Steven J. Fishman, M.D. is Professor of Surgery at Harvard Medical School and the Stuart and Jane Weitzman Family Chair in Surgery at Boston Children’s Hospital. He obtained his B.S. and M.D. degrees at Northwestern University and completed his training in General Surgery at the University of Pennsylvania and in Pediatric Surgery at Boston Children’s Hospital. He is active in the practice and teaching of the broad spectrum of Pediatric Surgery, with particular clinical and research focus in the area of Vascular Anomalies. He is Co-Director of the Vascular Anomalies Center at Boston Children’s Hospital. This multidisciplinary group evaluates approximately 1700 patients annually with hemangiomas, rare vascular tumors and vascular malformations of all types. He is President of the International Society for the Study of Vascular Anomalies. Dr. Fishman created and hosts an international registry of hepatic hemangiomas. He has authored over 175 scientific publication and chapters and two books, including a recent comprehensive reference work on Vascular Anomalies with Drs. John Mulliken and Patricia Burrows. He is an Editorial Consultant for the Journal of Pediatric Surgery and on the Editorial Board of the Journal of Pediatric Surgery Case Reports. He has chaired the Publications Committee of the Surgical Section of the AAP. Dr. Fishman frequently serves as visiting professor and speaker nationally and internationally. In addition, he advises several patient/family-oriented support groups and frequently participates in their gatherings and clinics. At Boston Children’s, Dr. Fishman has served in many leadership roles, including as President of the Physician’s Organization, a member of the Board of Trustees and currently on the Hospital Executive Committee and as Vice-Chair of Surgery for Clinical Operations amongst innumerable committee responsibilities.
Dr. Fishman has a particular focus on developing an understanding and approach to visceral vascular anomalies. Though these anomalies are extremely rare, an international referral practice has facilitated the recognition of patterns in clinical presentation and opportunities for treatment. He has focused on developing evaluation and intervention techniques including innovative operative procedures for the treatment of visceral vascular anomalies. The utility of a modified endorectal pull-through technique for the treatment of colorectal venous malformations has been demonstrated. A surgical technique to eradicate gastrointestinal bleeding in the Blue Rubber Bleb Nevus Syndrome has been developed and proven successful. Dr. Fishman has extensive experience with resecting, debulking and reconstructing vascular malformations and associated overgrown tissues of the torso, genitalia, neck and extremities. In addition, the role of dynamic contrast lymphangiography of the thoracic duct has allowed for novel treatments and reconstruction of thoracic duct anomalies. Recognizing the limitations of surgical techniques, he is also focusing on understanding the biologic mechanisms involved in the development and progression of these lesions.
Another area of focus is in minimally invasive surgical techniques. As the first pediatric surgeon in Boston to perform minimally invasive procedures in infants and children, he has actively participated in the evolution of these techniques to the pediatric age group. Additionally, he has extensive experience in the treatment of gastrointestinal motility disorders. He introduced the use of botulinum toxin injection in the internal anal sphincter for refractory Hirschsprung’s disease and other anal sphincter motility disorders in Boston. In addition, he was one of the first to introduce the non-refluxing continent appendicocecostomy to this country. This has been very useful for the treatment of patients with fecal incontinence and constipation due to colorectal neuromotor abnormalities.
1. Mulliken JB, Fishman SJ, Burrows PE. (Eds.) Mulliken and Young’s Vascular Anomalies; Hemangiomas and Malformatiions, 2nd Ed., New York, Oxford University Press, 2013.
2. Cronenwett JL and Johnston KW. (Eds.) [Fishman SJ, section editor]. Rutherford’s Vascular Surgery, 8th Edition, Philadelphia, Saunders Elsevier, in press 2014.
3. Huang SA, Tu HM, Harney JW, Venihaki M, Butte AJ, Kozakewich HPW, Fishman SJ, Larsen PR. Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med 2000; 343(3): 185-89
4. Smink DS, Fishman SJ, Kleinman K, Finkelstein JA. The effects of race, insurance status and hospital volume on perforated appendicitis in children. Pediatrics 2005; 115(4): 920-25
5. Marler JJ, Fishman SJ, Kilroy SM, Fang J, Upton J, Mulliken JB, Burrows PE, Zurakowski D, Folkman J, Moses MA. Increased expression of urinary matrix metalloproteinases parallels the extent and progression of vascular anomalies. Pediatrics 2005; 116(1): 38-45
6. Yang EY, Allmendinger N, Johnson SM, Chen C, Wilson JM, Fishman SJ. Neonatal thoracoscopic repair of congenital diaphragmatic hernia: selection criteria for successful outcome. J Pediatr Surg 2005; 40(9): 1369-75
7. Barnes CM, Huang S, Kaipainen A, Sanoudou D, Chen EJ, Eichler GS, Guo Y, Yu Y, Ingber DE, Mulliken JB, Beggs AH, Folkman J, Fishman SJ. Evidence by molecular profiling for a placental origin of infantile hemangioma. Proc Natl Acad Sci USA 2005; 102: 19097-19102
8. Sena LM, Fishman SJ, Jenkins KJ, Xu H, Brechbiel MW, Regino CA, Kosaka N, Bernardo M, Choyke PL, Kobayashi H. Magnetic resonance lymphangiography with a nano-sized gadolinium-labeled dendrimer in small and large animal models. Nanomedicine 2010; 5(8): 1183-91
9. Greene AK, Liu AS, Mulliken JB, Chalache KN, Fishman SJ. Vascular anomalies in 5621 patients: guidelines for referral to a vascular anomalies center. J Pediatr Surg 2011; 46(9): 1784-9.
