Medical School

  • Madras University , 1988 , Chennai , India


General Surgery
  • Brigham and Women's Hospital , 2001 , Boston , MA


  • Boston Children's Hospital , 2003 , Boston , MA


Cardiothoracic Surgery
  • Brigham and Women's Hosital , 2005 , Boston , MA


Cardiac Surgery
  • Boston Children's Hospital , 2005 , Boston , MA


Cardiac Research
  • Boston Children's Hospital , 2010 , Boston , MA

Graduate Degree

  • Harvard T. H. Chang School of Public Health , 2016 , Boston , MA


I am a pediatric cardiac surgeon primarily involved in clinical research and teaching medical students and residents. I have over 10 years of research experience encompassing the period of my residency training and current faculty position. I have been actively involved in research and teaching throughout my career and as a junior faculty I have mentored undergraduate premed students and medical students through summer internships in outcomes research. I have successfully graduated with an MPH degree from the Harvard TH Chang School of Public Health with my area of interest being clinical effectiveness. My research focus is on clinical outcomes and quality improvement. As a surgeon involved in clinical health services research, I am using my expertise as a pediatric cardiac surgeon to innovate in this field.


  • American Board of Thoracic Surgery
  • American Board of Thoracic Surgery, Congenital Heart Surgery


Publications powered by Harvard Catalyst Profiles

  1. Carlson L, Pickard S, Gauvreau K, Baird C, Geva T, Nido PD, Nathan M. Preoperative Factors That Predict Recurrence after Repair of Discrete Subaortic Stenosis. Ann Thorac Surg. 2020 Jul 23. View abstract
  2. Muter A, Evans HM, Gauvreau K, Colan S, Newburger J, Del Nido PJ, Nathan M. Technical Performance Score's Association with Arterial Switch Operation Outcomes. Ann Thorac Surg. 2020 Jun 27. View abstract
  3. Tan C, Nathan M. Commentary: Approach With Caution - Aorto Right Ventricular Tunnel. Semin Thorac Cardiovasc Surg. 2020 Jun 17. View abstract
  4. IJsselhof RJ, Slieker MG, Gauvreau K, Muter A, Marx GR, Hazekamp MG, Accord R, van Wetten H, van Leeuwen W, Haas F, Schoof PH, Nathan M. Mechanical Mitral Valve Replacement: A Multicenter Study of Outcomes with Use of 15-17 mm Prostheses. Ann Thorac Surg. 2020 Jun 07. View abstract
  5. Anderson BR, Gotlieb EG, Hill K, McHugh KE, Scheurer MA, Mery CM, Pelletier GJ, Kaltman JR, White OJ, Trachtenberg FL, Hollenbeck-Pringle D, McCrindle BW, Sylvester DM, Eckhauser AW, Pasquali SK, Anderson JB, Schamberger MS, Shashidharan S, Jacobs JP, Jacobs ML, Boskovski M, Newburger JW, Nathan M. Registry-based trials: a potential model for cost savings? Cardiol Young. 2020 Jun; 30(6):807-817. View abstract
  6. Ijsselhof R, Gauvreau K, Nido PD, Nathan M. Atrioventricular Valve Function Predicts Reintervention in Complete Atrioventricular Septal Defect. World J Pediatr Congenit Heart Surg. 2020 03; 11(2):247-248. View abstract
  7. Nathan M, Trachtenberg FL, Van Rompay MI, Gaynor W, Kanter K, Ohye R, Bacha EA, Tweddell J, Schwartz SM, Minich LL, Mery CM, Colan SD, Levine J, Lambert LM, Newburger JW. The Pediatric Heart Network Residual Lesion Score Study: Design and objectives. J Thorac Cardiovasc Surg. 2020 07; 160(1):218-223.e1. View abstract
