Michael Landzberg

Michael Landzberg, MD

Associate in Cardiology; Associate Director, Adult Pulmonary Hypertension Program; Director, Boston Adult Congenital Heart (BACH)

Assistant Professor of Medicine, Harvard Medical School

Medical Services

Specialties

  • Adult Pulmonary Hypertension
  • Adult Congenital Heart Disease
  • Cardiology

Departments

  • Cardiology

Programs

  • Boston Adult Congenital Heart Service
  • Pulmonary Hypertension Program
  • Cardiac Catheterization Labs
  • Adult Congenital Heart Service
  • Cardiovascular Program
To schedule an appointment: Call 617-355-6508 or Request an Appointment

Experience and Education

Education

Undergraduate

Columbia University, 1981

New York, NY

Medical School

Harvard Medical School, 1985

Boston, MA

Internship

Columbia University, 1988

New York, NY

Residency

Columbia University, 1988-1989

New York, NY

Fellowship

Brigham and Women's Hospital, 1989-1992

Boston, MA

Certifications

  • Internal Medicine, Cardiovascular Disease

Professional History

Publications

Publications powered by Harvard Catalyst
  1. Gurvitz M, Burns KM, Brindis R, Broberg CS, Daniels CJ, Fuller SM, Honein MA, Khairy P, Kuehl KS, Landzberg MJ, Mahle WT, Mann DL, Marelli A, Newburger JW, Pearson GD, Starling RC, Tringali GR, Valente AM, Wu JC, Califf RM. Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group. J Am Coll Cardiol. 2016 Apr 26; 67(16):1956-64.
  2. Opotowsky AR, Baraona F, Owumi J, Loukas B, Singh MN, Valente AM, Wu F, Cheng S, Veldtman G, Rimm EB, Landzberg MJ. Galectin-3 Is Elevated and Associated With Adverse Outcomes in Patients With Single-Ventricle Fontan Circulation. J Am Heart Assoc. 2016; 5(1).
  3. Roldan T, Landzberg MJ, Deicicchi DJ, Atay JK, Waxman AB. Anticoagulation in patients with pulmonary arterial hypertension: An update on current knowledge. J Heart Lung Transplant. 2016 Feb; 35(2):151-64.
  4. Ruiz CE, Kliger C, Perk G, Maisano F, Cabalka AK, Landzberg M, Rihal C, Kronzon I. Transcatheter Therapies for the Treatment of Valvular and Paravalvular Regurgitation in Acquired and Congenital Valvular Heart Disease. J Am Coll Cardiol. 2015 Jul 14; 66(2):169-83.
  5. Partington SL, Valente AM, Landzberg M, Grant F, Di Carli MF, Dorbala S. Clinical applications of radionuclide imaging in the evaluation and management of patients with congenital heart disease. J Nucl Cardiol. 2016 Feb; 23(1):45-63.
  6. Daniels CJ, Landzberg MJ, Beekman RH. Structural heart disease: tetralogy, transposition, and truncus, too? J Am Coll Cardiol. 2015 May 26; 65(20):2260-1.
  7. Goossens E, Fernandes SM, Landzberg MJ, Moons P. Implementation of the American College of Cardiology/American Heart Association 2008 Guidelines for the Management of Adults With Congenital Heart Disease. Am J Cardiol. 2015 Aug 1; 116(3):452-7.
  8. Webb G, Mulder BJ, Aboulhosn J, Daniels CJ, Elizari MA, Hong G, Horlick E, Landzberg MJ, Marelli AJ, O'Donnell CP, Oechslin EN, Pearson DD, Pieper EP, Saxena A, Schwerzmann M, Stout KK, Warnes CA, Khairy P. The care of adults with congenital heart disease across the globe: Current assessment and future perspective: A position statement from the International Society for Adult Congenital Heart Disease (ISACHD). Int J Cardiol. 2015 Sep 15; 195:326-33.
  9. Wu FM, Jonas MM, Opotowsky AR, Harmon A, Raza R, Ukomadu C, Landzberg MJ, Singh MN, Valente AM, Egidy Assenza G, Perez-Atayde AR. Portal and centrilobular hepatic fibrosis in Fontan circulation and clinical outcomes. J Heart Lung Transplant. 2015 Jul; 34(7):883-91.
  10. Buber J, McElhinney DB, Valente AM, Marshall AC, Landzberg MJ. Tricuspid valve regurgitation in congenitally corrected transposition of the great arteries and a left ventricle to pulmonary artery conduit. Ann Thorac Surg. 2015 Apr; 99(4):1348-56.
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  12. Opotowsky AR, Moko LE, Ginns J, Rosenbaum M, Greutmann M, Aboulhosn J, Hageman A, Kim Y, Deng LX, Grewal J, Zaidi AN, Almansoori G, Oechslin E, Earing M, Landzberg MJ, Singh MN, Wu F, Vaidya A. Pheochromocytoma and paraganglioma in cyanotic congenital heart disease. J Clin Endocrinol Metab. 2015 Apr; 100(4):1325-34.
  13. Nathan AS, Loukas B, Moko L, Wu F, Rhodes J, Rathod RH, Systrom DM, Ubeda Tikkanen A, Shafer K, Lewis GD, Landzberg MJ, Opotowsky AR. Exercise oscillatory ventilation in patients with Fontan physiology. Circ Heart Fail. 2015 Mar; 8(2):304-11.
  14. Landzberg MJ. The impact of IMPACT: a game changer for congenital cardiology. J Am Coll Cardiol. 2014 Dec 16; 64(23):2452-4.
  15. Santos M, Systrom D, Epstein SE, John A, Ruiz G, Landzberg MJ, Opotowsky AR. Impaired exercise capacity following atrial septal defect closure: an invasive study of the right heart and pulmonary circulation. Pulm Circ. 2014 Dec; 4(4):630-7.
  16. Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, Gomez Sanchez MA, Kumar RK, Landzberg M, Machado RF, Olschewski H, Robbins IM, Souza R. [Updated clinical classification of pulmonary hypertension]. Turk Kardiyol Dern Ars. 2014 Oct; 42 Suppl 1:45-54.