10. Fevurly RD, Hasso S, Fye A, Fishman SJ, Chan J. Novel zebrafish model reveals a critical role for MAPK in lymphangiogenesis. J Pediatr Surg 2012; 47(1): 177-82.
11. Kulungowski AM, Alomari AI, Chawla A, Christison-Lagay ER, Fishman SJ. Lessons from a liver hemangioma registry: subtype classification. J Pediatr Surg 2012; 47(1): 165-70.
12. Kurek KC, Luks VL, Ayturk UM, Alomari AI, Fishman SJ, Spencer SA, Mulliken JB, Bowen ME, Yamamoto GL, Kozakewich HP, Warman ML. Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am J Hum Genet 2012; 90(6): 1108-15.
13. Fishman SJ, Burrows PE, Leichtner AM, Mulliken JB. Gastrointestinal manifestations of vascular anomalies in childhood: varied etiologies require multiple therapeutic modalities. J Pediatr Surg 1998; 33(7): 1163-67
14. Fishman SJ, Feins NR, D’Amato RJ, Folkman J. Long-term remission of Crohn’s disease treated with Thalidomide: a seminal case report. Angiogenesis 1999; 3(3): 201-4
15. Fishman SJ, Shamberger RC, Fox VL, Burrows PE. Endorectal pull-through abates gastrointestinal hemorrhage from colorectal venous malformations. J Pediatr Surg 2000; 35(6): 982-84
16. Norwitz ER, Hoyte LPJ, Jenkins KJ, Van Der Velde ME, Ratiu P, Rodriguez-Thompson D, Wilkins-Haug L, Tempany CMC, Fishman SJ. Separation of conjoined twins with the twin-reversed-arterial-perfusion sequence after prenatal planning with three-dimensional modeling. N Engl J Med 2000; 343(6): 399-402
17. Fishman SJ, Burrows PE, Upton J, Hendren WH. Life-threatening anomalies of the thoracic duct: anatomic delineation dictates management. J Pediatr Surg 2001; 36(8): 1269-72
18. Fishman SJ, Smithers CJ, Folkman J, Lund DP, Burrows PE, Mulliken JB, Fox VL. Blue rubber bleb nevus syndrome: surgical eradication of gastrointestinal bleeding. Ann Surg 2005; 241(3): 523-28
19. Kim HB, Pomposelli JJ, Lillehei CW, Jenkins RL, Jonas MM, Krawczuk LE, Fishman SJ. Mesogonadal shunts for extrahepatic portal vein thrombosis and variceal hemorrhage. Liver Transpl 2005; 11: 1389-94
20. Vogel AM, Yang EY, Fishman SJ. Hydrostatic stretch-induced growth facilitating primary anastomosis in long-gap esophageal atresia. J Pediatr Surg 2006; 41(6): 1170-72
21. Christison-Lagay ER, Burrows PE, Alomari AI, Dubois J, Kozakewich HPW, Lane TS, Paltiel HJ, Klement G, Mulliken JB, Fishman SJ. Hepatic hemangiomas: sub-type classification and development of a clinical practice algorithm and registry. J Pediatr Surg 2007; 42(1): 62-68
22. Kulungowski AM, Fox VL, Burrows PE, Alomari AI, Fishman SJ. Portomesenteric venous thrombosis associated with rectal venous malformations. J Pediatr Surg 2010; 45(6): 1221-7
23. Siddiqui A, Fishman SJ, Bauer S, Nurko S. Long term follow up of patients after antegrade continence enema (ACE) procedure: a single center experience. J Pediatr Gastroent Nutr 2011; 52(5): 574-80
24. Kim HB, Vakili K, Modi BP, Ferguson MA, Guillot AP, Potanos KM, Prabhu SP, Fishman SJ. A novel treatment for the midaortic syndrome. N Eng J Med 2012; 367(24): 2361-2.