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PHACE was recognized as a condition relatively recently. PHACE (sometimes also called PHACE association, PHACES syndrome, PHACES association or Pascual-Castroviejo type II syndrome) is an associated collection of disorders characterized by a large infantile hemangioma (benign tumor, presenting as a strawberry mark) on a child's face, scalp and neck, together with a combination of defects in the brain, blood vessels, eyes, heart and chest.
The cause of PHACE is unknown, and the condition is uncommon. Its name is an acronym describing the collection of anomalies that together comprise the condition:
Some people also add an S to the end of the condition's name, referring to abnormalities in the sternum (the breastbone) seen in some children with PHACE.
Every child diagnosed with PHACE has a different combination of anomalies and symptoms. As such, the care of every child with PHACE is highly personalized and may require the expertise of clinicians and specialists from several medical fields.
How Boston Children's Hospital approaches PHACE syndrome
The Vascular Anomalies Center's (VAC) interdisciplinary team of clinicians cares for children with PHACE syndrome who come to Boston Children's Hospital. The VAC's 25 physicians—representing 16 medical and surgical specialties—are experts in the field of vascular anomalies.
Specialists from multiple disciplines come together to care for every child seen at the VAC clinic. It's not uncommon for children on their first visit to the clinic to be evaluated by a whole team at the same time. From there, the team works with you to develop and carry out a comprehensive and coordinated care plan that matches your child's specific needs, bringing in the expertise of other Boston Children's departments and services as necessary to provide your child with the best care.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”