  17. Wu FM, Emani SM, Landzberg MJ, Valente AM. Rare case of undiagnosed supracardiac total anomalous pulmonary venous return in an adult. Circulation. 2014 Sep 30; 130(14):1205-7.
  18. Gatzoulis MA, Beghetti M, Landzberg MJ, Galiè N. Pulmonary arterial hypertension associated with congenital heart disease: recent advances and future directions. Int J Cardiol. 2014 Dec 15; 177(2):340-7.
  19. Saboo SS, Juan YH, Khandelwal A, George E, Steigner ML, Landzberg M, Rybicki FJ. MDCT of congenital coronary artery fistulas. AJR Am J Roentgenol. 2014 Sep; 203(3):W244-52.
  20. Buber J, Assenza GE, Huang A, Valente AM, Emani SM, Gauvreau K, Marshal AC, McElhinney DB, Landzberg MJ. Durability of large diameter right ventricular outflow tract conduits in adults with congenital heart disease. Int J Cardiol. 2014 Aug 20; 175(3):455-63.
  21. Rozenblum R, Gianola A, Ionescu-Ittu R, Verstappen A, Landzberg M, Gurvitz M, Jenkins K, Bates DW, Marelli AJ. Clinicians' perspectives on patient satisfaction in adult congenital heart disease clinics--a dimension of health care quality whose time has come. Congenit Heart Dis. 2015 Mar-Apr; 10(2):128-36.
  22. Udell JA, Opotowsky AR, Khairy P, Silversides CK, Gladstone DJ, O'Gara PT, Landzberg MJ. Patent foramen ovale closure vs medical therapy for stroke prevention: meta-analysis of randomized trials and review of heterogeneity in meta-analyses. Can J Cardiol. 2014 Oct; 30(10):1216-24.
  23. Opotowsky AR, Landzberg MJ, Earing MG, Wu FM, Triedman JK, Casey A, Ericson DA, Systrom D, Paridon SM, Rhodes J. Abnormal spirometry after the Fontan procedure is common and associated with impaired aerobic capacity. Am J Physiol Heart Circ Physiol. 2014 Jul 1; 307(1):H110-7.
  24. Sanborn TA, Tcheng JE, Anderson HV, Chambers CE, Cheatham SL, DeCaro MV, Durack JC, Everett AD, Gordon JB, Hammond WE, Hijazi ZM, Kashyap VS, Knudtson M, Landzberg MJ, Martinez-Rios MA, Riggs LA, Sim KH, Slotwiner DJ, Solomon H, Szeto WY, Weiner BH, Weintraub WS, Windle JR. ACC/AHA/SCAI 2014 health policy statement on structured reporting for the cardiac catheterization laboratory: a report of the American College of Cardiology Clinical Quality Committee. J Am Coll Cardiol. 2014 Jun 17; 63(23):2591-623.
  25. Sanborn TA, Tcheng JE, Anderson HV, Chambers CE, Cheatham SL, DeCaro MV, Durack JC, Everett AD, Gordon JB, Hammond WE, Hijazi ZM, Kashyap VS, Knudtson M, Landzberg MJ, Martinez-Rios MA, Riggs LA, Sim KH, Slotwiner DJ, Solomon H, Szeto WY, Weiner BH, Weintraub WS, Windle JR. ACC/AHA/SCAI 2014 health policy statement on structured reporting for the cardiac catheterization laboratory: a report of the American College of Cardiology Clinical Quality Committee. Circulation. 2014 Jun 17; 129(24):2578-609.
  26. Webb G, Landzberg MJ, Daniels CJ. Specialized adult congenital heart care saves lives. Circulation. 2014 May 6; 129(18):1795-6.
  27. Wu FM, Opotowsky AR, Raza R, Harney S, Ukomadu C, Landzberg MJ, Valente AM, Breitbart RE, Singh MN, Gauvreau K, Jonas MM. Transient elastography may identify Fontan patients with unfavorable hemodynamics and advanced hepatic fibrosis. Congenit Heart Dis. 2014 Sep-Oct; 9(5):438-47.
  28. Opotowsky AR, Landzberg MJ, Beghetti M. The exceptional and far-flung manifestations of heart failure in Eisenmenger syndrome. Heart Fail Clin. 2014 Jan; 10(1):91-104.
  29. Opotowsky AR, Landzberg MJ. Evolving perspectives on heart failure in adults with congenital heart disease. Preface. Heart Fail Clin. 2014 Jan; 10(1):xv-xvi.
  30. Fernandes SM, O'Sullivan-Oliveira J, Landzberg MJ, Khairy P, Melvin P, Sawicki GS, Ziniel S, Kenney LB, Garvey KC, Sobota A, O'Brien R, Nigrovic PA, Sharma N, Fishman LN. Transition and transfer of adolescents and young adults with pediatric onset chronic disease: the patient and parent perspective. J Pediatr Rehabil Med. 2014; 7(1):43-51.
  31. Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, Gomez Sanchez MA, Krishna Kumar R, Landzberg M, Machado RF, Olschewski H, Robbins IM, Souza R. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D34-41.
  32. Cotts T, Khairy P, Opotowsky AR, John AS, Valente AM, Zaidi AN, Cook SC, Aboulhosn J, Ting JG, Gurvitz M, Landzberg MJ, Verstappen A, Kay J, Earing M, Franklin W, Kogon B, Broberg CS. Clinical research priorities in adult congenital heart disease. Int J Cardiol. 2014 Feb 15; 171(3):351-60.
  33. Mehra MR, Park MH, Landzberg MJ, Lala A, Waxman AB. Right heart failure: toward a common language. Pulm Circ. 2013 Dec; 3(4):963-7.
  34. Opotowsky AR, Santos M, Maron BA, Afilalo J, Waxman AB, Landzberg MJ, Forfia PR. Towards widespread noninvasive assessment of pulmonary vascular resistance in clinical practice. J Am Soc Echocardiogr. 2014 Jan; 27(1):108-9.
