MEDIA
Caregiver Profile
Caregiver Profile
Meet Dr. Aditya "AK" Kaza
MEDICAL SERVICES
EDUCATION
Undergraduate Degree
- Boston University , 1996 , Boston , MA
Medical School
- Boston University School of Medicine , 1996 , Boston , MA
Internship
- Ochsner Clinic Foundation , 1997 , New Orleans , LA
Residency
- Ochsner Clinic Foundation , 1999, 2003 , New Orleans , LA
Fellowship
Research
- University of Virginia , 2001 , Charlottesville , VA
Fellowship
Cardiothoracic Surgery
- University of Colorado Health Sciences Center , 2006 , Denver , CO
Fellowship
Pediatric Cardiac Surgery
- Denver Children's Hospital , 2007 , Denver , CO
Fellowship
Pediatric Cardiac Surgery; Chief Resident Year
- Boston Children's Hospital , 2008 , Boston , MA
Graduate Degree
- Massachusetts Institute of Technology , 2018 , Cambridge , MA
Philosophy of Care
I am a congenital cardiac surgeon who cares for neonates, infants, children and adults born with congenital heart disease. I perform a wide spectrum of surgeries for congenital heart defects. My goal is to provide innovative and “cutting edge” cardiac surgical care in an ethical, compassionate, and family-centric fashion.
I am actively involved in all aspects of congenital heart surgery with special emphasis on complete neonatal repairs and cardiac critical care. In addition, I have an active research program with two main goals. The first is to understand the role of prematurity in myocardial recovery after heart surgery. The second focus is working with a multidisciplinary team to develop new and innovative devices to improve care of infants and children with heart disease. I am currently funded by the NIH, B-BIC and the Boston Children’s Hospital Innovestment Grant.
I have a special interest in the education and training of residents and fellows. I have had the privilege of being part of the Thoracic Surgery resident workforce at the Society of Thoracic Surgeons. In this capacity, I helped with administering the scholarship program of the STS for residents and medical students. As a congenital cardiac surgeon, I interact and teach house-staff from various sub-specialties such as congenital cardiac surgery, thoracic surgery, pediatric cardiology, pediatrics, and pediatric critical care.
PROFESSIONAL HISTORY
I matriculated from medical school at Boston University, followed by a five year surgical residency at the Ochsner Clinic. During my surgical residency, I took two years off to spend in the thoracic and cardiovascular surgery research laboratory at the University of Virginia. Subsequently, I did my cardiothoracic surgery fellowship at the University of Colorado. I stayed an extra year in Denver to do a fellowship in pediatric cardiac surgery. I then came to Boston for my twelfth and final year of post-graduate training to serve as the chief resident in congenital cardiac surgery. I took my first job in pediatric cardiac surgery at the University of Utah and based at Primary Children’s Hospital. I was in practice there for five years when I was recruited to Boston Children’s Hospital. I have been at Boston Children’s Hospital since 2013 and am involved in all aspects of congenital heart surgery.
CERTIFICATIONS
- American Board of Thoracic Surgery
- American Board of Thoracic Surgery, Congenital Heart Surgery
PUBLICATIONS
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- Hyperlactataemia as a predictor of adverse outcomes post-cardiac surgery in neonates with congenital heart disease. Cardiol Young. 2021 Feb 09; 1-6. View abstract
- Commentary: Evolving Strategies for Pulmonary Artery Rehabilitation in Single Ventricle Physiology. Semin Thorac Cardiovasc Surg. 2020 Nov 07. View abstract
- Technical Performance Score: A Predictor of Outcomes After the Norwood Procedure. Ann Thorac Surg. 2020 Sep 25. View abstract
- Commentary: An opportunity to better characterize coronary ostial stenosis in patients with Williams syndrome and other elastin arteriopathies. J Thorac Cardiovasc Surg. 2020 Sep 10. View abstract
- Response to comments on preclinical evaluation of a pediatric airway stent for tracheobronchomalacia. J Thorac Cardiovasc Surg. 2020 Aug 27. View abstract
