision adjuvants: optimizing science and safety. Curr Opin Pediatr. 2020 02; 32(1):125-138. View Abstract

  118. Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation. Vaccine. 2020 02 24; 38(9):2229-2240. View Abstract

  119. Immunological mechanisms of inducing HIV immunity in infants. Vaccine. 2020 01 16; 38(3):411-415. View Abstract

  120. Immunometabolic approaches to prevent, detect, and treat neonatal sepsis. Pediatr Res. 2020 01; 87(2):399-405. View Abstract

  121. Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro. Pediatr Res. 2020 11; 88(5):717-725. View Abstract

  122. Vascular Endothelium in Neonatal Sepsis: Basic Mechanisms and Translational Opportunities. Front Pediatr. 2019; 7:340. View Abstract

  123. AIDS Vaccine Research Subcommittee (AVRS) Consultation: Early-Life Immunization Strategies against HIV Acquisition. mSphere. 2019 07 17; 4(4). View Abstract

  124. OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines. J Immunol Res. 2019; 2019:8732191. View Abstract

  125. Dynamic molecular changes during the first week of human life follow a robust developmental trajectory. Nat Commun. 2019 03 12; 10(1):1092. View Abstract

  126. PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function. Cancer Immunol Res. 2019 02; 7(2):257-268. View Abstract

  127. Pentoxifylline Alone or in Combination with Gentamicin or Vancomycin Inhibits Live Microbe-Induced Proinflammatory Cytokine Production in Human Cord Blood and Cord Blood Monocytes In Vitro. Antimicrob Agents Chemother. 2018 12; 62(12). View Abstract

  128. Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro. Vaccine. 2019 01 03; 37(1):80-89. View Abstract

  129. Microphysiologic Human Tissue Constructs Reproduce Autologous Age-Specific BCG and HBV Primary Immunization in vitro. Front Immunol. 2018; 9:2634. View Abstract

  130. The Fourth International Neonatal and Maternal Immunization Symposium (INMIS 2017): Toward Integrating Maternal and Infant Immunization Programs. mSphere. 2018 11 07; 3(6). View Abstract

  131. First International Precision Vaccines Conference: Multidisciplinary Approaches to Next-Generation Vaccines. mSphere. 2018 08 01; 3(4). View Abstract

  132. Immunomodulation to Prevent or Treat Neonatal Sepsis: Past, Present, and Future. Front Pediatr. 2018; 6:199. View Abstract

  133. Early Life HIV-1 Immunization: Providing a Window for Protection Before Sexual Debut. AIDS Res Hum Retroviruses. 2018 10; 34(10):823-827. View Abstract

  134. Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro. F1000Res. 2018; 7:616. View Abstract

  135. Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. PLoS One. 2018; 13(5):e0196352. View Abstract

  136. A Cost-Effective High-Throughput Plasma and Serum Proteomics Workflow Enables Mapping of the Molecular Impact of Total Pancreatectomy with Islet Autotransplantation. J Proteome Res. 2018 05 04; 17(5):1983-1992. View Abstract

  137. Neonatal Immunization: Rationale, Current State, and Future Prospects. Front Immunol. 2018; 9:532. View Abstract

  138. Hepatic Legionella pneumophila Infection in an Infant With Severe Combined Immunodeficiency. Pediatr Infect Dis J. 2018 04; 37(4):356-358. View Abstract

  139. Adjuvant Effect of Bacille Calmette-Guérin on Hepatitis B Vaccine Immunogenicity in the Preterm and Term Newborn. Front Immunol. 2018; 9:29. View Abstract

  140. Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization. Front Immunol. 2017; 8:1772. View Abstract

  141. Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation. Front Immunol. 2017; 8:1531. View Abstract

  142. Stemless Prosthesis for Total Shoulder Arthroplasty. J Am Acad Orthop Surg. 2017 Dec; 25(12):e291-e300. View Abstract

  143. The "Parachute" Technique: A Simple and Effective Single-Row Procedure to Achieve an Increased Contact Area Between the Cuff-Tendon and Its Footprint. Arthrosc Tech. 2017 Oct; 6(5):e1903-e1909. View Abstract

