Jacob Bledsoe | Medical Services
Specialties
Programs & Services
Languages
- English
Jacob Bledsoe | Education
Undergraduate School
Northwestern University
Evanston, IL
Medical School
Drexel University College of Medicine
Philadelphia, PA
Residency
Massachusetts General Hospital
Boston, MA
Fellowship
Massachusetts General Hospital
Boston, MA
Jacob Bledsoe | Certifications
- American Board of Pathology (Anatomic Clinical Pathology)
- American Board of Pathology (Hematopathology)
Jacob Bledsoe | Publications
ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance. Blood. 2025 May 07. View ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance. Abstract
Clinicopathologic Features and the Spectrum of Myelokathexis in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Syndrome. Lab Invest. 2025 Apr 14; 105(8):104174. View Clinicopathologic Features and the Spectrum of Myelokathexis in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Syndrome. Abstract
Clinical Characteristics and Treatment of Histiocytic Disorders in Children. Hematol Oncol Clin North Am. 2025 Jun; 39(3):513-529. View Clinical Characteristics and Treatment of Histiocytic Disorders in Children. Abstract
CYLD-mutated anal squamous cell carcinoma: An uncommon entity associated with cylindroma-like morphology and adverse clinical features. Hum Pathol. 2025 Mar; 157:105765. View CYLD-mutated anal squamous cell carcinoma: An uncommon entity associated with cylindroma-like morphology and adverse clinical features. Abstract
Chronic Stenosing Enteritis: A Variant of Chronic Non-specific Stenosing Ulceration (CNSU) that Is Distinct from Crohn's Disease. Dig Dis Sci. 2025 Apr; 70(4):1449-1456. View Chronic Stenosing Enteritis: A Variant of Chronic Non-specific Stenosing Ulceration (CNSU) that Is Distinct from Crohn's Disease. Abstract
Erythroblastic Sarcoma in Adults and Children: Different Pathways to the Same Destination. Mod Pathol. 2025 Feb 14; 100716. View Erythroblastic Sarcoma in Adults and Children: Different Pathways to the Same Destination. Abstract
Clinical, immunophenotypic, and genomic findings of acute myeloid leukemia with RAM immunophenotype: Comparison with other CD56-positive acute leukemias. EJHaem. 2025 Feb; 6(1):e1052. View Clinical, immunophenotypic, and genomic findings of acute myeloid leukemia with RAM immunophenotype: Comparison with other CD56-positive acute leukemias. Abstract
Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. J Allergy Clin Immunol. 2025 Apr; 155(4):1346-1356.e9. View Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. Abstract
Hematologic Cancer after Gene Therapy for Cerebral Adrenoleukodystrophy. N Engl J Med. 2024 10 10; 391(14):1287-1301. View Hematologic Cancer after Gene Therapy for Cerebral Adrenoleukodystrophy. Abstract
Primary CNS histiocytic sarcoma: Two case reports highlighting a novel MIGA2::BRAF gene fusion and genome-wide DNA methylation profiling results. J Neuropathol Exp Neurol. 2024 Oct 01; 83(10):882-886. View Primary CNS histiocytic sarcoma: Two case reports highlighting a novel MIGA2::BRAF gene fusion and genome-wide DNA methylation profiling results. Abstract
Discerning clinicopathological features of congenital neutropenia syndromes: an approach to diagnostically challenging differential diagnoses. J Clin Pathol. 2024 Aug 16; 77(9):586-604. View Discerning clinicopathological features of congenital neutropenia syndromes: an approach to diagnostically challenging differential diagnoses. Abstract
Induction of remission after donor lymphocyte infusion following allogeneic transplant in a case of pediatric primary myelofibrosis. Pediatr Blood Cancer. 2024 Oct; 71(10):e31248. View Induction of remission after donor lymphocyte infusion following allogeneic transplant in a case of pediatric primary myelofibrosis. Abstract
