Samuel Nurko

Samuel Nurko, MD, MPH

Director, Center for Motility and Functional Gastrointestinal Disorders; Director, Functional Abdominal Pain Program

Professor of Pediatrics, Harvard Medical School

    Contact: 617-355-6055
  • Fax: 617-730-0495

Medical Services

Specialties

  • Irritable Bowel Syndrome
  • Achalasia
  • Functional Abdominal Pain
  • Functional Bowel Disorders
  • Eosinophilic Esophagitis
  • Fecal Incontinence
  • Constipation
  • Intractable Constipation
  • Anorectal Malformations
  • Gastroesophageal Reflux Disease Surgery
  • Motility Disorders
  • Hirschsprung's Diease
  • Problem after Fundoplication

Departments

  • Gastroenterology, Hepatology and Nutrition

Languages

  • Spanish

Programs

  • Motility and Gastrointestinal Disorders Center
To schedule an appointment: Call 617-355-6055 or Request an Appointment

Experience and Education

Education

Medical School

University Nacional Autonoma de Mexico, 1981

Mexico City, Mexico

Internship

Boston City Hospital, 1981-1982

Boston, MA

Residency

Massachusetts General Hospital, 1983-1984

Boston, MA

Fellowship

Boston Children's Hospital, 1985-1987

Boston, MA

Certifications

  • Pediatrics, Pediatric Gastroenterology

Publications

Publications powered by Harvard Catalyst Profiles
  1. Varni JW, Shulman RJ, Self MM, Nurko S, Saps M, Saeed SA, Patel AS, Dark CV, Bendo CB, Pohl JF. Gastrointestinal symptoms predictors of health-related quality of life in pediatric patients with functional gastrointestinal disorders. Qual Life Res. 2016 Oct 14.
  2. Vadva Z, Nurko S, Hehn R, Vargas SO. Rectal Suction Biopsy in Patients With Previous Anorectal Surgery for Hirschsprung Disease. J Pediatr Gastroenterol Nutr. 2016 Oct 13.
  3. Ambartsumyan L, Flores A, Nurko S, Rodriguez L. Utility of Octreotide in Advancing Enteral Feeds in Children with Chronic Intestinal Pseudo-Obstruction. Paediatr Drugs. 2016 Oct; 18(5):387-92.
  4. Mudde AC, Lexmond WS, Blumberg RS, Nurko S, Fiebiger E. Eosinophilic esophagitis: published evidences for disease subtypes, indications for patient subpopulations, and how to translate patient observations to murine experimental models. World Allergy Organ J. 2016; 9:23.
  5. Hubbard CS, Becerra L, Heinz N, Ludwick A, Rasooly T, Wu R, Johnson A, Schechter NL, Borsook D, Nurko S. Abdominal Pain, the Adolescent and Altered Brain Structure and Function. PLoS One. 2016; 11(5):e0156545.
  6. Ambartsumyan L, Siddiqui A, Bauer S, Nurko S. Simultaneous urodynamic and anorectal manometry studies in children: insights into the relationship between the lower gastrointestinal and lower urinary tracts. Neurogastroenterol Motil. 2016 Jun; 28(6):924-33.
  7. Martinez EE, Douglas K, Nurko S, Mehta NM. Gastric Dysmotility in Critically Ill Children: Pathophysiology, Diagnosis, and Management. Pediatr Crit Care Med. 2015 Nov; 16(9):828-36.
  8. Varni JW, Nurko S, Shulman RJ, Self MM, Saps M, Bendo CB, Vaughan Dark C, Pohl JF. Pediatric Functional Constipation Gastrointestinal Symptom Profile Compared With Healthy Controls. J Pediatr Gastroenterol Nutr. 2015 Oct; 61(4):424-30.
  9. Varni JW, Shulman RJ, Self MM, Nurko S, Saps M, Saeed SA, Bendo CB, Patel AS, Dark CV, Zacur GM, Pohl JF. Symptom Profiles in Patients With Irritable Bowel Syndrome or Functional Abdominal Pain Compared With Healthy Controls. J Pediatr Gastroenterol Nutr. 2015 Sep; 61(3):323-9.
  10. Rodriguez L, Morley-Fletcher A, Souza A, Rosengaus L, Nurko S. Effect of anesthesia on gastroesophageal reflux in children: a study using BRAVO wireless pH study measurements. Neurogastroenterol Motil. 2015 Nov; 27(11):1553-8.
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  12. Rommel N, Omari TI, Selleslagh M, Kritas S, Cock C, Rosan R, Rodriguez L, Nurko S. High-resolution manometry combined with impedance measurements discriminates the cause of dysphagia in children. Eur J Pediatr. 2015 Dec; 174(12):1629-37.
