MEDICAL SERVICES

EDUCATION

Medical School

  • School of Medicine, Santiago de Guayaquil Catholic University , 1992 , Guayaquil , Ecuador

Internship

  • University of Florida, Schands Teaching Hospital , 1995 , Gainesville , FL

Residency

Pediatrics
  • University of Florida, Schands Teaching Hospital , 1997 , Gainesville , FL

Fellowship

Neonatal-Perinatal Medicine
  • University of Florida, Shands Teaching Hospital , 2000 , Gainesville , FL

Philosophy of Care

In the Boston Children’s Hospital (BCH) Neonatal Intensive Care Unit (NICU) our philosophy is to ensure that every patient receives the best care for the best possible outcomes. We consider our “patient” to be the baby and the family; we are constantly striving to serve the needs of both. This requires a team based approach with all members being essential.

CERTIFICATIONS

  • American Board of Pediatrics, Neonatal-Perinatal Medicine

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Cakir B, Liegl R, Hellgren G, Lundgren P, Sun Y, Klevebro S, Löfqvist C, Mannheimer C, Cho S, Poblete A, Duran R, Hallberg B, Canas J, Lorenz V, Liu ZJ, Sola-Visner MC, Smith LE, Hellström A. Thrombocytopenia is associated with severe retinopathy of prematurity. JCI Insight. 2018 Oct 04; 3(19). View abstract
  2. Liu NN, Uppuluri P, Broggi A, Besold A, Ryman K, Kambara H, Solis N, Lorenz V, Qi W, Acosta-Zaldívar M, Emami SN, Bao B, An D, Bonilla FA, Sola-Visner M, Filler SG, Luo HR, Engström Y, Ljungdahl PO, Culotta VC, Zanoni I, Lopez-Ribot JL, Köhler JR. Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence. PLoS Pathog. 2018 Jul; 14(7):e1007076. View abstract
  3. Lorenz V, Ramsey H, Liu ZJ, Italiano J, Hoffmeister K, Bihorel S, Mager D, Hu Z, Slayton WB, Kile BT, Sola-Visner M, Ferrer-Marin F. Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice. Thromb Haemost. 2017 Dec; 117(12):2322-2333. View abstract
  4. Caparrós-Pérez E, Teruel-Montoya R, Palma-Barquero V, Torregrosa JM, Blanco JE, Delgado JL, Lozano ML, Vicente V, Sola-Visner M, Rivera J, Martínez C, Ferrer-Marín F. Down Regulation of the Munc18b-syntaxin-11 Complex and ß1-tubulin Impairs Secretion and Spreading in Neonatal Platelets. Thromb Haemost. 2017 Nov; 117(11):2079-2091. View abstract
  5. Vlachodimitropoulou E, Chen YL, Garbowski M, Koonyosying P, Psaila B, Sola-Visner M, Cooper N, Hider R, Porter J. Eltrombopag: a powerful chelator of cellular or extracellular iron(III) alone or combined with a second chelator. Blood. 2017 10 26; 130(17):1923-1933. View abstract
  6. Machlus KR, Wu SK, Vijey P, Soussou TS, Liu ZJ, Shacham E, Unger TJ, Kashyap T, Klebanov B, Sola-Visner M, Crochiere M, Italiano JE, Landesman Y. Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis. Blood. 2017 08 31; 130(9):1132-1143. View abstract
  7. Sparger KA, Ramsey H, Lorenz V, Liu ZJ, Feldman HA, Li N, Laforest T, Sola-Visner MC. Developmental differences between newborn and adult mice in response to romiplostim. Platelets. 2018 Jun; 29(4):365-372. View abstract
  8. MacQueen BC, Christensen RD, Henry E, Romrell AM, Pysher TJ, Bennett ST, Sola-Visner MC. The immature platelet fraction: creating neonatal reference intervals and using these to categorize neonatal thrombocytopenias. J Perinatol. 2017 Jul; 37(7):834-838. View abstract