  35. Valente AM, Gauvreau K, Assenza GE, Babu-Narayan SV, Schreier J, Gatzoulis MA, Groenink M, Inuzuka R, Kilner PJ, Koyak Z, Landzberg MJ, Mulder B, Powell AJ, Wald R, Geva T. Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of Fallot enrolled in the INDICATOR cohort. Heart. 2014 Feb; 100(3):247-53.
  36. Mehra MR, Park MH, Landzberg MJ, Lala A, Waxman AB. Right heart failure: toward a common language. J Heart Lung Transplant. 2014 Feb; 33(2):123-6.
  37. Valente AM, Lewis M, Vaziri SM, Bautista-Hernandez V, Harmon A, Kim Y, Wu FM, Joyce C, Loyola H, Mayer JE, Bacha E, Landzberg MJ. Outcomes of adolescents and adults undergoing primary Fontan procedure. Am J Cardiol. 2013 Dec 15; 112(12):1938-42.
  38. Ubeda Tikkanen A, Opotowsky AR, Bhatt AB, Landzberg MJ, Rhodes J. Physical activity is associated with improved aerobic exercise capacity over time in adults with congenital heart disease. Int J Cardiol. 2013 Oct 12; 168(5):4685-91.
  39. Potter BJ, Leong-Sit P, Fernandes SM, Feifer A, Mayer JE, Triedman JK, Walsh EP, Landzberg MJ, Khairy P. Effect of aspirin and warfarin therapy on thromboembolic events in patients with univentricular hearts and Fontan palliation. Int J Cardiol. 2013 Oct 9; 168(4):3940-3.
  40. Landzberg MJ, Khairy P. Patent foramen ovale: when is intervention warranted? Can J Cardiol. 2013 Jul; 29(7):890-2.
  41. Clair M, Fernandes SM, Khairy P, Graham DA, Krieger EV, Opotowsky AR, Singh MN, Colan SD, Meijboom EJ, Landzberg MJ. Aortic valve dysfunction and aortic dilation in adults with coarctation of the aorta. Congenit Heart Dis. 2014 May-Jun; 9(3):235-43.
  42. Buber J, Bergersen L, Lock JE, Gauvreau K, Esch JJ, Landzberg MJ, Valente AM, Sandora TJ, Marshall AC. Bloodstream infections occurring in patients with percutaneously implanted bioprosthetic pulmonary valve: a single-center experience. Circ Cardiovasc Interv. 2013 Jun; 6(3):301-10.
  43. Opotowsky AR, Clair M, Afilalo J, Landzberg MJ, Waxman AB, Moko L, Maron BA, Vaidya A, Forfia PR. A simple echocardiographic method to estimate pulmonary vascular resistance. Am J Cardiol. 2013 Sep 15; 112(6):873-82.
  44. Valente AM, Landzberg MJ, Gianola A, Harmon AJ, Cook S, Ting JG, Stout K, Kuehl K, Khairy P, Kay JD, Earing M, Houser L, Broberg C, Milliren C, Opotowsky AR, Webb G, Verstappen A, Gurvitz M. Improving heart disease knowledge and research participation in adults with congenital heart disease (the Health, Education and Access Research Trial: HEART-ACHD). Int J Cardiol. 2013 Oct 9; 168(4):3236-40.
  45. Rhodes J, Ubeda-Tikkanen A, Clair M, Fernandes SM, Graham DA, Milliren CE, Daly KP, Mullen MP, Landzberg MJ. Effect of inhaled iloprost on the exercise function of Fontan patients: a demonstration of concept. Int J Cardiol. 2013 Oct 3; 168(3):2435-40.
  46. Gurvitz M, Valente AM, Broberg C, Cook S, Stout K, Kay J, Ting J, Kuehl K, Earing M, Webb G, Houser L, Opotowsky A, Harmon A, Graham D, Khairy P, Gianola A, Verstappen A, Landzberg M. Prevalence and predictors of gaps in care among adult congenital heart disease patients: HEART-ACHD (The Health, Education, and Access Research Trial). J Am Coll Cardiol. 2013 May 28; 61(21):2180-4.
  47. Esch JJ, Shah PB, Cockrill BA, Farber HW, Landzberg MJ, Mehra MR, Mullen MP, Opotowsky AR, Waxman AB, Lock JE, Marshall AC. Transcatheter Potts shunt creation in patients with severe pulmonary arterial hypertension: initial clinical experience. J Heart Lung Transplant. 2013 Apr; 32(4):381-7.
  48. Assenza GE, Graham DA, Landzberg MJ, Valente AM, Singh MN, Bashir A, Fernandes S, Mortele KJ, Ukomadu C, Volpe M, Wu F. MELD-XI score and cardiac mortality or transplantation in patients after Fontan surgery. Heart. 2013 Apr; 99(7):491-6.
  49. Fernandes SM, Pearson DD, Rzeszut A, Mitchell SJ, Landzberg MJ, Martin GR. Adult congenital heart disease incidence and consultation: a survey of general adult cardiologists. J Am Coll Cardiol. 2013 Mar 26; 61(12):1303-4.
  50. Aboulhosn JA, Lluri G, Gurvitz MZ, Khairy P, Mongeon FP, Kay J, Valente AM, Earing MG, Opotowsky AR, Lui G, Gersony DR, Cook S, Child J, Ting J, Webb G, Landzberg M, Broberg CS. Left and right ventricular diastolic function in adults with surgically repaired tetralogy of Fallot: a multi-institutional study. Can J Cardiol. 2013 Jul; 29(7):866-72.
  51. Egidy Assenza G, Cassater D, Landzberg M, Geva T, Schreier J, Graham D, Volpe M, Barker N, Economy K, Valente AM. The effects of pregnancy on right ventricular remodeling in women with repaired tetralogy of Fallot. Int J Cardiol. 2013 Oct 3; 168(3):1847-52.
  52. Learn CP, Holzer RJ, Daniels CJ, Torres AJ, Vincent JA, Moore JW, Armsby LB, Landzberg MJ, Bergersen L. Adverse events rates and risk factors in adults undergoing cardiac catheterization at pediatric hospitals--results from the C3PO. Catheter Cardiovasc Interv. 2013 May; 81(6):997-1005.
  53. Assenza GE, McElhinney DB, Valente AM, Pearson DD, Volpe M, Martucci G, Landzberg MJ, Lock JE. Transcatheter closure of post-myocardial infarction ventricular septal rupture. Circ Cardiovasc Interv. 2013 Feb; 6(1):59-67.