  13. Hubert K, Sideridis G, Sherlock R, Queally J, Rosoklija I, Kringle G, Johnson K, Nurko S, Bauer S. Validation of a bowel dysfunction instrument for adolescents with spina bifida. J Pediatr Urol. 2015 Aug; 11(4):199.e1-7.
  14. Kovacic K, Sood MR, Mugie S, Di Lorenzo C, Nurko S, Heinz N, Ponnambalam A, Beesley C, Sanghavi R, Silverman AH. A multicenter study on childhood constipation and fecal incontinence: effects on quality of life. J Pediatr. 2015 Jun; 166(6):1482-7.e1.
  15. Varni JW, Franciosi JP, Shulman RJ, Saeed S, Nurko S, Neigut DA, Bendo CB, Patel AS, Self MM, Saps M, Zacur GM, Denham J, Dark CV, Pohl JF. PedsQL gastrointestinal symptoms scales and gastrointestinal worry scales in pediatric patients with inflammatory bowel disease in comparison with healthy controls. Inflamm Bowel Dis. 2015 May; 21(5):1115-24.
  16. Mallon D, Vernacchio L, Trudell E, Antonelli R, Nurko S, Leichtner AM, Lightdale JR. Shared care: a quality improvement initiative to optimize primary care management of constipation. Pediatrics. 2015 May; 135(5):e1300-7.
  17. Silverman AH, Berlin KS, Di Lorenzo C, Nurko S, Kamody RC, Ponnambalam A, Mugie S, Gorges C, Sanghavi R, Sood MR. Measuring Health-Related Quality of Life With the Parental Opinions of Pediatric Constipation Questionnaire. J Pediatr Psychol. 2015 Sep; 40(8):814-24.
  18. Sommers T, Corban C, Sengupta N, Jones M, Cheng V, Bollom A, Nurko S, Kelley J, Lembo A. Emergency department burden of constipation in the United States from 2006 to 2011. Am J Gastroenterol. 2015 Apr; 110(4):572-9.
  19. Park R, Mikami S, LeClair J, Bollom A, Lembo C, Sethi S, Lembo A, Jones M, Cheng V, Friedlander E, Nurko S. Inpatient burden of childhood functional GI disorders in the USA: an analysis of national trends in the USA from 1997 to 2009. Neurogastroenterol Motil. 2015 May; 27(5):684-92.
  20. Nurko S, Saps M. Treating constipation with prucalopride: one size does not fit all. Gastroenterology. 2014 Dec; 147(6):1214-6.
  21. Varni JW, Bendo CB, Nurko S, Shulman RJ, Self MM, Franciosi JP, Saps M, Pohl JF. Health-related quality of life in pediatric patients with functional and organic gastrointestinal diseases. J Pediatr. 2015 Jan; 166(1):85-90.
  22. Varni JW, Bendo CB, Denham J, Shulman RJ, Self MM, Neigut DA, Nurko S, Patel AS, Franciosi JP, Saps M, Verga B, Smith A, Yeckes A, Heinz N, Langseder A, Saeed S, Zacur GM, Pohl JF. PedsQL gastrointestinal symptoms module: feasibility, reliability, and validity. J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):347-55.
  23. Varni JW, Bendo CB, Denham J, Shulman RJ, Self MM, Neigut DA, Nurko S, Patel AS, Franciosi JP, Saps M, Yeckes A, Langseder A, Saeed S, Pohl JF. PedsQL™ Gastrointestinal Symptoms Scales and Gastrointestinal Worry Scales in pediatric patients with functional and organic gastrointestinal diseases in comparison to healthy controls. Qual Life Res. 2015 Feb; 24(2):363-78.
  24. Nurko S, Zimmerman LA. Evaluation and treatment of constipation in children and adolescents. Am Fam Physician. 2014 Jul 15; 90(2):82-90.
  25. Bromberg MH, Schechter NL, Nurko S, Zempsky WT, Schanberg LE. Persistent pain in chronically ill children without detectable disease activity. Pain Manag. 2014 May; 4(3):211-9.
  26. Ganesh M, Nurko S. Functional dyspepsia in children. Pediatr Ann. 2014 Apr; 43(4):e101-5.
  27. Lexmond WS, Neves JF, Nurko S, Olszak T, Exley MA, Blumberg RS, Fiebiger E. Involvement of the iNKT cell pathway is associated with early-onset eosinophilic esophagitis and response to allergen avoidance therapy. Am J Gastroenterol. 2014 May; 109(5):646-57.