A novel transmembrane CXCR4 variant that expands the WHIM genotype-phenotype paradigm. Blood Adv. 2024 07 23; 8(14):3754-3759. View A novel transmembrane CXCR4 variant that expands the WHIM genotype-phenotype paradigm. Abstract
Frameshift Mutations in Leukemia-Associated Genes Correlate With Superior Outcomes in Patients Undergoing Allogeneic Stem Cell Transplant for De Novo Acute Myeloid Leukemia. J Hematol. 2024 Jun; 13(3):86-93. View Frameshift Mutations in Leukemia-Associated Genes Correlate With Superior Outcomes in Patients Undergoing Allogeneic Stem Cell Transplant for De Novo Acute Myeloid Leukemia. Abstract
Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis. Mod Pathol. 2024 Jul; 37(7):100509. View Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis. Abstract
IgG4-related lymphadenopathy. Semin Diagn Pathol. 2024 Mar; 41(2):108-115. View IgG4-related lymphadenopathy. Abstract
Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation. Clin Case Rep. 2023 Nov; 11(11):e8190. View Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation. Abstract
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma. Clin Cancer Res. 2023 11 14; 29(22):4613-4626. View Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma. Abstract
IGJ and SPATS2L immunohistochemistry sensitively and specifically identify BCR::ABL1+ and BCR::ABL1-like B-acute lymphoblastic leukaemia. Br J Haematol. 2024 01; 204(1):229-239. View IGJ and SPATS2L immunohistochemistry sensitively and specifically identify BCR::ABL1+ and BCR::ABL1-like B-acute lymphoblastic leukaemia. Abstract
Vascular leiomyoma of the thigh: Classic presentation of a rare tumor with imaging and pathology correlation. Radiol Case Rep. 2023 Nov; 18(11):4071-4075. View Vascular leiomyoma of the thigh: Classic presentation of a rare tumor with imaging and pathology correlation. Abstract
Inherited bone marrow failure syndromes and germline predisposition to myeloid neoplasia: A practical approach for the pathologist. Semin Diagn Pathol. 2023 Nov; 40(6):429-442. View Inherited bone marrow failure syndromes and germline predisposition to myeloid neoplasia: A practical approach for the pathologist. Abstract
Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders. Pediatr Blood Cancer. 2023 Jun 27; e30530. View Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders. Abstract
Immunoglobulin G4-Related Disease, Lymphadenopathy, and Lymphoma: Histopathologic Features and Diagnostic Approach. Surg Pathol Clin. 2023 Jun; 16(2):177-195. View Immunoglobulin G4-Related Disease, Lymphadenopathy, and Lymphoma: Histopathologic Features and Diagnostic Approach. Abstract
Old links revisited: Co-occurring thymoma and Castleman disease. Am J Hematol. 2023 09; 98(9):1497-1498. View Old links revisited: Co-occurring thymoma and Castleman disease. Abstract
Sporadic hyperplastic polyp associated with above-average risk of developing metachronous colorectal cancer. Am J Cancer Res. 2023; 13(2):669-677. View Sporadic hyperplastic polyp associated with above-average risk of developing metachronous colorectal cancer. Abstract
Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis. Hepatol Commun. 2022 10; 6(10):2781-2797. View Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis. Abstract
Metformin for treatment of cytopenias in children and young adults with Fanconi anemia. Blood Adv. 2022 06 28; 6(12):3803-3811. View Metformin for treatment of cytopenias in children and young adults with Fanconi anemia. Abstract
Reply to "Limitations of multivariate survival analysis". Mod Pathol. 2022 07; 35(7):994-995. View Reply to "Limitations of multivariate survival analysis". Abstract
