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Kevin Daly, MD

Kevin Daly MD
Research Center:
Transplant Research Program
Cardiology Research
Hospital Title:
Academic Title:
Instructor, Harvard Medical School
Research Focus Area:
Heart transplantationTransplant rejection

Research Overview

Dr. Daly's research is largely focused on novel, noninvasive techniques for the diagnosis and monitoring of cardiac allograft vasculopathy (CAV), including the development of serum biomarkers and novel imaging technologies.

Currently, he is studying the underpinnings of chronic allograft rejection—the major cause of mortality following pediatric heart transplant. Through his research, Dr. Daly aims to determine if endothelial injury and repair responses can be monitored in recipients of cardiac transplantation, and to establish if patterns of these biomarkers predict, or are associated with, the development of chronic allograft rejection. In addition, Dr. Daly's research aims to establish whether molecular imaging studies of myocardial blood flow and endothelial cell activation are associated with early CAV/chronic rejection.

About Kevin Daly

Dr. Daly received his MD from Columbia University College of Physicians & Surgeons. He completed his internship and residency at the Children’s Hospital at Montefiore (Albert Einstein College of Medicine) and his fellowship at Boston Children's Hospital.


Publications powered by Harvard Catalyst Profiles
  1. Mills KI, Vincent JA, Zuckerman WA, Hoffman TM, Canter CE, Marshall AC, Blume ED, Bergersen L, Daly KP. Is Endomyocardial Biopsy a Safe and Useful Procedure in Children with Suspected Cardiomyopathy? Pediatr Cardiol. 2016 Oct; 37(7):1200-10.
  2. Daly KP. Finding the correct role for heart transplant in the treatment of hypoplastic left heart syndrome. J Heart Lung Transplant. 2016 Mar; 35(3):299-300.
  3. Kamin DS, Freiberger D, Daly KP, Oliva M, Helfand L, Haynes K, Harrison CH, Kim HB. What Is the Role of Developmental Disability in Patient Selection for Pediatric Solid Organ Transplantation? Am J Transplant. 2016 Mar; 16(3):767-72.
  4. Daly KP, Dearling JL, Seto T, Dunning P, Fahey F, Packard AB, Briscoe DM. Use of [18F]FDG Positron Emission Tomography to Monitor the Development of Cardiac Allograft Rejection. Transplantation. 2015 Sep; 99(9):e132-9.
  5. Starling RC, Stehlik J, Baran DA, Armstrong B, Stone JR, Ikle D, Morrison Y, Bridges ND, Putheti P, Strom TB, Bhasin M, Guleria I, Chandraker A, Sayegh M, Daly KP, Briscoe DM, Heeger PS. Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study. Am J Transplant. 2016 Jan; 16(1):121-36.
  6. Jacobs JP, Quintessenza JA, Karl TR, Asante-Korang A, Everett AD, Collins SB, Ramirez-Correa GA, Burns KM, Cohen M, Colan SD, Costello JM, Daly KP, Franklin RC, Fraser CD, Hill KD, Huhta JC, Kaushal S, Law YM, Lipshultz SE, Murphy AM, Pasquali SK, Payne MR, Rossano J, Shirali G, Ware SM, Xu M, Jacobs ML. Summary of the 2015 International Paediatric Heart Failure Summit of Johns Hopkins All Children's Heart Institute. Cardiol Young. 2015 Aug; 25 Suppl 2:8-30.
  7. Daly KP. Emerging science in paediatric heart transplantation: donor allocation, biomarkers, and the quest for evidence-based medicine. Cardiol Young. 2015 Aug; 25 Suppl 2:117-23.
  8. Bruneau S, Wedel J, Fakhouri F, Nakayama H, Boneschansker L, Irimia D, Daly KP, Briscoe DM. Translational implications of endothelial cell dysfunction in association with chronic allograft rejection. Pediatr Nephrol. 2016 Jan; 31(1):41-51.
  9. Daly KP. Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection? Ann Transl Med. 2015 Mar; 3(4):47.
  10. Sivananthan G, MacArthur DH, Daly KP, Allen DW, Hakham S, Halin NJ. Safety and efficacy of radiofrequency wire recanalization of chronic central venous occlusions. J Vasc Access. 2015 Jul-Aug; 16(4):309-14.
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  12. Daly KP, Chandler SF, Almond CS, Singh TP, Mah H, Milford E, Matte GS, Bastardi HJ, Mayer JE, Fynn-Thompson F, Blume ED. Antibody depletion for the treatment of crossmatch-positive pediatric heart transplant recipients. Pediatr Transplant. 2013 Nov; 17(7):661-9.
  13. Rhodes J, Ubeda-Tikkanen A, Clair M, Fernandes SM, Graham DA, Milliren CE, Daly KP, Mullen MP, Landzberg MJ. Effect of inhaled iloprost on the exercise function of Fontan patients: a demonstration of concept. Int J Cardiol. 2013 Oct 3; 168(3):2435-40.
  14. Daly KP, Seifert ME, Chandraker A, Zurakowski D, Nohria A, Givertz MM, Karumanchi SA, Briscoe DM. VEGF-C, VEGF-A and related angiogenesis factors as biomarkers of allograft vasculopathy in cardiac transplant recipients. J Heart Lung Transplant. 2013 Jan; 32(1):120-8.
  15. Bruneau S, Woda CB, Daly KP, Boneschansker L, Jain NG, Kochupurakkal N, Contreras AG, Seto T, Briscoe DM. Key Features of the Intragraft Microenvironment that Determine Long-Term Survival Following Transplantation. Front Immunol. 2012; 3:54.
  16. Daly KP, Marshall AC, Vincent JA, Zuckerman WA, Hoffman TM, Canter CE, Blume ED, Bergersen L. Endomyocardial biopsy and selective coronary angiography are low-risk procedures in pediatric heart transplant recipients: results of a multicenter experience. J Heart Lung Transplant. 2012 Apr; 31(4):398-409.
  17. Daly KP, Chakravarti SB, Tresler M, Naftel DC, Blume ED, Dipchand AI, Almond CS. Sudden death after pediatric heart transplantation: analysis of data from the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 2011 Dec; 30(12):1395-402.
  18. Daly KP, Colan SD, Blume ED, Margossian R, Gauvreau K, Duncan C, Lehmann LE, Chen MH. Changes in echocardiographic measures of systolic and diastolic function in children 1 year after hematopoietic SCT. Bone Marrow Transplant. 2011 Dec; 46(12):1532-9.
  19. Daly K, Nandula SV, Murty VV, Nichols G. Variant translocation with a deletion of derivative (9q) in a case of Philadelphia chromosome positive (Ph +) essential thrombocythemia (ET), a variant of chronic myelogenous leukemia (CML) with a poor prognosis. Leuk Lymphoma. 2005 Dec; 46(12):1801-6.
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