  28. Rosen R, Amirault J, Giligan E, Khatwa U, Nurko S. Intraesophageal pressure recording improves the detection of cough during multichannel intraluminal impedance testing in children. J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):22-6.
  29. Mohammad S, Di Lorenzo C, Youssef NN, Miranda A, Nurko S, Hyman P, Saps M. Assessment of abdominal pain through global outcomes and recent FDA recommendations in children: are we ready for change? J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):46-50.
  30. Rosen R, Amirault J, Johnston N, Haver K, Khatwa U, Rubinstein E, Nurko S. The utility of endoscopy and multichannel intraluminal impedance testing in children with cough and wheezing. Pediatr Pulmonol. 2014 Nov; 49(11):1090-6.
  31. Ambartsumyan L, Rodriguez L, Morera C, Nurko S. Longitudinal and radial characteristics of intra-anal pressures in children using 3D high-definition anorectal manometry: new observations. Am J Gastroenterol. 2013 Dec; 108(12):1918-28.
  32. Ambartsumyan L, Nurko S. Review of organic causes of fecal incontinence in children: evaluation and treatment. Expert Rev Gastroenterol Hepatol. 2013 Sep; 7(7):657-67.
  33. Lexmond WS, Pardo M, Rooney K, Goettel JA, Snapper SB, Yen EH, Dehlink E, Nurko S, Fiebiger E. Elevated levels of leukotriene C4 synthase mRNA distinguish a subpopulation of eosinophilic oesophagitis patients. Clin Exp Allergy. 2013 Aug; 43(8):902-13.
  34. Zimmerman LA, Srinath AI, Goyal A, Bousvaros A, Ducharme P, Szigethy E, Nurko S. The overlap of functional abdominal pain in pediatric Crohn's disease. Inflamm Bowel Dis. 2013 Mar-Apr; 19(4):826-31.
  35. Rodriguez L, Roberts LD, LaRosa J, Heinz N, Gerszten R, Nurko S, Goldstein AM. Relationship between postprandial metabolomics and colon motility in children with constipation. Neurogastroenterol Motil. 2013 May; 25(5):420-6, e299.
  36. Rodriguez L, Diaz J, Nurko S. Safety and efficacy of cyproheptadine for treating dyspeptic symptoms in children. J Pediatr. 2013 Jul; 163(1):261-7.
  37. Rodriguez L, Nurko S, Flores A. Factors associated with successful decrease and discontinuation of antegrade continence enemas (ACE) in children with defecation disorders: a study evaluating the effect of ACE on colon motility. Neurogastroenterol Motil. 2013 Feb; 25(2):140-e81.
  38. Chogle A, Sztainberg M, Bass L, Youssef NN, Miranda A, Nurko S, Hyman P, Cocjin J, Di Lorenzo C, Saps M. Accuracy of pain recall in children. J Pediatr Gastroenterol Nutr. 2012 Sep; 55(3):288-91.
  39. Bannert C, Bidmon-Fliegenschnee B, Stary G, Hotzy F, Stift J, Nurko S, Szépfalusi Z, Fiebiger E, Dehlink E. Fc-epsilon-RI, the high affinity IgE-receptor, is robustly expressed in the upper gastrointestinal tract and modulated by mucosal inflammation. PLoS One. 2012; 7(7):e42066.
  40. Rodriguez L, Siddiqui A, Nurko S. Internal anal sphincter relaxation associated with bisacodyl-induced colonic high amplitude propagating contractions in children with constipation: a colo-anal reflex? Neurogastroenterol Motil. 2012 Nov; 24(11):1023-e545.
  41. Rodriguez L, Rosen R, Manfredi M, Nurko S. Endoscopic intrapyloric injection of botulinum toxin A in the treatment of children with gastroparesis: a retrospective, open-label study. Gastrointest Endosc. 2012 Feb; 75(2):302-9.
  42. Morera C, Nurko S. Heterogeneity of lower esophageal sphincter function in children with achalasia. J Pediatr Gastroenterol Nutr. 2012 Jan; 54(1):34-40.
  43. Rosen R, Johnston N, Hart K, Khatwa U, Nurko S. The presence of pepsin in the lung and its relationship to pathologic gastro-esophageal reflux. Neurogastroenterol Motil. 2012 Feb; 24(2):129-33, e84-5.
  44. Nurko S. Eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2011 Dec; 53 Suppl 2:S13-5.
