Erica Esrick | Medical Services
Programs & Services
Languages
- English
Erica Esrick | Education
Medical School
Pediatrics
Harvard Medical School
2004, Boston, MA
Internship
Pediatrics
Children's Memorial Hospital
2005, Chicago, IL
Residency
Pediatrics
Boston Combined Residency Program (BCRP)
2007, Boston, MA
Fellowship
Pediatric Hematology-Oncology
Boston Children's Hospital/Dana-Farber Cancer Institute
2010, Boston, MA
Erica Esrick | Certifications
- American Board of Pediatrics (Hematology-Oncology)
Erica Esrick | Media
Research

Gene therapy for sickle cell disease: The journey to a new treatment
Erica Esrick | Publications
ß-Thalassemia minor is associated with high rates of worsening anemia in pregnancy. Blood. 2025 Feb 06; 145(6):648-651. View ß-Thalassemia minor is associated with high rates of worsening anemia in pregnancy. Abstract
Clonal selection of hematopoietic stem cells after gene therapy for sickle cell disease. Nat Med. 2023 Dec; 29(12):3175-3183. View Clonal selection of hematopoietic stem cells after gene therapy for sickle cell disease. Abstract
Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling. Nat Commun. 2023 09 20; 14(1):5850. View Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling. Abstract
Bidirectional processes linking social determinants of health and pediatric sickle cell anemia management: A qualitative study. Pediatr Blood Cancer. 2023 10; 70(10):e30539. View Bidirectional processes linking social determinants of health and pediatric sickle cell anemia management: A qualitative study. Abstract
Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology Commission. Lancet Haematol. 2023 08; 10(8):e633-e686. View Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology Commission. Abstract
Secondary Neoplasms After Hematopoietic Cell Transplant for Sickle Cell Disease. J Clin Oncol. 2023 04 20; 41(12):2227-2237. View Secondary Neoplasms After Hematopoietic Cell Transplant for Sickle Cell Disease. Abstract
Metformin for treatment of cytopenias in children and young adults with Fanconi anemia. Blood Adv. 2022 06 28; 6(12):3803-3811. View Metformin for treatment of cytopenias in children and young adults with Fanconi anemia. Abstract
Investigational curative gene therapy approaches to sickle cell disease. Blood Adv. 2021 12 14; 5(23):5452. View Investigational curative gene therapy approaches to sickle cell disease. Abstract
ß-Thalassemia: evolving treatment options beyond transfusion and iron chelation. Hematology Am Soc Hematol Educ Program. 2021 12 10; 2021(1):600-606. View ß-Thalassemia: evolving treatment options beyond transfusion and iron chelation. Abstract
Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease. N Engl J Med. 2021 01 21; 384(3):205-215. View Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease. Abstract
Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy. Mol Ther Methods Clin Dev. 2020 Jun 12; 17:589-600. View Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy. Abstract
Highly efficient therapeutic gene editing of human hematopoietic stem cells. Nat Med. 2019 May; 25(5):776-783. View Highly efficient therapeutic gene editing of human hematopoietic stem cells. Abstract
Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients. Blood Adv. 2018 10 09; 2(19):2505-2512. View Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients. Abstract
Genetic therapies for sickle cell disease. Semin Hematol. 2018 04; 55(2):76-86. View Genetic therapies for sickle cell disease. Abstract
Phase 1/2 trial of vorinostat in patients with sickle cell disease who have not benefitted from hydroxyurea. Blood. 2015 Jun 04; 125(23):3668-9. View Phase 1/2 trial of vorinostat in patients with sickle cell disease who have not benefitted from hydroxyurea. Abstract
Inactivation of HDAC1 or HDAC2 induces gamma globin expression without altering cell cycle or proliferation. Am J Hematol. 2015 Jul; 90(7):624-8. View Inactivation of HDAC1 or HDAC2 induces gamma globin expression without altering cell cycle or proliferation. Abstract
Howell-Jolly–like bodies in neutrophils. Blood. 2015 Apr 23; 125(17):2729. View Howell-Jolly–like bodies in neutrophils. Abstract
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Science. 2011 Nov 18; 334(6058):993-6. View Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Abstract
Preoperative visual acuity as a prognostic indicator for laser treatment of macular edema due to branch retinal vein occlusion. Ophthalmic Surg Lasers Imaging. 2006 Nov-Dec; 37(6):462-7. View Preoperative visual acuity as a prognostic indicator for laser treatment of macular edema due to branch retinal vein occlusion. Abstract
Multiple laser treatments for macular edema attributable to branch retinal vein occlusion. Am J Ophthalmol. 2005 Apr; 139(4):653-7. View Multiple laser treatments for macular edema attributable to branch retinal vein occlusion. Abstract