Impact of pretransplant mutation status on survival after allogeneic stem cell transplant for acute myeloid leukemia. EJHaem. 2021 Aug; 2(3):514-519. View Impact of pretransplant mutation status on survival after allogeneic stem cell transplant for acute myeloid leukemia. Abstract
Rapid and Deep Remission Induced by Blinatumomab for CD19-Positive Chronic Myeloid Leukemia in Lymphoid Blast Phase. JCO Precis Oncol. 2021 07; 5. View Rapid and Deep Remission Induced by Blinatumomab for CD19-Positive Chronic Myeloid Leukemia in Lymphoid Blast Phase. Abstract
Polyclonal PAX8 expression in carcinomas of the biliary tract - Frequent non-specific staining represents a potential diagnostic pitfall. Ann Diagn Pathol. 2021 Aug; 53:151762. View Polyclonal PAX8 expression in carcinomas of the biliary tract - Frequent non-specific staining represents a potential diagnostic pitfall. Abstract
CD56 expression in basaloid anal squamous cell carcinoma - A potential diagnostic pitfall. Ann Diagn Pathol. 2021 Aug; 53:151758. View CD56 expression in basaloid anal squamous cell carcinoma - A potential diagnostic pitfall. Abstract
IgG4-related Lymphadenopathy: A Comparative Study of 41 Cases Reveals Distinctive Histopathologic Features. Am J Surg Pathol. 2021 02 01; 45(2):178-192. View IgG4-related Lymphadenopathy: A Comparative Study of 41 Cases Reveals Distinctive Histopathologic Features. Abstract
Molecular and immunophenotypic characterization of anal squamous cell carcinoma reveals distinct clinicopathologic groups associated with HPV and TP53 mutation status. Mod Pathol. 2021 05; 34(5):1017-1030. View Molecular and immunophenotypic characterization of anal squamous cell carcinoma reveals distinct clinicopathologic groups associated with HPV and TP53 mutation status. Abstract
LGR5 in Barrett's Esophagus and its Utility in Predicting Patients at Increased Risk of Advanced Neoplasia. Clin Transl Gastroenterol. 2020 12 22; 12(1):e00272. View LGR5 in Barrett's Esophagus and its Utility in Predicting Patients at Increased Risk of Advanced Neoplasia. Abstract
A deep learning diagnostic platform for diffuse large B-cell lymphoma with high accuracy across multiple hospitals. Nat Commun. 2020 11 26; 11(1):6004. View A deep learning diagnostic platform for diffuse large B-cell lymphoma with high accuracy across multiple hospitals. Abstract
Clonal IgH gene rearrangements identify Richter's transformation to diffuse large B cell lymphoma. Ann Hematol. 2021 Dec; 100(12):3075-3077. View Clonal IgH gene rearrangements identify Richter's transformation to diffuse large B cell lymphoma. Abstract
Outcomes After Stereotactic Body Radiation Therapy as a Bridging Modality to Liver Transplantation for Hepatocellular Carcinoma. Adv Radiat Oncol. 2021 Jan-Feb; 6(1):100559. View Outcomes After Stereotactic Body Radiation Therapy as a Bridging Modality to Liver Transplantation for Hepatocellular Carcinoma. Abstract
CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features. Mod Pathol. 2021 02; 34(2):358-370. View CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features. Abstract
Extramedullary Acute Myeloid Leukemia of the Renal Pelvis: Insights into a Visceral Niche. Acta Haematol. 2021; 144(3):297-301. View Extramedullary Acute Myeloid Leukemia of the Renal Pelvis: Insights into a Visceral Niche. Abstract
Resolution of Severe Graft Steatosis Before Living-Donor Liver Transplant After 86 Pounds of Weight Loss. Exp Clin Transplant. 2022 09; 20(9):874-877. View Resolution of Severe Graft Steatosis Before Living-Donor Liver Transplant After 86 Pounds of Weight Loss. Abstract
Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma in Patients With Child-Pugh B or C Cirrhosis. Adv Radiat Oncol. 2020 Sep-Oct; 5(5):889-896. View Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma in Patients With Child-Pugh B or C Cirrhosis. Abstract
