Joseph Madsen

Joseph Madsen, MD

Director, Epilepsy Surgery; Associate in Neurosurgery

Associate Professor, Harvard Medical School

"I believe in taking my time to talk to patients and charting an individual direction in medicine."

Medical Services

Specialties

  • Brain Tumors
  • Congenital Anomalies
  • Chiari Malformations
  • Fetal Anomalies
  • Neurosurgery
  • Hemispherectomy
  • Hydrocephalus
  • Invasive Phase II Monitoring for Epilepsy
  • Minimally Invasive Laser Surgery
  • Surgical Treatment of Epilepsy
  • Vagal Nerve Stimulator

Departments

  • Neurosurgery

Languages

  • English

Programs

  • Advanced Fetal Care Center
  • Epilepsy Center
  • Hydrocephalus Program
  • Neuromotor Therapy Program
  • Neurosurgical Service
  • Tuberous Sclerosis Program
To schedule an appointment: Call 617-355-6008 or Request an Appointment
Joseph Madsen

I grew up in Salt Lake City, Utah, educated by my father, an engineer, and my mother, a nurse. 

The wide-open vistas of my youth -- with mountains and canyons outside my doorstep -- and the pioneer spirit of the western settlers have had profound influences on my approach to care and research. I believe in taking my time to talk to patients and charting an individual direction in medicine.

I bring a strong interest in engineering, computer programming and mathematics to my practice. An early influence in these areas came during a summer of high school, when I was an intern in the lab of Ed Catmull, then a graduate student at the University of Utah who subsequently founded Pixar, the technology company that changed art, animation and entertainment forever. Thinking about how to approach animation as a computational problem (we were trying to digitize pictures to create a 3D representation of a moving person), I had a chance to think about how cutting-edge computational techniques might dramatically change a field -- and that is something I have tried to bring to neurosurgery.

That interest carries through to today. I hold nine U.S. patents and am interested in creating devices to help my patients. I study epilepsy from a mathematical perspective, using equations to predict specific places in the brain where seizures originate and designing surgeries that can cure them. I teach residents how to bring math, engineering and science to bear on a clinical problem, and stress that thinking this way will lead to better work on every case they undertake.

Experience and Education

Education

Undergraduate Degree

University of Utah, 1976

Salt Lake City, Utah

Medical Degree

Harvard Medical School, 1981

Boston, Massachusetts

Internship

Beth Israel Deaconess Medical Center, 1981-1982

Boston, Massachusetts

Research Fellowship

Beth Israel Deaconess Medical Center, 1982-1983

Boston, Massachusetts

Residency & Fellowship

Massachusetts General Hospital, 1983-1989

Boston, Massachusetts

Certifications

  • ABNS - American Board of Neurological Surgery

  • ABPNS - American Board of Pediatric Neurological Surgery

  • Neurological Surgery, Pediatric Neurological Surgery

Professional History

I am a pediatric neurosurgeon with a strong interest in innovative approaches to the dynamic brain maladies of children, especially epilepsy and hydrocephalus. My clinical efforts are closely tied to my research program, the Neurodynamics Laboratory.

I received my medical degree in 1981 from a joint program poised uniquely at the intersection between engineering and medicine, the Harvard-MIT Program in Health, Science and Technology. I hold the Webster Family Chair in Neurosurgery and Neuroengineering at Boston Children's Hospital, direct the hospital's Epilepsy Surgery Program and am an associate professor at Harvard Medical School. My work is multidisciplinary and focused on applying engineering and mathematical approaches to my practice.

I have brought several innovations to clinical practice. These include a new technique to monitor shunt flow in patients with hydrocephalus, including the use of cardiac-gated MRI scans, thermal detection of shunt flow, and a valve massager technology. I have also developed a new technique to predict seizure focus using intracranial data gathered from implanted electrodes, which will one day allow surgeons like myself to better plan epilepsy surgeries. My practice has grown in part because of successful patient approaches developed during planning of such research programs.

I also have a strong interest in improving pediatric neurosurgery and epilepsy surgery abroad, specifically in China. In that context, I have been an adjunct professor in functional neurosurgery at Xuanwu Hospital, affiliated with Capitol Medical University, Bejing Institute of Functional Neurosurgery. I have been specifically working on a mechanism to review surgical cases in real time with colleagues at Beijing's Children's Hospital.

Research

I lead a multidisciplinary group of researchers in the use of engineering and quantitative principles to better understand and treat children's brains. Through my Neurodynamics Laboratory, I study the biophysics and biology underlying epilepsy and hydrocephalus as well as the use of advanced imaging and radiological tools, mathematical analyses and robotics.

Our lab applies these progressive tools to hydrocephalus and epilepsy research, specifically integrating strides in biology, imaging, mathematics and engineering to provide a much needed framework to these important fields. Recent efforts in our engineering approach have generated new concepts in the fundamental understanding of these conditions, and development of devices to improve care.

In epilepsy, our work has correlated the frequency and phase of specifically recorded intracranial signals with cognitive events, particularly memory and perception. Our current efforts focus on utilizing these methods to improve surgical patient selection and operative resection planning, as well as to understand the mechanisms of nonresective surgical strategies such as vagal nerve stimulation.

In patients evaluated for resective surgery, we assume that there may actually exist an optimal neurosurgical intervention tailored to the individual patient. Techniques of applied mathematics, such as Granger causality calculations on large datasets of intracranial EEG, might allow the most objective practical determination of this intervention.

In hydrocephalus, we have proposed that failure of a mechanism to absorb the kinetic energy of cardiac pulsations may underlie headache and clinical symptoms of hydrocephalus. We have recently published the world’s largest experience with noninvasive thermal measurement of shunt flow, and we now correlate these findings with an MRI-based technique to quantify shunt flow.

Building on a project initiated with Dr. Judah Folkman, we are investigating the levels of VEGF in cerebrospinal fluid, and pursuing a pharmacological strategy resulting from the interplay of these investigations. The impact on diagnosis of shunt problems has led to improved therapy in individual patients and we anticipate therapeutic advances with measurable impact on outcomes for the large population of children with hydrocephalus.

My research has resulted in publications that have advanced the field and provided new options to patients, including:


Sederberg PB, Schulze-Bonhage A, Madsen JR, Bromfield EB, Litt B, Brandt A, Kahana MJ. Gamma oscillations distinguish true from false memories. Psychol Sci. 2007;18:927-932. 


Zou R, Park EH, Kelly EM, Egnor M, Wagshul ME, Madsen JR. Intracranial pressure waves: characterization of a pulsation absorber with notch filter properties using systems analysis: laboratory investigation. J Neurosurg Pediatrics. 2008; 2: 83-94.


Liu H, Buckner RL, Talukdar T, Tanaka N, Madsen JR, Stufflebeam SM. Task-free presurgical mapping using functional magnetic resonance imaging intrinsic activity. J Neurosurg. 2009; 111: 746-754. 


Liu H, Agam Y, Madsen JR, Kreiman G. Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex. Neuron. 2009;62:281-290. 

Grinberg L, Anor T, Cheever E, Madsen JR, Karniadakis GE. Simulation of the human intracranial arterial tree. Philos Transact A Math Phys Eng Sci. 2009; 367: 2371-2386. 

Cash SS, Halgren E, Dehghani N, Rossetti AO, Thesen T, Wang C, Devinsky O, Kuzniecky R, Doyle W, Madsen JR, Bromfield E, Eross L, Halász P, Karmos G, Csercsa R, Wittner L, Ulbert I. The human K-complex represents an isolated cortical down-state. Science. 2009; 324: 1084-1087.
Eide PK, Rapoport BI, Gormley WB, Madsen JR. A dynamic nonlinear relationship between the static and pulsatile components of intracranial pressure in patients with subarachnoid hemorrhage. J Neurosurg. 2010; 112: 616-625. 

Park EH, Dombrowski S, Luciano M, Zurakowski D, Madsen JR. Alterations of pulsation absorber characteristics in experimental hydrocephalus. J Neurosurg Pediatr. 2010; 6:159-170. 

Stufflebeam SM, Liu H, Sepulcre J, Tanaka N, Buckner RL, Madsen JR. Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging. J Neurosurg. 2011; 114: 1693-1697. 

Truccolo W, Donoghue JA, Hochberg LR, Eskandar EN, Madsen JR, Anderson WS, Brown EN, Halgren E, Cash SS. Single-neuron dynamics in human focal epilepsy. Nat Neurosci. 2011; 14: 635-641. 

Poh MZ, Loddenkemper T, Reinsberger C, Swenson NC, Goyal S, Madsen JR, Picard RW. Autonomic changes with seizures correlate with postictal EEG suppression. Neurology. 2012; 78:1868-1876. 

Park EH, Eide PK, Zurakowski D, Madsen JR. Impaired pulsation absorber mechanism in idiopathic normal pressure hydrocephalus. J Neurosurg. 2012; 117:1189-1196. 

Jha RM, Liu X, Chrenek R, Madsen JR, Cardozo DL. The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons. Neurosurgery. 2013; 72: 118-129. 

Duffy FH, Eksioglu YZ, Rotenberg A, Madsen JR, Shankardass A, Als H. The frequency modulated auditory evoked response (FMAER), a technical advance for study of childhood language disorders: cortical source localization and selected case studies. BMC Neurology. 2013; 13: 12. 

Tanaka N, Peters JM, Prohl AK, Takaya S, Madsen JR, Bourgeois BF, Dworetzky BA, Hämäläinen MS, Stufflebeam SM. Clinical value of magnetoencephalographic spike propagation represented by spatiotemporal source analysis: correlation with surgical outcome. Epilepsy Res. 2014; 108: 280-288. 

Shim JW, Sandlund J, Han CH, Hameed MQ, Connors S, Klagsbrun M, Madsen JR, Irwin N. VEGF, which is elevated in the CSF of patients with hydrocephalus, causes ventriculomegaly and ependymal changes in rats. Exp Neurol. 2013; 247:703-709. 


Singer JM, Madsen JR, Anderson WS, Kreiman G. Sensitivity to timing and order in human visual cortex. J Neurophysiol. 2015; 113: 1656-1669.