  45. Nurko S. Extra-esophageal symptoms: how do we treat them? J Pediatr Gastroenterol Nutr. 2011 Dec; 53 Suppl 2:S22-3.
  46. Siddiqui A, Rosen R, Nurko S. Anorectal manometry may identify children with spinal cord lesions. J Pediatr Gastroenterol Nutr. 2011 Nov; 53(5):507-11.
  47. Nurko S. 50 years ago in the journal of pediatrics achalasia in children as a cause of recurrent pulmonary disease. J Pediatr. 2011 Oct; 159(4):632.
  48. Jadcherla SR, Nurko S. Esophageal disease in pediatrics. Ann N Y Acad Sci. 2011 Sep; 1232:401-4.
  49. Lexmond W, der Mee Jv, Ruiter F, Platzer B, Stary G, Yen EH, Dehlink E, Nurko S, Fiebiger E. Development and validation of a standardized ELISA for the detection of soluble Fc-epsilon-RI in human serum. J Immunol Methods. 2011 Oct 28; 373(1-2):192-9.
  50. Chumpitazi BP, Nurko S. Defecation disorders in children after surgery for Hirschsprung disease. J Pediatr Gastroenterol Nutr. 2011 Jul; 53(1):75-9.
  51. Mousa HM, Rosen R, Woodley FW, Orsi M, Armas D, Faure C, Fortunato J, O'Connor J, Skaggs B, Nurko S. [Esophageal impedance monitoring for gastroesophageal reflux]. Acta Gastroenterol Latinoam. 2011 Jun; 41(2):146-61.
  52. Raphael BP, Nurko S, Jiang H, Hart K, Kamin DS, Jaksic T, Duggan C. Cisapride improves enteral tolerance in pediatric short-bowel syndrome with dysmotility. J Pediatr Gastroenterol Nutr. 2011 May; 52(5):590-4.
  53. Siddiqui AA, Fishman SJ, Bauer SB, Nurko S. Long-term follow-up of patients after antegrade continence enema procedure. J Pediatr Gastroenterol Nutr. 2011 May; 52(5):574-80.
  54. Dehlink E, Platzer B, Baker AH, Larosa J, Pardo M, Dwyer P, Yen EH, Szépfalusi Z, Nurko S, Fiebiger E. A soluble form of the high affinity IgE receptor, Fc-epsilon-RI, circulates in human serum. PLoS One. 2011 Apr 22; 6(4):e19098.
  55. Sood MR, Di Lorenzo C, Hyams J, Miranda A, Simpson P, Mousa H, Nurko S. Beliefs and attitudes of general pediatricians and pediatric gastroenterologists regarding functional gastrointestinal disorders: a survey study. Clin Pediatr (Phila). 2011 Oct; 50(10):891-6.
  56. Rosen R, Hart K, Nurko S. Does reflux monitoring with multichannel intraluminal impedance change clinical decision making? J Pediatr Gastroenterol Nutr. 2011 Apr; 52(4):404-7.
  57. Chiou E, Rosen R, Nurko S. Effect of different pH criteria on dual-sensor pH monitoring in the evaluation of supraesophageal gastric reflux in children. J Pediatr Gastroenterol Nutr. 2011 Apr; 52(4):399-403.
  58. Mousa HM, Rosen R, Woodley FW, Orsi M, Armas D, Faure C, Fortunato J, O'connor J, Skaggs B, Nurko S. Esophageal impedance monitoring for gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):129-39.
  59. Yen EH, Hornick JL, Dehlink E, Dokter M, Baker A, Fiebiger E, Nurko S. Comparative analysis of FceRI expression patterns in patients with eosinophilic and reflux esophagitis. J Pediatr Gastroenterol Nutr. 2010 Nov; 51(5):584-92.
  60. Dehlink E, Baker AH, Yen E, Nurko S, Fiebiger E. Relationships between levels of serum IgE, cell-bound IgE, and IgE-receptors on peripheral blood cells in a pediatric population. PLoS One. 2010 Aug 16; 5(8):e12204.
  61. Rosen R, Levine P, Lewis J, Mitchell P, Nurko S. Reflux events detected by pH-MII do not determine fundoplication outcome. J Pediatr Gastroenterol Nutr. 2010 Mar; 50(3):251-5.
  62. Mallory LA, Shaw JG, Burgess SL, Estrella E, Nurko S, Burpee TM, Agus MS, Darras BT, Kunkel LM, Kang PB. Congenital myasthenic syndrome with episodic apnea. Pediatr Neurol. 2009 Jul; 41(1):42-5.
  63. Chumpitazi BP, Fishman SJ, Nurko S. Long-term clinical outcome after botulinum toxin injection in children with nonrelaxing internal anal sphincter. Am J Gastroenterol. 2009 Apr; 104(4):976-83.
  64. Nurko S. The tip of the iceberg: the prevalence of functional gastrointestinal diseases in children. J Pediatr. 2009 Mar; 154(3):313-5.