  9. Wheeler CR, Smallwood CD, O'Donnell I, Gagner D, Sola-Visner MC. Assessing Initial Response to High-Frequency Jet Ventilation in Premature Infants With Hypercapnic Respiratory Failure. Respir Care. 2017 Jul; 62(7):867-872. View abstract
  10. Cure P, Bembea M, Chou S, Doctor A, Eder A, Hendrickson J, Josephson CD, Mast AE, Savage W, Sola-Visner M, Spinella P, Stanworth S, Steiner M, Mondoro T, Zou S, Levy C, Waclawiw M, El Kassar N, Glynn S, Luban NLC. 2016 proceedings of the National Heart, Lung, and Blood Institute's scientific priorities in pediatric transfusion medicine. Transfusion. 2017 06; 57(6):1568-1581. View abstract
  11. Bastian TW, Duck KA, Michalopoulos GC, Chen MJ, Liu ZJ, Connor JR, Lanier LM, Sola-Visner MC, Georgieff MK. Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain barrier and impairs iron-dependent hippocampal neuron dendrite development. J Thromb Haemost. 2017 03; 15(3):565-574. View abstract
  12. Sparger KA, Assmann SF, Granger S, Winston A, Christensen RD, Widness JA, Josephson C, Stowell SR, Saxonhouse M, Sola-Visner M. Platelet Transfusion Practices Among Very-Low-Birth-Weight Infants. JAMA Pediatr. 2016 07 01; 170(7):687-94. View abstract
  13. Sola-Visner M, Bercovitz RS. Neonatal Platelet Transfusions and Future Areas of Research. Transfus Med Rev. 2016 10; 30(4):183-8. View abstract
  14. Jabara HH, Boyden SE, Chou J, Ramesh N, Massaad MJ, Benson H, Bainter W, Fraulino D, Rahimov F, Sieff C, Liu ZJ, Alshemmari SH, Al-Ramadi BK, Al-Dhekri H, Arnaout R, Abu-Shukair M, Vatsayan A, Silver E, Ahuja S, Davies EG, Sola-Visner M, Ohsumi TK, Andrews NC, Notarangelo LD, Fleming MD, Al-Herz W, Kunkel LM, Geha RS. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016 Jan; 48(1):74-8. View abstract
  15. Arthur CM, Patel SR, Mener A, Kamili NA, Fasano RM, Meyer E, Winkler AM, Sola-Visner M, Josephson CD, Stowell SR. Innate immunity against molecular mimicry: Examining galectin-mediated antimicrobial activity. Bioessays. 2015 Dec; 37(12):1327-37. View abstract
  16. Christensen RD, Baer VL, Henry E, Snow GL, Butler A, Sola-Visner MC. Thrombocytopenia in Small-for-Gestational-Age Infants. Pediatrics. 2015 Aug; 136(2):e361-70. View abstract
  17. Liu ZJ, Bussel JB, Lakkaraja M, Ferrer-Marin F, Ghevaert C, Feldman HA, McFarland JG, Chavda C, Sola-Visner M. Suppression of in vitro megakaryopoiesis by maternal sera containing anti-HPA-1a antibodies. Blood. 2015 Sep 03; 126(10):1234-6. View abstract
  18. Sparger K, Deschmann E, Sola-Visner M. Platelet Transfusions in the Neonatal Intensive Care Unit. Clin Perinatol. 2015 Sep; 42(3):613-23. View abstract
  19. Debrincat MA, Pleines I, Lebois M, Lane RM, Holmes ML, Corbin J, Vandenberg CJ, Alexander WS, Ng AP, Strasser A, Bouillet P, Sola-Visner M, Kile BT, Josefsson EC. BCL-2 is dispensable for thrombopoiesis and platelet survival. Cell Death Dis. 2015 Apr 16; 6:e1721. View abstract
  20. Wallin DJ, Tkac I, Stucker S, Ennis KM, Sola-Visner M, Rao R, Georgieff MK. Phlebotomy-induced anemia alters hippocampal neurochemistry in neonatal mice. Pediatr Res. 2015 Jun; 77(6):765-71. View abstract
  21. Bender M, Thon JN, Ehrlicher AJ, Wu S, Mazutis L, Deschmann E, Sola-Visner M, Italiano JE, Hartwig JH. Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein. Blood. 2015 Jan 29; 125(5):860-8. View abstract