  54. Baraona F, Gurvitz M, Landzberg MJ, Opotowsky AR. Hospitalizations and mortality in the United States for adults with Down syndrome and congenital heart disease. Am J Cardiol. 2013 Apr 1; 111(7):1046-51.
  55. Kovacs AH, Landzberg MJ, Goodlin SJ. Advance care planning and end-of-life management of adult patients with congenital heart disease. World J Pediatr Congenit Heart Surg. 2013 Jan; 4(1):62-9.
  56. Caudry S, Landzberg M. Lateral window sinus elevation technique: managing challenges and complications. J Can Dent Assoc. 2013; 79:d101.
  57. Khairy P, Clair M, Fernandes SM, Blume ED, Powell AJ, Newburger JW, Landzberg MJ, Mayer JE. Cardiovascular outcomes after the arterial switch operation for D-transposition of the great arteries. Circulation. 2013 Jan 22; 127(3):331-9.
  58. Mongeon FP, Gurvitz MZ, Broberg CS, Aboulhosn J, Opotowsky AR, Kay JD, Valente AM, Earing MG, Lui GK, Fernandes SM, Gersony DR, Cook SC, Ting JG, Nickolaus MJ, Landzberg MJ, Khairy P. Aortic root dilatation in adults with surgically repaired tetralogy of fallot: a multicenter cross-sectional study. Circulation. 2013 Jan 15; 127(2):172-9.
  59. Landzberg MJ. Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: a need for further dialogue, development, and collaborative study. Circ Cardiovasc Interv. 2012 Dec; 5(6):744-5.
  60. Krieger EV, Clair M, Opotowsky AR, Landzberg MJ, Rhodes J, Powell AJ, Colan SD, Valente AM. Correlation of exercise response in repaired coarctation of the aorta to left ventricular mass and geometry. Am J Cardiol. 2013 Feb 1; 111(3):406-11.
  61. Opotowsky AR, Perlstein T, Landzberg MJ, Colan SD, O'Gara PT, Body SC, Ryan LF, Aranki S, Singh MN. A shifting approach to management of the thoracic aorta in bicuspid aortic valve. J Thorac Cardiovasc Surg. 2013 Aug; 146(2):339-46.
  62. Fernandes SM, Khairy P, Fishman L, Melvin P, O'Sullivan-Oliveira J, Sawicki GS, Ziniel S, Breitinger P, Williams R, Takahashi M, Landzberg MJ. Referral patterns and perceived barriers to adult congenital heart disease care: results of a survey of U.S. pediatric cardiologists. J Am Coll Cardiol. 2012 Dec 11; 60(23):2411-8.
  63. Egidy Assenza G, Valente AM, Geva T, Graham D, Pluchinotta FR, Romana Pluchinotta F, Sanders SP, Autore C, Volpe M, Landzberg MJ, Cecchin F. QRS duration and QRS fractionation on surface electrocardiogram are markers of right ventricular dysfunction and atrialization in patients with Ebstein anomaly. Eur Heart J. 2013 Jan; 34(3):191-200.
  64. Maron BA, Opotowsky AR, Landzberg MJ, Loscalzo J, Waxman AB, Leopold JA. Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study. Eur J Heart Fail. 2013 Mar; 15(3):277-83.
  65. Mousavi N, Shook DC, Kilcullen N, Aranki S, Kwong RY, Landzberg MJ, Blankstein R. Multimodality imaging of a Gerbode defect. Circulation. 2012 Jul 3; 126(1):e1-2.
  66. Krieger EV, Moko LE, Wu F, Landzberg MJ, Valente AM, Assenza GE, Ukomadu C, Opotowsky AR. Single ventricle anatomy is associated with increased frequency of nonalcoholic cirrhosis. Int J Cardiol. 2013 Sep 1; 167(5):1918-23.
  67. Valente AM, Gauvreau K, Assenza GE, Babu-Narayan SV, Evans SP, Gatzoulis M, Groenink M, Inuzuka R, Kilner PJ, Koyak Z, Landzberg MJ, Mulder B, Powell AJ, Wald R, Geva T. Rationale and design of an International Multicenter Registry of patients with repaired tetralogy of Fallot to define risk factors for late adverse outcomes: the INDICATOR cohort. Pediatr Cardiol. 2013 Jan; 34(1):95-104.
  68. Krieger EV, Valente AM, Landzberg MJ, Stout KK. Acute dyspnea in a young man with an old sternotomy. Congenit Heart Dis. 2012 Sep-Oct; 7(5):E73-7.
  69. Furlan AJ, Reisman M, Massaro J, Mauri L, Adams H, Albers GW, Felberg R, Herrmann H, Kar S, Landzberg M, Raizner A, Wechsler L. Closure or medical therapy for cryptogenic stroke with patent foramen ovale. N Engl J Med. 2012 Mar 15; 366(11):991-9.
  70. Martin GR, Mitchell S, Beekman RH, Feinstein JA, Jenkins KJ, Landzberg M, Webb G. The Adult Congenital and Pediatric Cardiology Section: increasing the opportunities for the congenital heart disease community within the American College of Cardiology. J Am Coll Cardiol. 2012 Jan 3; 59(1):84-7.
  71. Fernandes SM, Verstappen A, Ackerman K, Adams EE, Barton C, Breitinger P, Crumb S, Dummer K, Harada K, Khairy P, Landzberg MJ, Linstead-Goldsmith R, Meadows AK, Nieves JA, Saidi A, Takahashi M, Zhou J, Ziniel S, Williams R. Parental knowledge regarding lifelong congenital cardiac care. Pediatrics. 2011 Dec; 128(6):e1489-95.
  72. Lee MS, Pande RL, Rao B, Landzberg MJ, Kwong RY. Cerebral abscess due to persistent left superior vena cava draining into the left atrium. Circulation. 2011 Nov 22; 124(21):2362-4.
  73. Kim YY, Gauvreau K, Bacha EA, Landzberg MJ, Benavidez OJ. Resource use among adult congenital heart surgery admissions in pediatric hospitals: risk factors for high resource utilization and association with inpatient death. Circ Cardiovasc Qual Outcomes. 2011 Nov 1; 4(6):634-9.