  65. Modi BP, Ching YA, Langer M, Donovan K, Fauza DO, Kim HB, Jaksic T, Nurko S. Preservation of intestinal motility after the serial transverse enteroplasty procedure in a large animal model of short bowel syndrome. J Pediatr Surg. 2009 Jan; 44(1):229-35; discussion 235.
  66. Nurko S, Di Lorenzo C. Functional abdominal pain: time to get together and move forward. J Pediatr Gastroenterol Nutr. 2008 Nov; 47(5):679-80.
  67. Pensabene L, Nurko S. Approach to the child who has persistent dysphagia after surgical treatment for esophageal achalasia. J Pediatr Gastroenterol Nutr. 2008 Jul; 47(1):92-7.
  68. Rosen R, Furuta G, Fritz J, Donovan K, Nurko S. Role of acid and nonacid reflux in children with eosinophilic esophagitis compared with patients with gastroesophageal reflux and control patients. J Pediatr Gastroenterol Nutr. 2008 May; 46(5):520-3.
  69. Rosen R, Fritz J, Nurko A, Simon D, Nurko S. Lipid-laden macrophage index is not an indicator of gastroesophageal reflux-related respiratory disease in children. Pediatrics. 2008 Apr; 121(4):e879-84.
  70. Nurko S, Youssef NN, Sabri M, Langseder A, McGowan J, Cleveland M, Di Lorenzo C. PEG3350 in the treatment of childhood constipation: a multicenter, double-blinded, placebo-controlled trial. J Pediatr. 2008 Aug; 153(2):254-61, 261.e1.
  71. Chumpitazi B, Nurko S. Pediatric gastrointestinal motility disorders: challenges and a clinical update. Gastroenterol Hepatol (N Y). 2008 Feb; 4(2):140-8.
  72. Nurko S, Rosen R. Esophageal dysmotility in patients who have eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2008 Jan; 18(1):73-89; ix.
  73. Rosen R, Lord C, Nurko S. The sensitivity of multichannel intraluminal impedance and the pH probe in the evaluation of gastroesophageal reflux in children. Clin Gastroenterol Hepatol. 2006 Feb; 4(2):167-72.
  74. Nurko S. What's the value of diagnostic tools in defecation disorders? J Pediatr Gastroenterol Nutr. 2005 Sep; 41 Suppl 1:S53-5.
  75. Nurko S, Rosen R. Use of multi-channel intraluminal impedance (MII) in the evaluation of children with respiratory symptoms: a new phenomenon? J Pediatr Gastroenterol Nutr. 2005 Aug; 41(2):166-8.
  76. Benninga M, Candy DC, Catto-Smith AG, Clayden G, Loening-Baucke V, Di Lorenzo C, Nurko S, Staiano A. The Paris Consensus on Childhood Constipation Terminology (PACCT) Group. J Pediatr Gastroenterol Nutr. 2005 Mar; 40(3):273-5.
  77. Chitkara DK, Fortunato C, Nurko S. Esophageal motor activity in children with gastro-esophageal reflux disease and esophagitis. J Pediatr Gastroenterol Nutr. 2005 Jan; 40(1):70-5.
  78. Rosen R, Nurko S. The importance of multichannel intraluminal impedance in the evaluation of children with persistent respiratory symptoms. Am J Gastroenterol. 2004 Dec; 99(12):2452-8.
  79. Rosen R, Buonomo C, Andrade R, Nurko S. Incidence of spinal cord lesions in patients with intractable constipation. J Pediatr. 2004 Sep; 145(3):409-11.
  80. Fishman L, Lenders C, Fortunato C, Noonan C, Nurko S. Increased prevalence of constipation and fecal soiling in a population of obese children. J Pediatr. 2004 Aug; 145(2):253-4.
  81. Prasad C, Nurko S, Borovoy J, Korson MS. The importance of gut motility in the metabolic control of propionic acidemia. J Pediatr. 2004 Apr; 144(4):532-5.
  82. Chitkara DK, Fortunato C, Nurko S. Prolonged monitoring of esophageal motor function in healthy children. J Pediatr Gastroenterol Nutr. 2004 Feb; 38(2):192-7.
  83. Köhler H, Nurko S, Glickman J, Furuta GT. Acute myeloid leukemia presenting as non-neutropenic colitis in an infant. J Pediatr Gastroenterol Nutr. 2003 Nov; 37(5):631-3.
  84. Ciamarra P, Nurko S, Barksdale E, Fishman S, Di Lorenzo C. Internal anal sphincter achalasia in children: clinical characteristics and treatment with Clostridium botulinum toxin. J Pediatr Gastroenterol Nutr. 2003 Sep; 37(3):315-9.