  22. Kulshrestha M, Sola-Visner M, Widness JA, Veng-Pedersen P, Mager DE. Mathematical model of platelet turnover in thrombocytopenic and nonthrombocytopenic preterm neonates. Am J Physiol Heart Circ Physiol. 2015 Jan 01; 308(1):H68-73. View abstract
  23. Shi DS, Smith MC, Campbell RA, Zimmerman PW, Franks ZB, Kraemer BF, Machlus KR, Ling J, Kamba P, Schwertz H, Rowley JW, Miles RR, Liu ZJ, Sola-Visner M, Italiano JE, Christensen H, Kahr WH, Li DY, Weyrich AS. Proteasome function is required for platelet production. J Clin Invest. 2014 Sep; 124(9):3757-66. View abstract
  24. Liu ZJ, Hoffmeister KM, Hu Z, Mager DE, Ait-Oudhia S, Debrincat MA, Pleines I, Josefsson EC, Kile BT, Italiano J, Ramsey H, Grozovsky R, Veng-Pedersen P, Chavda C, Sola-Visner M. Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan. Blood. 2014 May 29; 123(22):3381-9. View abstract
  25. Ferrer-Marin F, Gutti R, Liu ZJ, Sola-Visner M. MiR-9 contributes to the developmental differences in CXCR-4 expression in human megakaryocytes. J Thromb Haemost. 2014 Feb; 12(2):282-5. View abstract
  26. Köhler JR, Sola-Visner M. The silent crisis: children hurt by current immigration enforcement policies. JAMA Pediatr. 2014 Feb; 168(2):103-4. View abstract
  27. Ferrer-Marin F, Gutti R, Liu ZJ, Sola-Visner M. MiR-9 contributes to the developmental differences in CXCR-4 expression in human megakaryocytes. J Thromb Haemost. 2014 Feb; 12(2):282-285. View abstract
  28. Deschmann E, Sola-Visner M, Saxonhouse MA. Primary hemostasis in neonates with thrombocytopenia. J Pediatr. 2014 Jan; 164(1):167-72. View abstract
  29. Ferrer-Marin F, Stanworth S, Josephson C, Sola-Visner M. Distinct differences in platelet production and function between neonates and adults: implications for platelet transfusion practice. Transfusion. 2013 Nov; 53(11):2814-21; quiz 2813. View abstract
  30. Sola-Visner M. Prognostic significance of low-grade intraventricular hemorrhage in the current era of neonatology. JAMA Pediatr. 2013 May; 167(5):487-8. View abstract
  31. Christensen RD, Yaish HM, Leon EL, Sola-Visner MC, Agrawal PB. A de novo T73I mutation in PTPN11 in a neonate with severe and prolonged congenital thrombocytopenia and Noonan syndrome. Neonatology. 2013; 104(1):1-5. View abstract
  32. Fuchs DA, McGinn SG, Cantu CL, Klein RR, Sola-Visner MC, Rimsza LM. Developmental differences in megakaryocyte size in infants and children. Am J Clin Pathol. 2012 Jul; 138(1):140-5. View abstract
  33. Cooper ST, Richters KE, Melin TE, Liu ZJ, Hordyk PJ, Benrud RR, Geiser LR, Cash SE, Simon Shelley C, Howard DR, Ereth MH, Sola-Visner MC. The hibernating 13-lined ground squirrel as a model organism for potential cold storage of platelets. Am J Physiol Regul Integr Comp Physiol. 2012 May 15; 302(10):R1202-8. View abstract
  34. Sallmon H, Sola-Visner M. Clinical and research issues in neonatal anemia and thrombocytopenia. Curr Opin Pediatr. 2012 Feb; 24(1):16-22. View abstract
  35. Sola-Visner M. Platelets in the neonatal period: developmental differences in platelet production, function, and hemostasis and the potential impact of therapies. Hematology Am Soc Hematol Educ Program. 2012; 2012:506-11. View abstract