Publications

Publications powered by Harvard Catalyst Profiles
  1. Sun Y, Lipton JO, Boyle LM, Madsen JR, Goldenberg MC, Pascual-Leone A, Sahin M, Rotenberg A. Direct current stimulation induces mGluR5-dependent neocortical plasticity. Ann Neurol. 2016 Aug; 80(2):233-46.
  2. Kruse CA, Pardo CA, Hartman AL, Jallo G, Vining EP, Voros J, Gaillard WD, Liu J, Oluigbo C, Malone S, Bleasel AF, Dexter M, Micati A, Velasco TR, Machado HR, Martino AM, Huang A, Wheatley BM, Grant GA, Granata T, Freri E, Garbelli R, Koh S, Nordli DR, Campos AR, O'Neill B, Handler MH, Chapman KE, Wilfong AA, Curry DJ, Yaun A, Madsen JR, Smyth MD, Mercer D, Bingaman W, Harvey AS, Leventer RJ, Lockhart PJ, Gillies G, Pope K, Giller CA, Park YD, Rojiani AM, Sharma SJ, Jenkins P, Tung S, Huynh MN, Chirwa TW, Cepeda C, Levine MS, Chang JW, Owens GC, Vinters HV, Mathern GW. Rasmussen encephalitis tissue transfer program. Epilepsia. 2016 Jun; 57(6):1005-7.
  3. Shim JW, Sandlund J, Hameed MQ, Blazer-Yost B, Zhou FC, Klagsbrun M, Madsen JR. Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus. Sci Rep. 2016; 6:26794.
  4. Tang H, Yu HY, Chou CC, Crone NE, Madsen JR, Anderson WS, Kreiman G. Cascade of neural processing orchestrates cognitive control in human frontal cortex. Elife. 2016; 5.
  5. Rehder R, Abd-El-Barr M, Hooten K, Weinstock P, Madsen JR, Cohen AR. The role of simulation in neurosurgery. Childs Nerv Syst. 2016 Jan; 32(1):43-54.
  6. Fox MD, Qian T, Madsen JR, Wang D, Li M, Ge M, Zuo HC, Groppe DM, Mehta AD, Hong B, Liu H. Combining task-evoked and spontaneous activity to improve pre-operative brain mapping with fMRI. Neuroimage. 2016 Jan 1; 124(Pt A):714-23.
  7. Wagner FB, Eskandar EN, Cosgrove GR, Madsen JR, Blum AS, Potter NS, Hochberg LR, Cash SS, Truccolo W. Microscale spatiotemporal dynamics during neocortical propagation of human focal seizures. Neuroimage. 2015 Nov 15; 122:114-30.
  8. Sarkis RA, Thome-Souza S, Poh MZ, Llewellyn N, Klehm J, Madsen JR, Picard R, Pennell PB, Dworetzky BA, Loddenkemper T, Reinsberger C. Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy. Epilepsy Res. 2015 Sep; 115:113-8.
  9. Haahr ME, Hansen DL, Fisher PM, Svarer C, Stenbæk DS, Madsen K, Madsen J, Holst JJ, Baaré WF, Hojgaard L, Almdal T, Knudsen GM. Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals. J Neurosci. 2015 Apr 8; 35(14):5884-9.
  10. Halgren E, Kaestner E, Marinkovic K, Cash SS, Wang C, Schomer DL, Madsen JR, Ulbert I. Laminar profile of spontaneous and evoked theta: Rhythmic modulation of cortical processing during word integration. Neuropsychologia. 2015 Sep; 76:108-24.
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  12. Madhavan R, Millman D, Tang H, Crone NE, Lenz FA, Tierney TS, Madsen JR, Kreiman G, Anderson WS. Decrease in gamma-band activity tracks sequence learning. Front Syst Neurosci. 2014; 8:222.
  13. Vega C, Brenner LA, Madsen J, Bourgeois B, Waber DP, Boyer K. Lexical retrieval pre- and posttemporal lobe epilepsy surgery in a pediatric sample. Epilepsy Behav. 2015 Jan; 42:61-5.
  14. Singer JM, Madsen JR, Anderson WS, Kreiman G. Sensitivity to timing and order in human visual cortex. J Neurophysiol. 2015 Mar 1; 113(5):1656-69.
  15. Suarez RO, Taimouri V, Boyer K, Vega C, Rotenberg A, Madsen JR, Loddenkemper T, Duffy FH, Prabhu SP, Warfield SK. Passive fMRI mapping of language function for pediatric epilepsy surgical planning: validation using Wada, ECS, and FMAER. Epilepsy Res. 2014 Dec; 108(10):1874-88.
  16. Shim JW, Sandlund J, Madsen JR. VEGF: a potential target for hydrocephalus. Cell Tissue Res. 2014 Dec; 358(3):667-83.
  17. Choi H, Madsen JR, Scott RM, Warf BC, Cohen AR, Proctor MR, Huebenthal E, Jernigan SC, Goumnerova L. 183 Intracranial arachnoid cysts and hemorrhage. Neurosurgery. 2014 Aug; 61 Suppl 1:220.
  18. Truccolo W, Ahmed OJ, Harrison MT, Eskandar EN, Cosgrove GR, Madsen JR, Blum AS, Potter NS, Hochberg LR, Cash SS. Neuronal ensemble synchrony during human focal seizures. J Neurosci. 2014 Jul 23; 34(30):9927-44.
  19. Tang H, Buia C, Madhavan R, Crone NE, Madsen JR, Anderson WS, Kreiman G. Spatiotemporal dynamics underlying object completion in human ventral visual cortex. Neuron. 2014 Aug 6; 83(3):736-48.
  20. Boyle TP, Paldino MJ, Kimia AA, Fitz BM, Madsen JR, Monuteaux MC, Nigrovic LE. Comparison of rapid cranial MRI to CT for ventricular shunt malfunction. Pediatrics. 2014 Jul; 134(1):e47-54.
  21. Ginat DT, Swearingen B, Curry W, Cahill D, Madsen J, Schaefer PW. 3 Tesla intraoperative MRI for brain tumor surgery. J Magn Reson Imaging. 2014 Jun; 39(6):1357-65.
  22. Pinto AL, Lohani S, Bergin AM, Bourgeois BF, Black PM, Prabhu SP, Madsen JR, Takeoka M, Poduri A. Surgery for intractable epilepsy due to unilateral brain disease: a retrospective study comparing hemispherectomy techniques. Pediatr Neurol. 2014 Sep; 51(3):336-43.
  23. O'Rourke DJ, Bergin A, Rotenberg A, Peters J, Gorman M, Poduri A, Cryan J, Lidov H, Madsen J, Harini C. Rasmussen's encephalitis presenting as focal cortical dysplasia. Epilepsy Behav Case Rep. 2014; 2:86-9.
  24. Bansal AK, Madhavan R, Agam Y, Golby A, Madsen JR, Kreiman G. Neural dynamics underlying target detection in the human brain. J Neurosci. 2014 Feb 19; 34(8):3042-55.
  25. Tanaka N, Peters JM, Prohl AK, Takaya S, Madsen JR, Bourgeois BF, Dworetzky BA, Hämäläinen MS, Stufflebeam SM. Clinical value of magnetoencephalographic spike propagation represented by spatiotemporal source analysis: correlation with surgical outcome. Epilepsy Res. 2014 Feb; 108(2):280-8.
  26. Yu C, Ramgopal S, Libenson M, Abdelmoumen I, Powell C, Remy K, Madsen JR, Rotenberg A, Loddenkemper T. Outcomes of vagal nerve stimulation in a pediatric population: a single center experience. Seizure. 2014 Feb; 23(2):105-11.
  27. Gross BA, Smith ER, Goumnerova L, Proctor MR, Madsen JR, Scott RM. Resection of supratentorial lobar cavernous malformations in children: clinical article.. J Neurosurg Pediatr. 2013 Oct; 12(4):367-73.
  28. Taimouri V, Akhondi-Asl A, Tomas-Fernandez X, Peters JM, Prabhu SP, Poduri A, Takeoka M, Loddenkemper T, Bergin AM, Harini C, Madsen JR, Warfield SK. Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. Int J Comput Assist Radiol Surg. 2014 Jan; 9(1):91-105.
  29. Lohani S, Madsen JR, Bergin AM, Smith ER. Moyamoya disease with mesial temporal sclerosis. J Neurosurg Pediatr. 2013 Jun; 11(6):713-6.
  30. Aguilar M, Alberti G, Alpat B, Alvino A, Ambrosi G, Andeen K, Anderhub H, Arruda L, Azzarello P, Bachlechner A, Barao F, Baret B, Barrau A, Barrin L, Bartoloni A, Basara L, Basili A, Batalha L, Bates J, Battiston R, Bazo J, Becker R, Becker U, Behlmann M, Beischer B, Berdugo J, Berges P, Bertucci B, Bigongiari G, Biland A, Bindi V, Bizzaglia S, Boella G, de Boer W, Bollweg K, Bolmont J, Borgia B, Borsini S, Boschini MJ, Boudoul G, Bourquin M, Brun P, Buénerd M, Burger J, Burger W, Cadoux F, Cai XD, Capell M, Casadei D, Casaus J, Cascioli V, Castellini G, Cernuda I, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen CR, Chen H, Cheng GM, Chen HS, Cheng L, Chernoplyiokov N, Chikanian A, Choumilov E, Choutko V, Chung CH, Clark C, Clavero R, Coignet G, Commichau V, Consolandi C, Contin A, Corti C, Costado Dios MT, Coste B, Crespo D, Cui Z, Dai M, Delgado C, Della Torre S, Demirkoz B, Dennett P, Derome L, Di Falco S, Diao XH, Diago A, Djambazov L, Díaz C, von Doetinchem P, Du WJ, Dubois JM, Duperay R, Duranti M, D'Urso D, Egorov A, Eline A, Eppling FJ, Eronen T, van Es J, Esser H, Falvard A, Fiandrini E, Fiasson A, Finch E, Fisher P, Flood K, Foglio R, Fohey M, Fopp S, Fouque N, Galaktionov Y, Gallilee M, Gallin-Martel L, Gallucci G, García B, García J, García-López R, García-Tabares L, Gargiulo C, Gast H, Gebauer I, Gentile S, Gervasi M, Gillard W, Giovacchini F, Girard L, Goglov P, Gong J, Goy-Henningsen C, Grandi D, Graziani M, Grechko A, Gross A, Guerri I, de la Guía C, Guo KH, Habiby M, Haino S, Hauler F, He ZH, Heil M, Heilig J, Hermel R, Hofer H, Huang ZC, Hungerford W, Incagli M, Ionica M, Jacholkowska A, Jang WY, Jinchi H, Jongmanns M, Journet L, Jungermann L, Karpinski W, Kim GN, Kim KS, Kirn T, Kossakowski R, Koulemzine A, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, Laudi E, Laurenti G, Lauritzen C, Lebedev A, Lee MW, Lee SC, Leluc C, León Vargas H, Lepareur V, Li JQ, Li Q, Li TX, Li W, Li ZH, Lipari P, Lin CH, Liu D, Liu H, Lomtadze T, Lu YS, Lucidi S, Lübelsmeyer K, Luo JZ, Lustermann W, Lv S, Madsen J, Majka R, Malinin A, Mañá C, Marín J, Martin