Summary
This study aims to learn more about blood management in children undergoing heart surgery, such as the right amounts, and the best blood products, to administer. It also aims to develop a mathematical model that may help researchers better predict and treat patients who need blood transfusions during heart surgery.
Conditions
Heart Surgery, Blood Transfusion, Hemolysis
Recruitment Status
NOT_YET_RECRUITING
Eligibility Criteria
Inclusion Criteria:
* pediatric patients under 18 years of age undergoing cardiac surgery with clear prime on cardio-pulmonary bypass (CPB) at Boston Children's Hospital (BCH).
Exclusion Criteria:
* patients with known hemolytic disorders, patients on nitric oxide preoperatively, and patients found to have abnormal coagulation on routine preoperative assessment. Patients receiving heparin, American Society of Anesthesia (ASA) status, apixaban, warfarin, or bivalirudin held appropriately (i.e. for elective surgery) will not be excluded
Intervention
Intervention Type
Intervention Name
OTHER
blood sampling
Gender
ALL
Min Age
0 Years
Max Age
17 Years
Download Date
2025-07-16
Principal Investigator
This field has been modified from ClinicalTrials.gov to show a contact specific to Boston Children's.
Primary Contact Information
jocelyn.booth@childrens.harvard.edu
Rachel Bernier, MPH
rachel.bernier@childrens.harvard.edu
This field has been modified from ClinicalTrials.gov to show a contact specific to Boston Children's.
For more information on this trial, visit clinicaltrials.gov.
Contact
For more information and to contact the study team: