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Brian K. Walsh, RRT-NPS

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Department of Anesthesiology, Perioperative and Pain Medicine Research
Research Focus Area:
Respiratory Care and EducationMechanical VentilationData analyticsAcute Respiratory Distress SyndromeAsthma

Research Overview

His clinical and laboratory efforts have directed the development of innovative technologies in the arena of respiratory support, including high frequency oscillatory ventilation, non-invasive monitoring including oxygen indices to determine cardiac output and oxygen delivery, tidal volume, and electrical impedance tomography to monitor regional lung mechanics to guide lung protective ventilation. Recently Mr. Walsh has turned his attention to mechanical ventilation and cardiopulmonary data analytics. Computer aided mechanical ventilation (CAMV) system of care that continuously monitors the ventilator and the physiologic effects of therapy. This system of care provides real-time visualization of MV and physiologic parameters within an infographic. CAMV will be the first to utilize both ventilator mechanics and physiologic monitoring of continuous data within one system to provide seamless tracking through our established Tracking, Trajectory, and Triggering (T3) system. Through these measurements and assigned targets, classification of ventilation and oxygenation can be summarized. By providing a continuous monitoring system, clinicians will be able to determine status changes quicker and hopefully avoid the complication associated with MV. This system will further standardize care, inform decisions, and objectively measure the compliance of goal directed therapy. CAMV has the potential to improve safety, quality and therefore outcomes of the critically ill patient who requires respiratory support. Mr. Walsh assists with the Respiratory Care educational content of OPENPediatrics and is a the editor of Neonatal and Pediatric Respiratory Care. He also serves the American Association for Respiratory Care at their Vice President.