T, Martínez G, Masciocchi F, Masi N, Maurin D, McInturff A, McIntyre P, Menchaca-Rocha A, Meng Q, Menichelli M, Mereu I, Millinger M, Mo DC, Molina M, Mott P, Mujunen A, Natale S, Nemeth P, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oh S, Oliva A, Palmonari F, Palomares C, Paniccia M, Papi A, Park WH, Pauluzzi M, Pauss F, Pauw A, Pedreschi E, Pensotti S, Pereira R, Perrin E, Pessina G, Pierschel G, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pochon J, Pohl M, Poireau V, Porter S, Pouxe J, Putze A, Quadrani L, Qi XN, Rancoita PG, Rapin D, Ren ZL, Ricol JS, Riihonen E, Rodríguez I, Roeser U, Rosier-Lees S, Rossi L, Rozhkov A, Rozza D, Sabellek A, Sagdeev R, Sandweiss J, Santos B, Saouter P, Sarchioni M, Schael S, Schinzel D, Schmanau M, Schwering G, Schulz von Dratzig A, Scolieri G, Seo ES, Shan BS, Shi JY, Shi YM, Siedenburg T, Siedling R, Son D, Spada F, Spinella F, Steuer M, Stiff K, Sun W, Sun WH, Sun XH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tassan-Viol J, Ting SC, Ting SM, Titus C, Tomassetti N, Toral F, Torsti J, Tsai JR, Tutt JC, Ulbricht J, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vargas Trevino M, Vaurynovich S, Vecchi M, Vergain M, Verlaat B, Vescovi C, Vialle JP, Viertel G, Volpini G, Wang D, Wang NH, Wang QL, Wang RS, Wang X, Wang ZX, Wallraff W, Weng ZL, Willenbrock M, Wlochal M, Wu H, Wu KY, Wu ZS, Xiao WJ, Xie S, Xiong RQ, Xin GM, Xu NS, Xu W, Yan Q, Yang J, Yang M, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang JG, Zhang Z, Zhang MM, Zheng ZM, Zhuang HL, Zhukov V, Zichichi A, Zuccon P, Zurbach C. First result from the Alpha Magnetic Spectrometer on the International Space Station: precision measurement of the positron fraction in primary cosmic rays of 0.5-350 GeV. Phys Rev Lett. 2013 Apr 5; 110(14):141102.
  31. Shim JW, Sandlund J, Han CH, Hameed MQ, Connors S, Klagsbrun M, Madsen JR, Irwin N. VEGF, which is elevated in the CSF of patients with hydrocephalus, causes ventriculomegaly and ependymal changes in rats. Exp Neurol. 2013 Sep; 247:703-9.
  32. Duffy FH, Eksioglu YZ, Rotenberg A, Madsen JR, Shankardass A, Als H. The frequency modulated auditory evoked response (FMAER), a technical advance for study of childhood language disorders: cortical source localization and selected case studies. BMC Neurol. 2013; 13:12.
  33. Jha RM, Liu X, Chrenek R, Madsen JR, Cardozo DL. The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons. Neurosurgery. 2013 Jan; 72(1):118-29; discussion 129.
  34. Sweet A, Venkataraman A, Stufflebeam SM, Liu H, Tanaka N, Madsen J, Golland P. Detecting epileptic regions based on global brain connectivity patterns. Med Image Comput Comput Assist Interv. 2013; 16(Pt 1):98-105.
  35. Kramer MA, Truccolo W, Eden UT, Lepage KQ, Hochberg LR, Eskandar EN, Madsen JR, Lee JW, Maheshwari A, Halgren E, Chu CJ, Cash SS. Human seizures self-terminate across spatial scales via a critical transition. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):21116-21.
  36. Ginat DT, Prabhu SP, Madsen JR. Postshunting corpus callosum swelling with depiction on tractography. J Neurosurg Pediatr. 2013 Feb; 11(2):178-80.
  37. Lewis LD, Weiner VS, Mukamel EA, Donoghue JA, Eskandar EN, Madsen JR, Anderson WS, Hochberg LR, Cash SS, Brown EN, Purdon PL. Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness. Proc Natl Acad Sci U S A. 2012 Dec 4; 109(49):E3377-86.
  38. Park EH, Eide PK, Zurakowski D, Madsen JR. Impaired pulsation absorber mechanism in idiopathic normal pressure hydrocephalus: laboratory investigation. J Neurosurg. 2012 Dec; 117(6):1189-96.
  39. Bansal AK, Singer JM, Anderson WS, Golby A, Madsen JR, Kreiman G. Temporal stability of visually selective responses in intracranial field potentials recorded from human occipital and temporal lobes. J Neurophysiol. 2012 Dec; 108(11):3073-86.
  40. Tanaka N, Liu H, Reinsberger C, Madsen JR, Bourgeois BF, Dworetzky BA, Hämäläinen MS, Stufflebeam SM. Language lateralization represented by spatiotemporal mapping of magnetoencephalography. AJNR Am J Neuroradiol. 2013 Mar; 34(3):558-63.
  41. Rogers EA, Kimia A, Madsen JR, Nigrovic LE, Neuman MI. Predictors of ventricular shunt infection among children presenting to a pediatric emergency department. Pediatr Emerg Care. 2012 May; 28(5):405-9.
  42. Poh MZ, Loddenkemper T, Reinsberger C, Swenson NC, Goyal S, Madsen JR, Picard RW. Autonomic changes with seizures correlate with postictal EEG suppression. Neurology. 2012 Jun 5; 78(23):1868-76.
  43. Talos DM, Sun H, Kosaras B, Joseph A, Folkerth RD, Poduri A, Madsen JR, Black PM, Jensen FE. Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. Ann Neurol. 2012 Apr; 71(4):539-51.
  44. Poh MZ, Loddenkemper T, Reinsberger C, Swenson NC, Goyal S, Sabtala MC, Madsen JR, Picard RW. Convulsive seizure detection using a wrist-worn electrodermal activity and accelerometry biosensor. Epilepsia. 2012 May; 53(5):e93-7.
  45. Peyrache A, Dehghani N, Eskandar EN, Madsen JR, Anderson WS, Donoghue JA, Hochberg LR, Halgren E, Cash SS, Destexhe A. Spatiotemporal dynamics of neocortical excitation and inhibition during human sleep. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1731-6.
  46. Dykstra AR, Chan AM, Quinn BT, Zepeda R, Keller CJ, Cormier J, Madsen JR, Eskandar EN, Cash SS. Individualized localization and cortical surface-based registration of intracranial electrodes. Neuroimage. 2012 Feb 15; 59(4):3563-70.
  47. Tanaka N, Grant PE, Suzuki N, Madsen JR, Bergin AM, Hämäläinen MS, Stufflebeam SM. Multimodal imaging of spike propagation: a technical case report. AJNR Am J Neuroradiol. 2012 Jun; 33(6):E82-4.
  48. Dykstra AR, Halgren E, Thesen T, Carlson CE, Doyle W, Madsen JR, Eskandar EN, Cash SS. Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG. Front Hum Neurosci. 2011; 5:74.
  49. Ajose-Popoola O, Lin HW, Silvera VM, Teot LA, Madsen JR, Meara JG, Rahbar R. Nasal glioma: prenatal diagnosis and multidisciplinary surgical approach. Skull Base Rep. 2011 Nov; 1(2):83-8.
  50. Truccolo W, Donoghue JA, Hochberg LR, Eskandar EN, Madsen JR, Anderson WS, Brown EN, Halgren E, Cash SS. Single-neuron dynamics in human focal epilepsy. Nat Neurosci. 2011 May; 14(5):635-41.
  51. Stufflebeam SM, Liu H, Sepulcre J, Tanaka N, Buckner RL, Madsen JR. Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging. J Neurosurg. 2011 Jun; 114(6):1693-7.
  52. Wagshul ME, Eide PK, Madsen JR. The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility. Fluids Barriers CNS. 2011; 8(1):5.
  53. Madsen JR, Abazi GS, Fleming L, Proctor M, Grondin R, Magge S, Casey P, Anor T. Evaluation of the ShuntCheck noninvasive thermal technique for shunt flow detection in hydrocephalic patients. Neurosurgery. 2011 Jan; 68(1):198-205; discussion 205.
  54. Magge SN, Smyth MD, Governale LS, Goumnerova L, Madsen J, Munro B, Nalbach SV, Proctor MR, Scott RM, Smith ER. Idiopathic syrinx in the pediatric population: a combined center experience. J Neurosurg Pediatr. 2011 Jan; 7(1):30-6.
  55. Anor T, Grinberg L, Baek H, Madsen JR, Jayaraman MV, Karniadakis GE. Modeling of blood flow in arterial trees. Wiley Interdiscip Rev Syst Biol Med. 2010 Sep-Oct; 2(5):612-23.
  56. Park EH, Dombrowski S, Luciano M, Zurakowski D, Madsen JR. Alterations of pulsation absorber characteristics in experimental hydrocephalus. J Neurosurg Pediatr. 2010 Aug; 6(2):159-70.
  57. Grinberg L, Cheever E, Anor T, Madsen JR, Karniadakis GE. Modeling blood flow circulation in intracranial arterial networks: a comparative 3D/1D simulation study. Ann Biomed Eng. 2011 Jan; 39(1):297-309.
  58. Keller CJ, Truccolo W, Gale JT, Eskandar E, Thesen T, Carlson C, Devinsky O, Kuzniecky R, Doyle WK, Madsen JR, Schomer DL, Mehta AD, Brown EN, Hochberg LR, Ulbert I, Halgren E, Cash SS. Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex. Brain. 2010 Jun; 133(Pt 6):1668-81.
  59. Reinsberger C, Tanaka N, Cole AJ, Lee JW, Dworetzky BA, Bromfield EB, Hamiwka L, Bourgeois BF, Golby AJ, Madsen JR, Stufflebeam SM. Current dipole orientation and distribution of epileptiform activity correlates with cortical thinning in left mesiotemporal epilepsy. Neuroimage. 2010 Oct 1; 52(4):1238-42.
  60. Jacobs J, Korolev IO, Caplan JB, Ekstrom AD, Litt B, Baltuch G, Fried I, Schulze-Bonhage A, Madsen JR, Kahana MJ. Right-lateralized brain oscillations in human spatial navigation. J Cogn Neurosci. 2010 May; 22(5):824-36.
  61. Agam Y, Liu H, Papanastassiou A, Buia C, Golby AJ, Madsen JR, Kreiman G. Robust selectivity to two-object images in human visual cortex. Curr Biol. 2010 May 11; 20(9):872-9.