  8. Roy N, Parra MF, Brown ML, Sleeper LA, Nathan M, Sefton BA, Baird CW, Mistry KP, Del Nido PJ. Initial experience introducing an enhanced recovery program in congenital cardiac surgery. J Thorac Cardiovasc Surg. 2019 Oct 24. View abstract
  9. Prospero CJ, Trachtenberg FL, Pemberton VL, Pasquali SK, Anderson BR, Ash KE, Bainton J, Dunbar-Masterson C, Graham EM, Hamstra MS, Hollenbeck-Pringle D, Jacobs JP, Jacobs ML, John R, Lambert LM, Oster ME, Swan E, Waldron A, Nathan M. Lessons learned in the use of clinical registry data in a multi-centre prospective study: the Pediatric Heart Network Residual Lesion Score Study. Cardiol Young. 2019 Jul; 29(7):930-938. View abstract
  10. Straka N, Gauvreau K, Allan C, Jacobs ML, Pasquali SK, Jacobs JP, Mayer JE, Quinonez L, Newburger JW, Thiagarajan R, Nathan M. Factors Associated With Adverse Outcomes After Repair of Anomalous Coronary From Pulmonary Artery. Ann Thorac Surg. 2019 09; 108(3):785-791. View abstract
  11. Nathan M. The left atrioventricular valve: The Achilles' heel of incomplete endocardial cushion defects. J Thorac Cardiovasc Surg. 2018 Nov 08. View abstract
  12. Alexander PMA, DiOrio M, Andren K, Gauvreau K, Mistry KP, Mathieu D, Wright J, Allan CK, Nathan M, Mayer JE, Thiagarajan RR, Bergersen L. Accurate Prediction of Congenital Heart Surgical Length of Stay Incorporating a Procedure-Based Categorical Variable. Pediatr Crit Care Med. 2018 10; 19(10):949-956. View abstract
  13. Nathan M. Neoaortic Root Incorporation of Anomalous Left Coronary Artery From Pulmonary Artery in Hypoplastic Left Heart Syndrome: An Alternative Technique. Semin Thorac Cardiovasc Surg. 2018; 30(4):460-461. View abstract
  14. IJsselhof R, Liu H, Pigula F, Gauvreau K, Mayer JE, Nido PD, Nathan M. Rates of Interventions in Isolated Coarctation Repair in Neonates Versus Infants: Does Age Matter? Ann Thorac Surg. 2019 01; 107(1):180-186. View abstract
  15. Mills KI, van den Bosch SJ, Gauvreau K, Allan CK, Thiagarajan RR, Hoganson DM, Baird CW, Nathan M, DiNardo JA, Kheir JN. Physiologic effects of delayed sternal closure following stage 1 palliation. Cardiol Young. 2018 Dec; 28(12):1393-1403. View abstract
  16. Jolley MA, Hammer PE, Ghelani SJ, Adar A, Sleeper LA, Lacro RV, Marx GR, Nathan M, Harrild DM. Three-Dimensional Mitral Valve Morphology in Children and Young Adults With Marfan Syndrome. J Am Soc Echocardiogr. 2018 11; 31(11):1168-1177.e1. View abstract
  17. Nathan M, Emani S, Del Nido PJ. Reply to Buratto et al. Eur J Cardiothorac Surg. 2018 06 01; 53(6):1296. View abstract
  18. Ubeda Tikkanen A, Nathan M, Sleeper LA, Flavin M, Lewis A, Nimec D, Mayer JE, Del Nido P. Predictors of Postoperative Rehabilitation Therapy Following Congenital Heart Surgery. J Am Heart Assoc. 2018 05 12; 7(10). View abstract
  19. Kuebler JD, Ghelani S, Williams DM, Nathan M, Marx G, Colan SD, Harrild DM. Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. Am J Cardiol. 2018 07 15; 122(2):331-339. View abstract
  20. Nathan M, Tishler B, Gauvreau K, Matte GS, Howe RJ, Durham L, Boyle S, Mathieu D, Fynn-Thompson F, DiNardo JA, Ibla JC. A red cell preservation strategy reduces postoperative transfusions in pediatric heart surgery patients. Paediatr Anaesth. 2018 05; 28(5):450-457. View abstract
  21. Tishler B, Gauvreau K, Colan SD, Del Nido P, Nathan M. Technical Performance Score Predicts Partial/Transitional Atrioventricular Septal Defect Outcomes. Ann Thorac Surg. 2018 05; 105(5):1461-1468. View abstract