- Intraoperative localization of cardiac conduction tissue regions using real-time fibre-optic confocal microscopy: first in human trial. Eur J Cardiothorac Surg. 2020 08 01; 58(2):261-268. View abstract
- Toward detection of conduction tissue during cardiac surgery: Light at the end of the tunnel? Heart Rhythm. 2020 Dec; 17(12):2200-2207. View abstract
- Early Infant Symptomatic Patients With Tetralogy of Fallot With Absent Pulmonary Valve: Pulmonary Artery Management and Airway Stabilization. Ann Thorac Surg. 2020 11; 110(5):1644-1650. View abstract
- Stress ulcer prophylaxis versus placebo-a blinded randomized control trial to evaluate the safety of two strategies in critically ill infants with congenital heart disease (SUPPRESS-CHD). Trials. 2020 Jun 29; 21(1):590. View abstract
- Predictors of Increased Lactate in Neonatal Cardiac Surgery: The Impact of Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 2021 Jan; 35(1):148-153. View abstract
- Localization of the sinoatrial and atrioventricular nodal region in neonatal and juvenile ovine hearts. PLoS One. 2020; 15(5):e0232618. View abstract
- Preclinical evaluation of a pediatric airway stent for tracheobronchomalacia. J Thorac Cardiovasc Surg. 2020 Mar 15. View abstract
- Commentary: Truncal root remodeling: A useful technique that can be translated to other lesions? J Thorac Cardiovasc Surg. 2021 02; 161(2):376-377. View abstract
- Echocardiographic Diagnosis of Anomalous Single Coronary Artery from the Pulmonary Artery: Use of Bubble Contrast Echocardiography. Pediatr Cardiol. 2020 Jan; 41(1):215-216. View abstract
- Fontan with lateral tunnel is associated with improved survival compared with extracardiac conduit. J Thorac Cardiovasc Surg. 2020 04; 159(4):1480-1491.e2. View abstract
- Acute coronary artery obstruction following surgical repair of congenital heart disease. J Thorac Cardiovasc Surg. 2020 05; 159(5):1957-1965.e1. View abstract
- Renal replacement therapy in the pediatric cardiac intensive care unit. J Thorac Cardiovasc Surg. 2019 11; 158(5):1446-1455. View abstract
- Long-term Surgical Prognosis of Primary Supravalvular Aortic Stenosis Repair. Ann Thorac Surg. 2019 10; 108(4):1202-1209. View abstract
- Pediatric Airway Stent Designed to Facilitate Mucus Transport and Atraumatic Removal. IEEE Trans Biomed Eng. 2020 01; 67(1):177-184. View abstract
- An Imaging Protocol to Discriminate Specialized Conduction Tissue During Congenital Heart Surgery. Semin Thorac Cardiovasc Surg. 2019; 31(3):537-546. View abstract
- Impact of a Composite Valved RV-PA Graft After Stage 1 Palliation. Ann Thorac Surg. 2018 11; 106(5):1452-1459. View abstract
- Targeted Increase in Pulmonary Blood Flow in a Bidirectional Glenn Circulation. Semin Thorac Cardiovasc Surg. 2018; 30(2):182-188. View abstract
- What is the ideal conduit or technique for reconstruction of the right ventricular outflow tract? J Thorac Cardiovasc Surg. 2018 05; 155(5):2080-2081. View abstract
- Right ventricular outflow tract reintervention after primary tetralogy of Fallot repair in neonates and young infants. J Thorac Cardiovasc Surg. 2018 02; 155(2):726-734. View abstract
- Filling a significant gap in the cardiac ICU: implementation of individualised developmental care. Cardiol Young. 2017 Nov; 27(9):1797-1806. View abstract
- A Method to Account for Variation in Congenital Heart Surgery Length of Stay. Pediatr Crit Care Med. 2017 Jun; 18(6):550-560. View abstract
- Non-invasive Assessment of Cerebral Blood Flow and Oxygen Metabolism in Neonates during Hypothermic Cardiopulmonary Bypass: Feasibility and Clinical Implications. Sci Rep. 2017 03 09; 7:44117. View abstract
- Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion. J Thorac Cardiovasc Surg. 2017 04; 153(4):934-943. View abstract
- Phosphodiesterase Inhibitor-Based Vasodilation Improves Oxygen Delivery and Clinical Outcomes Following Stage 1 Palliation. J Am Heart Assoc. 2016 11 02; 5(11). View abstract
- Association of Extracorporeal Membrane Oxygenation Support Adequacy and Residual Lesions With Outcomes in Neonates Supported After Cardiac Surgery. Pediatr Crit Care Med. 2016 11; 17(11):1045-1054. View abstract
- The need for personalized resuscitation guidelines in children with congenital heart disease. J Thorac Cardiovasc Surg. 2017 02; 153(2):459. View abstract