  62. Eide PK, Rapoport BI, Gormley WB, Madsen JR. A dynamic nonlinear relationship between the static and pulsatile components of intracranial pressure in patients with subarachnoid hemorrhage. J Neurosurg. 2010 Mar; 112(3):616-25.
  63. Eide PK, Park EH, Madsen JR. Arterial blood pressure vs intracranial pressure in normal pressure hydrocephalus. Acta Neurol Scand. 2010 Oct; 122(4):262-9.
  64. Poh MZ, Loddenkemper T, Swenson NC, Goyal S, Madsen JR, Picard RW. Continuous monitoring of electrodermal activity during epileptic seizures using a wearable sensor. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:4415-8.
  65. Tanaka N, Hämäläinen MS, Ahlfors SP, Liu H, Madsen JR, Bourgeois BF, Lee JW, Dworetzky BA, Belliveau JW, Stufflebeam SM. Propagation of epileptic spikes reconstructed from spatiotemporal magnetoencephalographic and electroencephalographic source analysis. Neuroimage. 2010 Mar; 50(1):217-22.
  66. Tanaka N, Thiele EA, Madsen JR, Bourgeois BF, Stufflebeam SM. Magnetoencephalographic analysis in patients with vagus nerve stimulator. Pediatr Neurol. 2009 Nov; 41(5):383-7.
  67. Liu H, Buckner RL, Talukdar T, Tanaka N, Madsen JR, Stufflebeam SM. Task-free presurgical mapping using functional magnetic resonance imaging intrinsic activity. J Neurosurg. 2009 Oct; 111(4):746-54.
  68. Maher CO, Bauer SB, Goumnerova L, Proctor MR, Madsen JR, Scott RM. Urological outcome following multiple repeat spinal cord untethering operations. Clinical article. J Neurosurg Pediatr. 2009 Sep; 4(3):275-9.
  69. Frokjaer VG, Erritzoe D, Madsen J, Paulson OB, Knudsen GM. Gender and the use of hormonal contraception in women are not associated with cerebral cortical 5-HT 2A receptor binding. Neuroscience. 2009 Oct 6; 163(2):640-5.
  70. Grinberg L, Anor T, Cheever E, Madsen JR, Karniadakis GE. Simulation of the human intracranial arterial tree. Philos Trans A Math Phys Eng Sci. 2009 Jun 13; 367(1896):2371-86.
  71. Cash SS, Halgren E, Dehghani N, Rossetti AO, Thesen T, Wang C, Devinsky O, Kuzniecky R, Doyle W, Madsen JR, Bromfield E, Eross L, Halász P, Karmos G, Csercsa R, Wittner L, Ulbert I. The human K-complex represents an isolated cortical down-state. Science. 2009 May 22; 324(5930):1084-7.
  72. Liu H, Agam Y, Madsen JR, Kreiman G. Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex. Neuron. 2009 Apr 30; 62(2):281-90.
  73. Tanaka N, Cole AJ, von Pechmann D, Wakeman DG, Hämäläinen MS, Liu H, Madsen JR, Bourgeois BF, Stufflebeam SM. Dynamic statistical parametric mapping for analyzing ictal magnetoencephalographic spikes in patients with intractable frontal lobe epilepsy. Epilepsy Res. 2009 Aug; 85(2-3):279-86.
  74. Erritzoe D, Frokjaer VG, Haugbol S, Marner L, Svarer C, Holst K, Baaré WF, Rasmussen PM, Madsen J, Paulson OB, Knudsen GM. Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use. Neuroimage. 2009 May 15; 46(1):23-30.
  75. Liu H, BucknerRL, Talukdar T, Tanaka N, Madsen JR, Stufflebeam SM. Task-free presurgical mapping using fMRI intrinsic activity. J Neurosurgery,in press. 2009.
  76. Grinberg L, Anor T, Madsen JR, Yakhot A, Karniadakis GE. Large-scale simulation of the human arterial tree. Clin Exp Pharmacol Physiol. 2009 Feb; 36(2):194-205.
  77. Zou R, Park EH, Kelly EM, Egnor M, Wagshul ME, Madsen JR. Intracranial pressure waves: characterization of a pulsation absorber with notch filter properties using systems analysis: laboratory investigation. J Neurosurg Pediatr. 2008 Jul; 2(1):83-94.
  78. Fricchione G, Zhu W, Cadet P, Mantione KJ, Bromfield E, Madsen J, DeGirolami U, Dworetzky B, Vaccaro B, Black P, Stefano GB. Identification of endogenous morphine and a mu3-like opiate alkaloid receptor in human brain tissue taken from a patient with intractable complex partial epilepsy. Med Sci Monit. 2008 Jun; 14(6):CS45-49.
  79. A. Leland Albright, Ian F. Pollack, P. David Adelson. Nonresective Surgical Management of Refractory Epilepsy: Callosotomy and Vagal Stimulation. Principles and Practice of Pediatric Neurosurgery. 2008.
  80. Sederberg PB, Schulze-Bonhage A, Madsen JR, Bromfield EB, Litt B, Brandt A, Kahana MJ. Gamma oscillations distinguish true from false memories. Psychol Sci. 2007 Nov; 18(11):927-32.
  81. Williams MA, McAllister JP, Walker ML, Kranz DA, Bergsneider M, Del Bigio MR, Fleming L, Frim DM, Gwinn K, Kestle JR, Luciano MG, Madsen JR, Oster-Granite ML, Spinella G. Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshop. J Neurosurg. 2007 Nov; 107(5 Suppl):345-57.
  82. Rotenberg A, Harrington MG, Birnbaum DS, Madsen JR, Glass IE, Jensen FE, Pascual-Leone A. Minimal heating of titanium skull plates during 1Hz repetitive transcranial magnetic stimulation. Clin Neurophysiol. 2007 Nov; 118(11):2536-8.
  83. Madsen JR. Apparatus and method for measuring a human head. 2007.
  84. Maher CO, Goumnerova L, Madsen JR, Proctor M, Scott RM. Outcome following multiple repeated spinal cord untethering operations. J Neurosurg. 2007 Jun; 106(6 Suppl):434-8.
  85. Madsen JR, Scott RM. Treatment of subdural hematomas in infants. J Neurosurg. 2007 Mar; 106(3 Suppl):171.
  86. Black PM, Dello Iacono D, Olsen Bailey N, Madsen J. The emerging field of third circulation research. Clin Neurosurg. 2007; 54:129-33.
  87. Madsen JR, Proctor M, Scott RM, MacLane C, Duffy F, Goumnerova LC, Kieren M, Ligon K, Robson C. MRI and Physiologically Guided Brain Tumor Removal (Live Webcast, ORLive). 2006.
  88. Sederberg PB, Schulze-Bonhage A, Madsen JR, Bromfield EB, McCarthy DC, Brandt A, Tully MS, Kahana MJ. Hippocampal and neocortical gamma oscillations predict memory formation in humans. Cereb Cortex. 2007 May; 17(5):1190-6.
  89. Sarco DP, Burke JF, Madsen JR. Electroencephalography in epilepsy surgery planning. Childs Nerv Syst. 2006 Aug; 22(8):760-5.
  90. Rizzuto DS, Madsen JR, Bromfield EB, Schulze-Bonhage A, Kahana MJ. Human neocortical oscillations exhibit theta phase differences between encoding and retrieval. Neuroimage. 2006 Jul 1; 31(3):1352-8.
  91. Knake S, Halgren E, Shiraishi H, Hara K, Hamer HM, Grant PE, Carr VA, Foxe D, Camposano S, Busa E, Witzel T, Hämäläinen MS, Ahlfors SP, Bromfield EB, Black PM, Bourgeois BF, Cole AJ, Cosgrove GR, Dworetzky BA, Madsen JR, Larsson PG, Schomer DL, Thiele EA, Dale AM, Rosen BR, Stufflebeam SM. The value of multichannel MEG and EEG in the presurgical evaluation of 70 epilepsy patients. Epilepsy Res. 2006 Apr; 69(1):80-6.
  92. Bergsneider M, Egnor MR, Johnston M, Kranz D, Madsen JR, McAllister JP, Stewart C, Walker ML, Williams MA. What we don't (but should) know about hydrocephalus. J Neurosurg. 2006 Mar; 104(3 Suppl):157-9.
  93. Madsen JR, Egnor M, Zou R. Cerebrospinal fluid pulsatility and hydrocephalus: the fourth circulation. Clin Neurosurg. 2006; 53:48-52.
  94. Madsen JR, Louie K. Treatment of refractory epilepsy: General approach and nonresective strategies. Albright L et al, eds., Pediatric Neurosurgery. 2006.
  95. Raghavachari S, Lisman JE, Tully M, Madsen JR, Bromfield EB, Kahana MJ. Theta oscillations in human cortex during a working-memory task: evidence for local generators. J Neurophysiol. 2006 Mar; 95(3):1630-8.
  96. Krach LE, Kriel RL, Gilmartin RC, Swift DM, Storrs BB, Abbott R, Ward JD, Bloom KK, Brooks WH, Madsen JR, McLaughlin JF, Nadell JM. GMFM 1 year after continuous intrathecal baclofen infusion. Pediatr Rehabil. 2005 Jul-Sep; 8(3):207-13.
  97. Ekelund K, Skinhøj P, Madsen J, Konradsen HB. Invasive group A, B, C and G streptococcal infections in Denmark 1999-2002: epidemiological and clinical aspects. Clin Microbiol Infect. 2005 Jul; 11(7):569-76.
  98. Rossetti AO, Dworetzky BA, Madsen JR, Golub O, Beckman JA, Bromfield EB. Ictal asystole with convulsive syncope mimicking secondary generalisation: a depth electrode study. J Neurol Neurosurg Psychiatry. 2005 Jun; 76(6):885-7.
  99. Zou R, McCormack E, Egnor M, Kim D, Wagshul M, Macdonald B, Madsen J. Increased Phase Synchronization between Intracranial Pressure and Arterial Blood Pressure during Elevated Intracranial Pressure in Dogs. Conf Proc IEEE Eng Med Biol Soc. 2005; 1:315-8.
  100. Joseph R. Madsen. Direction-oriented and spatially controlled bipolar for in-situ cauterization of adherent cranial tissue occluding a ventricular catheter previously implanted in-vivo. 2004.
  101. Cantero JL, Atienza M, Madsen JR, Stickgold R. Gamma EEG dynamics in neocortex and hippocampus during human wakefulness and sleep. Neuroimage. 2004 Jul; 22(3):1271-80.
