#1 Ranked Children’s Hospital by U.S. News & World Report
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Boston Children's has launched the world's 1st program dedicated to offering hand transplants to children who qualify.
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Here at the Heart Transplant Program, our treatment is informed by our research. Boston Children's Hospital is home to the world’s most extensive research enterprise at a pediatric hospital.
We also have the greatest level of partnerships with the top research, biotech and health care organizations in Boston, working together to improve kids’ health. Read on for examples of our science-driven care.
Clinical research by Boston Children's staff on the high waiting list mortality problem among children waiting for heart transplant led UNOS to establish a committee that will re-evaluate its heart allocation policy for children. It's anticipated that a new heart allocation policy, which will decrease waiting list mortality among children, will be implemented.
Sometimes, children waiting for donor hearts are so sick that they must be placed on life support mechanisms that keep them immobilized and unresponsive. But now there is the possibility of a better way.
For years Boston Children’s cardiologists and cardiovascular surgeons have researched, written about and implanted ventricular assist devices (VADs), which pump blood from the heart to the body and/or to the lungs. In 2007, Boston Children’s became one of the first hospitals to implant a Berlin Heart®—a mechanical device that temporarily takes over the heart’s pumping functions—in a child.
In 2013, our team became the first in America to send a child back to school with a new implantable VAD, called the HeartWare® device. Learn more.
Our Heart Transplant Program offers an immunosuppressant protocol that avoids the use of steroids. This means that your child could avoid the side effects commonly associated with steroids - including hypertension, diabetes and obesity – and enjoy a healthier post-transplant life.
Members of our research teams are also investigating the efficacy of the current system of heart organ allocation. Gaining a better understanding of the best process for optimal outcomes may lead to significant changes at the national level of heart allocation with more kids getting donor hearts more quickly.
We are currently one of six pediatric heart transplant centers participating in the Clinical Trials in Organ Transplantation in Children 04 study (CTOT-C04). The study looks at the effects of preformed antibodies against donor hearts on the immune system and on outcomes after heart transplant. The protocol allows us to consider transplantation for children with the highest levels of preformed antibodies by removing these antibodies at the time of transplantation. Boston Children’s Hospital serves as both a clinical site and a translational laboratory for this study.
Cardiologists here at Boston Children’s are working to develop innovative ways to ensure that hearts are rejection free. Kevin Daly, MD, is working to develop a blood test that can be used to diagnose post-transplant coronary artery disease. This test could lead to a reduction in the number of painful cardiac catheterization procedures for pediatric heart transplant recipients. Our hope is that a blood-based test may even lead to earlier diagnosis and earlier treatment for post-transplant coronary artery disease thus reducing the need for re-transplantation. We are also exploring innovative approaches using PET and ultrasound imaging to diagnose heart transplant rejection. These non-invasive imaging approaches can be performed using a simple IV and specialized imaging equipment. Such an approach would help reduce the need for painful cardiac catheterization procedures and biopsies of the transplanted heart to diagnose rejection.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”