  22. Hofferberth SC, Nathan M, Marx GR, Lu M, Sleeper LA, Marshall AC, Baird CW, Mayer JE, Del Nido PJ, Emani SM. Valve-sparing repair with intraoperative balloon dilation in tetralogy of Fallot: Midterm results and therapeutic implications. J Thorac Cardiovasc Surg. 2018 03; 155(3):1163-1173.e4. View abstract
  23. Nathan M, Emani S, IJsselhof R, Liu H, Gauvreau K, Del Nido P. Mid-term outcomes in unbalanced complete atrioventricular septal defect: role of biventricular conversion from single-ventricle palliation. Eur J Cardiothorac Surg. 2017 Sep 01; 52(3):565-572. View abstract
  24. Sykes MC, Nathan M, Sanders SP, Gauvreau K, Pigula FA, Rhodes J. Pseudoaneurysm complicating right ventricle-to-pulmonary artery conduit surgery: Incidence and risk factors. J Thorac Cardiovasc Surg. 2017 12; 154(6):2046-2049. View abstract
  25. Martin E, Del Nido PJ, Nathan M. Technical performance scores are predictors of midterm mortality and reinterventions following congenital mitral valve repair. Eur J Cardiothorac Surg. 2017 Aug 01; 52(2):218-224. View abstract
  26. IJsselhof R, Gauvreau K, Del Nido P, Nathan M. Technical Performance Score: Predictor of Outcomes in Complete Atrioventricular Septal Defect Repair. Ann Thorac Surg. 2017 Oct; 104(4):1371-1377. View abstract
  27. Brennan A, Gauvreau K, Connor J, Almodovar M, DiNardo J, Banka P, Nathan M, Mathieu D, Kaza A, Mayer JE, Bergersen L. A Method to Account for Variation in Congenital Heart Surgery Length of Stay. Pediatr Crit Care Med. 2017 Jun; 18(6):550-560. View abstract
  28. Blinder JJ, Thiagarajan R, Williams K, Nathan M, Mayer J, Kulik TJ. Duration of Mechanical Ventilation and Perioperative Care Quality After Neonatal Cardiac Operations. Ann Thorac Surg. 2017 Jun; 103(6):1956-1962. View abstract
  29. Baird CW, Myers PO, Piekarski B, Borisuk M, Majeed A, Emani SM, Sanders SP, Nathan M, Del Nido PJ. Photo-oxidized bovine pericardium in congenital cardiac surgery: single-centre experience. Interact Cardiovasc Thorac Surg. 2017 02 01; 24(2):240-244. View abstract
  30. Nathan M. A rare triple threat: Rat bite fever, endocarditis of ventricular septal defect patch, and multivalve endocarditis with sinus of Valsalva fistula. J Thorac Cardiovasc Surg. 2017 03; 153(3):e47-e48. View abstract
  31. Howard TS, Kalish BT, Wigmore D, Nathan M, Kulik TJ, Kaza AK, Williams K, Thiagarajan RR. Association of Extracorporeal Membrane Oxygenation Support Adequacy and Residual Lesions With Outcomes in Neonates Supported After Cardiac Surgery. Pediatr Crit Care Med. 2016 11; 17(11):1045-1054. View abstract
  32. Parthiban A, Levine JC, Nathan M, Marshall JA, Shirali GS, Simon SD, Colan SD, Newburger JW, Raghuveer G. Implementation of a Quality Improvement Bundle Improves Echocardiographic Imaging after Congenital Heart Surgery in Children. J Am Soc Echocardiogr. 2016 12; 29(12):1163-1170.e3. View abstract
  33. Nathan M, Jacobs ML, Gaynor JW, Newburger JW, Dunbar Masterson C, Lambert LM, Hollenbeck-Pringle D, Trachtenberg FL, White O, Anderson BR, Bell MC, Burch PT, Graham EM, Kaltman JR, Kanter KR, Mery CM, Pizarro C, Schamberger MS, Taylor MD, Jacobs JP, Pasquali SK. Completeness and Accuracy of Local Clinical Registry Data for Children Undergoing Heart Surgery. Ann Thorac Surg. 2017 Feb; 103(2):629-636. View abstract