  102. Smith ER, Madsen JR. Neurosurgical aspects of critical care neurology. Semin Pediatr Neurol. 2004 Jun; 11(2):169-78.
  103. Smith ER, Madsen JR. Cerebral pathophysiology and critical care neurology: basic hemodynamic principles, cerebral perfusion, and intracranial pressure. Semin Pediatr Neurol. 2004 Jun; 11(2):89-104.
  104. Hansen AR, Madsen JR. Antenatal neurosurgical counseling: approach to the unborn patient. Pediatr Clin North Am. 2004 Apr; 51(2):491-505.
  105. Krach LE, Kriel RL, Gilmartin RC, Swift DM, Storrs BB, Abbott R, Ward JD, Bloom KK, Brooks WH, Madsen JR, McLaughlin JF, Nadell JM. Hip status in cerebral palsy after one year of continuous intrathecal baclofen infusion. Pediatr Neurol. 2004 Mar; 30(3):163-8.
  106. Scott RM, Smith JL, Robertson RL, Madsen JR, Soriano SG, Rockoff MA. Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosis. J Neurosurg. 2004 Feb; 100(2 Suppl Pediatrics):142-9.
  107. Ulbert I, Heit G, Madsen J, Karmos G, Halgren E. Laminar analysis of human neocortical interictal spike generation and propagation: current source density and multiunit analysis in vivo. Epilepsia. 2004; 45 Suppl 4:48-56.
  108. Hansen AR, Madsen JR. Antenatal Neurosurgical counseling: Approach to the unborn patient. Pedi Clin N Amer. 2004; 51:491-505.
  109. Madsen JR, Rominger A. Treatment of epilepsy by vagal nerve stimulation. Schmidek H, ed., Operative Neurosurgery (in press). 2004.
  110. Howard MW, Rizzuto DS, Caplan JB, Madsen JR, Lisman J, Aschenbrenner-Scheibe R, Schulze-Bonhage A, Kahana MJ. Gamma oscillations correlate with working memory load in humans. Cereb Cortex. 2003 Dec; 13(12):1369-74.
  111. Sederberg PB, Kahana MJ, Howard MW, Donner EJ, Madsen JR. Theta and gamma oscillations during encoding predict subsequent recall. J Neurosci. 2003 Nov 26; 23(34):10809-14.
  112. Cantero JL, Atienza M, Stickgold R, Kahana MJ, Madsen JR, Kocsis B. Sleep-dependent theta oscillations in the human hippocampus and neocortex. J Neurosci. 2003 Nov 26; 23(34):10897-903.
  113. Rizzuto DS, Madsen JR, Bromfield EB, Schulze-Bonhage A, Seelig D, Aschenbrenner-Scheibe R, Kahana MJ. Reset of human neocortical oscillations during a working memory task. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7931-6.
  114. Caplan JB, Madsen JR, Schulze-Bonhage A, Aschenbrenner-Scheibe R, Newman EL, Kahana MJ. Human theta oscillations related to sensorimotor integration and spatial learning. J Neurosci. 2003 Jun 1; 23(11):4726-36.
  115. Akman C, Riviello JJ, Madsen JR, Bergin AM. Pharyngeal dysesthesia in refractory complex partial epilepsy: new seizure or adverse effect of vagal nerve stimulation? Epilepsia. 2003 Jun; 44(6):855-8.
  116. Joseph R. Madsen and George A. Taylor. Non-invasive in vivo pressure measurement. 2003.
  117. Scott RM, Madsen JR. Shunt technology: contemporary concepts and prospects. Clin Neurosurg. 2003; 50:256-67.
  118. Madsen JR, Ohaegbulam C. Carotid and vertebral artery dissections in children and adults. Batjer HH, Loftus CM, eds. Textbook of Neurological Surgery: Principles and Practice. 2003; 1:1121-1127.
  119. Soul JS, Madsen JR. Neonatal hydrocephalus. Hansen AR, Puder M, eds., Manual of Neonatal Surgical Intensive Care. 2003; 381-393.
  120. Scott RM, Madsen JR. Shunt technology: Contemporary concepts and prospects. Contemporary Neurosurgery. 2003.
  121. Madsen JR, Frim DM, Hansen AR. Neurosurgery of the Newborn. Avery GB, Fletcher MA, McDonald MG, eds., Neonatology: Pathophysiology and Management of the Newborn (in press). 2003.
  122. Vyas, NS, Madsen JR. Syringomyelia. Adelman G, Smith BH, eds., Encylcopedia of Neuroscience (in press). 2003.
  123. Madsen JR, Nadig M. Syringomyelia. Aminoff M, Daroff R, eds., Encyclopedia of Neurological Sciences. 2003; 4:465-469.
  124. Howard MW, Rizzuto DS ,Caplan JB, Madsen JR, Lisman J. Aschenbrenner-Scheibe R, Schulze-Bonhage A, Kahana MJ. Gamma oscillations increase with working memory load in humans. Cerebral Cortex. 2003; 13(12):1369-74.
  125. Glader LJ, Elias ER, Madsen JR. Neonatal hydrocephalus. Hansen AR, Puder M, eds., Manual of Neonatal Surgical Intensive Care. 2003; 394-405.
  126. Smith JS, Madsen JR. Surgical treatment of pain in the child. Schechter NL, Berde CB, Yaster M, eds., Pain Management in Infants, Children and Adolescents. 2003; 329-339.
  127. Tzika AA, Cheng LL, Goumnerova L, Madsen JR, Zurakowski D, Astrakas LG, Zarifi MK, Scott RM, Anthony DC, Gonzalez RG, Black PM. Biochemical characterization of pediatric brain tumors by using in vivo and ex vivo magnetic resonance spectroscopy. J Neurosurg. 2002 Jun; 96(6):1023-31.
  128. Joseph R. Madsen. Variable anti-siphon valve apparatus and method. 2002.
  129. Greenes DS, Madsen JR. Neurotrauma. Fleisher GR, Ludwig S, eds., Synopsis of Pediatric Emergency Medicine, Revised Edition. 2002; 474-486.
  130. Madsen JR, Poussaint TY, Barnes PD. Congenital malformations of the cerebellum and posterior fossa. Manto M-U, Pandolfo M, eds, The Cerebellum and Its Disorders. 2002; 161-177.
  131. Kahana MJ, Seelig D, Madsen JR. Theta returns. Curr Opin Neurobiol. 2001 Dec; 11(6):739-44.
  132. Valencia I, Holder DL, Helmers SL, Madsen JR, Riviello JJ. Vagus nerve stimulation in pediatric epilepsy: a review. Pediatr Neurol. 2001 Nov; 25(5):368-76.
  133. Helmers SL, Wheless JW, Frost M, Gates J, Levisohn P, Tardo C, Conry JA, Yalnizoglu D, Madsen JR. Vagus nerve stimulation therapy in pediatric patients with refractory epilepsy: retrospective study. J Child Neurol. 2001 Nov; 16(11):843-8.
  134. Joseph R. Madsen and George A. Taylor. Non-invasive in vivo pressure measurement. 2001.
  135. Logigian EL, Soriano SG, Herrmann DN, Madsen JR. Gentle dorsal root retraction and dissection can cause areflexia: implications for intraoperative monitoring during "selective" partial dorsal rhizotomy. Muscle Nerve. 2001 Oct; 24(10):1352-8.
  136. Sotero de Menezes MA, Connolly M, Bolanos A, Madsen J, Black PM, Riviello JJ. Temporal lobectomy in early childhood: the need for long-term follow-up. J Child Neurol. 2001 Aug; 16(8):585-90.
  137. Caplan JB, Madsen JR, Raghavachari S, Kahana MJ. Distinct patterns of brain oscillations underlie two basic parameters of human maze learning. J Neurophysiol. 2001 Jul; 86(1):368-80.
  138. Raghavachari S, Kahana MJ, Rizzuto DS, Caplan JB, Kirschen MP, Bourgeois B, Madsen JR, Lisman JE. Gating of human theta oscillations by a working memory task. J Neurosci. 2001 May 1; 21(9):3175-83.
  139. Madsen JR . Shunt Malfunction. In: Gilman S ed. Medlink Neurology. (electronic media). 2001.
  140. Madsen JR, Campbell J . Corpus callosotomy. Albright AL, Pollack IF, Adelson PD, eds., Atlas of Operative Techniques in Pediatric Neurosurgery. 2001; 257-265.
  141. Madsen JR. Prenatal diagnosis and counseling for the neurosurgeon. McLone DG, ed., Pediatric Neurosurgery. 2001; 332-341.
  142. Valencia I, Holder DL, Helmers SL, Madsen JR, Riviello JJ. Vagus nerve stimulation in pediatric epilepsy: A review. Pediatric Neurol. 2001; 25:368-76.
  143. Madsen JR. Long-term vagus nerve stimulation beneficial in refractory epilepsy. Journal Watch Neurology. 2000; 2:3.
  144. Joseph R. Madsen. Subdural electrode arrays for monitoring cortical electrical activity. 2000.
  145. Joseph R. Madsen and George A. Taylor. Non-invasive in vivo pressure measurement. 2000.
  146. Madsen JR. [Chronic inflammatory bowel disease--pathogenic concepts and therapeutic perspectives]. Ugeskr Laeger. 2000 Mar 6; 162(10):1361-6.
  147. Gilmartin R, Bruce D, Storrs BB, Abbott R, Krach L, Ward J, Bloom K, Brooks WH, Johnson DL, Madsen JR, McLaughlin JF, Nadell J. Intrathecal baclofen for management of spastic cerebral palsy: multicenter trial. J Child Neurol. 2000 Feb; 15(2):71-7.
  148. Lee IW, Vacanti JP, Taylor GA, Madsen JR. The living shunt: a tissue engineering approach in the treatment of hydrocephalus. Neurol Res. 2000 Jan; 22(1):105-10.
  149. Soriano SG, Eldredge EA, Wang FK, Kull L, Madsen JR, Black PM, Riviello JJ, Rockoff MA. The effect of propofol on intraoperative electrocorticography and cortical stimulation during awake craniotomies in children. Paediatr Anaesth. 2000; 10(1):29-34.
  150. Manning SM, Jennings R, Madsen JR. Pathophysiology, prevention, and potential treatment of neural tube defects. Ment Retard Dev Disabil Res Rev. 2000; 6(1):6-14.
  151. Manning S, Jennings R, Madsen JR. Pathology, Prevention, and Potential Treatment of Neural Tube Defects. Mental Retardation and Develop Disabil Res Rev. 2000; 6:6-14.