- Are attempts at regulating flow through systemic-to-pulmonary arterial shunts still valid? J Thorac Cardiovasc Surg. 2016 11; 152(5):1353-1354. View abstract
- Left Ventricular Outflow Tract Obstruction: Coarctation of the Aorta, Interrupted Aortic Arch, and Borderline Left Ventricle. Pediatr Crit Care Med. 2016 08; 17(8 Suppl 1):S315-7. View abstract
- Techniques to aid pulmonary valve preservation during repair of tetralogy of Fallot. J Thorac Cardiovasc Surg. 2016 Jun; 151(6):1759. View abstract
- Sensitivity and Specificity of Cardiac Tissue Discrimination Using Fiber-Optics Confocal Microscopy. PLoS One. 2016; 11(1):e0147667. View abstract
- Are Bioprosthetic Valves Appropriate for Aortic Valve Replacement in Young Patients? Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2016; 19(1):63-7. View abstract
- Heart transplantation in patients who have congenital heart disease and single-lung physiology. J Thorac Cardiovasc Surg. 2015 Dec; 150(6):1473. View abstract
- Intravenous GPIIb/IIIa Inhibitor for Secondary Prevention of Shunt Thrombosis in a Pediatric Patient. Ann Thorac Surg. 2015 Jun; 99(6):e151-3. View abstract
- Surgical approaches to critical aortic stenosis with unicommissural valve in neonates. Expert Rev Cardiovasc Ther. 2014 Dec; 12(12):1401-5. View abstract
- Local delivery of fluorescent dye for fiber-optics confocal microscopy of the living heart. Front Physiol. 2014; 5:367. View abstract
- Fontan modification with a Y-graft. J Thorac Cardiovasc Surg. 2015 Jan; 149(1):246. View abstract
- Neonatal flail tricuspid valve: diagnosis and management. Ann Thorac Surg. 2014 Sep; 98(3):1098-101. View abstract
- Pulmonary vascular remodelling after heart transplantation in patients with cavopulmonary connection. Eur J Cardiothorac Surg. 2015 Mar; 47(3):505-10; discussion 510. View abstract
- Heart failure due to "disappearing" aortic valve in hypoplastic left heart syndrome. World J Pediatr Congenit Heart Surg. 2014 Apr; 5(2):334-7. View abstract
- Survival based on patient selection for heart transplant in adults with congenital heart disease: a multi-institutional study. Int J Cardiol. 2014; 172(1):e89-90. View abstract
- Surgical approaches for CHD: and update on success and challenges. Curr Opin Pediatr. 2013 Oct; 25(5):591-6. View abstract
- Identification of nodal tissue in the living heart using rapid scanning fiber-optics confocal microscopy and extracellular fluorophores. Circ Cardiovasc Imaging. 2013 Sep; 6(5):739-46. View abstract
- Cardiac performance and quality of life in patients who have undergone the Fontan procedure with and without prior superior cavopulmonary connection. Cardiol Young. 2013 Jun; 23(3):335-43. View abstract
- Effect of ventricular size and function on exercise performance and the electrocardiogram in repaired tetralogy of Fallot with pure pulmonary regurgitation. Ann Pediatr Cardiol. 2012 Jul; 5(2):151-5. View abstract
- Variation in perioperative care across centers for infants undergoing the Norwood procedure. J Thorac Cardiovasc Surg. 2012 Oct; 144(4):915-21. View abstract
- Biopsy-diagnosed antibody-mediated rejection based on the proposed International Society for Heart and Lung Transplantation working formulation is associated with adverse cardiovascular outcomes after pediatric heart transplant. J Heart Lung Transplant. 2012 Jul; 31(7):686-93. View abstract
- Early survival after heart transplant in young infants is lowest after failed single-ventricle palliation: a multi-institutional study. J Heart Lung Transplant. 2012 May; 31(5):509-16. View abstract
- Changes in left atrioventricular valve geometry after surgical repair of complete atrioventricular canal. J Thorac Cardiovasc Surg. 2012 May; 143(5):1117-24. View abstract
- Surgical interventions for atrioventricular septal defect subtypes: the pediatric heart network experience. Ann Thorac Surg. 2011 Oct; 92(4):1468-75; discussion 1475. View abstract
- Postoperative dissecting ventricular septal hematoma: recognition and treatment. ISRN Pediatr. 2011; 2011:534940. View abstract
- Would access to device therapies improve transplant outcomes for adults with congenital heart disease? Analysis of the United Network for Organ Sharing (UNOS). J Heart Lung Transplant. 2011 Apr; 30(4):395-401. View abstract