Frozen section diagnosis of gastrointestinal poorly cohesive and signet-ring cell adenocarcinoma: useful morphologic features to avoid misdiagnosis. Virchows Arch. 2020 Oct; 477(4):497-506. View Frozen section diagnosis of gastrointestinal poorly cohesive and signet-ring cell adenocarcinoma: useful morphologic features to avoid misdiagnosis. Abstract
Metastatic Signet Ring Cell Carcinoma of the Ampulla of Vater with an Unusually Prolonged Survival. J Gastrointest Cancer. 2020 Mar; 51(1):354-358. View Metastatic Signet Ring Cell Carcinoma of the Ampulla of Vater with an Unusually Prolonged Survival. Abstract
The Use of Smartphone for Liver Graft Biopsy Assessment at the Time of Procurement. Transplantation. 2018 11; 102(11):e459-e460. View The Use of Smartphone for Liver Graft Biopsy Assessment at the Time of Procurement. Abstract
IgG4-related disease: review of the histopathologic features, differential diagnosis, and therapeutic approach. APMIS. 2018 Jun; 126(6):459-476. View IgG4-related disease: review of the histopathologic features, differential diagnosis, and therapeutic approach. Abstract
Lymphomas in IgG4-related disease: clinicopathologic features in a Western population. Virchows Arch. 2018 May; 472(5):839-852. View Lymphomas in IgG4-related disease: clinicopathologic features in a Western population. Abstract
Atypical IgG4+ Plasmacytic Proliferations and Lymphomas: Characterization of 11 Cases. Am J Clin Pathol. 2017 Sep 01; 148(3):215-235. View Atypical IgG4+ Plasmacytic Proliferations and Lymphomas: Characterization of 11 Cases. Abstract
Diverse repetitive element RNA expression defines epigenetic and immunologic features of colon cancer. JCI Insight. 2017 02 09; 2(3):e91078. View Diverse repetitive element RNA expression defines epigenetic and immunologic features of colon cancer. Abstract
The immunophenotypic spectrum of primary mediastinal large B-cell lymphoma reveals prognostic biomarkers associated with outcome. Am J Hematol. 2016 10; 91(10):E436-41. View The immunophenotypic spectrum of primary mediastinal large B-cell lymphoma reveals prognostic biomarkers associated with outcome. Abstract
PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes. Mod Pathol. 2016 09; 29(9):1104-12. View PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes. Abstract
Amyloidosis of the liver on shear wave elastography: case report and review of literature. Abdom Imaging. 2015 Oct; 40(8):3078-83. View Amyloidosis of the liver on shear wave elastography: case report and review of literature. Abstract
Difficult Diagnostic Problems in Pancreatobiliary Neoplasia. Arch Pathol Lab Med. 2015 Jul; 139(7):848-57. View Difficult Diagnostic Problems in Pancreatobiliary Neoplasia. Abstract
Authors’ reply. Int J Chron Obstruct Pulmon Dis. 2015; 10:871. View Authors’ reply. Abstract
Smoking-associated fibrosis and pulmonary asbestosis. Int J Chron Obstruct Pulmon Dis. 2015; 10:31-7. View Smoking-associated fibrosis and pulmonary asbestosis. Abstract
BRAF V600E immunohistochemistry is reliable in primary and metastatic colorectal carcinoma regardless of treatment status and shows high intratumoral homogeneity. Am J Surg Pathol. 2014 Oct; 38(10):1418-28. View BRAF V600E immunohistochemistry is reliable in primary and metastatic colorectal carcinoma regardless of treatment status and shows high intratumoral homogeneity. Abstract
Fine needle aspiration biopsy of an unusual follicular adenoma with sebaceous-like features. Endocr Pathol. 2012 Sep; 23(3):177-80. View Fine needle aspiration biopsy of an unusual follicular adenoma with sebaceous-like features. Abstract