Publications powered by Harvard Catalyst Profiles
  1. Walsh BK, Smallwood CD, Arnold JH. The Quality of Quality Metrics-Reply. Respir Care. 2017 Feb; 62(2):254-255.
  2. Smallwood CD, Kheir JN, Walsh BK, Mehta NM. Accuracy of Oxygen Consumption and Carbon Dioxide Elimination Measurements in 2 Breath-by-Breath Devices. Respir Care. 2017 Jan 17.
  3. Walsh BK, Smallwood C, Rettig J, Kacmarek R, Thompson J, Arnold JH. Daily Goals Formulation and Enhanced Visualization of Mechanical Ventilation Variance Improves Mechanical Ventilation Score. Respir Care. 2017 Jan 10.
  4. Walsh BK. Is Anything Absolute? Respir Care. 2016 Dec; 61(12):1711.
  5. Walsh BK, Smallwood CD. Electrical Impedance Tomography During Mechanical Ventilation. Respir Care. 2016 Oct; 61(10):1417-24.
  6. Walsh BK. Next Logical Step. Respir Care. 2016 Sep; 61(9):1277-8.
  7. Walsh BK, Smallwood CD, Rettig JS, Thompson JE, Kacmarek RM, Arnold JH. Categorization in Mechanically Ventilated Pediatric Subjects: A Proposed Method to Improve Quality. Respir Care. 2016 Sep; 61(9):1168-78.
  8. Walsh BK, Betit P, Fink JB, Pereira LM, Arnold J. Characterization of Ribavirin Aerosol With Small Particle Aerosol Generator and Vibrating Mesh Micropump Aerosol Technologies. Respir Care. 2016 May; 61(5):577-85.
  9. Rettig JS, Smallwood CD, Walsh BK, Rimensberger PC, Bachman TE, Bollen CW, Duval EL, Gebistorf F, Markhorst DG, Tinnevelt M, Todd M, Zurakowski D, Arnold JH. High-Frequency Oscillatory Ventilation in Pediatric Acute Lung Injury: A Multicenter International Experience. Crit Care Med. 2015 Dec; 43(12):2660-7.
  10. Walsh BK, Davis MD, Hunt JF, Kheir JN, Smallwood CD, Arnold JH. The effects of lung recruitment maneuvers on exhaled breath condensate pH. J Breath Res. 2015 Sep; 9(3):036009.
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  12. Walsh BK, Rettig JS. Implementation of an inhaled nitric oxide protocol: a paradox or the perfect pair? Respir Care. 2015 May; 60(5):760-1.
  13. Smallwood CD, Walsh BK, Bechard LJ, Mehta NM. Carbon dioxide elimination and oxygen consumption in mechanically ventilated children. Respir Care. 2015 May; 60(5):718-23.
  14. Kaufman DA, Zanelli SA, Gurka MJ, Davis M, Richards CP, Walsh BK. Time outside targeted oxygen saturation range and retinopathy of prematurity. Early Hum Dev. 2014 Sep; 90 Suppl 2:S35-40.
  15. Sheeran PW, Walsh BK, Finley AM, Martin AK, Brenski AC. Management of difficult airway patients and the use of a difficult airway registry at a tertiary care pediatric hospital. Paediatr Anaesth. 2014 Aug; 24(8):819-24.
  16. Davis MD, Walsh BK, Sittig SE, Restrepo RD. AARC clinical practice guideline: blood gas analysis and hemoximetry: 2013. Respir Care. 2013 Oct; 58(10):1694-703.
  17. Walsh BK, Daigle B, DiBlasi RM, Restrepo RD. AARC Clinical Practice Guideline. Surfactant replacement therapy: 2013. Respir Care. 2013 Feb; 58(2):367-75.
  18. Davis MD, Walsh BK, Dwyer ST, Combs C, Vehse N, Paget-Brown A, Pajewski T, Hunt JF. Safety of an alkalinizing buffer designed for inhaled medications in humans. Respir Care. 2013 Jul; 58(7):1226-32.
  19. Kheir JN, Walsh BK, Smallwood CD, Rettig JS, Thompson JE, Gómez-Laberge C, Wolf GK, Arnold JH. Comparison of 2 lung recruitment strategies in children with acute lung injury. Respir Care. 2013 Aug; 58(8):1280-90.
  20. Walsh BK, Green M. Inhaled anesthetic for life-threatening bronchospasm: is it ready for prime time? Respir Care. 2012 Nov; 57(11):1982-3.
  21. Wolf GK, Gómez-Laberge C, Kheir JN, Zurakowski D, Walsh BK, Adler A, Arnold JH. Reversal of dependent lung collapse predicts response to lung recruitment in children with early acute lung injury. Pediatr Crit Care Med. 2012 Sep; 13(5):509-15.
  22. Kheir JN, Scharp LA, Borden MA, Swanson EJ, Loxley A, Reese JH, Black KJ, Velazquez LA, Thomson LM, Walsh BK, Mullen KE, Graham DA, Lawlor MW, Brugnara C, Bell DC, McGowan FX. Oxygen gas-filled microparticles provide intravenous oxygen delivery. Sci Transl Med. 2012 Jun 27; 4(140):140ra88.
  23. Restrepo RD, Walsh BK. Humidification during invasive and noninvasive mechanical ventilation: 2012. Respir Care. 2012 May; 57(5):782-8.
  24. Wolf GK, Walsh BK, Green ML, Arnold JH. Electrical activity of the diaphragm during extubation readiness testing in critically ill children. Pediatr Crit Care Med. 2011 Nov; 12(6):e220-4.
  25. Ferguson LP, Walsh BK, Munhall D, Arnold JH. A spontaneous breathing trial with pressure support overestimates readiness for extubation in children. Pediatr Crit Care Med. 2011 Nov; 12(6):e330-5.
  26. Walsh BK, Hood K, Merritt G. Pediatric airway maintenance and clearance in the acute care setting: how to stay out of trouble. Respir Care. 2011 Sep; 56(9):1424-40; discussion 1440-4.
  27. Steil GM, Eckstein OS, Caplow J, Agus MS, Walsh BK, Wong J. Non-invasive cardiac output and oxygen delivery measurement in an infant with critical anemia. J Clin Monit Comput. 2011 Apr; 25(2):113-9.
  28. Walsh BK, Gentile MA, Grenier BM. Orienting new respiratory therapists into the neonatal/pediatric environment: a survey of educators and managers. Respir Care. 2011 Aug; 56(8):1122-9.
  29. Green ML, Walsh BK, Wolf GK, Arnold JH. Electrocardiographic guidance for the placement of gastric feeding tubes: a pediatric case series. Respir Care. 2011 Apr; 56(4):467-71.
  30. Walsh BK, Crotwell DN, Restrepo RD. Capnography/Capnometry during mechanical ventilation: 2011. Respir Care. 2011 Apr; 56(4):503-9.
  31. Walsh BK, Craig N, Betit P, Thompson JE, Arnold JH. Respiratory distress associated with inadequate mechanical ventilator flow response in a neonate with congenital diaphragmatic hernia. Respir Care. 2010 Mar; 55(3):342-5.
  32. Walsh BK, Brooks TM, Grenier BM. Oxygen therapy in the neonatal care environment. Respir Care. 2009 Sep; 54(9):1193-202.
  33. Walsh BK, Mackey DJ, Pajewski T, Yu Y, Gaston BM, Hunt JF. Exhaled-breath condensate pH can be safely and continuously monitored in mechanically ventilated patients. Respir Care. 2006 Oct; 51(10):1125-31.
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