  34. Fabozzo A, DiOrio M, Newburger JW, Powell AJ, Liu H, Fynn-Thompson F, Sanders SP, Pigula FA, Del Nido PJ, Nathan M. Anomalous Aortic Origin of Coronary Arteries: A Single-Center Experience. Semin Thorac Cardiovasc Surg. 2016 Winter; 28(4):791-800. View abstract
  35. Nathan M, Gauvreau K, Samnaliev M, Ozonoff A, Jenkins K, Bergersen L, Connor J, Pigula FA, Colan SD, Mayer JE, Del Nido PJ. Technical Performance Score Predicts Resource Utilization in Congenital Cardiac Procedures. J Am Coll Cardiol. 2016 06 07; 67(22):2696-8. View abstract
  36. Thiagarajan RR, Nathan M. Pediatric Index of Cardiac Surgical Intensive Care Mortality: A New Severity of Illness Score for Cardiac Surgical Patients in ICUs. Pediatr Crit Care Med. 2015 Nov; 16(9):885-6. View abstract
  37. Parthiban A, Levine JC, Nathan M, Marshall JA, Shirali GS, Simon SD, Colan SD, Newburger JW, Raghuveer G. Impact of Variability in Echocardiographic Interpretation on Assessment of Adequacy of Repair Following Congenital Heart Surgery: A Pilot Study. Pediatr Cardiol. 2016 Jan; 37(1):144-50. View abstract
  38. Nathan M. Do the benefits outweigh the risks? A review of the history of atrial septal defect repairs and device closures. J Thorac Cardiovasc Surg. 2015 Oct; 150(4):e57-8. View abstract
  39. Dussault C, Toeg H, Nathan M, Wang ZJ, Roux JF, Secemsky E. Electrocardiographic monitoring for detecting atrial fibrillation after ischemic stroke or transient ischemic attack: systematic review and meta-analysis. Circ Arrhythm Electrophysiol. 2015 Apr; 8(2):263-9. View abstract
  40. Stock C, Nathan M, Murray R, Rahbar R, Fynn-Thompson F. Modified end-to-end anastomosis for the treatment of congenital tracheal stenosis with a bridging bronchus. Ann Thorac Surg. 2015 Jan; 99(1):346-8. View abstract
  41. Nathan M, Marshall AC, Kerstein J, Liu H, Fynn-Thompson F, Baird CW, Mayer JE, Pigula FA, del Nido PJ, Emani S. Technical performance score as predictor for post-discharge reintervention in valve-sparing tetralogy of Fallot repair. Semin Thorac Cardiovasc Surg. 2014; 26(4):297-303. View abstract
  42. Villafañe J, Lantin-Hermoso MR, Bhatt AB, Tweddell JS, Geva T, Nathan M, Elliott MJ, Vetter VL, Paridon SM, Kochilas L, Jenkins KJ, Beekman RH, Wernovsky G, Towbin JA. D-transposition of the great arteries: the current era of the arterial switch operation. J Am Coll Cardiol. 2014 Aug 05; 64(5):498-511. View abstract
  43. Nathan M, Gauvreau K, Liu H, Pigula FA, Mayer JE, Colan SD, Del Nido PJ. Outcomes differ in patients who undergo immediate intraoperative revision versus patients with delayed postoperative revision of residual lesions in congenital heart operations. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2540-6.e1-5. View abstract
  44. Nathan M, Sleeper LA, Ohye RG, Frommelt PC, Caldarone CA, Tweddell JS, Lu M, Pearson GD, Gaynor JW, Pizarro C, Williams IA, Colan SD, Dunbar-Masterson C, Gruber PJ, Hill K, Hirsch-Romano J, Jacobs JP, Kaltman JR, Kumar SR, Morales D, Bradley SM, Kanter K, Newburger JW. Technical performance score is associated with outcomes after the Norwood procedure. J Thorac Cardiovasc Surg. 2014 Nov; 148(5):2208-13, 2214.e1-6. View abstract
  45. Baird CW, Myers PO, Borisuk M, Kalish B, Hofferberth S, Nathan M, Emani SM, del Nido PJ. Takedown of cavopulmonary shunt at biventricular repair. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1506-11. View abstract