  144. The "Purse String" Procedure for Recurrent Anterior Glenohumeral Instability: A Simple Technique to Achieve Bankart Repair, Capsular Shift, and a Good Labral Bumper. Arthrosc Tech. 2017 Aug; 6(4):e1245-e1251. View Abstract

  145. Waning Immunity and Microbial Vaccines-Workshop of the National Institute of Allergy and Infectious Diseases. Clin Vaccine Immunol. 2017 Jul; 24(7). View Abstract

  146. Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis. PLoS One. 2017; 12(4):e0175936. View Abstract

  147. Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses. J Allergy Clin Immunol. 2017 Nov; 140(5):1339-1350. View Abstract

  148. TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth. JCI Insight. 2017 03 23; 2(6):e91020. View Abstract

  149. Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny. Immunity. 2017 03 21; 46(3):350-363. View Abstract

  150. The "Purse-string" Technique for Shoulder Stabilization, Description of the Technique, Long term Results and Literature Review. Open Orthop J. 2017; 11:183-188. View Abstract

  151. Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns. Pediatr Res. 2017 May; 81(5):806-816. View Abstract

  152. A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity. Front Immunol. 2016; 7:562. View Abstract

  153. Human newborn B cells mount an interferon-a/ß receptor-dependent humoral response to respiratory syncytial virus. J Allergy Clin Immunol. 2017 06; 139(6):1997-2000.e4. View Abstract

  154. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016 12 01; 197(11):4413-4424. View Abstract

  155. Antimicrobial Proteins and Peptides in Early Life: Ontogeny and Translational Opportunities. Front Immunol. 2016; 7:309. View Abstract

  156. "Owl" Technique for All-Arthroscopic Augmentation of a Massive or Large Rotator Cuff Tear With Extracellular Matrix Graft. Arthrosc Tech. 2016 Aug; 5(4):e717-e724. View Abstract

  157. Complications of Hip Arthroscopy: Patient Perspectives. Orthop Nurs. 2016 Jul-Aug; 35(4):208-13. View Abstract

  158. Heterologous vaccine effects. Vaccine. 2016 07 25; 34(34):3923-30. View Abstract

  159. Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells. Innate Immun. 2016 08; 22(6):433-43. View Abstract

  160. Harnessing the beneficial heterologous effects of vaccination. Nat Rev Immunol. 2016 06; 16(6):392-400. View Abstract

  161. Use of cidofovir in pediatric patients with adenovirus infection. F1000Res. 2016; 5:758. View Abstract

  162. In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. Cytokine. 2016 07; 83:99-109. View Abstract

  163. The impact of concomitant fibromyalgia on visual analogue scales of pain, fatigue and function in patients with various rheumatic disorders. Clin Exp Rheumatol. 2016 Mar-Apr; 34(2 Suppl 96):S120-4. View Abstract

  164. Circulating Human Neonatal Naïve B Cells are Deficient in CD73 Impairing Purine Salvage. Front Immunol. 2016; 7:121. View Abstract

  165. Changing oral vaccine to inactivated polio vaccine might increase mortality. Lancet. 2016 Mar 12; 387(10023):1054-1055. View Abstract

  166. Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures. Mol Cell Proteomics. 2016 06; 15(6):1877-94. View Abstract

  167. Pilot experience with opebacan/rBPI 21 in myeloablative hematopoietic cell transplantation. F1000Res. 2015; 4:1480. View Abstract

  168. Pediatric Vaccine Adjuvants: Components of the Modern Vaccinologist's Toolbox. Pediatr Infect Dis J. 2015 Dec; 34(12):1395-8. View Abstract

  169. Oral antibiotics increase blood neutrophil maturation and reduce bacteremia and necrotizing enterocolitis in the immediate postnatal period of preterm pigs. Innate Immun. 2016 Jan; 22(1):51-62. View Abstract

  170. The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes. PLoS One. 2015; 10(8):e0134640. View Abstract

  171. Systems vaccinology: a promise for the young and the poor. Philos Trans R Soc Lond B Biol Sci. 2015 Jun 19; 370(1671). View Abstract

  172. Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways. J Infect Dis. 2015 Nov 01; 212(9):1480-90. View Abstract

  173. Ready to benefit from training: heterologous effects of early life immunization. Trans R Soc Trop Med Hyg. 2015 Jan; 109(1):3-4. View Abstract

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