  74. Opotowsky AR, Siddiqi OK, D'Souza B, Webb GD, Fernandes SM, Landzberg MJ. Maternal cardiovascular events during childbirth among women with congenital heart disease. Heart. 2012 Jan; 98(2):145-51.
  75. Bhatt AB, Landzberg MJ, Gerhard-Herman M, Rodriguez-Huertas E, Graham D, Valente AM. Pathophysiology of chronic venous insufficiency in adults with a Fontan circulation (a pre-defined substudy of the CALF investigation). Int J Cardiol. 2013 Apr 30; 165(1):41-5.
  76. Kim YY, Gauvreau K, Bacha EA, Landzberg MJ, Benavidez OJ. Risk factors for death after adult congenital heart surgery in pediatric hospitals. Circ Cardiovasc Qual Outcomes. 2011 Jul; 4(4):433-9.
  77. Arendt KW, Fernandes SM, Khairy P, Warnes CA, Rose CH, Landzberg MJ, Craigo PA, Hebl JR. A case series of the anesthetic management of parturients with surgically repaired tetralogy of Fallot. Anesth Analg. 2011 Aug; 113(2):307-17.
  78. Fernandes SM, Alexander ME, Graham DA, Khairy P, Clair M, Rodriguez E, Pearson DD, Landzberg MJ, Rhodes J. Exercise testing identifies patients at increased risk for morbidity and mortality following Fontan surgery. Congenit Heart Dis. 2011 Jul-Aug; 6(4):294-303.
  79. Krieger EV, Landzberg MJ, Economy KE, Webb GD, Opotowsky AR. Comparison of risk of hypertensive complications of pregnancy among women with versus without coarctation of the aorta. Am J Cardiol. 2011 May 15; 107(10):1529-34.
  80. Khairy P, Fernandes SM, Landzberg MJ. Pregnancy-related cardiac risk in women with congenital heart disease: is it over when it's over? Evid Based Med. 2011 Jun; 16(3):93-4.
  81. Landzberg MJ. Introduction: Adult congenital heart disease. Prog Cardiovasc Dis. 2011 Jan-Feb; 53(4):237-8.
  82. Meadows J, Landzberg MJ. Advances in transcatheter interventions in adults with congenital heart disease. Prog Cardiovasc Dis. 2011 Jan-Feb; 53(4):265-73.
  83. Opotowsky AR, Landzberg MJ. Bicuspid aortic valve morphology. J Am Coll Cardiol. 2010 Nov 9; 56(20):1680; author reply 1680-1.
  84. Furlan AJ, Reisman M, Massaro J, Mauri L, Adams H, Albers GW, Felberg R, Herrmann H, Kar S, Landzberg M, Raizner A, Wechsler L. Study design of the CLOSURE I Trial: a prospective, multicenter, randomized, controlled trial to evaluate the safety and efficacy of the STARFlex septal closure system versus best medical therapy in patients with stroke or transient ischemic attack due to presumed paradoxical embolism through a patent foramen ovale. Stroke. 2010 Dec; 41(12):2872-83.
  85. Khairy P, Aboulhosn J, Gurvitz MZ, Opotowsky AR, Mongeon FP, Kay J, Valente AM, Earing MG, Lui G, Gersony DR, Cook S, Ting JG, Nickolaus MJ, Webb G, Landzberg MJ, Broberg CS. Arrhythmia burden in adults with surgically repaired tetralogy of Fallot: a multi-institutional study. Circulation. 2010 Aug 31; 122(9):868-75.
  86. Tobler D, Fernandes SM, Wald RM, Landzberg M, Salehian O, Siu SC, Colman JM, Sermer M, Silversides CK. Pregnancy outcomes in women with transposition of the great arteries and arterial switch operation. Am J Cardiol. 2010 Aug 1; 106(3):417-20.
  87. Valente AM, Bhatt AB, Cook S, Earing MG, Gersony DR, Aboulhosn J, Opotowsky AR, Lui G, Gurvitz M, Graham D, Fernandes SM, Khairy P, Webb G, Gerhard-Herman M, Landzberg MJ. The CALF (Congenital Heart Disease in Adults Lower Extremity Systemic Venous Health in Fontan Patients) study. J Am Coll Cardiol. 2010 Jul 6; 56(2):144-50.
  88. Fernandes SM, Landzberg MJ. Pregnancy in patients with tetralogy of fallot: invited commentary. World J Pediatr Congenit Heart Surg. 2010 Jul; 1(2):175-6.
  89. Stewart BA, Fernandes S, Rodriguez-Huertas E, Landzberg M. A preliminary look at duplicate testing associated with lack of electronic health record interoperability for transferred patients. J Am Med Inform Assoc. 2010 May-Jun; 17(3):341-4.
  90. Valente AM, Lock JE, Gauvreau K, Rodriguez-Huertas E, Joyce C, Armsby L, Bacha EA, Landzberg MJ. Predictors of long-term adverse outcomes in patients with congenital coronary artery fistulae. Circ Cardiovasc Interv. 2010 Apr; 3(2):134-9.
  91. Fernandes SM, Arendt KW, Landzberg MJ, Economy KE, Khairy P. Pregnant women with congenital heart disease: cardiac, anesthetic and obstetrical implications. Expert Rev Cardiovasc Ther. 2010 Mar; 8(3):439-48.
  92. O'Donnell CP, Landzberg MJ, Mullen MP. Lung abscess in adults with tetralogy of fallot and pulmonary atresia. Cardiol Young. 2010 Feb; 20(1):91-3.
  93. Fernandes SM, McElhinney DB, Khairy P, Graham DA, Landzberg MJ, Rhodes J. Serial cardiopulmonary exercise testing in patients with previous Fontan surgery. Pediatr Cardiol. 2010 Feb; 31(2):175-80.
  94. Landzberg MJ, Cecchin F. Atrial arrhythmias: a "call to arms" for congenital heart disease caregivers. Circulation. 2009 Oct 27; 120(17):1649-50.
  95. Berger RM, Beghetti M, Galiè N, Gatzoulis MA, Granton J, Lauer A, Chiossi E, Landzberg M. Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger's syndrome: a subgroup analysis. Int J Cardiol. 2010 Oct 29; 144(3):373-8.