- Durability of truncal valve repair. Ann Thorac Surg. 2010 Oct; 90(4):1307-12; discussion 1312. View abstract
- Clinical performance of decellularized cryopreserved valved allografts compared with standard allografts in the right ventricular outflow tract. Ann Thorac Surg. 2010 Oct; 90(4):1301-5; discussion 1306. View abstract
- Simple versus complex truncus arteriosus: neutralization of risk but with increased resource utilization. World J Pediatr Congenit Heart Surg. 2010 Oct; 1(3):285-91. View abstract
- Anomalous origin of the left coronary artery from the pulmonary artery in Alagille syndrome. Congenit Heart Dis. 2010 Sep-Oct; 5(5):462-4. View abstract
- Experience with the Levitronix CentriMag in the pediatric population as a bridge to decision and recovery. Artif Organs. 2009 Nov; 33(11):1002-4. View abstract
- Management of deep wound complications with vacuum-assisted therapy after Berlin Heart EXCOR ventricular assist device placement in the pediatric population. Artif Organs. 2009 Nov; 33(11):922-5. View abstract
- Effect of ABO-incompatible listing on infant heart transplant waitlist outcomes: analysis of the United Network for Organ Sharing (UNOS) database. J Heart Lung Transplant. 2009 Dec; 28(12):1254-60. View abstract
- Evaluating failing Fontans for heart transplantation: predictors of death. Ann Thorac Surg. 2009 Aug; 88(2):558-63; discussion 563-4. View abstract
- Long-term results of right ventricular outflow tract reconstruction in neonatal cardiac surgery: options and outcomes. J Thorac Cardiovasc Surg. 2009 Oct; 138(4):911-6. View abstract
- Analysis of the US Food and Drug Administration Manufacturer and User Facility Device Experience database for adverse events involving Amplatzer septal occluder devices and comparison with the Society of Thoracic Surgery congenital cardiac surgery database. J Thorac Cardiovasc Surg. 2009 Jun; 137(6):1334-41. View abstract
- Stentless porcine valves in the right ventricular outflow tract: improved durability? Eur J Cardiothorac Surg. 2009 Apr; 35(4):600-4; discussion 604-5. View abstract
- True aneurysmal dilatation of a contegra conduit after right ventricular outflow tract reconstruction: a novel mechanism of conduit failure. Ann Thorac Surg. 2008 Dec; 86(6):1976-7. View abstract
- Partial left pulmonary artery sling associated with multiple ventricular septal defects: a rare congenital anomaly. J Thorac Cardiovasc Surg. 2008 Oct; 136(4):1085-7. View abstract
- Preoperative pulmonary evaluation of the thoracic surgical patient. Thorac Surg Clin. 2005 May; 15(2):297-304. View abstract
- Pyrrolidine dithiocarbamate reduces lung reperfusion injury. J Surg Res. 2003 Jun 01; 112(1):12-8. View abstract
- Elimination of fat microemboli during cardiopulmonary bypass. Ann Thorac Surg. 2003 Feb; 75(2):555-9; discussion 559. View abstract
- Preoperative shock determines outcome for acute type A aortic dissection. Ann Thorac Surg. 2003 Feb; 75(2):520-4. View abstract
- Adenosine A2A receptor activation decreases reperfusion injury associated with high-flow reperfusion. J Thorac Cardiovasc Surg. 2002 Nov; 124(5):973-8. View abstract
- Keratinocyte growth factor enhances post-pneumonectomy lung growth by alveolar proliferation. Circulation. 2002 Sep 24; 106(12 Suppl 1):I120-4. View abstract
- Adenosine A2A agonist reduces paralysis after spinal cord ischemia: correlation with A2A receptor expression on motor neurons. Ann Thorac Surg. 2002 Sep; 74(3):846-9; discussion 849-50. View abstract
- Controlled perfusion decreases reperfusion injury after high-flow reperfusion. J Heart Lung Transplant. 2002 Jun; 21(6):687-91. View abstract
- Ventricular reconstruction results in improved left ventricular function and amelioration of mitral insufficiency. Ann Surg. 2002 Jun; 235(6):828-32. View abstract
- Inhibition of compensatory lung growth in endothelial nitric oxide synthase-deficient mice. . 2002 Jun; 282(6):L1272-8. View abstract
- Repair of an anomalous left coronary artery. Cardiovasc Surg. 2002 Jun; 10(3):276-8. View abstract
- Adenosine A2A analogue ATL-146e reduces systemic tumor necrosing factor-alpha and spinal cord capillary platelet-endothelial cell adhesion molecule-1 expression after spinal cord ischemia. J Vasc Surg. 2002 May; 35(5):994-8. View abstract