  152. Raghavachari S, Kahana MJ, Rizzuto DS, Caplan JB, Kirschen M, Madsen JR, Lisman JE. Human Theta Oscillations are Gated by a Working Memory Task. Soc. for Neurosci. Abst. 2000; 26(2):1589.
  153. Caplan JB, Kahana MJ, Raghavachari S, Madsen JR. Human Theta Oscillations During Virtual Maze Navigation. Soc. for Neurosci. Abst. 2000; 26(2):1589.
  154. Madsen JR, Penn RD. Procedures for intrathecal pharmacological therapy. Kaye AH, Black PMcL, eds., Operative Neurosurgery. 2000; 1505-1512.
  155. Kahana MJ, Lisman J, Madsen JR. Theta Oscillations, memory and epilepsy. Soc. Neurosci. Abstr. 2000; 26(1):810.
  156. Greenes DS, Madsen JR . Neurotrauma. Fleisher GR, Ludwig S, eds., Textbook of Pediatric Emergency Medicine. 2000; 1271-1296.
  157. Madsen JR, Karluk D. Case Records of the Massachusetts General Hospital. Case 34-2000: a 71-year-old woman with an enlarging pituitary mass. New Engl J Med. 2000; 343:1399-1407.
  158. Madsen JR, Helmers SL. Treatment of intractable epilepsy by electrical stimulation of the vagus nerve. Schmidek HH, ed., Operative Neurosurgical Techniques. 2000; 1421-1428.
  159. Caplan JB, Kahana MJ, Sekuler R, Kirschen M, Madsen JR. Task dependence of human theta: the case for multiple cognitive functions. Neurocomputing. 2000; 32-33:659-665.
  160. Levine D, Barnes PD, Madsen JR, Abbott J, Mehta T, Edelman RR. Central nervous system abnormalities assessed with prenatal magnetic resonance imaging. Obstet Gynecol. 1999 Dec; 94(6):1011-9.
  161. Benowitz LI, Goldberg DE, Madsen JR, Soni D, Irwin N. Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury. Proc Natl Acad Sci U S A. 1999 Nov 9; 96(23):13486-90.
  162. Kahana MJ, Caplan JB, Sekuler R, Madsen JR. Using intracranial recordings to study thetaResponse to J. O'Keefe and N. Burgess (1999). Trends Cogn Sci. 1999 Nov; 3(11):406-407.
  163. Khurana DS, Strawsburg RH, Robertson RL, Madsen JR, Helmers SL. MRI signal changes in the white matter after corpus callosotomy. Pediatr Neurol. 1999 Oct; 21(4):691-5.
  164. Madsen JR . Seizure outcome after surgery in very young children. Journal Watch Neurology. 1999; 1:3.
  165. Kahana MJ, Sekuler R, Caplan JB, Kirschen M, Madsen JR. Human theta oscillations exhibit task dependence during virtual maze navigation. Nature. 1999 Jun 24; 399(6738):781-4.
  166. Levine D, Barnes PD, Madsen JR, Abbott J, Wong GP, Hulka C, Mehta T, Li W, Edelman RR. Fetal CNS anomalies revealed on ultrafast MR imaging. AJR Am J Roentgenol. 1999 Mar; 172(3):813-8.
  167. Madsen JR, Partington MD, Hay TC, Tyson RW. A 2-month-old female infant with progressive macrocephaly and irritability -clinical conference-. Pediatr Neurosurg. 1999 Mar; 30(3):157-63.
  168. Kahana MJ, Caplan JB, Sekuler R, Madsen JR. Using intracranial recordings to study theta: Response to J. O’Keefe and N. Burgess. Trends Cognit Sci. 1999; 3:406-407.
  169. Madsen JR, Helmers S. Vagal Nerve Stimulation for Treatment of Epilepsy in Pediatric Patients. 1999.
  170. Madsen JR, Black PM. Corpus callosotomy in children. Albright AL, Pollack IF, Adelson PD, eds., Principles and Practice in Pediatric Neurosurgery. 1999; 1147-1156.
  171. Madsen JR, Frim DM. Neurosurgery of the Newborn. Avery GB, Fletcher MA, McDonald MG, eds., Neonatology: Pathophysiology and Management of the Newborn. 1999; 1231-1252.
  172. Yalnizoglu D, Helmers S, Madsen JR. Vagal Nerve Stimulation In Children With Medically Intractable Epilepsy Following Epilepsy Surgery. American Epilepsy Society Annual Meeting abstract. 1999.
  173. Madsen JR, Kirschen M, Caplan JB, Sekuler R, Kahana MJ. Task-related Theta Activity from Intracranial Recordings During Virtual Maze Navigation - Oral Presentation. 1999.
  174. Madsen JR, Kirschen M, Caplan JB, Sekuler R, Kahana MJ. Task-related Theta Activity from Intracranial Recordings During Virtual Maze Navigation. 1999.
  175. Caplan JB, Kahana MJ, Sekuler R, Kirschen M, Madsen JR. The Role of Theta Oscillations in Human Spatial Cognition: Evidence from Intracranial Recordings. 1999.
  176. Raghavachari S, Caplan JB, Kirschen M, Kahana MJ, Madsen JR, Lisman JE. The Sternberg Task Evokes Theta Oscillations in Human Intracranial Recordings. 1999.
  177. Madsen JR, Helmers S. Vagal nerve stimulation in children with intractable epilepsy—results in five centers - Poster Presentation. 1999.
  178. Madsen JR, Helmers S. Vagal Nerve Stimulation for Treatment of Epilepsy in Pediatric Patients. 1999.
  179. Madsen JR. Craniotomy of Unusual Interest: Issues for Medicine, Law, Journalism, and Society in a Highly Publicized Case of Nonaccidental Trauma. 1999.
  180. Madsen JR, Goldberg D, Riviello J. Intracranial Pressure during Seizures in Children - Poster Presentation. 1999.
  181. Madsen JR, MacDonald P, Irwin N, Goldberg DE, Yao GL, Meiri KF, Rimm IJ, Stieg PE, Benowitz LI. Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. Exp Neurol. 1998 Dec; 154(2):673-83.
  182. Maxwell M, Allegra C, MacGillivray J, Hsu DW, Hedley-Whyte ET, Riskind P, Madsen JR, Black PM. Functional transplantation of the rat pituitary gland. Neurosurgery. 1998 Nov; 43(5):1157-63.
  183. Madsen JR, Vallat AV, Poussaint TY, Scott RM, De Girolami U, Anthony DC. Focal cortical dysplasia with glioproliferative changes causing seizures: report of 3 cases. Pediatr Neurosurg. 1998 May; 28(5):261-6.
  184. Munshi I, Lathrop D, Madsen JR, Frim DM. Intraventricular pressure dynamics in patients with ventriculopleural shunts: a telemetric study. Pediatr Neurosurg. 1998 Feb; 28(2):67-9.
  185. Madsen JR, Robertson RL, Bartlett R. Surgical management of cutis aplasia with high-flow sinus pericranii. Pediatr Neurosurg. 1998 Feb; 28(2):79-83.
  186. Lin T, Brunner T, Tietz B, Madsen J, Bonfoco E, Reaves M, Huflejt M, Green DR. Fas ligand- mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease. J Clin Invest. 1998 Feb 1; 101(3):570-7.
  187. Frim DM, Scott RM, Madsen JR. Surgical management of neonatal hydrocephalus. Neurosurg Clin N Am. 1998 Jan; 9(1):105-10.
  188. Madsen JR, Estroff J, Levine D. Prenatal neurosurgical diagnosis and counseling. Neurosurg Clin N Am. 1998 Jan; 9(1):49-61.
  189. Madsen JR, Estroff J, Levine D. Antenatal diagnosis and counseling in neurosurgical anomalies. Neurosurgical Clin N America. 1998; 9:49-61.
  190. Madsen JR, Freiman T. Cervical spinal cord injury in children. Contemp Neurosurg. 1998; 20(26):1-4.
  191. Madsen JR, MacDonald P, Irwin N, Yao GL, Rimm IJ, Stieg PE, Benowitz L. Tacrolimus (FK-506) increases neuronal expression of GAP-43 and improves neurological outcome after spinal cord injury in rats. Exper Neurol. 1998; 154:673-683.
  192. Madsen JR. Syringomyelia. Adelman G, Smith BH, eds. Encylcopedia of Neuroscience . 1998.
  193. Park JK, Frim DM, Schwartz MS, Reidy P, Farley JA, Black PM, Scott RM, Goumnerova LC, Madsen JR. The use of clinical practice guidelines (CPGs) to evaluate practice and control costs in ventriculoperitoneal shunt management. Surg Neurol. 1997 Dec; 48(6):536-41.
  194. Jackson PS, Madsen JR. Cerebral edema, cell volume regulation, and the role of ion channels in organic osmolyte transport. Pediatr Neurosurg. 1997 Dec; 27(6):279-85.
  195. Jackson PS, Madsen JR. Identification of the volume-sensitive organic osmolyte/anion channel in human glial cells. Pediatr Neurosurg. 1997 Dec; 27(6):286-91.
  196. Magge S, Madsen JR. Molecular biology of axonal outgrowth. 2. Pathfinding and molecular guidance cues. Pediatr Neurosurg. 1997 Oct; 27(4):168-75.
  197. Hansen AR, Volpe JJ, Goumnerova LC, Madsen JR. Intraventricular urokinase for the treatment of posthemorrhagic hydrocephalus. Pediatr Neurol. 1997 Oct; 17(3):213-7.
  198. Medlock MD, Madsen JR, Barnes PD, Anthony DS, Cohen LE, Scott RM. Optic chiasm astrocytomas of childhood. 1. Long-term follow-up. Pediatr Neurosurg. 1997 Sep; 27(3):121-8.
  199. Lim C, Blume HW, Madsen JR, Saper CB. Connections of the hippocampal formation in humans: I. The mossy fiber pathway. J Comp Neurol. 1997 Sep 1; 385(3):325-51.
  200. Levine D, Barnes PD, Madsen JR, Li W, Edelman RR. Fetal central nervous system anomalies: MR imaging augments sonographic diagnosis. Radiology. 1997 Sep; 204(3):635-42.
  201. Irwin N, Madsen JR. Molecular biology of axonal outgrowth. 1. Growth cones and GAP-43. Pediatr Neurosurg. 1997 Sep; 27(3):113-20.
  202. Lim C, Mufson EJ, Kordower JH, Blume HW, Madsen JR, Saper CB. Connections of the hippocampal formation in humans: II. The endfolial fiber pathway. J Comp Neurol. 1997 Sep 1; 385(3):352-71.