  85. Rosen R, Nurko S, Furuta GT. Impeding gastroesophageal refluxate: a new application of an old medication. Gastroenterology. 2003 Sep; 125(3):984-5; discussion 985-6.
  86. Morera C, Nurko S. Rectal manometry in patients with isolated sacral agenesis. J Pediatr Gastroenterol Nutr. 2003 Jul; 37(1):47-52.
  87. Fishman L, Rappaport L, Schonwald A, Nurko S. Trends in referral to a single encopresis clinic over 20 years. Pediatrics. 2003 May; 111(5 Pt 1):e604-7.
  88. Chitkara DK, Nurko S, Shoffner JM, Buie T, Flores A. Abnormalities in gastrointestinal motility are associated with diseases of oxidative phosphorylation in children. Am J Gastroenterol. 2003 Apr; 98(4):871-7.
  89. Kim HB, Fauza D, Garza J, Oh JT, Nurko S, Jaksic T. Serial transverse enteroplasty (STEP): a novel bowel lengthening procedure. J Pediatr Surg. 2003 Mar; 38(3):425-9.
  90. Heuschkel RB, Fletcher K, Hill A, Buonomo C, Bousvaros A, Nurko S. Isolated neonatal swallowing dysfunction: a case series and review of the literature. Dig Dis Sci. 2003 Jan; 48(1):30-5.
  91. Fox VL, Nurko S, Furuta GT. Eosinophilic esophagitis: it's not just kid's stuff. Gastrointest Endosc. 2002 Aug; 56(2):260-70.
  92. Di Lorenzo C, Hillemeier C, Hyman P, Loening-Baucke V, Nurko S, Rosenberg A, Taminiau J. Manometry studies in children: minimum standards for procedures. Neurogastroenterol Motil. 2002 Aug; 14(4):411-20.
  93. Rakhit A, Nurko S, Gauvreau K, Mayer JE, Blume ED. Gastrointestinal complications after pediatric cardiac transplantation. J Heart Lung Transplant. 2002 Jul; 21(7):751-9.
  94. Teitelbaum JE, Fox VL, Twarog FJ, Nurko S, Antonioli D, Gleich G, Badizadegan K, Furuta GT. Eosinophilic esophagitis in children: immunopathological analysis and response to fluticasone propionate. Gastroenterology. 2002 May; 122(5):1216-25.
  95. Fishman L, Rappaport L, Cousineau D, Nurko S. Early constipation and toilet training in children with encopresis. J Pediatr Gastroenterol Nutr. 2002 Apr; 34(4):385-8.
  96. Lyons J, Rauh-Pfeiffer A, Ming-Yu Y, Lu XM, Zurakowski D, Curley M, Collier S, Duggan C, Nurko S, Thompson J, Ajami A, Borgonha S, Young VR, Castillo L. Cysteine metabolism and whole blood glutathione synthesis in septic pediatric patients. Crit Care Med. 2001 Apr; 29(4):870-7.
  97. Fishman SJ, Islam S, Buonomo C, Nurko S. Nonfixation of an atretic colon predicts Hirschsprung's disease. J Pediatr Surg. 2001 Jan; 36(1):202-4.
  98. Furuta GT, Nurko S, Bousvaros A, Antonioli D, Badizadegan K. The spectrum of pediatric gastroesophageal reflux. JAMA. 2000 Dec 27; 284(24):3125-6.
  99. Nurko S. Advances in the management of pediatric constipation. Curr Gastroenterol Rep. 2000 Jun; 2(3):234-40.
  100. Nurko S. The efficacy of cisapride: what is needed for digestion? J Pediatr Gastroenterol Nutr. 2000 Mar; 30(3):230-1.
  101. Nurko S, Garcia-Aranda JA, Worona LB, Zlochisty O. Cisapride for the treatment of constipation in children: A double-blind study. J Pediatr. 2000 Jan; 136(1):35-40.
  102. Nurko S. Cisapride for the treatment of gastroesophageal reflux disease in children. J Pediatr Gastroenterol Nutr. 1999 Jul; 29(1):7.
  103. Borovoy J, Furuta L, Nurko S. Benefit of uncooked cornstarch in the management of children with dumping syndrome fed exclusively by gastrostomy. Am J Gastroenterol. 1998 May; 93(5):814-8.
  104. Siafakas C, Fox VL, Nurko S. Use of octreotide for the treatment of severe gastrointestinal bleeding in children. J Pediatr Gastroenterol Nutr. 1998 Mar; 26(3):356-9.
  105. Duggan C, Nurko S. "Feeding the gut": the scientific basis for continued enteral nutrition during acute diarrhea. J Pediatr. 1997 Dec; 131(6):801-8.