- Ischemia-reperfusion injury after lung transplantation increases risk of late bronchiolitis obliterans syndrome. Ann Thorac Surg. 2002 Apr; 73(4):1041-7; discussion 1047-8. View abstract
- Coronary risk stratification in patients with end-stage lung disease. J Heart Lung Transplant. 2002 Mar; 21(3):334-9. View abstract
- Contrasting natures of lung growth after transplantation and lobectomy. J Thorac Cardiovasc Surg. 2002 Feb; 123(2):288-94. View abstract
- Cardioscope-assisted excision of a left ventricular tumor--a case report. Heart Surg Forum. 2002; 5(1):75-6. View abstract
- Donor lung salvage after neurogenic pulmonary edema with the use of post-transplant extracorporeal membrane oxygenation. J Thorac Cardiovasc Surg. 2001 Dec; 122(6):1257-8. View abstract
- Management of innominate artery injury in the setting of bovine arch anomaly. Ann Thorac Surg. 2001 Dec; 72(6):2134-6. View abstract
- Influence of graft ischemic time on outcomes following lung transplantation. J Heart Lung Transplant. 2001 Dec; 20(12):1291-6. View abstract
- A cost comparison of heart transplantation versus alternative operations for cardiomyopathy. Ann Thorac Surg. 2001 Oct; 72(4):1298-305. View abstract
- Systemic adenosine A2A agonist ameliorates ischemic reperfusion injury in the rabbit spinal cord. Ann Thorac Surg. 2001 Oct; 72(4):1245-50. View abstract
- As originally published in 1994: Ambulatory intraaortic balloon counterpulsation. Updated in 2001. Ann Thorac Surg. 2001 Sep; 72(3):975. View abstract
- An adenosine A2A agonist, ATL-146e, reduces paralysis and apoptosis during rabbit spinal cord reperfusion. J Vasc Surg. 2001 Sep; 34(3):482-8. View abstract
- Adenosine analogue reduces spinal cord reperfusion injury in a time-dependent fashion. Surgery. 2001 Aug; 130(2):230-5. View abstract
- A technique for adequate coverage of the proximal suture line during abdominal aortic aneurysm repair. J Vasc Surg. 2001 Aug; 34(2):367-8. View abstract
- Epidermal growth factor receptor up-regulation is associated with lung growth after lobectomy. Ann Thorac Surg. 2001 Aug; 72(2):380-5. View abstract
- Carotid arteriography impacts carotid stenosis management. Vasc Surg. 2001 Jul-Aug; 35(4):251-6; discussion 257. View abstract
- Cardiac reoperation in the intensive care unit. Ann Thorac Surg. 2001 Jun; 71(6):1888-92; discussion 1892-3. View abstract
- Early intervention after severe oxygenation index elevation improves survival following lung transplantation. J Heart Lung Transplant. 2001 Jun; 20(6):631-6. View abstract
- Lung transplant reperfusion injury involves pulmonary macrophages and circulating leukocytes in a biphasic response. J Thorac Cardiovasc Surg. 2001 Jun; 121(6):1069-75. View abstract
- Retinoic acid enhances lung growth after pneumonectomy. Ann Thorac Surg. 2001 May; 71(5):1645-50. View abstract
- Aerosolized prostacyclin (epoprostenol) as an alternative to inhaled nitric oxide for patients with reperfusion injury after lung transplantation. J Thorac Cardiovasc Surg. 2001 May; 121(5):981-2. View abstract
- Pulmonary macrophages are involved in reperfusion injury after lung transplantation. Ann Thorac Surg. 2001 Apr; 71(4):1134-8; discussion 1138-9. View abstract
- Influence of graft ischemia time on outcomes following lung transplantation. J Heart Lung Transplant. 2001 Feb; 20(2):206-207. View abstract
- Controlled perfusion decreases lung transplant reperfusion injury in the setting of high flow reperfusion. J Heart Lung Transplant. 2001 Feb; 20(2):183. View abstract
- A technique for the treatment of sternal infections using the Vacuum Assisted Closure device. Heart Surg Forum. 2001; 4(3):211-5. View abstract
- When to discontinue extracorporeal membrane oxygenation for postcardiotomy support. Ann Thorac Surg. 2001 Jan; 71(1):210-4. View abstract
- Xenotransplantation update. Heart Surg Forum. 2001; 4(3):261-5. View abstract
- A long-term ventricular assist device utilizing a magnetic bearing system and implantable physiologic controller. Heart Surg Forum. 2001; 4(1):11-2. View abstract
- Epidermal growth factor augments postpneumonectomy lung growth. J Thorac Cardiovasc Surg. 2000 Nov; 120(5):916-21. View abstract