  203. Park JK, Gleason PL, Madsen JR, Goumnerova LC, Scott RM. Presentation and management of Chiari I malformation in children. Pediatr Neurosurg. 1997 Apr; 26(4):190-6.
  204. Malek AM, Weller SJ, Price DL, Madsen JR. Solitary fibrous tumor presenting as a symptomatic intraspinal mass: case report. Neurosurgery. 1997 Apr; 40(4):844-7; discussion 847.
  205. Kramer U, Riviello JJ, Carmant L, Black PM, Madsen J, Holmes GL. Clinical characteristics of complex partial seizures: a temporal versus a frontal lobe onset. Seizure. 1997 Feb; 6(1):57-61.
  206. Hansen AR, Volpe JJ, Goumnerova LC, Madsen JR. Intraventricular urokinase for the treatment of posthemorrhagic hydrocephalus: Fibrinolytic state does not preclude need for CSF shunt. Pediatric Neurology. 1997; 17:213-217.
  207. Madsen JR . Neck Pain [book review]. J Bone Joint Surgery. 1997; 79A:317.
  208. Madsen JR, Troup C, Goumnerova L. Miscellaneous benign tumors. Black PMcL, Loeffler JS,. eds., Tumors of the Central Nervous System. 1997; 431-440.
  209. Tacrolimus (FK506) increases neuronal expression of GAP-43 as it improves neurological recovery after spinal cord injury in rats - Oral Presentation. 1997.
  210. Lee I, Vacanti JP, Yoo J, Madsen JR. A tissue engineering approach for dural and cranial grafts - Oral Presentation. 1997.
  211. Madsen JR, Goumnerova L, Volpe J, Hansen A. Intraventricular urokinase for the treatment of posthemorrhagic hydrocephalus. 1997.
  212. Madsen JR. The future of epilepsy surgery for children. Harvard Mahoney Neuroscience Institute Letter. 1997; 6(2):1-7.
  213. Taylor GA, Madsen JR. Neonatal hydrocephalus: hemodynamic response to fontanelle compression-- correlation with intracranial pressure and need for shunt placement. Radiology. 1996 Dec; 201(3):685-9.
  214. Matsuo F, Gay P, Madsen J, Tolman KG, Rollins DE, Risner ME, Lai AA. Lamotrigine high-dose tolerability and safety in patients with epilepsy: a double-blind, placebo-controlled, eleven-week study. Epilepsia. 1996 Sep; 37(9):857-62.
  215. Logigian EL, Shefner JM, Goumnerova L, Scott RM, Soriano SG, Madsen J. The critical importance of stimulus intensity in intraoperative monitoring for partial dorsal rhizotomy. Muscle Nerve. 1996 Apr; 19(4):415-22.
  216. FK-506 Improvement in Recovery after Spinal Cord Injury: Possible Role of GAP-43 Expression and Calcineurin Effect. 1996.
  217. Madsen JR. After neurotrauma: brain and spinal cord repair. Harvard Mahoney Neuroscience Institute Letter. 1996; 5(2):1-7.
  218. Madsen JR, MacDonald P, Sankappanavar GH, Benowitz LI. FK-506 improves recovery after spinal cord injury: immunophilins as a new therapeutic target. Soc. Neurosci. Abstr. 1996; 22(1):264.
  219. FK-506 Improves Neurological Outcome and Increases Neuronal Expression of GAP-43 after Spinal Cord Injury in Rats. 1996.
  220. Madsen JR, Taylor G . Hemodynamic Response to Fontanelle Compression in Neonatal Hydrocephalus: Correlation with intracranial pressure and need for shunt placement - Radiology. 1996.
  221. Madsen JR, MacDonald P, Benowitz L. FK-506 improvement in recovery after spinal cord injury: possible role of GAP-43 expression in calcineurin effect. Research Society of Neurological Surgeons meeting abstract. 1996.
  222. Black PMcL, Madsen JR, Barnes PA . Congenital Malformations of the Cerebrum. In Tindall GT, Copper PR, Barrow DL., eds. The Practice of Neurosurgery. 1996; 3:2625-2634.
  223. Madsen JR, Goumnerova L, Hansen A. Intraventricular urokinase for the treatment of posthemorrhagic hydrocephalus - abstract. 1996.
  224. Estroff JA, Parad RB, Barnes PD, Madsen JP, Benacerraf BR. Posterior fossa arachnoid cyst: an in utero mimicker of Dandy-Walker malformation. J Ultrasound Med. 1995 Oct; 14(10):787-90.
  225. Madsen JR, Adelson PD, Haglund MM. The future of pediatric epilepsy surgery. Signposts and science. Neurosurg Clin N Am. 1995 Jul; 6(3):589-97.
  226. Madsen JR, Carmant L, Holmes GL, Black PM. Corpus callosotomy in children. Neurosurg Clin N Am. 1995 Jul; 6(3):541-8.
  227. Yasutomi Y, Koenig S, Woods RM, Madsen J, Wassef NM, Alving CR, Klein HJ, Nolan TE, Boots LJ, Kessler JA, et al. A vaccine-elicited, single viral epitope-specific cytotoxic T lymphocyte response does not protect against intravenous, cell-free simian immunodeficiency virus challenge. J Virol. 1995 Apr; 69(4):2279-84.
  228. Carmant L, Kramer U, Riviello JJ, Helmers SL, Mikati MA, Madsen JR, Black PM, Lombroso CT, Holmes GL. EEG prior to hemispherectomy: correlation with outcome and pathology. Electroencephalogr Clin Neurophysiol. 1995 Apr; 94(4):265-70.
  229. Soriano SG, Logigian EL, Scott RM, Prahl PA, Madsen JR. Nitrous oxide depresses the H-reflex in children with cerebral palsy. Anesth Analg. 1995 Feb; 80(2):239-41.
  230. Adelson PD, Black PM, Madsen JR, Kramer U, Rockoff MA, Riviello JJ, Helmers SL, Mikati M, Holmes GL. Use of subdural grids and strip electrodes to identify a seizure focus in children. Pediatr Neurosurg. 1995; 22(4):174-80.
  231. Logigian E, Shefner J, Goumnerova L, Prahl P, Madsen JR. The critical importance of stimulus intensity in intraoperative monitoring for selective dorsal rhizotomy (DR). American Society of Electrophysiology abstract. 1995.
  232. Madsen JR, Scott RM, Logigian EL. The latency test: criterion for valid reflexes in dorsal rhizotomy surgery. American Society of Pediatric Neurosurgeons abstract. 1995.
  233. Medlock MD, Madsen JR, Tarbell NJ, Barnes PD, Anthony DS, Scott RM. The role of surgery in the management of optic chiasm astrocytomas in childhood. American Association of Neurological Surgeons abstract. 1995.
  234. Carmant L, O'Tuama LA, Roach PJ, Kramer U, Mikati MA, Riviello JJ, Helmers SL, Madsen JR, Black PM, Lombroso CT, et al. Technetium-99m HmPAO brain SPECT and outcome of hemispherectomy for intractable seizures. Pediatr Neurol. 1994 Oct; 11(3):203-7.
  235. Logigian EL, Wolinsky JS, Soriano SG, Madsen JR, Scott RM. H reflex studies in cerebral palsy patients undergoing partial dorsal rhizotomy. Muscle Nerve. 1994 May; 17(5):539-49.
  236. Madsen JR, Weisfeiler O, Greenspan A, Benowitz LI. Conditioned media from a transformed glial-like cell line enhances neurite outgrowth and GAP-43 expression. Soc. Neurosci. Abstr. 1994; 20(2):1687.
  237. Jackson PS, Strange K, Madsen JR. Identification of volume-sensitive organic osmolyte channels in human glial cells. Soc. Neurosci. Abstr. 1994; 20(2):1502.
  238. Soriano SG, Logigian EL, Prahl PA, Madsen JR, Scott RM. Nitrous oxide depresses the H-reflex in children with cerebral palsy. American Society for Anesthesiology Meeting abstract. 1994.
  239. Sathi S, Madsen JR, Bauer S, Scott RM. Effect of surgical repair on the neurologic function in infants with lipomeningocele. Pediatr Neurosurg. 1993 Sep-Oct; 19(5):256-9.
  240. Madsen JR, Scott RM. Chiari malformations, syringomyelia, and intramedullary spinal cord tumors. Curr Opin Neurol Neurosurg. 1993 Aug; 6(4):559-63.
  241. O'Tuama LA, Treves ST, Larar JN, Packard AB, Kwan AJ, Barnes PD, Scott RM, Black PM, Madsen JR, Goumnerova LC, et al. Thallium-201 versus technetium-99m-MIBI SPECT in evaluation of childhood brain tumors: a within-subject comparison. J Nucl Med. 1993 Jul; 34(7):1045-51.
  242. Carmant L, Riviello J, Kramer U, Helmers S, Mikati M, Madsen JR, Black PMcL, Holmes GL. EEG patterns in patients undergoing hemispherectomy evaluation. 1993.
  243. Carmant L, Riviello J, Kramer U, Helmers S, Mikati M, Madsen JR, Black PMcL, Holmes GL. SPECT scan findings in the evaluation of hemispherectomy for intractable seizures: A predictor of favorable outcome. 1993.
  244. Madsen JR, Weisfeiler O, Benowitz LI. Neurite outgrowth and GAP-43 expression: effects of glial substrate and of monoclonal antibodies recognizing glial cell surface proteins. Soc. Neurosci. Abstr. 1993; 19(1):626.
  245. Goumnerova LC, Sathi S, Scott RM, Madsen JR. Treatment of medulloblastoma with pre-irradiation chemotherapy: experience at Boston Children’s Hospital from 1984 to 1991 - Pediatric Session. 1993.
  246. Carmant L, O’Tuama LA, Treves S, Kramer U, Holmes GL, Riviello JJ, Helmers SL, Black PMcL, Madsen JR, Mikati M. HMPAO SPECT versus outcomes of hemispherectomy for intractable seizures. Child Neurology Society Meeting abstract. 1993.
  247. Madsen JR. Astrocytomas of the cerebellum. Black PMcL, Schoene WC, Lampson LA, eds. Astrocytomas: Diagnosis, Treatment, and Biology. 1993; 175-180.