  36. Liu ZJ, Sola-Visner M. Neonatal and adult megakaryopoiesis. Curr Opin Hematol. 2011 Sep; 18(5):330-7. View abstract
  37. Sola-Visner M. Cardiovascular disease and weight ... at birth. Blood. 2011 Aug 11; 118(6):1439-41. View abstract
  38. Cremer M, Sola-Visner M, Roll S, Josephson CD, Yilmaz Z, Bührer C, Dame C. Platelet transfusions in neonates: practices in the United States vary significantly from those in Austria, Germany, and Switzerland. Transfusion. 2011 Dec; 51(12):2634-41. View abstract
  39. Ferrer-Marin F, Chavda C, Lampa M, Michelson AD, Frelinger AL, Sola-Visner M. Effects of in vitro adult platelet transfusions on neonatal hemostasis. J Thromb Haemost. 2011 May; 9(5):1020-8. View abstract
  40. Liu ZJ, Italiano J, Ferrer-Marin F, Gutti R, Bailey M, Poterjoy B, Rimsza L, Sola-Visner M. Developmental differences in megakaryocytopoiesis are associated with up-regulated TPO signaling through mTOR and elevated GATA-1 levels in neonatal megakaryocytes. Blood. 2011 Apr 14; 117(15):4106-17. View abstract
  41. Josephson CD, Wesolowski A, Bao G, Sola-Visner MC, Dudell G, Castillejo MI, Shaz BH, Easley KA, Hillyer CD, Maheshwari A. Do red cell transfusions increase the risk of necrotizing enterocolitis in premature infants? J Pediatr. 2010 Dec; 157(6):972-978.e1-3. View abstract
  42. Ferrer-Marin F, Liu ZJ, Gutti R, Sola-Visner M. Neonatal thrombocytopenia and megakaryocytopoiesis. Semin Hematol. 2010 Jul; 47(3):281-8. View abstract
  43. Sallmon H, Gutti RK, Ferrer-Marin F, Liu ZJ, Sola-Visner MC. Increasing platelets without transfusion: is it time to introduce novel thrombopoietic agents in neonatal care? J Perinatol. 2010 Dec; 30(12):765-9. View abstract
  44. Hu Z, Slayton WB, Rimsza LM, Bailey M, Sallmon H, Sola-Visner MC. Differences between newborn and adult mice in their response to immune thrombocytopenia. Neonatology. 2010 Jun; 98(1):100-8. View abstract
  45. Poterjoy BS, Vibert Y, Sola-Visner M, McGowan J, Visner G, Nogee LM. Neonatal respiratory failure due to a novel mutation in the surfactant protein C gene. J Perinatol. 2010 Feb; 30(2):151-3. View abstract
  46. Osei-Bimpong A, Saleh M, Sola-Visner M, Widness J, Veng-Pedersen P. Correction for effect of cold storage on immature platelet fraction. J Clin Lab Anal. 2010; 24(6):431-3. View abstract
  47. Saxonhouse MA, Garner R, Mammel L, Li Q, Muller KE, Greywoode J, Miller C, Sola-Visner M. Closure times measured by the platelet function analyzer PFA-100 are longer in neonatal blood compared to cord blood samples. Neonatology. 2010; 97(3):242-9. View abstract
  48. Gerday E, Baer VL, Lambert DK, Paul DA, Sola-Visner MC, Pysher TJ, Christensen RD. Testing platelet mass versus platelet count to guide platelet transfusions in the neonatal intensive care unit. Transfusion. 2009 Oct; 49(10):2034-9. View abstract
  49. Bussel JB, Sola-Visner M. Current approaches to the evaluation and management of the fetus and neonate with immune thrombocytopenia. Semin Perinatol. 2009 Feb; 33(1):35-42. View abstract
  50. Sola-Visner M. Hematologic Issues. Introduction. Semin Perinatol. 2009 Feb; 33(1):1-2. View abstract
  51. Sola-Visner M, Sallmon H, Brown R. New insights into the mechanisms of nonimmune thrombocytopenia in neonates. Semin Perinatol. 2009 Feb; 33(1):43-51. View abstract