  106. Nurko S, García-Aranda JA, Fishbein E, Pérez-Zúñiga MI. Successful use of a chicken-based diet for the treatment of severely malnourished children with persistent diarrhea: a prospective, randomized study. J Pediatr. 1997 Sep; 131(3):405-12.
  107. Nurko S. Botulinum toxin for achalasia: are we witnessing the birth of a new era? J Pediatr Gastroenterol Nutr. 1997 Apr; 24(4):447-9.
  108. Nurko S, Garcia-Aranda JA, Guerrero VY, Worona LB. Treatment of intractable constipation in children: experience with cisapride. J Pediatr Gastroenterol Nutr. 1996 Jan; 22(1):38-44.
  109. Shamberger RC, Lillehei CW, Nurko S, Winter HS. Anorectal function in children after ileoanal pull-through. J Pediatr Surg. 1994 Feb; 29(2):329-32; discussion 332-3.
  110. Nurko S, Rattan S. Role of neuropeptide Y in opossum internal anal sphincter. Am J Physiol. 1990 Jan; 258(1 Pt 1):G59-64.
  111. Nurko S, Dunn BM, Rattan S. Peptide histidine isoleucine and vasoactive intestinal polypeptide cause relaxation of opossum internal anal sphincter via two distinct receptors. Gastroenterology. 1989 Feb; 96(2 Pt 1):403-13.
  112. Nurko S, Rattan S. Role of vasoactive intestinal polypeptide in the internal anal sphincter relaxation of the opossum. J Clin Invest. 1988 Apr; 81(4):1146-53.
  113. Peña A, Pérez L, Nurko S, Dorenbaum D. Pectus carinatum and pectus excavatum: are they the same disease? Am Surg. 1981 May; 47(5):215-8.
  114. Lazar Moussali F, Dorenbaum D, Nurko S. [Neurogenic bladder in children. Analysis of the most adequate method for the treatment in our area (review of 6 years of experience at the Hospital del Niño DIF)]. Actas Urol Esp. 1979 Nov-Dec; 3(6):337-44.
  115. Nurko S, Scott SM. Coexistence of constipation and incontinence in children and adults. Best Pract Res Clin Gastroenterol. 2011 Feb; 25(1):29-41.
  116. Nurko S, Teitelbaum JE, Husain K, Buonomo C, Fox VL, Antonioli D, Fortunato C, Badizadegan K, Furuta GT. Association of Schatzki ring with eosinophilic esophagitis in children. J Pediatr Gastroenterol Nutr. 2004 Apr; 38(4):436-41.
  117. Fox VL, Nurko S, Teitelbaum JE, Badizadegan K, Furuta GT. High-resolution EUS in children with eosinophilic "allergic" esophagitis. Gastrointest Endosc. 2003 Jan; 57(1):30-6.
  118. Bloom DA, Buonomo C, Fishman SJ, Furuta G, Nurko S. Allergic colitis: a mimic of Hirschsprung disease. Pediatr Radiol. 1999 Jan; 29(1):37-41.
  119. Hadigan C, Fishman SJ, Connolly LP, Treves ST, Nurko S. Stimulation with fatty meal (Lipomul) to assess gallbladder emptying in children with chronic acalculous cholecystitis. J Pediatr Gastroenterol Nutr. 2003 Aug; 37(2):178-82.
  120. Pensabene L, Buonomo C, Fishman L, Chitkara D, Nurko S. Lack of utility of abdominal x-rays in the evaluation of children with constipation: comparison of different scoring methods. J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):155-9.
  121. Simanovsky N, Buonomo C, Nurko S. The infant with chronic vomiting: the value of the upper GI series. Pediatr Radiol. 2002 Aug; 32(8):549-50; discussion 551.
  122. Rosen R, Johnston N, Hart K, Khatwa U, Katz E, Nurko S. Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders. J Pediatr. 2011 Sep; 159(3):504-6.
  123. Buckley K, Buonomo C, Husain K, Nurko S. Schatzki ring in children and young adults: clinical and radiologic findings. Pediatr Radiol. 1998 Nov; 28(11):884-6.
  124. Vazquez JL, Buonomo C, Nurko S. Barrett's esophagus in a teenager with a ringed esophagus. Pediatr Radiol. 1999 Aug; 29(8):641.
  125. Chiou E, Rosen R, Jiang H, Nurko S. Diagnosis of supra-esophageal gastric reflux: correlation of oropharyngeal pH with esophageal impedance monitoring for gastro-esophageal reflux. Neurogastroenterol Motil. 2011 Aug; 23(8):717-e326.