  46. Nathan M. Late arterial switch operation for transposition with intact septum. World J Pediatr Congenit Heart Surg. 2014 Apr; 5(2):226-8. View abstract
  47. Zaidi AH, Nathan M, Emani S, Baird C, del Nido PJ, Gauvreau K, Harris M, Sanders SP, Padera RF. Preliminary experience with porcine intestinal submucosa (CorMatrix) for valve reconstruction in congenital heart disease: histologic evaluation of explanted valves. J Thorac Cardiovasc Surg. 2014 Nov; 148(5):2216-4, 2225.e1. View abstract
  48. Nathan M, Fabozzo A, Geva T, Walsh E, del Nido PJ. Successful surgical management of ventricular fibromas in children. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2602-8. View abstract
  49. Nathan M, Sadhwani A, Gauvreau K, Agus M, Ware J, Newburger JW, Pigula F. Association between Technical Performance Scores and neurodevelopmental outcomes after congenital cardiac surgery. J Thorac Cardiovasc Surg. 2014 Jul; 148(1):232-237.e3. View abstract
  50. Nathan M, Karamichalis J, Liu H, Gauvreau K, Colan S, Saia M, Pigula F, Fynn-Thompson F, Emani S, Baird C, Mayer JE, del Nido PJ. Technical Performance Scores are strongly associated with early mortality, postoperative adverse events, and intensive care unit length of stay-analysis of consecutive discharges for 2 years. J Thorac Cardiovasc Surg. 2014 Jan; 147(1):389-94, 396.e1-396.e3. View abstract
  51. Nathan M, Pigula FA, Liu H, Gauvreau K, Colan SD, Fynn-Thompson F, Emani S, Baird CA, Mayer JE, Del Nido PJ. Inadequate technical performance scores are associated with late mortality and late reintervention. Ann Thorac Surg. 2013 Aug; 96(2):664-9. View abstract
  52. Nathan M, Liu H, Pigula FA, Fynn-Thompson F, Emani S, Baird CA, Marx G, Mayer JE, Del Nido PJ. Biventricular conversion after single-ventricle palliation in unbalanced atrioventricular canal defects. Ann Thorac Surg. 2013 Jun; 95(6):2086-95; discussion 2095-6. View abstract
  53. Bhalala US, Nishisaki A, McQueen D, Bird GL, Morrison WE, Nadkarni VM, Nathan M, Starr JP. Change in regional (somatic) near-infrared spectroscopy is not a useful indicator of clinically detectable low cardiac output in children after surgery for congenital heart defects. Pediatr Crit Care Med. 2012 Sep; 13(5):529-34. View abstract
  54. Nathan M, Karamichalis JM, Liu H, Emani S, Baird C, Pigula F, Colan S, Thiagarajan RR, Bacha EA, Del Nido P. Surgical technical performance scores are predictors of late mortality and unplanned reinterventions in infants after cardiac surgery. J Thorac Cardiovasc Surg. 2012 Nov; 144(5):1095-1101.e7. View abstract
  55. Karamichalis JM, Colan SD, Nathan M, Pigula FA, Baird C, Marx G, Emani SM, Geva T, Fynn-Thompson FE, Liu H, Mayer JE, del Nido PJ. Technical performance scores in congenital cardiac operations: a quality assessment initiative. Ann Thorac Surg. 2012 Oct; 94(4):1317-23; discussion 1323. View abstract
  56. Nathan M, Williamson AK, Mayer JE, Bacha EA, Juraszek AL. Mortality in hypoplastic left heart syndrome: review of 216 autopsy cases of aortic atresia with attention to coronary artery disease. J Thorac Cardiovasc Surg. 2012 Dec; 144(6):1301-6. View abstract
  57. Nathan M, Karamichalis JM, Liu H, del Nido P, Pigula F, Thiagarajan R, Bacha EA. Intraoperative adverse events can be compensated by technical performance in neonates and infants after cardiac surgery: a prospective study. J Thorac Cardiovasc Surg. 2011 Nov; 142(5):1098-107, 1107.e1-5. View abstract