  96. Ouyang DW, Khairy P, Fernandes SM, Landzberg MJ, Economy KE. Obstetric outcomes in pregnant women with congenital heart disease. Int J Cardiol. 2010 Oct 8; 144(2):195-9.
  97. Opotowsky AR, Landzberg MJ, Kimmel SE, Webb GD. Percutaneous closure of patent foramen ovale and atrial septal defect in adults: the impact of clinical variables and hospital procedure volume on in-hospital adverse events. Am Heart J. 2009 May; 157(5):867-74.
  98. Martucci G, Landzberg M. Not just big kids: closing atrial septal defects in adults older than 60 years. Circ Cardiovasc Interv. 2009 Apr; 2(2):83-4.
  99. Lok SI, Winkens B, Dimopoulos K, Fernandes SM, Gatzoulis MA, Landzberg MJ, Mulder BJ. Recurrence of cerebrovascular events in young adults with a secundum atrial septal defect. Int J Cardiol. 2010 Jun 25; 142(1):44-9.
  100. Warnes CA, Williams RG, Bashore TM, Child JS, Connolly HM, Dearani JA, del Nido P, Fasules JW, Graham TP, Hijazi ZM, Hunt SA, King ME, Landzberg MJ, Miner PD, Radford MJ, Walsh EP, Webb GD, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Halperin JL, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura RA, Page RL, Riegel B, Tarkington LG, Yancy CW. ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Develop Guidelines on the Management of Adults With Congenital Heart Disease). Developed in Collaboration With the American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2008 Dec 2; 52(23):e143-263.
  101. Warnes CA, Williams RG, Bashore TM, Child JS, Connolly HM, Dearani JA, Del Nido P, Fasules JW, Graham TP, Hijazi ZM, Hunt SA, King ME, Landzberg MJ, Miner PD, Radford MJ, Walsh EP, Webb GD. ACC/AHA 2008 Guidelines for the Management of Adults with Congenital Heart Disease: Executive Summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelines for the management of adults with congenital heart disease). Circulation. 2008 Dec 2; 118(23):2395-451.
  102. Warnes CA, Williams RG, Bashore TM, Child JS, Connolly HM, Dearani JA, del Nido P, Fasules JW, Graham TP, Hijazi ZM, Hunt SA, King ME, Landzberg MJ, Miner PD, Radford MJ, Walsh EP, Webb GD. ACC/AHA 2008 Guidelines for the Management of Adults with Congenital Heart Disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelines on the management of adults with congenital heart disease). Circulation. 2008 Dec 2; 118(23):e714-833.
  103. Khairy P, Harris L, Landzberg MJ, Fernandes SM, Barlow A, Mercier LA, Viswanathan S, Chetaille P, Gordon E, Dore A, Cecchin F. Sudden death and defibrillators in transposition of the great arteries with intra-atrial baffles: a multicenter study. Circ Arrhythm Electrophysiol. 2008 Oct; 1(4):250-7.
  104. Khairy P, Hosn JA, Broberg C, Cook S, Earing M, Gersony D, Kay J, Landzberg MJ, Nickolaus MJ, Opotowsky S, Valente AM, Warnes C, Webb G, Gurvitz MZ. Multicenter research in adult congenital heart disease. Int J Cardiol. 2008 Sep 26; 129(2):155-9.
  105. Khairy P, Landzberg MJ. Adult congenital heart disease: toward prospective risk assessment of a multisystemic condition. Circulation. 2008 May 6; 117(18):2311-2.
  106. Opotowsky AR, Landzberg MJ, Kimmel SE, Webb GD. Trends in the use of percutaneous closure of patent foramen ovale and atrial septal defect in adults, 1998-2004. JAMA. 2008 Feb 6; 299(5):521-2.
  107. Khairy P, Harris L, Landzberg MJ, Viswanathan S, Barlow A, Gatzoulis MA, Fernandes SM, Beauchesne L, Therrien J, Chetaille P, Gordon E, Vonder Muhll I, Cecchin F. Implantable cardioverter-defibrillators in tetralogy of Fallot. Circulation. 2008 Jan 22; 117(3):363-70.
  108. Khairy P, Fernandes SM, Mayer JE, Triedman JK, Walsh EP, Lock JE, Landzberg MJ. Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery. Circulation. 2008 Jan 1; 117(1):85-92.
  109. Lim DS, Forbes TJ, Rothman A, Lock JE, Landzberg MJ. Transcatheter closure of high-risk muscular ventricular septal defects with the CardioSEAL occluder: initial report from the CardioSEAL VSD registry. Catheter Cardiovasc Interv. 2007 Nov 1; 70(5):740-4.
  110. Gatzoulis MA, Beghetti M, Galiè N, Granton J, Berger RM, Lauer A, Chiossi E, Landzberg M. Longer-term bosentan therapy improves functional capacity in Eisenmenger syndrome: results of the BREATHE-5 open-label extension study. Int J Cardiol. 2008 Jun 23; 127(1):27-32.
  111. Memtsoudis SG, Lekowski RW, Rosenberger P, Khalpey Z, FitzGerald DJ, Claypoole V, Courtney KD, Landzberg MJ, Bunn HF, Shekar PS. Pulmonary thrombectomy in a patient with hemoglobin Nottingham. Perfusion. 2007 Jul; 22(4):299-301.
  112. Inglessis I, Landzberg MJ. Interventional catheterization in adult congenital heart disease. Circulation. 2007 Mar 27; 115(12):1622-33.
  113. Landzberg MJ. Congenital heart disease associated pulmonary arterial hypertension. Clin Chest Med. 2007 Mar; 28(1):243-53, x.
  114. Qureshi AM, McElhinney DB, Lock JE, Landzberg MJ, Lang P, Marshall AC. Acute and intermediate outcomes, and evaluation of injury to the aortic wall, as based on 15 years experience of implanting stents to treat aortic coarctation. Cardiol Young. 2007 Jun; 17(3):307-18.