  126. Nurko S, Rosen R, Furuta GT. Esophageal dysmotility in children with eosinophilic esophagitis: a study using prolonged esophageal manometry. Am J Gastroenterol. 2009 Dec; 104(12):3050-7.
  127. Orange JS, Brodeur SR, Jain A, Bonilla FA, Schneider LC, Kretschmer R, Nurko S, Rasmussen WL, Köhler JR, Gellis SE, Ferguson BM, Strominger JL, Zonana J, Ramesh N, Ballas ZK, Geha RS. Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations. J Clin Invest. 2002 Jun; 109(11):1501-9.
  128. Teitelbaum JE, Berde CB, Nurko S, Buonomo C, Perez-Atayde AR, Fox VL. Diagnosis and management of MNGIE syndrome in children: case report and review of the literature. J Pediatr Gastroenterol Nutr. 2002 Sep; 35(3):377-83.
  129. Guzman C, Bousvaros A, Buonomo C, Nurko S. Intraduodenal hematoma complicating intestinal biopsy: case reports and review of the literature. Am J Gastroenterol. 1998 Dec; 93(12):2547-50.
  130. Saps M, Youssef N, Miranda A, Nurko S, Hyman P, Cocjin J, Di Lorenzo C. Multicenter, randomized, placebo-controlled trial of amitriptyline in children with functional gastrointestinal disorders. Gastroenterology. 2009 Oct; 137(4):1261-9.
  131. Reid JR, Buonomo C, Moreira C, Kozakevich H, Nurko SJ. The barium enema in constipation: comparison with rectal manometry and biopsy to exclude Hirschsprung's disease after the neonatal period. Pediatr Radiol. 2000 Oct; 30(10):681-4.
  132. Chiou E, Nurko S. Management of functional abdominal pain and irritable bowel syndrome in children and adolescents. Expert Rev Gastroenterol Hepatol. 2010 Jun; 4(3):293-304.
  133. Berde C, Nurko S. Opioid side effects--mechanism-based therapy. N Engl J Med. 2008 May 29; 358(22):2400-2.
  134. Pai SY, Levy O, Jabara HH, Glickman JN, Stoler-Barak L, Sachs J, Nurko S, Orange JS, Geha RS. Allogeneic transplantation successfully corrects immune defects, but not susceptibility to colitis, in a patient with nuclear factor-kappaB essential modulator deficiency. J Allergy Clin Immunol. 2008 Dec; 122(6):1113-1118.e1.
  135. Baker SS, Liptak GS, Colletti RB, Croffie JM, Di Lorenzo C, Ector W, Nurko S. Constipation in infants and children: evaluation and treatment. A medical position statement of the North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr. 1999 Nov; 29(5):612-26.
  136. Varni JW, Bendo CB, Shulman RJ, Self MM, Nurko S, Franciosi JP, Saps M, Saeed S, Zacur GM, Vaughan Dark C, Pohl JF. Interpretability of the PedsQL™ Gastrointestinal Symptoms Scales and Gastrointestinal Worry Scales in Pediatric Patients With Functional and Organic Gastrointestinal Diseases. J Pediatr Psychol. 2015 Jul; 40(6):591-601.
  137. Lexmond WS, Hu L, Pardo M, Heinz N, Rooney K, LaRosa J, Dehlink E, Fiebiger E, Nurko S. Accuracy of digital mRNA profiling of oesophageal biopsies as a novel diagnostic approach to eosinophilic oesophagitis. Clin Exp Allergy. 2015 Aug; 45(8):1317-27.
  138. Ganesh M, Hertzberg A, Nurko S, Needleman H, Rosen R. Acid Rather Than Nonacid Reflux Burden Is a Predictor of Tooth Erosion. J Pediatr Gastroenterol Nutr. 2016 Feb; 62(2):309-13.
  139. Chiou E, Nurko S. Functional abdominal pain and irritable bowel syndrome in children and adolescents. Therapy. 2011 May 1; 8(3):315-331.
  140. Varni JW, Shulman RJ, Self MM, Saeed SA, Patel AS, Nurko S, Neigut DA, Saps M, Franciosi JP, Denham JM, Zacur GM, Dark CV, Bendo CB, Pohl JF. Gastrointestinal Symptoms Predictors of Health-Related Quality of Life in Patients With Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2016 Dec; 63(6):e186-e192.
  141. Venturelli N, Lexmond WS, Ohsaki A, Nurko S, Karasuyama H, Fiebiger E, Oyoshi MK. Allergic skin sensitization promotes eosinophilic esophagitis through the IL-33-basophil axis in mice. J Allergy Clin Immunol. 2016 Nov; 138(5):1367-1380.e5.
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