  58. Nathan M, Emani S, Marx G, Pigula F. Anomalous left coronary artery arising from the pulmonary artery in hypoplastic left hearts: case series and review of literature. J Thorac Cardiovasc Surg. 2011 Jul; 142(1):225-7. View abstract
  59. Nathan M, Camacho M, Hardin JT, Starr JP. Abiomed biventricular assist device as a bridge to transplantation in a 14-year-old with cardiomyopathy resulting from ventricular noncompaction. Pediatr Cardiol. 2010 Nov; 31(8):1249-51. View abstract
  60. Nathan M, Kalyanaraman M, Blank J, Hardin JT, Starr JP. The use of extracorporeal membrane oxygenation, high-frequency oscillatory ventilation, and surfactant for the management of intraoperative acute pulmonary hemorrhage in tetralogy of Fallot. J Cardiothorac Vasc Anesth. 2011 Apr; 25(2):313-5. View abstract
  61. Choi YH, Cowan DB, Nathan M, Poutias D, Stamm C, del Nido PJ, McGowan FX. Myocardial hypertrophy overrides the angiogenic response to hypoxia. PLoS One. 2008; 3(12):e4042. View abstract
  62. Nathan M, Walsh R, Hardin JT, Einzig S, Connor BO, Balaguru D, Verma R, Starr JP. Enteroviral sepsis and ischemic cardiomyopathy in a neonate: case report and review of literature. ASAIO J. 2008 Sep-Oct; 54(5):554-5. View abstract
  63. Robinson BL, Nathan M, Brown DW, Baird C, del Nido PJ. Robotic division of an unusual variant of a right aortic arch. Ann Thorac Surg. 2007 Aug; 84(2):670-3. View abstract
  64. Nathan M, Rimmer D, Piercey G, del Nido PJ, Mayer JE, Bacha EA, Pigula FA. Early repair of hemitruncus: excellent early and late outcomes. J Thorac Cardiovasc Surg. 2007 May; 133(5):1329-35. View abstract
  65. Nathan M, Rimmer D, del Nido PJ, Mayer JE, Bacha EA, Shin A, Regan W, Gonzalez R, Pigula F. Aortic atresia or severe left ventricular outflow tract obstruction with ventricular septal defect: results of primary biventricular repair in neonates. Ann Thorac Surg. 2006 Dec; 82(6):2227-32. View abstract
  66. Nathan M, Baird C, Fynn-Thompson F, Almond C, Thiagarajan R, Laussen P, Blume E, Pigula F. Successful implantation of a Berlin heart biventricular assist device in a failing single ventricle. J Thorac Cardiovasc Surg. 2006 Jun; 131(6):1407-8. View abstract
  67. Aranki SF, Nathan M, Shekar P, Couper G, Rizzo R, Cohn LH. Hypothermic circulatory arrest enables aortic valve replacement in patients with unclampable aorta. Ann Thorac Surg. 2005 Nov; 80(5):1679-86; discussion 1686-7. View abstract
  68. Friehs I, Cao-Danh H, Nathan M, McGowan FX, del Nido PJ. Impaired insulin-signaling in hypertrophied hearts contributes to ischemic injury. Biochem Biophys Res Commun. 2005 May 27; 331(1):15-22. View abstract
  69. Nathan M, Friehs I, Choi YH, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ. Cyclosporin A but not FK-506 protects against dopamine-induced apoptosis in the stunned heart. Ann Thorac Surg. 2005 May; 79(5):1620-6. View abstract
  70. Paul S, Nathan M, Byrne JG, Aranki SF. Transmyocardial laser revascularization. J Cardiothorac Vasc Anesth. 2004 Feb; 18(1):85-92. View abstract
  71. Nathan M, Gates J, Ferzoco SJ. Hepatic duct confluence injury in blunt abdominal trauma: case report and synopsis on management. Surg Laparosc Endosc Percutan Tech. 2003 Oct; 13(5):350-2. View abstract