EDUCATION

Undergraduate Degree

  • University of Toronto , Toronto , Canada

Undergraduate Degree

  • McGill University , Montreal , Canada

Medical School

  • McGill University , Montreal , Canada

Residency

Pediatrics
  • Schneider Children's Hospital , New Hyde Park , NY

Fellowship

Pediatrics
  • Hospital for Sick Children , Toronto , Canada

CERTIFICATIONS

  • American Board of Pediatrics, Critical Care Medicine

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Hariton E, Matthews B, Burns A, Akileswaran C, Berkowitz LR. Pregnancy and parental leave among obstetrics and gynecology residents: results of a nationwide survey of program directors. Am J Obstet Gynecol. 2018 Aug; 219(2):199.e1-199.e8. View abstract
  2. Adini A, Adini I, Chi ZL, Derda R, Birsner AE, Matthews BD, D'Amato RJ. A novel strategy to enhance angiogenesis in vivo using the small VEGF-binding peptide PR1P. Angiogenesis. 2017 Aug; 20(3):399-408. View abstract
  3. Jurek SC, Hirano-Kobayashi M, Chiang H, Kohane DS, Matthews BD. Prevention of ventilator-induced lung edema by inhalation of nanoparticles releasing ruthenium red. Am J Respir Cell Mol Biol. 2014 Jun; 50(6):1107-17. View abstract
  4. Wang Y, Huang Z, Nayak PS, Matthews BD, Warburton D, Shi W, Sanchez-Esteban J. Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin a6ß1-ADAM17/tumor necrosis factor-a-converting enzyme (TACE) signaling pathway. J Biol Chem. 2013 Aug 30; 288(35):25646-57. View abstract
  5. Huh D, Leslie DC, Matthews BD, Fraser JP, Jurek S, Hamilton GA, Thorneloe KS, McAlexander MA, Ingber DE. A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Sci Transl Med. 2012 Nov 07; 4(159):159ra147. View abstract
  6. Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE. Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science. 2012 Aug 10; 337(6095):738-42. View abstract
  7. Greenberger S, Yuan S, Walsh LA, Boscolo E, Kang KT, Matthews B, Mulliken JB, Bischoff J. Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma. J Invest Dermatol. 2011 Dec; 131(12):2467-76. View abstract
  8. Matthews BD, Thodeti CK, Tytell JD, Mammoto A, Overby DR, Ingber DE. Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integr Biol (Camb). 2010 Sep; 2(9):435-42. View abstract
  9. Huh D, Matthews BD, Mammoto A, Montoya-Zavala M, Hsin HY, Ingber DE. Reconstituting organ-level lung functions on a chip. Science. 2010 Jun 25; 328(5986):1662-8. View abstract
  10. Matthews, B, Kohane, D, Ingber, D. Inhaled prophylactic nanotherapy for lung protection from Ventilator induced Lung Injury and Acute Respiratory Distress Syndrome (ARDS). 2010. View abstract
  11. Greenberger, S, Yuan, S, Walsh, L., Boscolo, E., Kang, K.T., Matthews, B, Mulliken, J.B., and Bischoff, J. . High-throughput Screen Identifies Rapamycin as a Drug to Suppress Self-Renewal and Vasculogenesis in Infantile Hemangioma. Journal of Cell Investigation (In Review). 2010. View abstract
  12. Matthews, B.D, Thodeti, C.K., Tytell, JD., Mammoto, A., Overby, D.R., and Ingber, D.E. . Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface β1 integrins. . Integrative Biology (In Review). 2010. View abstract
  13. Thodeti CK, Matthews B, Ravi A, Mammoto A, Ghosh K, Bracha AL, Ingber DE. TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res. 2009 May 08; 104(9):1123-30. View abstract
  14. Prodhan P, Dela Rosa RS, Shubina M, Haver KE, Matthews BD, Buck S, Kacmarek RM, Noviski NN. Wheeze detection in the pediatric intensive care unit: comparison among physician, nurses, respiratory therapists, and a computerized respiratory sound monitor. Respir Care. 2008 Oct; 53(10):1304-9. View abstract
  15. Stamenovic D, Rosenblatt N, Montoya-Zavala M, Matthews BD, Hu S, Suki B, Wang N, Ingber DE. Rheological behavior of living cells is timescale-dependent. Biophys J. 2007 Oct 15; 93(8):L39-41. View abstract
  16. Lele TP, Sero JE, Matthews BD, Kumar S, Xia S, Montoya-Zavala M, Polte T, Overby D, Wang N, Ingber DE. Tools to study cell mechanics and mechanotransduction. Methods Cell Biol. 2007; 83:443-72. View abstract
  17. Lele T, Sero J, Matthews BD, Kumar S, Xia S, Montoya-Zavala M, Polte T, Overby DR, Wang N and Ingber DE. . Tools to study cell mechanotransduction. In: Wang Y, Discher D., editors. Methods in Cell Biology. 2007; 441-472. View abstract
  18. Matthews BD, Thodeti CK and Ingber DE. . Integrin-dependent force transmission to mechanosensitive ion channels. In: Hammill O, editors. Mechanosensitive Ion Channels. 2007; 59-85. View abstract
  19. Dandapani SV, Sugimoto H, Matthews BD, Kolb RJ, Sinha S, Gerszten RE, Zhou J, Ingber DE, Kalluri R, Pollak MR. Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem. 2007 Jan 05; 282(1):467-77. View abstract
  20. Matthews BD, Overby DR, Mannix R, Ingber DE. Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci. 2006 Feb 01; 119(Pt 3):508-18. View abstract
  21. Alon R, Feigelson SW, Manevich E, Rose DM, Schmitz J, Overby DR, Winter E, Grabovsky V, Shinder V, Matthews BD, Sokolovsky-Eisenberg M, Ingber DE, Benoit M, Ginsberg MH. Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. J Cell Biol. 2005 Dec 19; 171(6):1073-84. View abstract
  22. Overby DR, Matthews BD, Alsberg E, Ingber DE. Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry. Acta Biomater. 2005 May; 1(3):295-303. View abstract
  23. Matthews BD, Overby DR, Alenghat FJ, Karavitis J, Numaguchi Y, Allen PG, Ingber DE. Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Biochem Biophys Res Commun. 2004 Jan 16; 313(3):758-64. View abstract
  24. Alkharouf NW, Matthews BF. SGMD: the Soybean Genomics and Microarray Database. Nucleic Acids Res. 2004 Jan 01; 32(Database issue):D398-400. View abstract
  25. Matthews, B. D., LaVan, D. A., Overby, D. R., Karavitis, J. and Ingber, D. E. . Electromagnetic needles with submicron pole tip radii for nanomanipulation of biomolecules and living cells. Applied Physics Letters. 2004; 85:2968-2970.. View abstract
  26. Matthews BD, Noviski N. Management of oxygenation in pediatric acute hypoxemic respiratory failure. Pediatr Pulmonol. 2001 Dec; 32(6):459-70. View abstract
  27. Tsakiridis T, Tong P, Matthews B, Tsiani E, Bilan PJ, Klip A, Downey GP. Role of the actin cytoskeleton in insulin action. Microsc Res Tech. 1999 Oct 15; 47(2):79-92. View abstract
  28. Oddos J, Grange T, Carr KD, Matthews B, Roux J, Richard-Foy H, Pictet R. Nucleotide sequence of 10 kilobases of rat tyrosine aminotransferase gene 5' flanking region. Nucleic Acids Res. 1989 Nov 11; 17(21):8877-8. View abstract