  115. Fortescue EB, Shin AY, Greenes DS, Mannix RC, Agarwal S, Feldman BJ, Shah MI, Rifai N, Landzberg MJ, Newburger JW, Almond CS. Cardiac troponin increases among runners in the Boston Marathon. Ann Emerg Med. 2007 Feb; 49(2):137-43, 143.e1.
  116. Knauth AL, Gauvreau K, Powell AJ, Landzberg MJ, Walsh EP, Lock JE, del Nido PJ, Geva T. Ventricular size and function assessed by cardiac MRI predict major adverse clinical outcomes late after tetralogy of Fallot repair. Heart. 2008 Feb; 94(2):211-6.
  117. Canobbio MM, Morris CD, Graham TP, Landzberg MJ. Pregnancy outcomes after atrial repair for transposition of the great arteries. Am J Cardiol. 2006 Sep 1; 98(5):668-72.
  118. Eckart RE, Hruczkowski TW, Landzberg MJ, Ames A, Epstein LM. Pulmonary arterial embolization of pacemaker lead electrode tip. Pacing Clin Electrophysiol. 2006 Jul; 29(7):784-7.
  119. Galiè N, Beghetti M, Gatzoulis MA, Granton J, Berger RM, Lauer A, Chiossi E, Landzberg M. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation. 2006 Jul 4; 114(1):48-54.
  120. Landzberg MJ, Ungerleider R. Pediatric cardiology and adult congenital heart disease. J Am Coll Cardiol. 2006 Jun 6; 47(11 Suppl):D33-6.
  121. Khairy P, Landzberg MJ, Gatzoulis MA, Mercier LA, Fernandes SM, Côté JM, Lavoie JP, Fournier A, Guerra PG, Frogoudaki A, Walsh EP, Dore A. Transvenous pacing leads and systemic thromboemboli in patients with intracardiac shunts: a multicenter study. Circulation. 2006 May 23; 113(20):2391-7.
  122. Khairy P, Ouyang DW, Fernandes SM, Lee-Parritz A, Economy KE, Landzberg MJ. Pregnancy outcomes in women with congenital heart disease. Circulation. 2006 Jan 31; 113(4):517-24.
  123. Williams RG, Pearson GD, Barst RJ, Child JS, del Nido P, Gersony WM, Kuehl KS, Landzberg MJ, Myerson M, Neish SR, Sahn DJ, Verstappen A, Warnes CA, Webb CL. Report of the National Heart, Lung, and Blood Institute Working Group on research in adult congenital heart disease. J Am Coll Cardiol. 2006 Feb 21; 47(4):701-7.
  124. Spray TL, Landzberg M. Pediatric cardiology and congenital heart disease. J Am Coll Cardiol. 2005 Jun 7; 45(11 Suppl B):9B-11B.
  125. Paul S, Mihaljevic T, Leacche M, Landzberg M, Ho CY, Blake GJ, Byrne JG. Postinfarction ventricular septal defect with pseudoaneurysm repair after failed percutaneous closure. Ann Thorac Surg. 2005 Feb; 79(2):701-3.
  126. Fernandes SM, Landzberg MJ. Transitioning the young adult with congenital heart disease for life-long medical care. Pediatr Clin North Am. 2004 Dec; 51(6):1739-48, xi.
  127. Landzberg MJ, Brass L, Furlan A, Hellenbrand W, Hermann H, Kramer P, Palacios IF, Reisman M, Sommer R, Thomas C, Wechsler L. Transcatheter intracardiac device implantation for atrial level defects and thrombosis: a call for randomized, controlled data. J Am Coll Cardiol. 2004 Oct 19; 44(8):1713-4; author reply 1714-6.
  128. Benisty JI, McLaughlin VV, Landzberg MJ, Rich JD, Newburger JW, Rich S, Folkman J. Elevated basic fibroblast growth factor levels in patients with pulmonary arterial hypertension. Chest. 2004 Oct; 126(4):1255-61.
  129. Knauth AL, Lock JE, Perry SB, McElhinney DB, Gauvreau K, Landzberg MJ, Rome JJ, Hellenbrand WE, Ruiz CE, Jenkins KJ. Transcatheter device closure of congenital and postoperative residual ventricular septal defects. Circulation. 2004 Aug 3; 110(5):501-7.
  130. Khairy P, Landzberg MJ, Lambert J, O'Donnell CP. Long-term outcomes after the atrial switch for surgical correction of transposition: a meta-analysis comparing the Mustard and Senning procedures. Cardiol Young. 2004 Jun; 14(3):284-92.
  131. Khairy P, Landzberg MJ, Gatzoulis MA, Lucron H, Lambert J, Marçon F, Alexander ME, Walsh EP. Value of programmed ventricular stimulation after tetralogy of fallot repair: a multicenter study. Circulation. 2004 Apr 27; 109(16):1994-2000.
  132. Landzberg MJ, Khairy P. Indications for the closure of patent foramen ovale. Heart. 2004 Feb; 90(2):219-24.
  133. Khairy P, O'Donnell CP, Landzberg MJ. Transcatheter closure versus medical therapy of patent foramen ovale and presumed paradoxical thromboemboli: a systematic review. Ann Intern Med. 2003 Nov 4; 139(9):753-60.
  134. Fernandes SM, Newburger JW, Lang P, Pearson DD, Feinstein JA, Gauvreau K, Landzberg MJ. Usefulness of epoprostenol therapy in the severely ill adolescent/adult with Eisenmenger physiology. Am J Cardiol. 2003 Mar 1; 91(5):632-5.
  135. Bromberg JI, Beasley PJ, D'Angelo EJ, Landzberg M, DeMaso DR. Depression and anxiety in adults with congenital heart disease: a pilot study. Heart Lung. 2003 Mar-Apr; 32(2):105-10.
  136. Yeon HB, Ramappa A, Landzberg MJ, Thornhill TS. Paradoxic cerebral embolism after cemented knee arthroplasty: a report of 2 cases and prophylactic option for subsequent arthroplasty. J Arthroplasty. 2003 Jan; 18(1):113-20.