  248. Madsen JR. Epilepsy surgery, ed by HO Luders [book review]. J Epilepsy. 1993; 6:131.
  249. Carmant L, Riviello J, Kramer U, Helmers S, Mikati M, Madsen JR, Black P, Holmes G. EEG Patterns in patients undergoing hemispherectomy correlation with outcome and pathology. Epilepsia. 1993.
  250. O’Tuoma LA, Treves ST, Larar JN, Packard AB, Kwan AJ, Barnes PD, Scott RM, Black PMcL, Madsen JR, Goumnerova LC, Sallan SE, Tarbell NJ. 201Tl versus 99mTc-MIBI SPECT in evaluation of childhood brain tumors: a within-subject comparison. J Nucl Med. 1993; 34:1045-1051.
  251. Mikati M, Kramer U, Carmant L, Helmers S, Riviello J, Holmes G, Madsen J, Black P. Discharge morphology and propagation patterns in temporal lobe epilepsy in children and adolescents: effects of age. American Epilepsy Society Meeting abstract. 1993.
  252. Rossitch E Jr, Madsen JR. Neurosurgical procedures for the relief of pain in children and adolescents. Schechter NL, Berde CB, Yaster M, eds. Pain Management in Infants, Children and Adolescents. 1993; 237-243.
  253. Madsen JR, Scott RM, Goumnerova LC, Wolinsky JS, Logigian EL. The latency test: distinguishing valid reflexes in dorsal rhizotomy surgery - Pediatric SEssion. 1993.
  254. Madsen JR . Immunological approach to putative glial surface molecules affecting neurite outgrowth: changes with normal development and after lesions - Poster Session. 1992.
  255. Sathi S, Folkerth R, Madsen JR. Cavernous angioma of the posterior fossa dura mimicking a meningioma: case report and review of literature. Surg Neurol. 1992 Oct; 38(4):257-60.
  256. Kim YC, Black PMcL, Madsen J, Holmes GL . Comparison of surface and intracranial electrode studies in children with temporal lobe seizures. American Epilepsy Society Meeting abstract. 1992.
  257. Madsen JR. Glial surface molecules affecting neurite outgrowth: immunological dissection using monoclonal antibodies - Poster Session. 1992.
  258. Madsen JR. Glial surface molecules in lesions and regeneration: generation of a panel of monoclonal antibodies. Soc. Neurosci. Abstr. 1992; 18(2):1448.
  259. Madsen JR, Rosenberg A. Case records of the Massachusetts General Hospital, case 16-1992: a 27-year-old woman with pain in the neck and shoulder. N Engl J Med. 1992; 326:1070-1076.
  260. Black PM, Madsen J. Chronic increased intracranial pressure. Asbury AK, McKhann GM, McDonald WI, eds. Diseases of the Nervous System. 1992; 967-977.
  261. Madsen JR. Spinal tumors in children and adolescents, ed by I Pascual-Castroviejo. [book review]. Surg Neurol. 1991; 36:73-74.
  262. Madsen JR, Reidy P. The pediatric neurosurgical patient: a cooperative approach, ed. by LP Ivan. [book review]. J Neurosurg. 1991; 74:306-307.
  263. Madsen JR. Glial surface molecules affecting neurite outgrowth: immunological dissection using monoclonal antibodies - Open Scientific Session. 1991.
  264. Astrup A, Toubro S, Cannon S, Hein P, Breum L, Madsen J. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am J Clin Nutr. 1990 May; 51(5):759-67.
  265. Madsen JR, Matthew WD . Immunoreactivity for two promotors of neurite outgrowth in pituitary cell subsets - Poster Session,. 1990.
  266. Pearl PL, Carrazana EJ, Holmes GL, Russman BS, Madsen, JR. Psychosis and aggressive behavior after corpus callosotomy - Poster Presentation. 1990.
  267. Madsen JR, Heros RC. Giant peripheral aneurysms of the posterior inferior cerebellar artery presenting as cerebellar masses. Sugita K, Shibuya M, eds. Intracranial Aneurysms and Arteriovenous Malformations: State of the Art. 1990; 277-282.
  268. Madsen JR, Heros RC. Giant peripheral aneurysms of the posterior inferior cerebellar artery presenting as cerebellar masses. 1989.
  269. De la Monte SM, Madsen JR. X Hapten immunoreactivity in oligodendrogliomas. Lab Invest; 60:23A. 1989.
  270. Ballantine HT, Madsen R. An interview with Dr. HT Ballantine - video presentation. 1989.
  271. Madsen JR, Matthew WD. Immunoreactivity in pituitary gonadotropes and hypothalamic vasopressinergic neurons for the monoclonal antibody INO. J Neuroimmunol. 1988 Nov; 20(1):83-91.
  272. Madsen JR, Heros RC. Giant peripheral aneurysm of the posterior inferior cerebellar artery treated with excision and end-to-end anastomosis. Surg Neurol. 1988 Aug; 30(2):140-3.
  273. Madsen JR, Hsu DW, Hedley-Whyte ET, Matthew WD. Expression of X hapten immunoreactivity by human and rat adenohypophyseal cells. J Neurosurg. 1988 Jun; 68(6):938-46.
  274. Madsen JR, Heros RC. Spinal arteriovenous malformations and neurogenic claudication. Report of two cases. J Neurosurg. 1988 May; 68(5):793-7.
  275. Schmidek HH, Madsen JR. . Commentary on the transvenous treatment of antero-inferior dural venous fistulae. Schmidek HH, Sweet WH, eds. Operative Neurosurgical Techniques: Indications, Methods and Results. 1988; 849-854.
  276. Madsen JR, Heros RC. Spinal arteriovenous malformations and spinal claudication: a diagnostic dilemma. 1988.
  277. Heros RC, Madsen JR. 1988.
  278. Frim, DM, Madsen JR, eds. . Neurosurgery of the Neonate. Neurosurgical Clinics of North America. 1988.
  279. Maxwell M, MacGillivary J, Allegra C, Madsen JR, Black PMcL . Transplantation of neonatal rat pituicytes into the third ventricle of hypophysectomized recipients leads to restitution of plasma adenohypophyseal hormone levels. 1987.
  280. Madsen JR, Hedley-Whyte ET. Immunohistochemistry of pituitary adenomas. Neurology Neurosurgery Update Series. 1987; 7(24):1-8.
  281. Madsen JR, Hsu DW, Hedley-Whyte ET, Matthew WD. Expression of X-hapten immunoreactivity by human and rat adenohypophyseal cells: alterations in tumors and estrogen-induced hyperplasia. 1987.
  282. Madsen JR, Matthew WD. Immunologically defined astrocyte subsets: implications for axonal regeneration after central nervous system injury. Surgical Forum. 1987; 37:512-515.
  283. Madsen JR. Neuromethods, volumes 1 and 2 [book review]. Am J Neuroradiology. 1987; 8:608.
  284. Heros RC, Madsen JR. Hemodynamic method to predict whether Hunterian ligation of the basilar artery will lead to thrombosis of basilar bifurcation aneurysms: Comment. Neurosurgery. 1987; 20:252-253.
  285. Maxwell M, MacGillivary J, Allegra C, Madsen JR, Black PMcL. Functional transplantation of the pituitary gland - Open Scientific Session. 1987.
  286. Hamilton AJ, Black PM, Madsen J, Carr DB. Neuropeptide investigations with an ovine surgical model. Neurosurgery. 1986 Jun; 18(6):748-55.
  287. Madsen JR, Sandrock AW, Matthew WD. Re-expression of an antigen present in developing CNS by injured and sprouting adult neurons - Open Scientific Session. 1986.
  288. Madsen JR, Black PM, Flynn S, Royal HD. Cerebrospinal fluid anion transport: studies of pertechnetate in unanesthetized sheep. Neurosurgery. 1985 Nov; 17(5):778-83.
  289. Madsen JR, Black PMcL, Royal HD. Pertechnetate as a probe of the anion clearance mechanisms of the brain - Poster Session. 1984.
  290. Campbell A, Herschel M, Sommer B, Madsen JR, Cohen BM, Baldessarini RJ. Circadian changes in the destruction and effects of haloperidol in the rat. Neuropharmacology. 1982 Jul; 21(7):663-9.
  291. Baldessarini RJ, Campbell A, Madsen J, Herschel M, Finkelstein S, Smith JM, Majocha R, Arana G. Chronopsychopharmacology. Psychopharm Bull. 1982; 17:112-113.
  292. Madsen JR, Campbell A, Baldessarini RJ. Effects of prenatal treatment of rats with haloperidol due to altered drug distribution in neonatal brain. Neuropharmacology. 1981 Oct; 20(10):931-9.
  293. Delgado-Escueta AV, Mattson RH, King L, Goldensohn ES, Spiegel H, Madsen J, Crandall P, Dreifuss F, Porter RJ. Special report. The nature of aggression during epileptic seizures. N Engl J Med. 1981 Sep 17; 305(12):711-6.
  294. Mandel MR, Madsen J, Miller AL, Baldessarini RJ. Intoxication associated with lithium and ECT. Am J Psychiatry. 1980 Sep; 137(9):1107-9.
  295. Campbell A, Herschel M, Madsen JR, Baldessarini RJ. Diurnal changes in effects of haloperidol in rats. Neurosci Abst. 1980; 6:707.
  296. Chiofalo N, Madsen J, Fuentes A, Basauri L, Castro M. Occlusive arterial disease of the child and young adult. Clinical electroencephalographical analysis of 26 cases. Childs Brain. 1978; 4(1):1-14.
  297. Stang PJ, Madsen JR, Mangum MG, Fox DP. Unsaturated carbenes from primary vinyl triflates: competitive addition of isopropylidene to olefins. J Org Chem. 1977; 42:1802-1804.
  298. MADSEN JR, ANDERSON GV. Lupus erythematosus and pregnancy. Obstet Gynecol. 1961 Oct; 18:492-4.
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