  52. Josephson CD, Su LL, Christensen RD, Hillyer CD, Castillejo MI, Emory MR, Lin Y, Hume H, Easley K, Poterjoy B, Sola-Visner M. Platelet transfusion practices among neonatologists in the United States and Canada: results of a survey. Pediatrics. 2009 Jan; 123(1):278-85. View abstract
  53. Brown RE, Rimsza LM, Pastos K, Young L, Saxonhouse MA, Bailey M, Lawrence RM, Sola-Visner MC. Effects of sepsis on neonatal thrombopoiesis. Pediatr Res. 2008 Oct; 64(4):399-404. View abstract
  54. Wiedmeier SE, Henry E, Sola-Visner MC, Christensen RD. Platelet reference ranges for neonates, defined using data from over 47,000 patients in a multihospital healthcare system. J Perinatol. 2009 Feb; 29(2):130-6. View abstract
  55. Flaumenhaft R, Dilks JR, Richardson J, Alden E, Patel-Hett SR, Battinelli E, Klement GL, Sola-Visner M, Italiano JE. Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles. Blood. 2009 Jan 29; 113(5):1112-21. View abstract
  56. Christensen RD, Paul DA, Sola-Visner MC, Baer VL. Improving platelet transfusion practices in the neonatal intensive care unit. Transfusion. 2008 Nov; 48(11):2281-4. View abstract
  57. Slayton WB, Patel M, Sola-Visner M, Harris N, Rivers A, Montgomery RR, Friedman KD. Type 2B von Willebrand disease associated with the release of platelet agglutinates from megakaryocytes in the bone marrow. J Pediatr Hematol Oncol. 2008 Sep; 30(9):708-11. View abstract
  58. Sola-Visner M, Saxonhouse MA, Brown RE. Neonatal thrombocytopenia: what we do and don't know. Early Hum Dev. 2008 Aug; 84(8):499-506. View abstract
  59. Baer VL, Lambert DK, Henry E, Snow GL, Sola-Visner MC, Christensen RD. Do platelet transfusions in the NICU adversely affect survival? Analysis of 1600 thrombocytopenic neonates in a multihospital healthcare system. J Perinatol. 2007 Dec; 27(12):790-6. View abstract
  60. Li XM, Hu Z, Sola-Visner M, Hensel S, Garner R, Zafar AB, Wingard JR, Jorgensen ML, Fisher RC, Scott EW, Slayton WB. Sites and kinetics of donor thrombopoiesis following transplantation of whole bone marrow and progenitor subsets. Exp Hematol. 2007 Oct; 35(10):1567-79. View abstract
  61. Lambert MP, Rauova L, Bailey M, Sola-Visner MC, Kowalska MA, Poncz M. Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications. Blood. 2007 Aug 15; 110(4):1153-60. View abstract
  62. Sola-Visner MC, Christensen RD, Hutson AD, Rimsza LM. Megakaryocyte size and concentration in the bone marrow of thrombocytopenic and nonthrombocytopenic neonates. Pediatr Res. 2007 Apr; 61(4):479-84. View abstract
  63. Ignatz M, Sola-Visner M, Rimsza LM, Fuchs D, Shuster JJ, Li XM, Jotwani A, Staba S, Wingard JR, Hu Z, Slayton WB. Umbilical cord blood produces small megakaryocytes after transplantation. Biol Blood Marrow Transplant. 2007 Feb; 13(2):145-50. View abstract
  64. Pastos KM, Slayton WB, Rimsza LM, Young L, Sola-Visner MC. Differential effects of recombinant thrombopoietin and bone marrow stromal-conditioned media on neonatal versus adult megakaryocytes. Blood. 2006 Nov 15; 108(10):3360-2. View abstract
  65. Christensen RD, Henry E, Wiedmeier SE, Stoddard RA, Sola-Visner MC, Lambert DK, Kiehn TI, Ainsworth S. Thrombocytopenia among extremely low birth weight neonates: data from a multihospital healthcare system. J Perinatol. 2006 Jun; 26(6):348-53. View abstract