  137. Geva T, Greil GF, Marshall AC, Landzberg M, Powell AJ. Gadolinium-enhanced 3-dimensional magnetic resonance angiography of pulmonary blood supply in patients with complex pulmonary stenosis or atresia: comparison with x-ray angiography. Circulation. 2002 Jul 23; 106(4):473-8.
  138. Rubin LJ, Badesch DB, Barst RJ, Galie N, Black CM, Keogh A, Pulido T, Frost A, Roux S, Leconte I, Landzberg M, Simonneau G. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med. 2002 Mar 21; 346(12):896-903.
  139. Preston IR, Klinger JR, Landzberg MJ, Houtchens J, Nelson D, Hill NS. Vasoresponsiveness of sarcoidosis-associated pulmonary hypertension. Chest. 2001 Sep; 120(3):866-72.
  140. Kwok OH, Landzberg MJ, Kinlay S, Marcus KC, Rogers C. Percutaneous coronary intervention and subsequent endovascular beta-radiation brachytherapy in a 14-year-old with repaired anomalous left coronary artery from pulmonary artery. J Invasive Cardiol. 2001 Jun; 13(6):494-500.
  141. Landzberg MJ. Catheterization of the adult with congenital heart disease (ACHD): beyond "shooting the coronaries". J Interv Cardiol. 2001 Jun; 14(3):329-37.
  142. Delacretaz E, Ganz LI, Soejima K, Friedman PL, Walsh EP, Triedman JK, Sloss LJ, Landzberg MJ, Stevenson WG. Multi atrial maco-re-entry circuits in adults with repaired congenital heart disease: entrainment mapping combined with three-dimensional electroanatomic mapping. J Am Coll Cardiol. 2001 May; 37(6):1665-76.
  143. Landzberg MJ. Closure of atrial septal defects in adult patients: justification of the "tipping point". J Interv Cardiol. 2001 Apr; 14(2):267-9.
  144. Landzberg MJ, Murphy DJ, Davidson WR, Jarcho JA, Krumholz HM, Mayer JE, Mee RB, Sahn DJ, Van Hare GF, Webb GD, Williams RG. Task force 4: organization of delivery systems for adults with congenital heart disease. J Am Coll Cardiol. 2001 Apr; 37(5):1187-93.
  145. Feinstein JA, Goldhaber SZ, Lock JE, Ferndandes SM, Landzberg MJ. Balloon pulmonary angioplasty for treatment of chronic thromboembolic pulmonary hypertension. Circulation. 2001 Jan 2; 103(1):10-3.
  146. Powell AJ, Chung T, Landzberg MJ, Geva T. Accuracy of MRI evaluation of pulmonary blood supply in patients with complex pulmonary stenosis or atresia. Int J Card Imaging. 2000 Jun; 16(3):169-74.
  147. Hung J, Landzberg MJ, Jenkins KJ, King ME, Lock JE, Palacios IF, Lang P. Closure of patent foramen ovale for paradoxical emboli: intermediate-term risk of recurrent neurological events following transcatheter device placement. J Am Coll Cardiol. 2000 Apr; 35(5):1311-6.
  148. Robinson JN, Banerjee R, Landzberg MJ, Thiet MP. Inhaled nitric oxide therapy in pregnancy complicated by pulmonary hypertension. Am J Obstet Gynecol. 1999 Apr; 180(4):1045-6.
  149. Be'eri E, Maier SE, Landzberg MJ, Chung T, Geva T. In vivo evaluation of Fontan pathway flow dynamics by multidimensional phase-velocity magnetic resonance imaging. Circulation. 1998 Dec 22-29; 98(25):2873-82.
  150. Landzberg MJ, Lock JE. Transcatheter management of ventricular septal rupture after myocardial infarction. Semin Thorac Cardiovasc Surg. 1998 Apr; 10(2):128-32.
  151. Kreutzer J, Landzberg MJ, Preminger TJ, Mandell VS, Treves ST, Reid LM, Lock JE. Isolated peripheral pulmonary artery stenoses in the adult. Circulation. 1996 Apr 1; 93(7):1417-23.
  152. Burke RP, Horvath K, Landzberg M, Hyde P, Collins JJ, Cohn LH. Long-term follow-up after surgical repair of ostium primum atrial septal defects in adults. J Am Coll Cardiol. 1996 Mar 1; 27(3):696-9.
  153. Cooper CJ, Landzberg MJ, Anderson TJ, Charbonneau F, Creager MA, Ganz P, Selwyn AP. Role of nitric oxide in the local regulation of pulmonary vascular resistance in humans. Circulation. 1996 Jan 15; 93(2):266-71.
  154. Landzberg MJ, Sloss LJ, Faherty CE, Morrison BJ, Bittl JA, Bridges ND, Casale PN, Keane JF, Lock JE. Orthodeoxia-platypnea due to intracardiac shunting--relief with transcatheter double umbrella closure. Cathet Cardiovasc Diagn. 1995 Nov; 36(3):247-50.
  155. Tanel RE, Wernovsky G, Landzberg MJ, Perry SB, Burke RP. Coronary artery abnormalities detected at cardiac catheterization following the arterial switch operation for transposition of the great arteries. Am J Cardiol. 1995 Jul 15; 76(3):153-7.
  156. Adatia I, Perry S, Landzberg M, Moore P, Thompson JE, Wessel DL. Inhaled nitric oxide and hemodynamic evaluation of patients with pulmonary hypertension before transplantation. J Am Coll Cardiol. 1995 Jun; 25(7):1656-64.
  157. Rosenfeld HM, Landzberg MJ, Perry SB, Colan SD, Keane JF, Lock JE. Balloon aortic valvuloplasty in the young adult with congenital aortic stenosis. Am J Cardiol. 1994 Jun 1; 73(15):1112-7.
  158. Landzberg MJ, Lock JE. Interventional catheter procedures used in congenital heart disease. Cardiol Clin. 1993 Nov; 11(4):569-87.
  159. Adatia I, Thompson J, Landzberg M, Wessel DL. Inhaled nitric oxide in chronic obstructive lung disease. Lancet. 1993 Jan 30; 341(8840):307-8.
  160. Landzberg MJ, Lock JE. Transcatheter closure of cardiac defects. Adv Pediatr. 1993; 40:247-71.
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